LOCUS       NM_011967               1217 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Mus musculus proteasome subunit alpha 5 (Psma5), mRNA.
ACCESSION   NM_011967
VERSION     NM_011967.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1217)
  AUTHORS   Raja,R., Dumontier,E., Phen,A. and Cloutier,J.F.
  TITLE     Insertion of a neomycin selection cassette in the Amigo1 locus
            alters gene expression in the olfactory epithelium leading to
            region-specific defects in olfactory receptor neuron development
  JOURNAL   Genesis 62 (2), e23594 (2024)
   PUBMED   38590146
REFERENCE   2  (bases 1 to 1217)
  AUTHORS   Rios,J.J., Denton,K., Yu,H., Manickam,K., Garner,S., Russell,J.,
            Ludwig,S., Rosenfeld,J.A., Liu,P., Munch,J., Sucato,D.J.,
            Beutler,B. and Wise,C.A.
  TITLE     Saturation mutagenesis defines novel mouse models of severe spine
            deformity
  JOURNAL   Dis Model Mech 14 (6) (2021)
   PUBMED   34142127
REFERENCE   3  (bases 1 to 1217)
  AUTHORS   Sasaki,K., Hamazaki,J., Koike,M., Hirano,Y., Komatsu,M.,
            Uchiyama,Y., Tanaka,K. and Murata,S.
  TITLE     PAC1 gene knockout reveals an essential role of chaperone-mediated
            20S proteasome biogenesis and latent 20S proteasomes in cellular
            homeostasis
  JOURNAL   Mol Cell Biol 30 (15), 3864-3874 (2010)
   PUBMED   20498273
REFERENCE   4  (bases 1 to 1217)
  AUTHORS   Murata,S., Sasaki,K., Kishimoto,T., Niwa,S., Hayashi,H.,
            Takahama,Y. and Tanaka,K.
  TITLE     Regulation of CD8+ T cell development by thymus-specific
            proteasomes
  JOURNAL   Science 316 (5829), 1349-1353 (2007)
   PUBMED   17540904
REFERENCE   5  (bases 1 to 1217)
  AUTHORS   Gomes,A.V., Zong,C., Edmondson,R.D., Li,X., Stefani,E., Zhang,J.,
            Jones,R.C., Thyparambil,S., Wang,G.W., Qiao,X., Bardag-Gorce,F. and
            Ping,P.
  TITLE     Mapping the murine cardiac 26S proteasome complexes
  JOURNAL   Circ Res 99 (4), 362-371 (2006)
   PUBMED   16857966
REFERENCE   6  (bases 1 to 1217)
  AUTHORS   Elenich,L.A., Nandi,D., Kent,A.E., McCluskey,T.S., Cruz,M.,
            Iyer,M.N., Woodward,E.C., Conn,C.W., Ochoa,A.L., Ginsburg,D.B. and
            Monaco,J.J.
  TITLE     The complete primary structure of mouse 20S proteasomes
  JOURNAL   Immunogenetics 49 (10), 835-842 (1999)
   PUBMED   10436176
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK143468.1.
            
            On Apr 6, 2007 this sequence version replaced NM_011967.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143468.1, AK160741.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1217              AK143468.1         3-1219
FEATURES             Location/Qualifiers
     source          1..1217
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 46.89 cM"
     gene            1..1217
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /note="proteasome subunit alpha 5"
                     /db_xref="GeneID:26442"
                     /db_xref="MGI:MGI:1347009"
     exon            1..380
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..1077
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /EC_number="3.4.25.1"
                     /note="macropain zeta chain; proteasome zeta chain;
                     multicatalytic endopeptidase complex zeta chain;
                     proteasome (prosome, macropain) subunit, alpha type 5;
                     alpha-5"
                     /codon_start=1
                     /product="proteasome subunit alpha type-5"
                     /protein_id="NP_036097.1"
                     /db_xref="CCDS:CCDS17755.1"
                     /db_xref="GeneID:26442"
                     /db_xref="MGI:MGI:1347009"
                     /translation="MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSE
                     GVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFT
                     YNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSG
                     TFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELA
                     TVQPGQNFHMFTKEELEEVIKDI"
     exon            381..447
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            448..574
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            575..642
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            643..750
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            751..809
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            810..912
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            913..999
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1217
                     /gene="Psma5"
                     /gene_synonym="ZETA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagcgcggc gtgctcactc ctcgacgacg aggttcactc tcaccggttg cctcgagtcc
       61 cagcgcccgt agcaaccaag ggtgacggaa agcggaagtg ctctctagtt ccgcctccct
      121 gttaacccag gtccggtgaa gaagcttgtc aagtccaatc atcgcggcga gaatatcaat
      181 cagccaataa aagggaagca cgggagggcg ggctaaaaag gtcgcgtgcg cacgcgcaga
      241 cggctgcagg gtccttggtg ctgtggcggt gtggttgatt agggtgctgc tttcaatcgt
      301 gtggcctttg ggaaccccgc gtagccactg ccgcctcctt ctgtcctcgc catgttcctc
      361 actcggtccg agtacgacag gggtgtgaat actttttctc ctgaaggaag attatttcaa
      421 gtggaatatg ccattgaggc tatcaagctt ggttctacag ccattggcat ccagacctca
      481 gagggtgtat gtctagctgt ggagaagaga attacctccc cactaatgga gcctagcagc
      541 attgagaaga ttgtagagat cgatgctcat ataggttgtg ccatgagtgg gctaattgct
      601 gatgctaaaa ctttaattga taaagccaga gtggagacac agaaccactg gttcacctat
      661 aatgagacaa tgacagttga gagtgtgacc caggctgtgt ccaatctggc tctgcagttt
      721 ggagaagaag atgcagatcc aggtgctatg tctcgtccct ttggagtagc attgttgttt
      781 ggaggagttg atgagaaagg accccaactg tttcacatgg acccatctgg gacctttgta
      841 cagtgtgatg ctcgagcaat tggctctgct tctgagggtg cccagagctc cttgcaagaa
      901 gtttaccata agtctatgac tctgaaggag gccatcaagt cctcgctcat catcctcaag
      961 caagtcatgg aggagaagct gaatgcaacc aacatcgagc tagccacggt gcagcctggt
     1021 cagaatttcc acatgttcac aaaggaagaa ctggaggagg tgatcaagga catttaagaa
     1081 ggagccgtcc tcgaacttct gtgggacact ttcagttcta attgccctta gactttattt
     1141 ccagctctta tgtcatggaa aatatccagt atatgtgtgt gtgttttttt atgaagtctg
     1201 tacataacag caattct
//
