LOCUS       NM_028221               1812 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus proteasome activator subunit 3 interacting protein 1
            (Psme3ip1), transcript variant 1, mRNA.
ACCESSION   NM_028221
VERSION     NM_028221.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1812)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1812)
  AUTHORS   Gao,X., Wang,Q., Wang,Y., Liu,J., Liu,S., Liu,J., Zhou,X., Zhou,L.,
            Chen,H., Pan,L., Chen,J., Wang,D., Zhang,Q., Shen,S., Xiao,Y.,
            Wu,Z., Cheng,Y., Chen,G., Kubra,S., Qin,J., Huang,L., Zhang,P.,
            Wang,C., Moses,R.E., Lonard,D.M., Malley,B.W.O., Fares,F.,
            Zhang,B., Li,X., Li,L. and Xiao,J.
  TITLE     The REGgamma inhibitor NIP30 increases sensitivity to chemotherapy
            in p53-deficient tumor cells
  JOURNAL   Nat Commun 11 (1), 3904 (2020)
   PUBMED   32764536
  REMARK    GeneRIF: The REGgamma inhibitor NIP30 increases sensitivity to
            chemotherapy in p53-deficient tumor cells.
            Erratum:[Nat Commun. 2020 Sep 23;11(1):4888. doi:
            10.1038/s41467-020-18767-0.. PMID: 32968062]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1812)
  AUTHORS   Waddell,D.S., Duffin,P.J., Haddock,A.N., Triplett,V.E.,
            Saredy,J.J., Kakareka,K.M. and Eldredge,J.T.
  TITLE     Isolation, expression analysis and characterization of
            NEFA-interacting nuclear protein 30 and RING finger and SPRY domain
            containing 1 in skeletal muscle
  JOURNAL   Gene 576 (1 Pt 2), 319-332 (2016)
   PUBMED   26497270
  REMARK    GeneRIF: Nip30 is expressed in skeletal muscle.Nip30 and Rspry1
            common promoter region contains a conserved E-box element. Nip30
            localizes to the nucleus.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY245102.1, AK050704.1 and BC016088.1.
            
            On Jul 26, 2008 this sequence version replaced NM_028221.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027060.1, BC040818.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                BY245102.1         2-67
            67-1395             AK050704.1         2-1330
            1396-1812           BC016088.1         1136-1552
FEATURES             Location/Qualifiers
     source          1..1812
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 46.58 cM"
     gene            1..1812
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /note="proteasome activator subunit 3 interacting protein
                     1"
                     /db_xref="GeneID:102122"
                     /db_xref="MGI:MGI:1919637"
     exon            1..230
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     exon            231..327
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     exon            328..465
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     CDS             339..1103
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /note="isoform a is encoded by transcript variant 1;
                     NEFA-interacting nuclear protein NIP30; protein FAM192A;
                     PA28G-interacting protein; family with sequence similarity
                     192, member A; PSME3-interacting protein"
                     /codon_start=1
                     /product="PSME3-interacting protein isoform a"
                     /protein_id="NP_082497.2"
                     /db_xref="CCDS:CCDS40439.1"
                     /db_xref="GeneID:102122"
                     /db_xref="MGI:MGI:1919637"
                     /translation="MDGEDDSNLVIKKRFVSEAELDERRKRRQEEWEKVRKPEDPKEC
                     PEEAYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEK
                     QRREEELEELKEYRSNLNKVGISAENKEVEKKLAVKPIETKNKFSQAKLLAGAVKHKS
                     SESGNSVKRLKPDPDPDDKAQEAPSCMSLGSSSLSGPPSIHCPSAAVCIGILPGLGAY
                     SGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP"
     exon            466..564
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     exon            565..686
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     exon            687..817
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     exon            818..882
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1800
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1773..1778
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /note="hexamer: AATAAA"
     polyA_site      1800
                     /gene="Psme3ip1"
                     /gene_synonym="1700001O11Rik; 2310065K24Rik; Fam192a;
                     Nip30"
                     /note="major polyA site"
ORIGIN      
        1 gattggacta tgccgccgga agcggggtgg aaatgtgttg tggctgtaag gaacaggaag
       61 ccccgaaggg tcaaaaggaa tacaatagcg aagtgtgttt tcttccttta agccgtcgtt
      121 cttttcttgg tttcttttct agttttttaa gagcgagagt ggccttggcg gcgacggttt
      181 acggtaggcg ccgcggaggt gagggcggct cgcctcccgc gctctcgtag atctgccacc
      241 tccctccttc atagacggga cttgactgct aaagcgcctt gagtacctga gagtctccat
      301 tagaatctgc tttggaagca agaacagact gtaccattat ggatggagag gacgatagta
      361 accttgtcat caaaaagagg tttgtgtctg aggcagagct agatgagcgg cgcaaaagga
      421 ggcaagaaga atgggagaaa gtgcgaaaac cagaagaccc aaaagaatgt ccagaggagg
      481 cgtatgaccc tcggtctctg tacgaacggc tgcaggaaca gaaagacagg aagcagcagg
      541 agtatgagga gcaattcaaa ttcaaaaaca tggtaagagg gttagacgaa gatgagacca
      601 acttccttga tgaggtttct cggcagcagg agctgataga gaagcagcgg cgagaagaag
      661 aactagagga actgaaggag tacagaagta atctcaacaa ggttggaatt tctgcagaaa
      721 ataaagaagt agagaagaag ctggccgtga aacccataga aaccaagaac aagttctccc
      781 aggcaaagct gttggcagga gctgtgaaac ataagagctc agagagtggc aatagtgtga
      841 agagactgaa accagacccc gacccagatg acaaggctca agaggccccg tcctgcatgt
      901 ctcttggaag ctcttctctg agcggacctc cctccatcca ctgcccgtcg gctgctgtgt
      961 gcatcggcat cctccctggc ttgggcgcct actctgggag cagtgactcc gaatccagtt
     1021 cagacagtga aggcaccatc aatgctacag ggaagatcgt ctcctccatc ttccgaacca
     1081 acaccttcct cgaggcaccc tagctcctga tattaccaca gggagcatct cagagggttg
     1141 gatgccagtt ctgcctcggc atcacctccc tcagaaaact tactcacctg cttcctgtgc
     1201 acatgtgaca ttttaaccta actcagaaat gtgtctcagt ccacttgtgg ctcaaactcg
     1261 gcttgatttc tctttatact cctgtgcaga tgaccaaacc tgtcccattg atatgaggag
     1321 tcggggttca ggcttgtctc agaaatgtca cggacagtgc aaggacaggc agcagctggc
     1381 ctgccagggt ttggtgtacc ttgttgctgt cttgtttatc tccttaccta gcagcacagg
     1441 aagcaagggc agcgttagct tcatatgttg ttgtagatga atgggtttct tggttctacc
     1501 atgttgtgtg tgggcataga gaaaggggct gaccagctgg tgacatggag ctgtccccta
     1561 gaactaaccc ttcctgggtg ttgtgtgact taagtaaaaa tctcaagcct cacccacaag
     1621 gctgtgagcc aacgacagcc cttgagcaga gactcttcca tgtcctcccc tctccatcca
     1681 gcctgaggag gtaggaagga gctgaccacg agaacatgac catcctctgc ccaccttctc
     1741 tctctgaaaa aatgttttga ttttgttttt gaaataaaag atttagttta agattctaaa
     1801 aaaaaaaaaa aa
//
