LOCUS       NM_001404433            7430 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus polypyrimidine tract binding protein 3 (Ptbp3),
            transcript variant 3, mRNA.
ACCESSION   NM_001404433 XM_006537851
VERSION     NM_001404433.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7430)
  AUTHORS   Zhao,C., Zhao,J.W., Zhang,Y.H., Zhu,Y.D., Yang,Z.Y., Liu,S.L.,
            Tang,Q.Y., Yang,Y., Wang,H.K., Shu,Y.J., Dong,P., Wu,X.S. and
            Gong,W.
  TITLE     PTBP3 Mediates IL-18 Exon Skipping to Promote Immune Escape in
            Gallbladder Cancer
  JOURNAL   Adv Sci (Weinh) 11 (38), e2406633 (2024)
   PUBMED   39116343
  REMARK    GeneRIF: PTBP3 Mediates IL-18 Exon Skipping to Promote Immune
            Escape in Gallbladder Cancer.
REFERENCE   2  (bases 1 to 7430)
  AUTHORS   Monzon-Casanova,E., Bates,K.J., Smith,C.W.J. and Turner,M.
  TITLE     Essential requirement for polypyrimidine tract binding proteins 1
            and 3 in the maturation and maintenance of mature B cells in mice
  JOURNAL   Eur J Immunol 51 (9), 2266-2273 (2021)
   PUBMED   34214192
  REMARK    GeneRIF: Essential requirement for polypyrimidine tract binding
            proteins 1 and 3 in the maturation and maintenance of mature B
            cells in mice.
REFERENCE   3  (bases 1 to 7430)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7430)
  AUTHORS   Monzon-Casanova,E., Matheson,L.S., Tabbada,K., Zarnack,K.,
            Smith,C.W. and Turner,M.
  TITLE     Polypyrimidine tract-binding proteins are essential for B cell
            development
  JOURNAL   Elife 9, e53557 (2020)
   PUBMED   32081131
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7430)
  AUTHORS   Tan,L.Y., Whitfield,P., Llorian,M., Monzon-Casanova,E.,
            Diaz-Munoz,M.D., Turner,M. and Smith,C.W.
  TITLE     Generation of functionally distinct isoforms of PTBP3 by
            alternative splicing and translation initiation
  JOURNAL   Nucleic Acids Res 43 (11), 5586-5600 (2015)
   PUBMED   25940628
REFERENCE   6  (bases 1 to 7430)
  AUTHORS   Pavlinkova,G., Salbaum,J.M. and Kappen,C.
  TITLE     Maternal diabetes alters transcriptional programs in the developing
            embryo
  JOURNAL   BMC Genomics 10, 274 (2009)
   PUBMED   19538749
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 7430)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   8  (bases 1 to 7430)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 7430)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 7430)
  AUTHORS   Huttelmaier,S., Illenberger,S., Grosheva,I., Rudiger,M.,
            Singer,R.H. and Jockusch,B.M.
  TITLE     Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and
            microfilament attachment proteins
  JOURNAL   J Cell Biol 155 (5), 775-786 (2001)
   PUBMED   11724819
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL824704.27.
            
            On Apr 9, 2022 this sequence version replaced XM_006537851.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.140903.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-758               AL824704.27        198683-199440       c
            759-792             AL824704.27        196301-196334       c
            793-874             AL824704.27        174547-174628       c
            875-1044            AL824704.27        167738-167907       c
            1045-1191           AL824704.27        164426-164572       c
            1192-1356           AL824704.27        151462-151626       c
            1357-1467           AL824704.27        144652-144762       c
            1468-1642           AL824704.27        143338-143512       c
            1643-1720           AL824704.27        138263-138340       c
            1721-1860           AL824704.27        135759-135898       c
            1861-1894           AL824704.27        135491-135524       c
            1895-1987           AL824704.27        132697-132789       c
            1988-2204           AL824704.27        131514-131730       c
            2205-2282           AL824704.27        127307-127384       c
            2283-7430           AL824704.27        122020-127167       c
FEATURES             Location/Qualifiers
     source          1..7430
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 32.57 cM"
     gene            1..7430
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="polypyrimidine tract binding protein 3"
                     /db_xref="GeneID:230257"
                     /db_xref="MGI:MGI:1923334"
     exon            1..758
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     CDS             745..2415
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="isoform 3 is encoded by transcript variant 3;
                     regulator of differentiation 1; ROD1 regulator of
                     differentiation 1"
                     /codon_start=1
                     /product="polypyrimidine tract-binding protein 3 isoform
                     3"
                     /protein_id="NP_001391362.1"
                     /db_xref="GeneID:230257"
                     /db_xref="MGI:MGI:1923334"
                     /translation="MSDIVVVTDLIAVGLKRGSDELLSSGVINGPSTMNSSTSAGVYA
                     NGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAF
                     LEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSA
                     VQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITF
                     TKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRD
                     FTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPG
                     ALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRV
                     KIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQG
                     LTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKA
                     FKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI"
     exon            759..792
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            793..874
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1044
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1191
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1356
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1467
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..1642
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1720
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1721..1860
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..1894
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..1987
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            1988..2204
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2282
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     exon            2283..7430
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4083..4088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="hexamer: AATACA"
     polyA_site      4104
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="major polyA site"
     regulatory      7241..7246
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="hexamer: ATTAAA"
     polyA_site      7261
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="major polyA site"
     regulatory      7400..7405
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="hexamer: AATAAA"
     polyA_site      7430
                     /gene="Ptbp3"
                     /gene_synonym="5830471K22Rik; Rod1"
                     /note="major polyA site"
ORIGIN      
        1 actcttcctt ccacctctga ccggccggag ctgcggagcg gctccgctcg ctggtttccc
       61 ggagccgccg cccgctttct ccgcccgcgg tgagcccgtc aatccccgca caacgcgctc
      121 ctccatctgg gccatggatg ggtaagtgcc gggtggccgt tccggggctg cgctggcctc
      181 gtttcctctc ggcgacgcgt cccgccgagg ccggggagca gggcgcgacg ccggctagcg
      241 gaggagcggc ccggggctaa gcccgacggc agggaccttg ggagcgcggg ggtctgtccg
      301 ccgcggtctc cgcttcctgc gcgcggcgcc cccgtcacgt ccgcccctcg cagcctcggg
      361 gcgccttcgg gaagcagaga cgagccaggg ccggggtgcc gggccggact ccccacactt
      421 cctctcagaa aatggtgcgc ggcgctggcg ggggcggagg ctgaggcggc cgcggcgctc
      481 ggggagttgc tgtttaccgg tggggtgggg cgcgcggcgg agctttcccc cggcggcggg
      541 cccgggcgag cggcgacagc cgtctgggcg gcgaccgggt ctcgaactgc gggcccgtgc
      601 gggtctcgga accggcgggg tctcccgatt tgggctgtga gatacgttaa ccacttctaa
      661 ataccgagcg tctgcacttt atcaccaggg acgcttcctc ttcgttcccc acccccaaga
      721 aacttcgtga attcgcctcg ggcgatgtca gatattgttg ttgttacaga tcttatagca
      781 gtcggtttaa agcggggatc tgatgagctt ctgtcttctg gtgtcattaa cggaccttct
      841 accatgaaca gctcgacttc tgcaggtgtg tatgctaatg ggaatgacaa caagaaattt
      901 aaaggagata gacctccctg ttcgccttcc cgtgttctcc atcttcgaaa aattccatgt
      961 gatgtcaccg aagcagaggt catatcatta ggtctaccat ttggcaaagt aactaatctt
     1021 ttgatgttga aaggaaaaag ccaggccttt ttagaaatgg cttctgaaga agctgctgtt
     1081 actatgataa attattacac tcctgttact cctcatcttc gaagtcagcc tgtttatatc
     1141 cagtattcca atcaccgaga acttaagact gacaatctgc ctaatcaggc tagagcccaa
     1201 gctgcactgc aggctgtcag tgcagtccag tcaggaaact tgtcccttcc tggagctact
     1261 gcaaatgaag gcacattgct acctgggcag agccctgtgc tccggataat tattgaaaac
     1321 ctattttacc ctgtcactct ggaagttctc catcagatat tttctaaatt tggcacggtg
     1381 ttgaagatta tcacctttac aaagaataat cagtttcaag ccttgcttca gtatgccgac
     1441 ccagtgaatg cgcagtatgc caaaatggct ctggatggcc agaatatcta caatgcgtgc
     1501 tgcactctcc gtattgactt ctccaagctc accagcctta atgtgaaata caataatgac
     1561 aaaagcagag acttcactcg cttagacctt cctactggtg acggccagcc atctcttgaa
     1621 cctcctatgg ctgctgcttt tggtgcaccg ggtataatgt cctctccata tgcaggggct
     1681 gctggctttg ccccagccat cgcatttcct caagcagcag gtctgtctgt cccagctgtt
     1741 cccggagccc ttggtcctct cacacttacc tcctctgctg tcagtggaag gatggccatt
     1801 cctggggcaa gtggtatgcc tgggaattct gttctgctgg tcaccaacct caatcctgac
     1861 tttatcacac cacatgggct ttttatccta tttggagtgt atggtgatgt acatcgagtg
     1921 aagattatgt ttaacaagaa agaaaacgcc ttggtgcaga tggcggatgc gagtcaagcc
     1981 cagctagcaa tgaaccacct aagtggtcag aggctctatg gaaaagtact tcgggctaca
     2041 ctgtccaaac atcaagccgt ccagctccct agagagggac aggaagacca aggtctgacc
     2101 aaggacttca gcaatagtcc cctgcatcgc tttaaaaagc ccggctcaaa gaatttccaa
     2161 aatatcttcc ctccatcagc cacacttcat ctttccaaca ttcctccttc tgtcacaatg
     2221 gatgacctga agaacctgtt cacagaagct ggatgctcag tgaaggcttt taagttcttc
     2281 cagaaagacc gtaagatggc tctcattcag ttgggatctg tggaagaagc aatccaggct
     2341 cttattgagc ttcacaatca tgaccttgga gagaatcacc acctcagagt ttccttctca
     2401 aaatccacca tctgaccttc ccgtgaaatt gtctccttat actggaccac agtttctgta
     2461 agatcttcag gcacagactg aagcagctca agaccatttc tgcctcttca caaaataact
     2521 cttcgggaat ttgatattcg agaacagtca aaacaagaga gagtcctttt cttcctctcg
     2581 ttttccccaa cagtgtatga tcaaaagttt gctttgcctt tgtattgtgg tttctatgaa
     2641 aataactttc ggggggaaaa aatcaggaaa atctttttaa aataatttaa ttccctgaat
     2701 gagatttaaa aaggacagag tttctttctg tttgggtcca gagcagcctt acatgacatt
     2761 tctaaactcc tttgtacttt gagaaattta aacatacaga cttttacaat ttcttgatgt
     2821 aatttaaatc acctacaacc aagttttttt aactttatga ttcagaagtt tccctgtaga
     2881 aaatgacatt cattcactta taaaaattat accagatatt tgcatctatt gatagttatt
     2941 atacataact acatggagat atattggaaa caggtttata aacgtgcatg ctttctttca
     3001 gatttctttt ttccccccac tgtagcacac tcctttaaat aatgtccatc ttctcttttt
     3061 aagaccattt ggaaaagcaa agtgttgcag ttgtccccag ggaaacagaa gtgaaattca
     3121 gcctggatct tttacaatat cagcataatt agtcatttta ggaaaaaaaa tcatgtttta
     3181 aatttcaaaa tgacactgtc tagtaatgta atgtgatctt ggaaaatttt aaaagaaaaa
     3241 taatcctact tttttataat tgttttcaga aaaaaagttt acagtcttaa ggaaaaatat
     3301 tcaggtctat catatggttt gacagatttt ttaaaagtta tttttggtaa ggtcttcttt
     3361 tagaaaaaaa aatctcaagg gttttttgta ccactataat ctctaatact cagaattact
     3421 gtgtatttac ttaatttctt attatgtgcc ttattatgtg cttaagatac aatagattag
     3481 aattttatct aaatatctag aaagataaat tgtgggcttg gtgagcattc tgttattttt
     3541 tcctgtcttg gattttaagg gttttggttg tttttgtttt gtttttttct ttttttctcg
     3601 ttgcaatttt aagtggtttt caataagtaa tagtttctac tcagattttt ggtgctttgg
     3661 gatagtggtg ggatagagaa gggtgagtgg attgggaata aataactcag tgtgcacctg
     3721 taggcctctc taggttggct gccgccagcc gtcagggaag tctgagctgt agacctgcag
     3781 actcggatct ctgtctgtct gccttcactg cccgttagat tttgtctcag gattacttga
     3841 ttccttctca gcactcaagt gagaacctga ttttctctgt taatgcgact tcattacaga
     3901 tagcccacat atttggagta tgagaaagtg ggttattttt ttatattctg accctcttac
     3961 ttttttggtt gaatgtaaaa agtacatatt aatgttgctt caatgattgt gtcatgtaaa
     4021 attacttttt aatatgaaac tgcttttgtt aattatttct tcaatgcgtg attggctttt
     4081 aaaatacaga atttgtcaga ggaatcaatt ttgtccaccc cttctcactt ttaataatct
     4141 cagagtggat catctcatct ttttaaaata tctcagtctt tactttcagc cattaatttg
     4201 aacattcttt taaaaaaaaa aaagaatgaa ggaaagaaaa aaattgtata agctgaaaga
     4261 taattatagg ttgaagtcaa atcagaattc cctcaataca gagcaactat tggtaggcta
     4321 ggcagggaaa tgctagattg ggacgtttca gatgggttac cttcatgttg gttgaatagt
     4381 taggtatgat gattttccag tgggtgtttt cccacttaca tctgaggtgt attttcacct
     4441 gaatactgaa taagggaggg aaaaaattag gactgtctcc ccaaatttgc ttttttttcc
     4501 cctcacacag acattatctt aattttcagt ggcattttaa attggattgc ttcctttatt
     4561 ttgagttggg aactactatg taatttatta attcatggca ctcatatcat ccagcataag
     4621 tgtagcaaaa gtttttgaga atagaaggga aatcatactg gtgttgaatg taattctgaa
     4681 gtagggatgg cctttaaata tgagagagaa cattgaaatc cttttcaggg atttgtgtag
     4741 atatgtgtgc gtgtgtatgt gtgtgtataa ataagtgtat atacatacat atactctttt
     4801 aatgttatat atacatgtgc acattacata cattttaatt tattgacaaa attaacagtg
     4861 atttgggaac gtaagatatg cttgttttaa aagagcatgt ttgaagccat cagattgtgt
     4921 ctaaaattag ctgtagcata tggatgctgt ccatatttga gctctttact gtttattata
     4981 gaggtctaca atatttgtgt tggcatagtt ttaaatatca gggtggtggg aaaattcgat
     5041 ctgtgtattt ttattttagc atgcagtatt cagtatcttt taagcagtgg ttaatttgtg
     5101 ctgttgatgc cttgctgagt taatctactt tatttttcac ttttcaaggt atcctgactt
     5161 ttacaaagca tatatattca ggacttagaa aatagcagta cacatttaat aatagagtta
     5221 tatatcaaga tgttttactt tgggatttag atgtgttttg tgacagatga gaatatacaa
     5281 gtcatgcatt ctcttaattg acaatttgtt agaatttcag gattacctgg tatccccata
     5341 gaatgttatg cgatctttgg gactaaatac tacaagcagc tctttgtagc agtgtttgca
     5401 ctgaatgttt tagagtcatg gttgctgtct ttttagttcc ttctttgtct tttcctactg
     5461 tggtgattaa gggtcctgtt gtggttttgg aattagccct tatgatccag gcatagtagc
     5521 acacagctgc aattgaagca ctggaggaaa ctgatggttg tgactttaaa cccagcctgg
     5581 actgcagacc atgctccatg ctagtcttgc taagatcctg tgtccttccc tttccccagt
     5641 taatctacta tcaactttaa agtcttcatg tcatcaagca gagcatttac ttgagtatat
     5701 tatcgtgcag ttcctcatct agtcccataa tgatcttttg tgcctcagtg aatctacttg
     5761 taaactccaa gcttatctct tagaaaaccc agtgtgtact gctattttta gaaccaaaaa
     5821 gcatgactat gattggagca tttttctcag cctttccttt gtcttgatct attgtcaatt
     5881 cgaataaaac tgccagactt aaaatactca ctatcgtgct aaaacaaaca gtttagattg
     5941 tacataactt tgcagtgtaa ctcagctgtc tccttaagga ttgtgttaga tataagactg
     6001 tttgcagtcc ttttttcaga gcaaatccta acaggtactt gtgaattgtt ttaaaaatag
     6061 aaaattacag aaatcttaat ttggggtggg agcttaaagg gagaaaaaca aaacaggacc
     6121 aaagtttatg tgccttcttc agtagtctta attgaccttt tcctatttga gactaaggta
     6181 gcactggtat tttggttttc aggaaatatc tactatatag attaagagac tattgtccct
     6241 caaactggtc atacaagtga ctagttatga ctgagttaaa aagtcagcta cacttatgcc
     6301 ttcagcatta tgtgttacca gttgaagagc agaactgctc tcggtcttta tggtagtcac
     6361 cgtagctttc gcagcttgtc aggggccttg gtgttgatag cagtcataac cgaaagctgc
     6421 tcatagcaaa tttcacttca cactgtcagc agaggtttgt tggtatgtcc tttgtaagaa
     6481 caggtatttt aggtaggagg tttttggttt tgtttttgtt ttggcgtctt taagactatc
     6541 atcctctagt cttttttgtt tcttggttgt cttttgttat ttgttttttt ccttgccact
     6601 cattgttacc cagatcttta aaaacacatc ccatatccag gaagtactaa tcaccaagat
     6661 tgctgaccac accaagtttt acactgaagt ttcacctcat tgctctgacc aaagactgct
     6721 tgttctggtt ttaactcaaa ggtgaagcat tttccctgag ctctttccta aaagatccca
     6781 tgcagagcgg ccttgacttt tcctttccta ttggtgaata gactacttag agaaaatggg
     6841 agttgaccat gaacagagcg agacagaagg atggacggtt gttttcagaa ctgtatttga
     6901 ggaaggaata gcacagctag acgcctcgaa cattgtctaa tgttttacat ggtctgttca
     6961 taaaattccc ttttctgttt gtaaggatgt tcatctaaca gaagaaaatg ctgtaaatat
     7021 ttgtaacaac attttttaaa ccaggccaaa aagaaaaaaa aaaaaggttt tcgggaacaa
     7081 gttaacatat aaagtggttt tatataaaac agcgattgtc ttgtatattt tgataagcag
     7141 cagtaccaga tttcatttgt aatacagttt gtggtattgg aagaaaagga ttctgtgatt
     7201 gtctaagtga attatgttat aaatgcaaag aggagaaaat attaaaaaac gtattttcta
     7261 actgtgtagt gcatggttaa ttcaagcttc tgtacactac aatattgatt ccgcttccct
     7321 taggtttgta tatttgataa ctgttccttg gaatctcagc ctcttttcct aacacatata
     7381 gcattgtagc atgcctttta ataaatgtca tggcatctgt actctcttaa
//
