LOCUS       NM_011197               5786 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus prostaglandin F2 receptor negative regulator (Ptgfrn),
            mRNA.
ACCESSION   NM_011197 XM_907716
VERSION     NM_011197.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5786)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5786)
  AUTHORS   Gerber,H., Mosser,S., Boury-Jamot,B., Stumpe,M., Piersigilli,A.,
            Goepfert,C., Dengjel,J., Albrecht,U., Magara,F. and Fraering,P.C.
  TITLE     The APMAP interactome reveals new modulators of APP processing and
            beta-amyloid production that are altered in Alzheimer's disease
  JOURNAL   Acta Neuropathol Commun 7 (1), 13 (2019)
   PUBMED   30704515
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5786)
  AUTHORS   Pan,Y., Zhang,L., Liu,Q., Li,Y., Guo,H., Peng,Y., Peng,H., Tang,B.,
            Hu,Z., Zhao,J., Xia,K. and Li,J.D.
  TITLE     Insertion of a knockout-first cassette in Ampd1 gene leads to
            neonatal death by disruption of neighboring genes expression
  JOURNAL   Sci Rep 6, 35970 (2016)
   PUBMED   27775065
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5786)
  AUTHORS   Gu,Z., Imai,F., Kim,I.J., Fujita,H., Katayama,Ki., Mori,K.,
            Yoshihara,Y. and Yoshida,Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5786)
  AUTHORS   Lodato,S., Molyneaux,B.J., Zuccaro,E., Goff,L.A., Chen,H.H.,
            Yuan,W., Meleski,A., Takahashi,E., Mahony,S., Rinn,J.L.,
            Gifford,D.K. and Arlotta,P.
  TITLE     Gene co-regulation by Fezf2 selects neurotransmitter identity and
            connectivity of corticospinal neurons
  JOURNAL   Nat Neurosci 17 (8), 1046-1054 (2014)
   PUBMED   24997765
REFERENCE   6  (bases 1 to 5786)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   7  (bases 1 to 5786)
  AUTHORS   Stipp,C.S., Kolesnikova,T.V. and Hemler,M.E.
  TITLE     EWI-2 is a major CD9 and CD81 partner and member of a novel Ig
            protein subfamily
  JOURNAL   J Biol Chem 276 (44), 40545-40554 (2001)
   PUBMED   11504738
REFERENCE   8  (bases 1 to 5786)
  AUTHORS   Weng,L., Falla,N., Van den Heuvel,R., Raymackers,J., Karperien,M.,
            Van Bezooijen,R., Van Vlasselaer,P., Lowik,C. and Merregaert,J.
  TITLE     The monoclonal antibodies 18d7/91f2 recognize a receptor regulatory
            protein on mouse bone marrow stromal cells
  JOURNAL   J Bone Miner Res 15 (7), 1286-1300 (2000)
   PUBMED   10893677
REFERENCE   9  (bases 1 to 5786)
  AUTHORS   Orlicky,D.J., Lieber,J.G., Morin,C.L. and Evans,R.M.
  TITLE     Synthesis and accumulation of a receptor regulatory protein
            associated with lipid droplet accumulation in 3T3-L1 cells
  JOURNAL   J Lipid Res 39 (6), 1152-1161 (1998)
   PUBMED   9643346
REFERENCE   10 (bases 1 to 5786)
  AUTHORS   Orlicky,D.J. and Nordeen,S.K.
  TITLE     Cloning, sequencing and proposed structure for a prostaglandin F2
            alpha receptor regulatory protein
  JOURNAL   Prostaglandins Leukot Essent Fatty Acids 55 (4), 261-268 (1996)
   PUBMED   8951995
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645930.15 and AL669872.8.
            
            On Nov 17, 2006 this sequence version replaced NM_011197.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF152344.1, SRR17784651.734416.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                AL645930.15        61897-61971         c
            76-444              AL645930.15        31933-32301         c
            445-858             AL645930.15        28848-29261         c
            859-1239            AL645930.15        24615-24995         c
            1240-1665           AL645930.15        12442-12867         c
            1666-2085           AL645930.15        8041-8460           c
            2086-2087           AL645930.15        2001-2002           c
            2088-2193           AL669872.8         199568-199673       c
            2194-2499           AL669872.8         194922-195227       c
            2500-5786           AL669872.8         189714-193000       c
FEATURES             Location/Qualifiers
     source          1..5786
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 43.93 cM"
     gene            1..5786
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /note="prostaglandin F2 receptor negative regulator"
                     /db_xref="GeneID:19221"
                     /db_xref="MGI:MGI:1277114"
     exon            1..75
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..2666
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /note="prostaglandin F2-alpha receptor regulatory protein;
                     prostaglandin F2-alpha receptor-associated protein; CD9
                     partner 1; glu-Trp-Ile EWI motif-containing protein F"
                     /codon_start=1
                     /product="prostaglandin F2 receptor negative regulator
                     precursor"
                     /protein_id="NP_035327.2"
                     /db_xref="CCDS:CCDS17680.1"
                     /db_xref="GeneID:19221"
                     /db_xref="MGI:MGI:1277114"
                     /translation="MGRPAPRPLLLALLSLAVCRGRVVRVPAGTLVRVVGTELVIPCN
                     VSDYDGPSEQNFDWSFSSSGSSFVELASTWEVGFPAQLYRERLQRGDILLRRTANDAV
                     ELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADALVVGPSSRPPPGLSLR
                     EGEPFELRCIASTTSPLHTHLALRWELHRGPVHRSILALSHEGRFHPGPGYEQRYHSG
                     DVRLDTVGSDAYRLSVARALSADQGSYRCVVSEWITEQGSWQEIQEKAVEVATVVIQP
                     TALQLAVPRTVSVTEGKDLDLSCNITTDRVDDVRPEVTWYFKKTPDTSLLASHMLARL
                     DRDSLVHSSPHVALSHVDTRSYHLLVRDVSKENSGYYLCLVALWAPGHNRSWHKVAEA
                     MSAPSGVSVTWLEPEYQVYLNASKVPGFSDDPTELQCRVIDTKRLEAGVRLTVSWYYR
                     MTRRNDDVVASELLAVMDGDWTLRYGERSKQRAQDGEFIFSKEHTDTFNFRIQRTTEE
                     DRGNYYCVVSAWTRQRNNSWVKSKDVFSKPVNIFWASEDSVLVVKARQPKPFFAAGNT
                     FEMTCKVSSKNIKSPRYSVLITAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASR
                     VDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPIGGSLWREAATSLSNPIEID
                     FQTSGPTFNASVHSDTPSVTRGDLIKLFCIVTVEGAVLDPDDMAFDVSWFAVHSFGLD
                     KAPVLLSSLDRKGVVTTGQRDWKSTVSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPW
                     VRSPTGSWQREAEIHSRPIFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSH
                     WCCKKEVRETRRERRRLMSMEMD"
     exon            76..444
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            445..858
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            859..1239
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1665
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..2085
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2193
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2499
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
     exon            2500..5786
                     /gene="Ptgfrn"
                     /gene_synonym="4833445A08Rik; CD9P-1; EWI-F; FPRP; Trim45"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggagagtcg ctcccgccgg ccgagcatgg ggcgcccggc gccgaggccg ctgctgctgg
       61 cgctcctgtc gctggctgtc tgccgtgggc gtgtggtgag agtccctgcg ggcaccctgg
      121 ttcgcgtggt gggcactgag ctggtgatcc cctgcaatgt cagcgactat gacggcccca
      181 gcgagcagaa cttcgactgg agcttctcgt cttccgggag cagtttcgtg gagcttgcta
      241 gcacctggga ggtgggcttc ccggcacagc tgtaccggga gcggctgcag cggggtgata
      301 tcctgttgag gagaactgcc aacgatgctg tggaactgca cataaagaat gtccagccct
      361 cagaccaagg ccactacaag tgttccaccc cgagcacgga tgccactgtc cagggcaact
      421 acgaggacac agtgcaggtt aaagtgctgg cagatgccct ggtggtgggt cccagctccc
      481 ggcctcctcc aggcctgagc ctgcgtgagg gggagccctt tgagctgcga tgtatcgcgt
      541 ctaccacgtc accgttgcac acacacctgg cacttcggtg ggaactgcac cgtggcccgg
      601 tgcaccgaag catcctagcc ctaagccacg agggcaggtt tcacccaggc cctggctatg
      661 agcagcgcta ccacagtggg gacgtacgcc tggacacagt aggcagcgat gcctaccgcc
      721 tctccgtagc ccgggcgctc tctgcggacc agggttccta tagatgtgtg gtcagcgagt
      781 ggatcacaga gcagggcagc tggcaagaaa tccaagaaaa agccgtggaa gtggccactg
      841 tggtgatcca gccgacagct ctgcaactgg ccgtgcccag gacagtgtct gtgactgaag
      901 gaaaggacct ggatctttct tgcaacatca caacagaccg tgtggatgat gtccggcctg
      961 aggtgacatg gtacttcaaa aagacacccg atacctcttt acttgcctcc cacatgctgg
     1021 cgcggcttga ccgtgattcc ctggtccaca gctcaccaca cgttgctctc agtcacgtgg
     1081 atacccgctc ttaccatcta ctggtgcgag atgttagcaa agaaaactcg ggctactatc
     1141 tttgccttgt ggccctctgg gctcctggac acaacaggag ctggcacaag gtggcagagg
     1201 ccatgtctgc cccgtctggt gtaagcgtga cctggctaga accagaatac caggtctacc
     1261 tgaacgcttc taaggtcccc gggttttcag acgaccccac ggaactgcag tgccgggtga
     1321 tagacacgaa gcgtctggag gccggtgtcc gacttaccgt gtcgtggtac tatagaatga
     1381 cccgtcgcaa tgacgacgtg gtggccagtg agcttctcgc agtcatggat ggggactgga
     1441 ctctgagata tggagagagg agcaagcagc gggcccagga cggagagttt attttttcta
     1501 aggagcacac agacacattc aatttccgga tccaaaggac tacggaggaa gacaggggca
     1561 attattactg tgttgtgtct gcctggacca ggcagaggaa caacagctgg gtgaagagca
     1621 aagatgtctt ctccaagcct gtcaacatat tctgggcctc agaagattct gtgctcgtgg
     1681 tgaaggcacg gcagccaaag cctttctttg ctgcagggaa tacatttgag atgacttgca
     1741 aagtgtcttc caagaatatt aagtcgccac gatactcagt tctcatcacg gctgagaagc
     1801 ccgtcgggga cctctccagt cccaacgaga ccaagtacat tatctccctg gaccaggact
     1861 ccgtggtgaa gctggagaac tggaccgacg cgtctcgggt ggatggcgtg gtgttggaga
     1921 aagttcagga ggatgagttc cgataccgaa tgtaccagac tcaggtctcc gatgcgggcc
     1981 tgtaccgctg catggtgaca gcctggtctc ctattggggg cagcttgtgg cgagaggcag
     2041 cgaccagtct ctccaatcct attgagatcg acttccaaac ctcaggtccc acatttaacg
     2101 cctctgtgca ttcagacaca ccatccgtca cccggggaga tctcatcaaa ttgttctgta
     2161 tcgtcactgt ggaaggagct gtgctggacc cagatgacat ggccttcgat gtatcctggt
     2221 ttgcggtaca ctcttttggc ttggacaagg ctcccgtcct cctctcctcc ttggaccgga
     2281 agggagtcgt gacgacaggc cagagggact ggaagagtac tgtcagcctg gagcgagtga
     2341 gcgtgctgga attcttgctg caagtgcatg gctctgagga ccaggacttt ggcaactact
     2401 actgttctgt gactccctgg gtgaggtcac cgacaggttc ctggcagagg gaagccgaga
     2461 tccactccag gcccatcttt ataactgtga agatggacgt gctgaacgcc ttcaagtacc
     2521 cgctgctgat cggcgtgggc ctgtccacag tcatcgggct cctgtcctgc ctcatcggat
     2581 actgcagttc ccattggtgc tgtaagaagg aggttcggga gacgcgtcgg gagcgccgca
     2641 ggctcatgtc catggagatg gattaagcag ttggagatgg agggacagag gaacattgta
     2701 ggagcggtgg gggtgagaag aggactctga tatttttaca accgagtgtg ttacactaaa
     2761 accagtcctc tctaatctca ggtgggactc ggcgctctct cttttctgca tgtcaagttc
     2821 tgagcgagga catgtttacc agcacacagc tcttcttccc acggcacttt ctgatatgta
     2881 acaatcgagt gtgtgtttcc cccagctgca gctttttaat ggttaacccc ccaccccacc
     2941 ccccaccccc gtctaattag ttttctccta gcggcttatc gatcctctga tttgtgtgtg
     3001 ttgctcactt ttgatttagg gatctcggtg aggtagggcg aaggcattca gagttggtca
     3061 ttgtgggtaa gagggtaccg gcccacccga aagccagcat ccacgagcag ccagcatcgg
     3121 gagagctgct acctgctgcc ctccaccctg gctcagagct gatatagacc tgtgccaagg
     3181 caagctgtgg ctttgactgc cctgcccatc ccccattgtc aggggtttaa aactctataa
     3241 cttcttggcc cgtaagcctt ttgtttcccc tccttctcta ccctcttccg ttttccgggt
     3301 ttgtttctgt gagtgaggat acggcagccc tggagtctag aattcggctt tccaccaagc
     3361 accttatctc gccaccttag ccttaagaat gagtatgaaa aaaatccagc accacctctg
     3421 tccagggcag aaggtctggg aggaggagga ggaggaggac acgggggggg gggggggggg
     3481 gaggaggggg gcgggggggg gggaggaact gatgctcgcc cacccacgtg ctcgctctgg
     3541 tagttcttag gccactgtgc tccaggaacc ccagggtgag tgggagcaga gggcagccgt
     3601 gccgccgagc caggtgccct gtcccttcat gagaggcact gtccctggtg ccacaggacc
     3661 gccatgggag ccacaaaagt gccacattga gcttcttcac aggaaggcag gttgctgcct
     3721 gcaagactga cggacttcaa ggaatcagaa attgcctaga gcaagcgtgt gttctccatg
     3781 accttttcag tccttgaagt ctttctaagc tccccgcagg gggtagtgaa gaggggtata
     3841 ctttgtgaac gtttgctttc ctattagaaa catgaaggga acccagctat ttagtgttat
     3901 gtgaatggcc tgtaaaatag ggttgagagc agctgcctct gcctggctgg gcccagcagg
     3961 aacgggacag cgggcaggca catcttccag gtcaccagtg cctgctccat cagggcctca
     4021 gccacacaga ttctctcacc tcagcatagc cttcctgagc ctcccctgag tactgaggct
     4081 caccacccag ctggtaccct cgccctgcct tctgcctctg aaggatttaa cattgttgtc
     4141 ttccaagggg ggacggggag aagagtcctt tctcttaagc aataaagtaa tccgaaaaca
     4201 tggccatcac gtgcagctct agtcaacacg gaccaggatg cgctgagccc ccacccccac
     4261 ccccgccttc tctccatgtg gcccacggtg gcttttgtat tttccaccca atttcctctg
     4321 cttgttttga gcccaccttg ggggctgctc gtgtaatgag attttgagaa ggtagctcta
     4381 gcccaggtgg ggtccaggtt tagagtcagt agcagatgca ccccacacaa gcaagagagg
     4441 ccagagaaag gggaggcttg gcagacacgg ttggtctaca tgtcgctttc ttgttgctag
     4501 ctcagacgtg aggcacaggt gactgtacaa acaggaatta ggggagagaa ccaggtgtta
     4561 ggagcagcct tcgagcctgt gccattactg aagaagattc agggtcttgg cagtacagcc
     4621 ctccttagga ggatgagaga gacttagcct ggggtgagat gagccctaga tgtacataaa
     4681 gccacagtgg tccacgtggg tactggatga tgagatgagt gatcggacct acctttccct
     4741 ttcgtctgat gttgagattt gaacctgagt tgtggaggcc atgcccaaac ccccatgttg
     4801 cttagggttg ggagaggggc cagaaacctc aggacctagt tccttttggg aatcttacca
     4861 tgctggggtg tgtgtcttgt taagtgtggt caaacactct tgatgtacca aatagtgctc
     4921 cccatgaagc gctcttcctg aggcccccac cctgcaacac tgctctgggg gagggagagg
     4981 ccgagccagg ccttggcaca tgaaattgca cttcttaaag agaaaacttt atagaaggtt
     5041 gggtattttt cctaatcaca aaaatctccc gctgaaagaa cctaagctac attcagattg
     5101 aagcctcgaa aattacttta aattgtttac tttacgatgt ttacacacac ggctcacttt
     5161 tttagaaaaa taagaaaact gcaaactctg gctttttaac aacttttcag attttttcat
     5221 gcatgggata tgctggcccc tgactcacca gctggattaa tcctcattta gaaatgtccc
     5281 gagatgtgga tatgtgtgtc ttccccctcc cagccacatg cccagacctc tgtctgtttc
     5341 tctggtggct tttgcctcct gctttgcaga ccgcctgcag ccatgatttt gttacggcat
     5401 ccatgagcca aagactgcgc ttcggagcag gaactgtaag caatactaca caacttgcta
     5461 cttttggggg gaattttttt tttaacttca ctcatgacaa cagaggaaga aaggaattga
     5521 ggtttaggta agttctcttc cactgtgtga ccagattctc ggtgacacac aattgtgcag
     5581 atcactagga gaaggaggtt gggtttcttt tctagtgtgt aacacgagga tctgcagaat
     5641 ttcccataga caaagagaag gtcttgtgta tttttgtccc tatccaaggt tatacaaact
     5701 aattgtgttg ttttatactg tgcccacaaa tattatgcaa tgcaccattt gtttttgtct
     5761 ttattttatt aaaggaagtt taattt
//
