LOCUS       NM_001004152            1880 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus pregnancy-specific beta-1-glycoprotein 22 (Psg22),
            mRNA.
ACCESSION   NM_001004152 XM_145414
VERSION     NM_001004152.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1880)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1880)
  AUTHORS   Nakano,T., Aochi,H., Hirasaki,M., Takenaka,Y., Fujita,K.,
            Tamura,M., Soma,H., Kamezawa,H., Koizumi,T., Shibuya,H.,
            Inomata,R., Okuda,A., Murakoshi,T., Shimada,A. and Inoue,I.
  TITLE     Effects of Ppargamma1 deletion on late-stage murine embryogenesis
            and cells that undergo endocycle
  JOURNAL   Dev Biol 478, 222-235 (2021)
   PUBMED   34246625
REFERENCE   3  (bases 1 to 1880)
  AUTHORS   Blois,S.M., Tirado-Gonzalez,I., Wu,J., Barrientos,G., Johnson,B.,
            Warren,J., Freitag,N., Klapp,B.F., Irmak,S., Ergun,S. and
            Dveskler,G.S.
  TITLE     Early expression of pregnancy-specific glycoprotein 22 (PSG22) by
            trophoblast cells modulates angiogenesis in mice
  JOURNAL   Biol Reprod 86 (6), 191 (2012)
   PUBMED   22423048
  REMARK    GeneRIF: expressed early in pregnancy with the ability to induce
            the secretion of proangiogenic factors in immune cell types,
            including uterine dendritic and NK cells
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1880)
  AUTHORS   Wynne,F., Ball,M., McLellan,A.S., Dockery,P., Zimmermann,W. and
            Moore,T.
  TITLE     Mouse pregnancy-specific glycoproteins: tissue-specific expression
            and evidence of association with maternal vasculature
  JOURNAL   Reproduction 131 (4), 721-732 (2006)
   PUBMED   16595723
  REMARK    Erratum:[Reproduction. 2011 Dec;142(6):915]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149065.4.
            
            On Dec 10, 2019 this sequence version replaced NM_001004152.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC080694.1, SRR5189676.79483.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on expression, longest
                                                protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-260               AC149065.4         102085-102344
            261-620             AC149065.4         103450-103809
            621-980             AC149065.4         106739-107098
            981-1340            AC149065.4         108291-108650
            1341-1880           AC149065.4         110713-111252
FEATURES             Location/Qualifiers
     source          1..1880
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.26 cM"
     gene            1..1880
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /note="pregnancy-specific beta-1-glycoprotein 22"
                     /db_xref="GeneID:243862"
                     /db_xref="MGI:MGI:1891354"
     exon            1..260
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1624
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /note="carcinoembryonic antigen-related cell adhesion
                     molecule 1 pseudogene; pregnancy-specific glycoprotein 22"
                     /codon_start=1
                     /product="pregnancy-specific glycoprotein 22 precursor"
                     /protein_id="NP_001004152.1"
                     /db_xref="CCDS:CCDS20876.1"
                     /db_xref="GeneID:243862"
                     /db_xref="MGI:MGI:1891354"
                     /translation="MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPK
                     LVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYR
                     NGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIES
                     VPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGR
                     EIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQL
                     RINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYA
                     HSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVT
                     DSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAG
                     EYQCEAFNPVSSKTSLPVRLTVMNE"
     exon            261..620
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /inference="alignment:Splign:2.1.0"
     exon            621..980
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1340
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1880
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1854..1859
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /note="hexamer: ATTAAA"
     polyA_site      1880
                     /gene="Psg22"
                     /gene_synonym="cea9"
                     /note="major polyA site"
ORIGIN      
        1 gggacagcac tgagagtgga agtgactgag cagtgtcgtg gtcagagacc ccaccaccct
       61 cagcccatag gattctggga tgtgctcctg cctgagagaa aactcagctc agaaggagga
      121 aggacagcag agtccaggtg ccttgcagga gcaaagttct tctcctctga gaaaggccag
      181 tacagtgaga agagatatgg aggtatcctc tgagcttctc agcaatgggt ggacctcctg
      241 gcaaagggtt ctgctcacag cctccctctt aacctgctgg ctcttgccca tcactgccgg
      301 agtcaccatc gaatccgtac cacccaaatt ggttgaagga gaaaatgttc ttctacgagt
      361 ggacaatctg ccagagaatc ttcgagtctt tgtctggtat agaggggtga cagacatgag
      421 cctcggaatt gcattgtatt cacttgacta tagcacaagt gtgacaggac ctaagcacag
      481 tggtagagag acattgtaca gaaacgggtc cctgtggatc caaaatgtca cccgggaaga
      541 cacaggatat tacactcttc aaaccataag taaaaatgga aaagtggtat caaatacatc
      601 catattcctt caggtgaact cctctctttt catctgtggg cgcccttctc cacctgcact
      661 cctcactatt gaatcagtgc cagccagcgt tgctgaaggg ggaagcgttc ttctccttgt
      721 ccacagtctt ccagataatc ttcaatcgct tctctggtac aaagggttga ctgtgtttaa
      781 caaggttgag attgctcggc acagaacagt caagaattca agtgaaatgg gccctgccta
      841 cagcggtaga gagatagtgt acagcaatgg atctctgctg ctccagaatg tcacctggga
      901 agacacagga ttctacaccc tacaaattgt gaacagatat tggaaaatgg aattagcaca
      961 catttacctt caggtggaca cctccctttc ctcgtgctgt gacgatttca actctgtcca
     1021 actgaggatc aatccagtgc caccgcatgc tgctgaaggg gaaagggttc ttctccaggt
     1081 ccataatctg ccagaagatg tgcaaacctt tttgtggtac aaaggcgtct atagcactca
     1141 gagctttaaa attacagagt atagcatagt gacagagtct ctcatcaatg gctatgcaca
     1201 cagtggaaga gagatattgt tcatcaatgg atccctgctg ctccaggatg tcactgagaa
     1261 agactctggc ttctacacac tagtaacaat cgacagcaat gtgaaagttg aaacagccca
     1321 tgtgcaagtc aatgtgaaca agcttgtgac acagcctgtc atgagagtca cggacagcac
     1381 agttcgaata cagggctcag tggtcttcac ttgcttctca gacaacactg gggtctccat
     1441 ccgttggctc ttcaacaatc agaatctgca gctcacagag aggatgaccc tgtccccatc
     1501 aaagtgccaa ctcaggatac atactgtgag gaaggaggat gctggagagt atcaatgtga
     1561 ggccttcaac ccagtcagct caaagaccag tctcccagtc aggctgactg tgatgaatga
     1621 gtgacccctc ctctcatgct ataggagggt ggggcatttc tgtattgaga tgcccacacc
     1681 tacccacctc tgccagtaca tatttccatt cattcgcatg gccagttggc catttctccc
     1741 atccctcccc acacctgatc ctgaacccct ccattttctc ccacatcccc tctcctaccc
     1801 agttccctcc ctctatctgc ttactacaac tatttccccc gcttttatat gagattaaac
     1861 atgcttcctt ggcctcccaa
//
