LOCUS       NM_008949                984 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) 26S subunit, ATPase 3,
            interacting protein (Psmc3ip), mRNA.
ACCESSION   NM_008949
VERSION     NM_008949.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Lin,T., Zhang,Y., Zhang,T., Steckler,R.A. and Yang,X.
  TITLE     Hop2 interacts with the transcription factor CEBPalpha and
            suppresses adipocyte differentiation
  JOURNAL   J Biol Chem 297 (5), 101264 (2021)
   PUBMED   34600885
  REMARK    GeneRIF: Hop2 interacts with the transcription factor CEBPalpha and
            suppresses adipocyte differentiation.
REFERENCE   2  (bases 1 to 984)
  AUTHORS   de la Fuente,R., Pratto,F., Hernandez-Hernandez,A., Manterola,M.,
            Lopez-Jimenez,P., Gomez,R., Viera,A., Parra,M.T., Kouznetsova,A.,
            Camerini-Otero,R.D. and Page,J.
  TITLE     Epigenetic Dysregulation of Mammalian Male Meiosis Caused by
            Interference of Recombination and Synapsis
  JOURNAL   Cells 10 (9), 2311 (2021)
   PUBMED   34571960
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 984)
  AUTHORS   Zhang,Y., Lin,T., Lian,N., Tao,H., Li,C., Li,L. and Yang,X.
  TITLE     Hop2 Interacts with ATF4 to Promote Osteoblast Differentiation
  JOURNAL   J Bone Miner Res 34 (12), 2287-2300 (2019)
   PUBMED   31433867
  REMARK    GeneRIF: Hop2 Interacts with ATF4 to Promote Osteoblast
            Differentiation.
REFERENCE   4  (bases 1 to 984)
  AUTHORS   Brick,K., Thibault-Sennett,S., Smagulova,F., Lam,K.G., Pu,Y.,
            Pratto,F., Camerini-Otero,R.D. and Petukhova,G.V.
  TITLE     Extensive sex differences at the initiation of genetic
            recombination
  JOURNAL   Nature 561 (7723), 338-342 (2018)
   PUBMED   30185906
REFERENCE   5  (bases 1 to 984)
  AUTHORS   Thibault-Sennett,S., Yu,Q., Smagulova,F., Cloutier,J., Brick,K.,
            Camerini-Otero,R.D. and Petukhova,G.V.
  TITLE     Interrogating the Functions of PRDM9 Domains in Meiosis
  JOURNAL   Genetics 209 (2), 475-487 (2018)
   PUBMED   29674518
REFERENCE   6  (bases 1 to 984)
  AUTHORS   Petukhova,G.V., Pezza,R.J., Vanevski,F., Ploquin,M., Masson,J.Y.
            and Camerini-Otero,R.D.
  TITLE     The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in
            meiotic recombination
  JOURNAL   Nat Struct Mol Biol 12 (5), 449-453 (2005)
   PUBMED   15834424
  REMARK    GeneRIF: data reveal an interplay among Hop2, Mnd1 and Rad51 and
            Dmc1 in the formation of the first recombination intermediates
            during meiosis
REFERENCE   7  (bases 1 to 984)
  AUTHORS   Enomoto,R., Kinebuchi,T., Sato,M., Yagi,H., Shibata,T.,
            Kurumizaka,H. and Yokoyama,S.
  TITLE     Positive role of the mammalian TBPIP/HOP2 protein in DMC1-mediated
            homologous pairing
  JOURNAL   J Biol Chem 279 (34), 35263-35272 (2004)
   PUBMED   15192114
  REMARK    GeneRIF: C-terminal basic region of TBPIP/HOP2 is required for
            efficient DNA binding and is also essential for its homologous
            pairing stimulation activity
REFERENCE   8  (bases 1 to 984)
  AUTHORS   Petukhova,G.V., Romanienko,P.J. and Camerini-Otero,R.D.
  TITLE     The Hop2 protein has a direct role in promoting interhomolog
            interactions during mouse meiosis
  JOURNAL   Dev Cell 5 (6), 927-936 (2003)
   PUBMED   14667414
REFERENCE   9  (bases 1 to 984)
  AUTHORS   Ijichi,H., Tanaka,T., Nakamura,T., Yagi,H., Hakuba,A. and Sato,M.
  TITLE     Molecular cloning and characterization of a human homologue of
            TBPIP, a BRCA1 locus-related gene
  JOURNAL   Gene 248 (1-2), 99-107 (2000)
   PUBMED   10806355
REFERENCE   10 (bases 1 to 984)
  AUTHORS   Tanaka,T., Nakamura,T., Takagi,H. and Sato,M.
  TITLE     Molecular cloning and characterization of a novel TBP-1 interacting
            protein (TBPIP):enhancement of TBP-1 action on Tat by TBPIP
  JOURNAL   Biochem Biophys Res Commun 239 (1), 176-181 (1997)
   PUBMED   9345291
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX255926.10, AK133462.1 and BF658859.1.
            
            On Aug 13, 2011 this sequence version replaced NM_008949.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133462.1, BC030169.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                BX255926.10        28075-28107         c
            34-297              AK133462.1         2-265
            298-396             BX255926.10        26353-26451         c
            397-970             AK133462.1         365-938
            971-984             BF658859.1         1-14                c
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 64.19 cM"
     gene            1..984
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /note="proteasome (prosome, macropain) 26S subunit, ATPase
                     3, interacting protein"
                     /db_xref="GeneID:19183"
                     /db_xref="MGI:MGI:1098610"
     exon            1..93
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            94..194
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            195..284
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            285..396
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            397..542
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            543..596
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            597..656
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     exon            657..972
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /inference="alignment:Splign:2.1.0"
     regulatory      909..914
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /note="hexamer: AAGAAA"
     polyA_site      914
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /note="major polyA site"
     regulatory      935..940
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
                     /note="hexamer: AATATA"
     polyA_site      972
                     /gene="Psmc3ip"
                     /gene_synonym="GT198; HOP2; Tbpip"
ORIGIN      
        1 gaggcgtttc ccggagcaac cgaccagtcc agctctcgag tttggtggcg ggaaaggcca
       61 tgagtaaaag ccgggccgag gctgcggctg gagcccccgg gatcatcctg aggtacctgc
      121 aagaacaaaa ccggccctac agcgcccagg acgtgttcgg aaacctacag aaggaacatg
      181 gactgggcaa ggcggcggta gtgaaggcgc tggatcagct ggcccaggaa ggcaagatca
      241 aagagaagac ctacggcaag cagaaaattt attttgccga tcagaaccag tttgacacag
      301 tgagtgatgc ggacctccac ggcctggatg ccagtatcgt ggccctcact gccaaggtgc
      361 agagcttaca gcagagctgc cgacacatgg aggccgagct gaaggaatta acaagtgcgc
      421 tgaccactcc tgagatgcag aaagagattc aggagttaaa gaaggagtgt gctcaataca
      481 cagagagact gaagaacatc aaagcagcta ccaaccatgt cactccagaa gagaaggaga
      541 aggtgtacag agacagacag aagtactgta aagagtggag gaagcggaag aggatgacca
      601 cagagctgtg tgatgcgatc cttgaaggct accccaagag caagaagcag ttctttgagg
      661 aagttggaat agagacagat gaagatcata atgttttgct ccccgacccc tgaggggccc
      721 ttggtggagg tgggaacaga gcgtcctgcg ctggccacct tacttagtgg cctttttatt
      781 cttgctgttc tccacctttg agcagtggac ggagcacaaa gccatagtgt tagatagagg
      841 ctggtgatca gaaaggacgg tcatgtccgt tttgtacagg cctcaacaag gacttaaaac
      901 aatcctaaaa gaaagtattt gtaatattta ttgtaatata atttgatata aaaatactta
      961 atttcctctg gaaaaaaaaa aaaa
//
