LOCUS       NM_001417837            3447 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus prostaglandin reductase 3 (Ptgr3), transcript variant
            2, mRNA.
ACCESSION   NM_001417837
VERSION     NM_001417837.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3447)
  AUTHORS   Yu,Y.H., Chang,Y.C., Su,T.H., Nong,J.Y., Li,C.C. and Chuang,L.M.
  TITLE     Prostaglandin reductase-3 negatively modulates adipogenesis through
            regulation of PPARgamma activity
  JOURNAL   J Lipid Res 54 (9), 2391-2399 (2013)
   PUBMED   23821743
  REMARK    GeneRIF: PTGR-3 is a novel 15-oxoprostaglandin-Delta(13)-reductase
            that plays a critical role in modulation of normal adipocyte
            differentiation via regulation of PPARgamma activity [PTGR3]
REFERENCE   2  (bases 1 to 3447)
  AUTHORS   Mizuno,Y., Kurochkin,I.V., Herberth,M., Okazaki,Y. and Schonbach,C.
  TITLE     Predicted mouse peroxisome-targeted proteins and their actual
            subcellular locations
  JOURNAL   BMC Bioinformatics 9 Suppl 12 (Suppl 12), S16 (2008)
   PUBMED   19091015
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124012.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13862051.1546908.1,
                                           SRR13422600.17669.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849378, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-249               AC124012.4         97741-97989         c
            250-402             AC124012.4         97334-97486         c
            403-3447            AC124012.4         88660-91704         c
FEATURES             Location/Qualifiers
     source          1..3447
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 57.53 cM"
     gene            1..3447
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="prostaglandin reductase 3"
                     /db_xref="GeneID:225791"
                     /db_xref="MGI:MGI:2444835"
     exon            1..249
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /inference="alignment:Splign:2.1.0"
     exon            250..402
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /inference="alignment:Splign:2.1.0"
     exon            403..3447
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1510
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="major polyA site"
     regulatory      3164..3169
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="hexamer: AATAAA"
     polyA_site      3188
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="major polyA site"
     regulatory      3191..3196
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="hexamer: ATTAAA"
     polyA_site      3219
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
     regulatory      3370..3375
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="hexamer: AATAAA"
     polyA_site      3388
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
     regulatory      3420..3425
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
                     /note="hexamer: AATAAA"
     polyA_site      3447
                     /gene="Ptgr3"
                     /gene_synonym="C530046K17Rik; PTGR-3; Pthr3; Zadh2"
ORIGIN      
        1 ccagcgtagg cgcaggagcg ggcggagctg atcgtgggca atgctgaggc tggcggccgc
       61 cggggcccga gccatcgtgg acatgtcgta cgcccgtcac ttcctggact tccagggctc
      121 cgccatcccc cgaaccatgc agaagctggt ggtgacccgg ctgagcccta acttccacga
      181 ggccgtcacc ctgcgccggg actgcccagt gccgctcccc ggggacggag acctcctcgt
      241 ccggaaccgc cgtccctcct ccccctcccg ctccctaaat aaaaacgacg ggacccagaa
      301 agggaggctc cccacccggc ccacccgcgc gcacccacgg tgcctgcgtt ccataatttt
      361 tagtggagca gcaacagcct ggacacacac tgcgacgttt agattcgttg gtattaacgc
      421 atctgacatc aactattcgg ctggccgcta cgacccgtcc ctgaagccac cctttgacat
      481 aggttttgaa gggattggtg aggtggtggc cttaggcctc tctgctagtg ctaggtacac
      541 agtgggccag gctgtggctt atatggctcc tggttccttt gctgagtata cagtggtgcc
      601 tgctagcatt gcaattccca tgccttcagt gaaaccagag tatctcacca tgctggttag
      661 tggcaccact gcatacctca gcctggaaga gcttggggaa ctgtcagaag ggaagaaagt
      721 tctggtcaca gcagccgctg ggggcacagg ccagtttgct gtgcagcttt ccaagatagc
      781 caagtgccac gttatcggaa cctgctcctc agacgaaaag gcagcttttc tgaaatcaat
      841 tgggtgtgat cggcccatca actacagaac agagcctgtg gagacggttc tgaagcagga
      901 gtaccctgaa ggcgttgacg tagtctatga gtctgttggg ggagccatgt ttgacctggc
      961 tgtggatgcc ttggccacca aagggcgctt gatagtgatt gggtttatct ctggctacca
     1021 aagccctaca ggactctcac caataaaagc gggagttttg ccaaccaagc tcctgaagaa
     1081 gtcggccagc ctcaggggtt tctttctgaa ccactacttc tccaagtacc aggctgccat
     1141 ggaacgtttg ctggagctgt acgctcgtgg ggacctggtg tgtgaggtgg acctgggaca
     1201 cctggctccg gatggaaggt tcattggcct ggagtccgtg tttcaggctg tcgactatat
     1261 gtacacgggg aaaaatactg ggaagcttgt tgttgagtta ccacaccctg tcagcagtaa
     1321 gctgtgacca acaggacagt gacagaaacc aaaggagaga aatgaattct ccatgcctta
     1381 aaacgaactt aatatttctt aaaaacaaaa gtatagtgtt aatgaattgc ctccctttcc
     1441 ttgggggtaa aaataatgtg cctcaatcag agttctctct ctagctaaga ggtaaaacgt
     1501 ttacatttga gtctttagtc atggacggtc tcattccaga ttttattgtt ccagggaagt
     1561 aaattaattc ctgatgtgtg agacctgatc gagtcagtat gtccccagct tgatgagatt
     1621 tttttttttt aaatcagtct tcagagagct caccgagtct cctttgcatt gaaagcagtc
     1681 gttctcgtgt caagcactga acagttgaga aagcagtgtc ggtccacctt ggattctcac
     1741 aggcagtgtg cctgaggagc cttttccccc taaaatcact aacctcccat ctaaatagac
     1801 atttgggaga gaattctcca aatttaatct tgttaagtta ttgggaaagt gatccagcaa
     1861 acagaggtgt cttaaggacg tgtatactgt gtgctggcct gaattcacat cctggttaga
     1921 ctgtctgtga aggaaaaaac tgtctgttct aggaagaaat tgctattaga accggagtgg
     1981 attctggaag agaaagctat agcgttggga gactgaaaac taatgtggac agaggaataa
     2041 gaaaactcta tgatgattca tcagtaaaag gcaaaaaaaa aggggggggc gggggaatca
     2101 caaaagggga ctcactctgg cctgggaagg gttaaaagga gactttctgt tgccaaggac
     2161 caaatctcac atagctccaa acacagtagg caccctggcc atctaaaacc acatccattt
     2221 gcttctccta agaggctcag tgtggaaagt gtgcttggtc tctggtgcag gcacgggatg
     2281 agagtcaggt gtcctgggtt gccattttgc ttcttggcct ttgagagaag cgagccacct
     2341 gctctagtgt tgtgtcctgg tgcacacgtg tctatcctcc tgcctgcctg ctgtttctct
     2401 tcacacctcg ccatagttgg tctgcttgcc cttcacctta ggtttcccaa ggctgcccac
     2461 cacttttgta gtggagtcaa aaccccacgg tgccttccta atcgaaggtg aagactgtcg
     2521 gattattttt cagtcttggg tttcagaaca tcaaacgttc tcaatgaatg ggaatgcaat
     2581 taggagcgct ctgtgaaagt cggggtgggg gggcaggttt aattctttcc ttgcatctgg
     2641 ggagcagaga gatcttgttt ctggaatggc tgttagtatc tattttacaa gattgactca
     2701 ttcccaggta cctaatgtag ctcctagcat gcacgcacaa caatacaatt tatatggtaa
     2761 atggaaccaa ataatggttt cactgaacgt tatggccgca ctgaagggaa atgtcacggt
     2821 aaatagctgc caaattatgg atcatgccga agtgtcacaa ctgcactaaa gacaaatagc
     2881 actagaggct attgccactg tgatgccttt gagttatgaa gaagggtagc aagcctgagc
     2941 agggctcttt gtgtcctcgt catagcagag ggttgccgga gcaggggaca agaaaggctc
     3001 ttccagtgtg atgcttagtt attaatctgt ccctttcaga cctagccact gtaacaggag
     3061 agacctcgct ggctctcttg tatacaaaca taacaaacgg gggggggggg ctttatgaat
     3121 gtcagaatgc tcaggaaatg actggtaatg gaaaaaatgt tgtaataaaa taatctaatc
     3181 aaagactatt attaaattta acatagtata tgtctgaaag gcttagttgc ttgctatgca
     3241 gatagatgtg tgaaatctca ctgataatgc tctccctctg aaaaggcttc aggactgagg
     3301 acattaccag ctaaattgcc tcttctgaac tgaagtgagt cccggtttcc ttcattttaa
     3361 tgggagggta ataaagatga aagaccaaca ttttatctga tggatccctt aagctatgga
     3421 ataaaaatgt attatgtttt gagggaa
//
