LOCUS       NM_025604                871 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) assembly chaperone 3
            (Psmg3), transcript variant 1, mRNA.
ACCESSION   NM_025604
VERSION     NM_025604.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Le Tallec,B., Barrault,M.B., Courbeyrette,R., Guerois,R.,
            Marsolier-Kergoat,M.C. and Peyroche,A.
  TITLE     20S proteasome assembly is orchestrated by two distinct pairs of
            chaperones in yeast and in mammals
  JOURNAL   Mol Cell 27 (4), 660-674 (2007)
   PUBMED   17707236
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BE848654.1 and AK012616.1.
            
            On Oct 13, 2017 this sequence version replaced NM_025604.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058692.1, C89433.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164141, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               BE848654.1         1-139
            140-871             AK012616.1         90-821
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 78.81 cM"
     gene            1..871
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /note="proteasome (prosome, macropain) assembly chaperone
                     3"
                     /db_xref="GeneID:66506"
                     /db_xref="MGI:MGI:1913756"
     exon            1..173
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /inference="alignment:Splign:2.1.0"
     exon            174..410
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..563
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /note="PAC-3; mPAC3; proteasome chaperone homolog 3"
                     /codon_start=1
                     /product="proteasome assembly chaperone 3"
                     /protein_id="NP_079880.1"
                     /db_xref="CCDS:CCDS19815.1"
                     /db_xref="GeneID:66506"
                     /db_xref="MGI:MGI:1913756"
                     /translation="MEDKPLVVSKQKTEVVCGVPTQVVCTAFSSHILVVVTQFGKMGT
                     LVSLEPSNVANDISKPVLTTRVLLGQDEPLIHVFAKNLVAFVSQEAGNRAVLLAMAVK
                     DKSMERLKALKEVIRLCQVW"
     exon            411..871
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      857..862
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /note="hexamer: AATAAA"
     polyA_site      871
                     /gene="Psmg3"
                     /gene_synonym="1810042K04Rik; 4930403H09Rik; Pba3"
                     /note="major polyA site"
ORIGIN      
        1 ggaaccggaa gttctcgccg ggacttctgc taaaccattg ctggcttagt tgctccctga
       61 aaccgctttc tggcgctgct ggtggggtga gcgctggttg ccgagggttt cggtcccaac
      121 tgctgtcagt agtgatccag ccatccccag tcctgcgccg tcggggctcc ccgcctccgc
      181 tgaagaacgg gaccatggaa gacaaaccac tggtagtatc taaacagaag acagaagtgg
      241 tgtgcggtgt gcccacccag gtggtctgca cggccttcag cagccacatc ctagttgtgg
      301 tgacccagtt cgggaagatg ggtacgctag tgtccttgga gcccagcaat gtggccaatg
      361 acatcagcaa gccagtgctc accacgagag tcctcctcgg gcaggacgag cctctcatcc
      421 atgtctttgc aaagaacctg gtagcatttg tgtcgcaaga agcaggaaac agagccgtcc
      481 tgctggccat ggctgtgaaa gacaagagca tggagaggct caaggcattg aaggaagtga
      541 tccggctgtg ccaggtgtgg tgacctgccg ttagcagtgc cagacacaga cgtatggacg
      601 ctcggtgagc ggggcctttg agacccatct ttccagcgcc aggagagagc tcattccagg
      661 gcctttagtc ctcaaagctg gaaacagcac tcaagtctca gggactctcc ctgcgtggct
      721 actgtgttct gccttgggca ctggagcggg gctgggctgc agcagctgca tccactgagt
      781 ggaaatgagc ggccggttat gaggacaagt aatcctgggt gtgcaggagc acttgtggga
      841 agattttttt attaaaaata aatctaaagt a
//
