LOCUS       NM_026545               1529 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) 26S subunit,
            non-ATPase, 8 (Psmd8), mRNA.
ACCESSION   NM_026545 XM_001001968 XM_001001977 XM_001001989 XM_001002004
            XM_001002011
VERSION     NM_026545.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Gresakova,V., Novosadova,V., Prochazkova,M., Prochazka,J. and
            Sedlacek,R.
  TITLE     Dual role of Fam208a during zygotic cleavage and early embryonic
            development
  JOURNAL   Exp Cell Res 406 (2), 112723 (2021)
   PUBMED   34216590
REFERENCE   2  (bases 1 to 1529)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1529)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   4  (bases 1 to 1529)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   5  (bases 1 to 1529)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF732286.1, AK003436.1 and CD774979.1.
            
            On Sep 1, 2007 this sequence version replaced NM_026545.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.57016.1, AK153329.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               CF732286.1         1-159
            160-1169            AK003436.1         1-1010
            1170-1529           CD774979.1         1-360               c
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.94 cM"
     gene            1..1529
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 8"
                     /db_xref="GeneID:57296"
                     /db_xref="MGI:MGI:1888669"
     exon            1..397
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1090
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="proteasome 26S non-ATPase subunit 8; 26S proteasome
                     regulatory subunit S14; 26S proteasome regulatory subunit
                     RPN12"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 8"
                     /protein_id="NP_080821.3"
                     /db_xref="CCDS:CCDS52169.1"
                     /db_xref="GeneID:57296"
                     /db_xref="MGI:MGI:1888669"
                     /translation="MFIKGRAAKTPRGEPRRSSRGGRKLAVVAPPPVLGSTSRPHFRR
                     ESIARRRCRKSGRRLAASRKMAATAATVNGSTTVSSSGPAATSVGILQAAAGMYEQLK
                     DEWNRKNPNLSKCGEELGRLKLVLLELNFLPTTGTKLTKQQLILARDILEIGAQWSIL
                     CKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERL
                     PAKDIQTNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAG
                     CIEKAYEKILFAEATRILFFSTPKKMTDYAKKRGWVLGPNNYYSFASQQQKPEDSTIP
                     STELAKQVIEYARQLEMIV"
     exon            398..470
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            471..573
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            574..739
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            740..840
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            841..952
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1513
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1149..1154
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1171
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="major polyA site"
     regulatory      1426..1431
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1446
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="major polyA site"
     regulatory      1493..1498
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1513
                     /gene="Psmd8"
                     /gene_synonym="6720456J22Rik"
                     /note="major polyA site"
ORIGIN      
        1 tgaatgacag cagaggcgga gctgcggcat gttcattaag ggtcgggctg cgaagacacc
       61 ccgaggagag ccgcggcgct cctcccgcgg ggggcggaaa ctggcagtgg tagctccgcc
      121 tccagttttg ggctccacct cccggcctca tttccgccgg gagtccattg cccggcgtcg
      181 ctgccgtaag tcgggtcggc ggcttgccgc atcacggaag atggcggcca cagcggctac
      241 ggtgaacggg tcgaccaccg tctcgagctc cggacccgcg gccacctcgg tcgggatcct
      301 gcaggcagcg gccggcatgt acgagcaact caaggacgag tggaaccgga agaacccgaa
      361 ccttagtaaa tgtggagaag aactgggccg cctgaagttg gttctgcttg agctcaattt
      421 cctgccaacc acggggacca aactgactaa acagcaactc attctggccc gtgacattct
      481 ggagatcggg gcccagtgga gcatcctgtg caaagacatt ccctccttcg agcgctacat
      541 ggcccaactc aaatgctact actttgatta caaagaacag cttcctgagt cagcctatat
      601 gcaccagctc ctgggcctca atctcctctt cctgctatct cagaaccgag tggctgagtt
      661 ccacacagaa ttagaacgat tacctgccaa ggacatccag accaatgtct acatcaaaca
      721 ccctgtttcc ctcgagcaat acctcatgga gggtagctac aacaaggtat tcctggctaa
      781 ggggaacatc cctgccgaaa gctacacctt cttcattgac atcctgctgg ataccatcag
      841 ggatgaaatc gcaggatgca ttgagaaggc ctatgagaaa atcctttttg ctgaggctac
      901 ccggatcctc ttcttcagca cacccaaaaa gatgacagac tatgccaaga agcgaggttg
      961 ggtgctgggc cctaacaact actacagctt tgccagccag cagcagaagc cagaagacag
     1021 caccatcccc tctactgaac tggccaaaca agtcatcgag tatgcccggc agctggagat
     1081 gattgtctga ggcttgacca gggcggtgga tatggctagt ccaacaaacc cagtataggc
     1141 tggccttcaa taaaggcaga ttaacctcta atgggcccga gtctccccag tgtgatggtg
     1201 gagataaatt gctcctggag atttgggagt ttgcgaagcg tttcccagtt gtcattgctc
     1261 tgggttttaa gtatagatgc ccggtggccc acaggagagc acaggcccag actgagggac
     1321 tcttctatcc agctgtggat gcgttttggt gttgggccag ggactagatt ttttttcccc
     1381 agtgaagcac cgtgtgtctc agttttaaaa aaatgttggc cgtggattaa ataattttta
     1441 aaatgagaca tgaaactgac tttgtctatg ggctaccatt tgagccctct gtaataaatg
     1501 gtatgaatcc tgaaaaaaaa aaaaaaaaa
//
