LOCUS       NM_011971                731 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Mus musculus proteasome (prosome, macropain) subunit, beta type 3
            (Psmb3), mRNA.
ACCESSION   NM_011971
VERSION     NM_011971.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Dai,N., Zhao,L., Wrighting,D., Kramer,D., Majithia,A., Wang,Y.,
            Cracan,V., Borges-Rivera,D., Mootha,V.K., Nahrendorf,M.,
            Thorburn,D.R., Minichiello,L., Altshuler,D. and Avruch,J.
  TITLE     IGF2BP2/IMP2-Deficient mice resist obesity through enhanced
            translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial
            proteins
  JOURNAL   Cell Metab 21 (4), 609-621 (2015)
   PUBMED   25863250
REFERENCE   2  (bases 1 to 731)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   3  (bases 1 to 731)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   4  (bases 1 to 731)
  AUTHORS   McClive,P.J., Hurley,T.M., Sarraj,M.A., van den Bergen,J.A. and
            Sinclair,A.H.
  TITLE     Subtractive hybridisation screen identifies sexually dimorphic gene
            expression in the embryonic mouse gonad
  JOURNAL   Genesis 37 (2), 84-90 (2003)
   PUBMED   14595844
REFERENCE   5  (bases 1 to 731)
  AUTHORS   Kleiter,N., Artner,I., Gmachl,N., Ghaffari-Tabrizi,N. and
            Kratochwil,K.
  TITLE     Mutagenic transgene insertion into a region of high gene density
            and multiple linkage disruptions on mouse chromosome 11
  JOURNAL   Cytogenet Genome Res 97 (1-2), 100-105 (2002)
   PUBMED   12438746
  REMARK    GeneRIF: located within a 185-kb contig surrounding a transgene on
            chromosome 11
REFERENCE   6  (bases 1 to 731)
  AUTHORS   Elenich,L.A., Nandi,D., Kent,A.E., McCluskey,T.S., Cruz,M.,
            Iyer,M.N., Woodward,E.C., Conn,C.W., Ochoa,A.L., Ginsburg,D.B. and
            Monaco,J.J.
  TITLE     The complete primary structure of mouse 20S proteasomes
  JOURNAL   Immunogenetics 49 (10), 835-842 (1999)
   PUBMED   10436176
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL596123.32.
            
            On Apr 28, 2007 this sequence version replaced NM_011971.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK153162.1, BG065793.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AL596123.32        145146-145202
            58-242              AL596123.32        145500-145684
            243-350             AL596123.32        148510-148617
            351-528             AL596123.32        152814-152991
            529-623             AL596123.32        154149-154243
            624-731             AL596123.32        155105-155212
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 61.07 cM"
     gene            1..731
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /note="proteasome (prosome, macropain) subunit, beta type
                     3"
                     /db_xref="GeneID:26446"
                     /db_xref="MGI:MGI:1347014"
     exon            1..57
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..672
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /EC_number="3.4.25.1"
                     /note="proteasome chain 13; proteasome theta chain;
                     proteasome component C10-II; beta-3; proteasome subunit
                     beta-3"
                     /codon_start=1
                     /product="proteasome subunit beta type-3"
                     /protein_id="NP_036101.1"
                     /db_xref="CCDS:CCDS25328.1"
                     /db_xref="GeneID:26446"
                     /db_xref="MGI:MGI:1347014"
                     /translation="MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFP
                     MGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGP
                     YYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDP
                     EHLFETISQAMLNAVDRDAVSGMGVIVHVIEKDKITTRTLKARMD"
     exon            58..242
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /inference="alignment:Splign:2.1.0"
     exon            243..350
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /inference="alignment:Splign:2.1.0"
     exon            351..528
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /inference="alignment:Splign:2.1.0"
     exon            529..623
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /inference="alignment:Splign:2.1.0"
     exon            624..731
                     /gene="Psmb3"
                     /gene_synonym="C10-II"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagccggtt tgcaggcaac gctgtgggga tcgggcttcc actccagcgc aatcatgtct
       61 attatgtcct ataatggagg ggccgtcatg gccatgaagg gaaagaactg tgtggccatc
      121 gctgcagaca gacgtttcgg gatccaggcc cagatggtga ccacggactt ccagaagatc
      181 tttcccatgg gtgacaggct ctacataggc ctggccggcc tggccactga cgtccagaca
      241 gttgcccagc gtctcaagtt ccgactgaac ttgtatgagc tgaaagaagg tcgacagatc
      301 aagccttaca ccctcatgag catggtggcc aacctcctgt atgagaagcg gttcggtccc
      361 tactacacag agcctgtcat tgctggcctg gacccgaaga ccttcaagcc cttcatttgc
      421 tctctggacc tcattggctg tcccatggtg actgatgact ttgtagtcag tggtacctgc
      481 tccgaacaaa tgtatgggat gtgtgagtct ctctgggagc ccaacatgga tccagaacac
      541 ctgtttgaaa ccatttctca ggccatgctg aacgcggtgg accgggatgc cgtgtcgggc
      601 atgggcgtca tcgtccacgt cattgagaaa gacaagatca ccaccaggac gctgaaggcc
      661 cggatggact aacctgtgct ctggtcccat ctcccttttg tttttctttt taataaaatt
      721 gcctttcttt c
//
