LOCUS       NM_001101430             577 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) assembly chaperone 4
            (Psmg4), transcript variant 2, mRNA.
ACCESSION   NM_001101430 XM_884663 XM_910732
VERSION     NM_001101430.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Le Tallec,B., Barrault,M.B., Courbeyrette,R., Guerois,R.,
            Marsolier-Kergoat,M.C. and Peyroche,A.
  TITLE     20S proteasome assembly is orchestrated by two distinct pairs of
            chaperones in yeast and in mammals
  JOURNAL   Mol Cell 27 (4), 660-674 (2007)
   PUBMED   17707236
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139242.2, BC070417.1 and AA124813.1.
            
            On Sep 27, 2013 this sequence version replaced NM_001101430.1.
            
            Transcript Variant: This variant (2) represents the longer
            transcript and encodes the longer isoform (b).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AV474640.1, BF020930.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC139242.2         147212-147237
            27-548              BC070417.1         1-522
            549-577             AA124813.1         425-453
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 14.05 cM"
     gene            1..577
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /note="proteasome (prosome, macropain) assembly chaperone
                     4"
                     /db_xref="GeneID:69666"
                     /db_xref="MGI:MGI:1916916"
     exon            1..286
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..484
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /note="isoform b is encoded by transcript variant 2;
                     proteasome chaperone homolog 4"
                     /codon_start=1
                     /product="proteasome assembly chaperone 4 isoform b"
                     /protein_id="NP_001094900.1"
                     /db_xref="CCDS:CCDS49230.1"
                     /db_xref="GeneID:69666"
                     /db_xref="MGI:MGI:1916916"
                     /translation="MEESRAAADADVSLHNFSARLWEQLVHFHVMRLTDSLFLWVGAT
                     PHLRNLAVAMCSRYDPIPVCTSLFGDTSDTTSTGLAQRLARKTSKQVFVSYNLSNTDS
                     NFTLLVENRIKEEMETFPEKF"
     exon            287..362
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /inference="alignment:Splign:2.1.0"
     exon            363..554
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      529..534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /note="hexamer: AATAAA"
     polyA_site      550
                     /gene="Psmg4"
                     /gene_synonym="mPAC4; PAC-4; Pba4"
                     /note="major polyA site"
ORIGIN      
        1 tcggcgcgcg catctgaaag tgaaagagcg ttccgctttt cggagctcgc tctctctggt
       61 ctgggagccc gcgcctgccc ggtctcggtg ctgtggcccg gtggctggcg ggatggagga
      121 gtctcgggcc gctgcggacg cggacgtgtc gcttcacaac ttcagtgcaa ggctgtggga
      181 gcagctggtc cactttcatg tcatgcggct gacggattcg ctcttcctgt gggtgggagc
      241 aacgccgcat ctacgcaacc tcgcagtggc catgtgcagc cgctacgacc ccatccctgt
      301 gtgcacctcc ctttttggag acacttctga tacaacttcc accggccttg ctcagcgctt
      361 agcccggaag accagcaaac aggtgtttgt cagctacaac ctctccaaca cagacagtaa
      421 cttcacgtta ctcgtagaaa acaggattaa ggaagaaatg gagacctttc cggaaaagtt
      481 ctgagcagca gaaggaagag tttgtaacgt gtatataaat gacattgaaa taaacaggtt
      541 gttttttgtc ctcaaaaaaa aaaaaaaaaa aaaaaaa
//
