LOCUS       NM_010817               1616 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) 26S subunit,
            non-ATPase, 7 (Psmd7), mRNA.
ACCESSION   NM_010817
VERSION     NM_010817.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1616)
  AUTHORS   Wang,J., Liu,R., Mo,H., Xiao,X., Xu,Q. and Zhao,W.
  TITLE     Deubiquitinase PSMD7 promotes the proliferation, invasion, and
            cisplatin resistance of gastric cancer cells by stabilizing RAD23B
  JOURNAL   Int J Biol Sci 17 (13), 3331-3342 (2021)
   PUBMED   34512150
  REMARK    GeneRIF: Deubiquitinase PSMD7 promotes the proliferation, invasion,
            and cisplatin resistance of gastric cancer cells by stabilizing
            RAD23B.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1616)
  AUTHORS   Hamazaki,J., Hirayama,S. and Murata,S.
  TITLE     Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated
            Proteins and Cellular Homeostasis
  JOURNAL   PLoS Genet 11 (7), e1005401 (2015)
   PUBMED   26222436
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1616)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   4  (bases 1 to 1616)
  AUTHORS   Liang,G., Li,Q., Tang,Y., Kokame,K., Kikuchi,T., Wu,G. and
            Chen,X.Z.
  TITLE     Polycystin-2 is regulated by endoplasmic reticulum-associated
            degradation
  JOURNAL   Hum Mol Genet 17 (8), 1109-1119 (2008)
   PUBMED   18178578
REFERENCE   5  (bases 1 to 1616)
  AUTHORS   Stanhill,A., Haynes,C.M., Zhang,Y., Min,G., Steele,M.C.,
            Kalinina,J., Martinez,E., Pickart,C.M., Kong,X.P. and Ron,D.
  TITLE     An arsenite-inducible 19S regulatory particle-associated protein
            adapts proteasomes to proteotoxicity
  JOURNAL   Mol Cell 23 (6), 875-885 (2006)
   PUBMED   16973439
REFERENCE   6  (bases 1 to 1616)
  AUTHORS   Tsurumi,C., DeMartino,G.N., Slaughter,C.A., Shimbara,N. and
            Tanaka,K.
  TITLE     cDNA cloning of p40, a regulatory subunit of the human 26S
            proteasome, and a homolog of the Mov-34 gene product
  JOURNAL   Biochem Biophys Res Commun 210 (2), 600-608 (1995)
   PUBMED   7755639
REFERENCE   7  (bases 1 to 1616)
  AUTHORS   Dubiel,W., Ferrell,K., Dumdey,R., Standera,S., Prehn,S. and
            Rechsteiner,M.
  TITLE     Molecular cloning and expression of subunit 12: a non-MCP and
            non-ATPase subunit of the 26 S protease
  JOURNAL   FEBS Lett 363 (1-2), 97-100 (1995)
   PUBMED   7729561
REFERENCE   8  (bases 1 to 1616)
  AUTHORS   Gridley,T., Jaenisch,R. and Gendron-Maguire,M.
  TITLE     The murine Mov-34 gene: full-length cDNA and genomic organization
  JOURNAL   Genomics 11 (3), 501-507 (1991)
   PUBMED   1837787
REFERENCE   9  (bases 1 to 1616)
  AUTHORS   Gridley,T., Gray,D.A., Orr-Weaver,T., Soriano,P., Barton,D.E.,
            Francke,U. and Jaenisch,R.
  TITLE     Molecular analysis of the Mov 34 mutation: transcript disrupted by
            proviral integration in mice is conserved in Drosophila
  JOURNAL   Development 109 (1), 235-242 (1990)
   PUBMED   2209467
REFERENCE   10 (bases 1 to 1616)
  AUTHORS   Soriano,P., Gridley,T. and Jaenisch,R.
  TITLE     Retroviruses and insertional mutagenesis in mice: proviral
            integration at the Mov 34 locus leads to early embryonic death
  JOURNAL   Genes Dev 1 (4), 366-375 (1987)
   PUBMED   2824282
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134855.5, BC130014.1 and AW492454.1.
            
            On Mar 13, 2010 this sequence version replaced NM_010817.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M64641.1, BC130014.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AC134855.5         79003-79025
            24-1231             BC130014.1         1-1208
            1232-1616           AW492454.1         1-385               c
FEATURES             Location/Qualifiers
     source          1..1616
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 54.38 cM"
     gene            1..1616
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 7"
                     /db_xref="GeneID:17463"
                     /db_xref="MGI:MGI:1351511"
     exon            1..204
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..1096
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /note="proteasome subunit p40; 26S proteasome regulatory
                     subunit S12; 26S proteasome regulatory subunit rpn8"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 7"
                     /protein_id="NP_034947.1"
                     /db_xref="CCDS:CCDS22650.1"
                     /db_xref="GeneID:17463"
                     /db_xref="MGI:MGI:1351511"
                     /translation="MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQ
                     KKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLH
                     KNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTS
                     EIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVASG
                     KLPINHQIIYQLQDVFNLLPDASLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLI
                     NNKIANRDAEKKEGQEKEESKKERKDDKEKEKSDAAKKEEKKEKK"
     exon            205..296
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     exon            297..389
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     exon            390..487
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     exon            488..568
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     exon            569..660
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     exon            661..1600
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1581..1586
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /note="hexamer: ATTAAA"
     polyA_site      1600
                     /gene="Psmd7"
                     /gene_synonym="Mov-34; Mov34"
                     /note="major polyA site"
ORIGIN      
        1 gaagtcgact gtgcagcggc ggtcaaaccg gaaggggagg tgctggggcc tggaggagcg
       61 gcctgtgtcg ctgcggttgc tggtgtttgc gggttgcagg gagccgggcc ggtggtcggg
      121 ctgtgtcgcg atgccggagc tggcggtgca gaaggtggtg gttcaccccc tggtgctgct
      181 cagtgtggtg gatcatttca accgaattgg caaggttgga aaccagaagc gggtagttgg
      241 tgtgcttttg ggatcatggc aaaagaaagt acttgatgta tccaacagtt ttgcagtacc
      301 ttttgatgaa gatgacaaag atgattctgt ctggttttta gaccatgatt atttggaaaa
      361 catgtatggg atgttcaaga aggtcaatgc cagagaaagg atagttgggt ggtaccacac
      421 aggccccaaa ctgcacaaga atgatatcgc catcaatgaa ctcatgaaga gatactgccc
      481 caactcagta ttggtcatta tcgacgtgaa gccaaaggac ctaggacttc ccaccgaagc
      541 ctacatctca gtggaggaag ttcatgacga tgggacgcca acgtcaaaaa cttttgagca
      601 tgtgactagc gagattggag cagaggaggc ggaggaagtc ggagtggagc acttactaag
      661 agacatcaag gacactacag tggggactct ctcccagcgg atcacaaacc aggtccatgg
      721 cttgaaggga ctgaactcca agctcctgga tatcaggagc tacctggaga aggtagccag
      781 cggcaagctg cccatcaacc accagatcat ataccagctg caggacgtct tcaacctgct
      841 gccggacgcc agcctgcagg agtttgtcaa ggccttctac ctgaagacca atgaccagat
      901 ggtggtggtg tacctggcct cgctgatccg ctctgtggtc gccttgcata acctcatcaa
      961 caacaagatt gccaaccggg atgccgagaa gaaggaggga caggaaaagg aggagagcaa
     1021 gaaggagaga aaagacgaca aagagaagga gaagagcgac gcagcgaaga aagaagagaa
     1081 aaaggagaaa aagtaaatgg tgtagctttt ttaattagta aattaaaatc ttataaccat
     1141 aactccgtgt gccactagga gggtcctttg tcacattcag tgcttgtgga caagcgctct
     1201 gccctggtca cccttgctgt ggcattgtgg agatgagtgg acaaaaggac ggatctcagc
     1261 cctacgatac agcttcagtt gcatgagttg ggggtgtggt ggctcaggtg tccgacttca
     1321 tgaggagaac aacctagcct tgggcactct tccttttatc cttgaaaggg attttttttc
     1381 ctatcttaca agatccatgg gatctgttgg ttgtaatttt cataattgct aaatggaatt
     1441 catggatccc atacaatgcc gcccaacact tgagcttgga cccttgtgaa cttttgagac
     1501 cacaccacct tttggacctg taactagcat tcttagggct tggggtccaa ggccatgtat
     1561 tgtttacctt caaagataca attaaatggc ttggttttta aaaaaaaaaa aaaaaa
//
