LOCUS       NM_001083936            2269 bp    mRNA    linear   ROD 11-OCT-2024
DEFINITION  Mus musculus parathyroid hormone 1 receptor (Pth1r), transcript
            variant 3, mRNA.
ACCESSION   NM_001083936
VERSION     NM_001083936.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2269)
  AUTHORS   Almubarak,A., Zhang,Q., Zhang,C.H., Abdelwahab,N., Kume,T.,
            Lassar,A.B. and Berry,F.B.
  TITLE     FOXC1 and FOXC2 regulate growth plate chondrocyte maturation
            towards hypertrophy in the embryonic mouse limb skeleton
  JOURNAL   Development 151 (16) (2024)
   PUBMED   39012257
REFERENCE   2  (bases 1 to 2269)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2269)
  AUTHORS   Amano,K., Okuzaki,D., Kitaoka,Y., Kato,S., Fujiwara,M., Tanaka,S.
            and Iida,S.
  TITLE     Pth1r in Neural Crest Cells Regulates Nasal Cartilage
            Differentiation
  JOURNAL   J Dent Res 103 (3), 308-317 (2024)
   PUBMED   38234039
  REMARK    GeneRIF: Pth1r in Neural Crest Cells Regulates Nasal Cartilage
            Differentiation.
REFERENCE   4  (bases 1 to 2269)
  AUTHORS   Tsutsumi-Arai,C., Arai,Y., Tran,A., Salinas,M., Nakai,Y.,
            Orikasa,S., Ono,W. and Ono,N.
  TITLE     A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via
            Runx2
  JOURNAL   J Dent Res 103 (1), 91-100 (2024)
   PUBMED   38058151
REFERENCE   5  (bases 1 to 2269)
  AUTHORS   Ling,Z., Crane,J., Hu,H., Chen,Y., Wan,M., Ni,S., Demehri,S.,
            Mohajer,B., Peng,X., Zou,X. and Cao,X.
  TITLE     Parathyroid hormone treatment partially reverses endplate
            remodeling and attenuates low back pain in animal models of spine
            degeneration
  JOURNAL   Sci Transl Med 15 (722), eadg8982 (2023)
   PUBMED   37967203
REFERENCE   6  (bases 1 to 2269)
  AUTHORS   McCuaig,K.A., Lee,H.S., Clarke,J.C., Assar,H., Horsford,J. and
            White,J.H.
  TITLE     Parathyroid hormone/parathyroid hormone related peptide receptor
            gene transcripts are expressed from tissue-specific and ubiquitous
            promoters
  JOURNAL   Nucleic Acids Res 23 (11), 1948-1955 (1995)
   PUBMED   7596823
  REMARK    Erratum:[Nucleic Acids Res 1995 Aug 11;23(15):3082]
REFERENCE   7  (bases 1 to 2269)
  AUTHORS   Karperien,M., van Dijk,T.B., Hoeijmakers,T., Cremers,F.,
            Abou-Samra,A.B., Boonstra,J., de Laat,S.W. and Defize,L.H.
  TITLE     Expression pattern of parathyroid hormone/parathyroid hormone
            related peptide receptor mRNA in mouse postimplantation embryos
            indicates involvement in multiple developmental processes
  JOURNAL   Mech Dev 47 (1), 29-42 (1994)
   PUBMED   7524627
REFERENCE   8  (bases 1 to 2269)
  AUTHORS   Kong,X.F., Schipani,E., Lanske,B., Joun,H., Karperien,M.,
            Defize,L.H., Juppner,H., Potts,J.T. Jr., Segre,G.V.,
            Kronenberg,H.M. et al.
  TITLE     The rat, mouse and human genes encoding the receptor for
            parathyroid hormone and parathyroid hormone-related peptide are
            highly homologous
  JOURNAL   Biochem Biophys Res Commun 200 (3), 1290-1299 (1994)
   PUBMED   8185578
  REMARK    Erratum:[Biochem Biophys Res Commun. 1994 Jun 15;201(2):1058. doi:
            10.1006/bbrc.1994.1811. PMID: 8002976]
REFERENCE   9  (bases 1 to 2269)
  AUTHORS   Pausova,Z., Bourdon,J., Clayton,D., Mattei,M.G., Seldin,M.F.,
            Janicic,N., Riviere,M., Szpirer,J., Levan,G., Szpirer,C. et al.
  TITLE     Cloning of a parathyroid hormone/parathyroid hormone-related
            peptide receptor (PTHR) cDNA from a rat osteosarcoma (UMR 106) cell
            line: chromosomal assignment of the gene in the human, mouse, and
            rat genomes
  JOURNAL   Genomics 20 (1), 20-26 (1994)
   PUBMED   8020952
REFERENCE   10 (bases 1 to 2269)
  AUTHORS   Seldin,M.F., Mattei,M.G. and Hendy,G.N.
  TITLE     Localization of mouse parathyroid hormone-like peptide gene (Pthlh)
            to distal chromosome 6 using interspecific backcross mice and in
            situ hybridization
  JOURNAL   Cytogenet Cell Genet 60 (3-4), 252-254 (1992)
   PUBMED   1354597
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB614354.1, BC051981.1 and AI607947.1.
            
            Transcript Variant: This variant (3) represents the longest
            transcript. Variants 1, 2, and 3 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051981.1, SRR7345562.3290190.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-129               BB614354.1         2-130
            130-2217            BC051981.1         1-2088
            2218-2269           AI607947.1         1-52                c
FEATURES             Location/Qualifiers
     source          1..2269
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 60.56 cM"
     gene            1..2269
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /note="parathyroid hormone 1 receptor"
                     /db_xref="GeneID:19228"
                     /db_xref="MGI:MGI:97801"
     exon            1..385
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            386..488
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            489..623
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            624..734
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            735..853
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            854..948
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1144
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1298
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1359
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1426
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1521
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1663
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1705
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1706..2255
                     /gene="Pth1r"
                     /gene_synonym="PPR; Pthr; Pthr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggatgtgat ttctccgctc cgaggcagac aggccgctca gcagcgctcg gcgcccgccc
       61 gccgcccgcc cggcctcagg ctgcctccct ccctccgccc tccctctctc cattgcgccg
      121 gttcgttctc tcgctcgccc tcggcgaatg ggccccgcgt cgggctccgg ggcctccggc
      181 cgcccggacg ccggggtccc ctaggccggg gcgtgggcgg ggcggcccgg cctgacgcag
      241 ctctgcaccc tccaaccatc accagggccg gcggcggctg ccccgaggga cgcggcccta
      301 ggcggtggcg atggggaccg cccggatcgc acccagcctg gcgctccttc tctgctgccc
      361 agtgctcagc tccgcatatg cgctggtgga cgcagacgat gtctttacca aagaggaaca
      421 gattttcctg ctgcaccgtg cccaggcgca atgtgacaag ctgctcaagg aagttctgca
      481 cacagcagcc aacataatgg agtcagacaa agggtggacg ccagcatcta cgtcagggaa
      541 gcccaggaaa gagaaggcac cgggaaagtt ctaccccgag tctaaagaga acaaggatgt
      601 gcccaccggc agcaggcgcc gagggcgtcc ctgtctgcca gagtgggaca acatcgtttg
      661 ctggccattg ggggcaccag gtgaagtggt ggcagtacct tgtcccgatt acatttatga
      721 cttcaaccac aaaggccatg cctacagacg ctgcgaccgc aatggcagct gggaggtggt
      781 tccagggcac aaccggacgt gggccaacta cagcgagtgc ctcaagttca tgaccaatga
      841 gactcgggaa cgggaggtat ttgaccgcct gggcatgatc tacaccgtgg gatattccat
      901 gtctcttgcc tccctcaccg tggctgtgct catcctagcc tattttaggc ggctgcactg
      961 cacgcgcaac tacatccaca tgcacatgtt cctgtcgttt atgctgcgcg ccgcgagcat
     1021 cttcgtgaag gacgctgtgc tctactctgg cttcacgctg gatgaggccg agcgcctcac
     1081 ggaggaagag ttgcatatca tcgcgcaggt gccgcctccg cccgccgctg ccgccgttgg
     1141 ctacgctggc tgccgtgtgg ccgtgacctt cttcctctac ttcctggcta ccaactacta
     1201 ctggattctg gtggagggac tgtacttaca cagcctcatc ttcatggcct ttttctcaga
     1261 gaagaagtat ctgtggggct tcaccatctt tggctggggt ctgccggctg tcttcgtggc
     1321 tgtgtgggtc ggtgtcagag caaccttggc caacactggg tgctgggacc tgagctctgg
     1381 gcacaagaag tggatcatcc aggtgcccat cctggcatct gttgtgctca acttcatcct
     1441 ctttatcaac atcatccggg tgcttgccac taagcttcgg gagaccaatg cgggccggtg
     1501 tgacaccagg cagcagtacc ggaagctgct caggtccacg ttggtgcttg tgccactctt
     1561 cggtgtccac tacaccgtct tcatggcctt gccgtacacc gaggtctcag ggacactgtg
     1621 gcagatccag atgcactatg agatgctctt caactccttc cagggatttt ttgttgccat
     1681 catatactgt ttctgcaatg gtgaggtgca ggcagagatt aggaagtctt ggagccgctg
     1741 gacactggca ttggacttca agcgtaaagc acgaagtggg agtagcagct acagctatgg
     1801 cccaatggtg tcacacacga gtgtgaccaa tgtgggcccc cgtgcaggac tcagccttcc
     1861 ccttagcccc cgcctgcttc ctgccaccac caatggccac tcccagctgc ctggccacgc
     1921 caagccgggc gctccagcca ttgagaacga aaccatacca gttactatga cagttcccaa
     1981 ggacgacggc ttccttaatg gctcctgctc gggtctggat gaggaggcct ctgggtctgc
     2041 gcggccacct ccattgttgc aggaagaatg ggaaacagtc atgtgactgg gcatcaaggg
     2101 gctggactgc tggcatgggc agatggacag atggaccaag aagccagagt ttggctggct
     2161 gtctattcag gactggacca ggaagacaaa aggaaaagag aaaaaaaaaa aaaaaaagaa
     2221 gggagctgtg tgtggcttcc tgtgttgtgc tcaagaaaaa aaaaaaaaa
//
