LOCUS       NM_025550               1337 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) 26S subunit,
            non-ATPase, 6 (Psmd6), mRNA.
ACCESSION   NM_025550
VERSION     NM_025550.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Hao,L., Vassena,R., Wu,G., Han,Z., Cheng,Y., Latham,K.E. and
            Sapienza,C.
  TITLE     The unfolded protein response contributes to preimplantation mouse
            embryo death in the DDK syndrome
  JOURNAL   Biol Reprod 80 (5), 944-953 (2009)
   PUBMED   19129515
REFERENCE   2  (bases 1 to 1337)
  AUTHORS   Shen,F., Lin,Q., Gu,Y., Childress,C. and Yang,W.
  TITLE     Activated Cdc42-associated kinase 1 is a component of EGF receptor
            signaling complex and regulates EGF receptor degradation
  JOURNAL   Mol Biol Cell 18 (3), 732-742 (2007)
   PUBMED   17182860
REFERENCE   3  (bases 1 to 1337)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   4  (bases 1 to 1337)
  AUTHORS   Ren,S., Smith,M.J., Louro,I.D., McKie-Bell,P., Bani,M.R.,
            Wagner,M., Zochodne,B., Redden,D.T., Grizzle,W.E., Wang,Nd.,
            Smith,D.I., Herbst,R.A., Bardenheuer,W., Opalka,B., Schutte,J.,
            Trent,J.M., Ben-David,Y. and Ruppert,J.M.
  TITLE     The p44S10 locus, encoding a subunit of the proteasome regulatory
            particle, is amplified during progression of cutaneous malignant
            melanoma
  JOURNAL   Oncogene 19 (11), 1419-1427 (2000)
   PUBMED   10723133
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116479.14.
            
            On Jan 25, 2019 this sequence version replaced NM_025550.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006869.1, AK010287.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-207               AC116479.14        2048-2254
            208-413             AC116479.14        2801-3006
            414-559             AC116479.14        6023-6168
            560-779             AC116479.14        6390-6609
            780-888             AC116479.14        6737-6845
            889-1057            AC116479.14        8702-8870
            1058-1135           AC116479.14        10390-10467
            1136-1337           AC116479.14        10607-10808
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 7.08 cM"
     gene            1..1337
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 6"
                     /db_xref="GeneID:66413"
                     /db_xref="MGI:MGI:1913663"
     exon            1..207
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..1232
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /note="proteasome, 26S, non-ATPase regulatory subunit 6;
                     p42A; 26S proteasome regulatory subunit S10; 26S
                     proteasome regulatory subunit RPN7"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 6"
                     /protein_id="NP_079826.2"
                     /db_xref="CCDS:CCDS26824.1"
                     /db_xref="GeneID:66413"
                     /db_xref="MGI:MGI:1913663"
                     /translation="MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVREELMAA
                     VRENNMAPYYEALCKSLDWQMDVDLLSKMKKANEEELKRLDEELEDAEKNLGESEIRD
                     AMMAKAEYLCQIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRN
                     TEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKT
                     FVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLA
                     IVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVDFIDQEL
                     SRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM"
     exon            208..413
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            414..559
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            560..779
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            780..888
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            889..1057
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1135
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1337
                     /gene="Psmd6"
                     /gene_synonym="2400006A19Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcttccgc tggtggccca gggctgtgct tggttctgtc agccggctcc tgtgctgtag
       61 ccatgccgct agaaaaccta gaagaagagg gactgcccaa gaaccccgac ctgcgcatcg
      121 cgcagctgcg gtttctgctt agcctgccgg agcaccgcgg ggacgcggcg gtgcgcgagg
      181 agttgatggc ggccgtccgg gaaaacaata tggctcctta ttatgaagcc ttgtgtaaat
      241 ccctcgactg gcagatggac gtggatctcc tgagtaaaat gaagaaagca aacgaagaag
      301 agttgaaacg tttggatgag gagctggagg atgcagagaa gaatctggga gaaagtgaaa
      361 ttcgagatgc aatgatggca aaagcagagt acctctgtca gataggtgac aaggaaggag
      421 ctttgacagc ttttcgcaag acatacgata agactgtggc cctgggtcac cgcctggata
      481 ttgtattcta tctcctaagg atcggactct tttatatgga taatgacctc attactcgaa
      541 acacagaaaa ggccaaaagc ctgatagagg aaggcggaga ctgggacagg cgaaacaggc
      601 tgaaagtgta ccagggctta tattgtgtgg ctatccgtga cttcaaacag gcagcagagc
      661 tctttctcga cactgtttct acgtttacat cgtatgagct catggattac aagacatttg
      721 tgacttacac tgtttacgtc agtatgatcg ccttagaaag gccggacctc agggaaaagg
      781 tcattaaagg ggcagagatc cttgaagtgt tgcacagtct tccagcagtt cggcagtatc
      841 tgttttctct ctatgaatgc cgttattcag tttttttcca atcattagca atcgtggaac
      901 aggaaatgaa aaaggattgg ctttttgcgc ctcattaccg atactatgta agagaaatga
      961 gaatccatgc gtacagccag ctgctggaat catataggtc attaaccctc ggctatatgg
     1021 cagaagcttt tggtgtgggt gtggacttca ttgaccagga gctgtccagg tttattgctg
     1081 ctggaagact ccactgcaaa attgataaag taaatgaaat cgtggagacc aacagacctg
     1141 atagcaagaa ctggcagtat caagaaacca tcaagaaagg agacttgctg ctaaacaggg
     1201 ttcagaaatt atccagagta attaacatgt aaagccactt ttcaacgtgt tcctttacag
     1261 acgttacttg gaagcttttc taacttcttc actgtgtgcc cacttcaaca gcatcaaata
     1321 aatatgtcat ttgtttc
//
