LOCUS       NM_026873               1675 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus pentatricopeptide repeat domain 2 (Ptcd2), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_026873 XM_127497
VERSION     NM_026873.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Xu,F., Ackerley,C., Maj,M.C., Addis,J.B., Levandovskiy,V., Lee,J.,
            Mackay,N., Cameron,J.M. and Robinson,B.H.
  TITLE     Disruption of a mitochondrial RNA-binding protein gene results in
            decreased cytochrome b expression and a marked reduction in
            ubiquinol-cytochrome c reductase activity in mouse heart
            mitochondria
  JOURNAL   Biochem J 416 (1), 15-26 (2008)
   PUBMED   18729827
  REMARK    GeneRIF: PTCD2 protein is involved in processing RNA transcripts
            involving cytochrome b derived from mitochondrial DNA.
REFERENCE   2  (bases 1 to 1675)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1675)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 1675)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 1675)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC132347.4.
            
            On Nov 17, 2006 this sequence version replaced NM_026873.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025110.1, AK004502.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               AC132347.4         71931-72045
            116-208             AC132347.4         73204-73296
            209-338             AC132347.4         76579-76708
            339-456             AC132347.4         79829-79946
            457-535             AC132347.4         83643-83721
            536-627             AC132347.4         84082-84173
            628-741             AC132347.4         86544-86657
            742-816             AC132347.4         89897-89971
            817-930             AC132347.4         94935-95048
            931-1675            AC132347.4         96216-96960
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 52.76 cM"
     gene            1..1675
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /note="pentatricopeptide repeat domain 2"
                     /db_xref="GeneID:68927"
                     /db_xref="MGI:MGI:1916177"
     exon            1..115
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..1155
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /codon_start=1
                     /product="pentatricopeptide repeat-containing protein 2,
                     mitochondrial"
                     /protein_id="NP_081149.1"
                     /db_xref="CCDS:CCDS26721.1"
                     /db_xref="GeneID:68927"
                     /db_xref="MGI:MGI:1916177"
                     /translation="MATVFRPLERLRVPRPSLHPGVTGSGSACCRCTLGAKRYLLTDN
                     IVKLKEFQHKKIAIAYNLPGTKEIYFRNLEEKLTQNKLILKEELKTLLYLCQSLEDVQ
                     LAKAVIYRYHAENKNFTLGEYKFGPVFMRLCYELDLEDSAVELVRDKHLQGFFLDSTS
                     FNILMDMLFTKGKYERALQVLIEMKNQDVRFSKETYILAFAICYKLNTLESLKICTTL
                     REEALIKGDIICRRAYCFVVALALNKNQLKNAVSIFSQIVNPESIVCINLNILIHIQS
                     NMLESLLKILEDSLDTNLSKFVRRHTFSEEVLAKVREKLKDSPALIARFDEVYGKLHV
                     NGQITVHSLDALLCHVPRDKRSNLLLLKKRAVSHRTLQPLSRSLLTE"
     exon            116..208
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            209..338
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            339..456
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            457..535
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            536..627
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            628..741
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            742..816
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            817..930
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1675
                     /gene="Ptcd2"
                     /gene_synonym="1190005P08Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaacaaca tggctacagt gtttcggccc ctggaacgcc tgcgggtgcc gcgtccttcg
       61 ctgcatcccg gggtgacggg ctcaggctcc gcctgctgcc gctgcactct cggagctaaa
      121 agatacctac tcacagataa cattgtgaag ttaaaggaat ttcaacataa gaagatagct
      181 attgcatata acctacctgg caccaaagaa atctatttca gaaacttgga agagaagttg
      241 acccagaaca aactcatctt gaaggaagag ttgaaaacgc tgctgtacct gtgccagtcc
      301 ctggaagatg tgcagctggc gaaagccgtc atttataggt accatgcaga aaacaagaat
      361 ttcactttgg gggaatacaa gttcggacca gttttcatga ggctgtgcta cgagctggac
      421 ctggaggact ctgcagtgga gctcgtcaga gacaagcatc tacaaggctt cttcctagat
      481 tcaacgtcat tcaatatttt gatggatatg ttatttacca aaggcaaata tgaacgtgca
      541 cttcaagtgt tgatcgaaat gaaaaaccaa gatgtgaggt tcagcaaaga aacctacatc
      601 ctcgcttttg caatctgcta caaactgaat accctggaat cgcttaaaat ctgtactacg
      661 ttaagagaag aagccctaat taagggagac attatctgca ggagagcata ctgttttgta
      721 gtggcattag ctctgaataa gaaccagttg aaaaacgctg tgtccatttt ttctcaaatc
      781 gtgaatccag aaagcatagt gtgtattaac ttaaatatct tgatccacat ccagtcaaat
      841 atgttggaaa gcctgttaaa gatcttagag gactctcttg acacaaattt atcgaaattt
      901 gtaagaagac acacattctc agaggaagtg ctggccaaag tgagggaaaa actgaaggac
      961 agccctgcac tcatagccag attcgatgag gtctatggga agctgcacgt gaacggtcaa
     1021 atcaccgttc attctttgga tgctctgctc tgccacgtcc cccgggacaa gagatccaac
     1081 ttgttgctgt taaagaagag ggcagtcagc caccggacct tacagcctct cagccggtcc
     1141 ctgctgaccg agtaactgct ttccatttcc ctggtctgga gcagctgctg ctacagtgga
     1201 ttactggctg ctccgggccg ggcatcttac ttacttcagt ggccctgtgc tgacgcttgg
     1261 tctccctaag tcctaagtcc cccgagtggt gacatgctac cagagaaatg ggaagagcta
     1321 gctcgagcca agggagcccc acagaaaggc agctgccctc gtttcacagg ctccagagta
     1381 agactcagag ctgctaatgc agcccagtag agtggagctc aggaggtacc cacagacggg
     1441 atttctcttg gtcttgactg acctttcacg gcagaggtga ctcgcaagtt ggtggggaga
     1501 cctgaaaccc tcatctccca tctttggaag tggcggaggc cttcctcgtc tccgccatcg
     1561 ttattccatc tgtgaggcga tgctgcctgg gtgtgcttgg atgacttcac atttccattc
     1621 aaggttcagt agagttcagc tttctccaga ataagaaata aaaggttcct gtgca
//
