LOCUS       NM_011964               2547 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus pregnancy specific beta-1-glycoprotein 19 (Psg19),
            mRNA.
ACCESSION   NM_011964
VERSION     NM_011964.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2547)
  AUTHORS   Fan,W., Li,Z., He,X., Wang,X., Sun,M. and Yang,Z.
  TITLE     SLC25A1 regulates placental development to ensure embryonic heart
            morphogenesis
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39591637
REFERENCE   2  (bases 1 to 2547)
  AUTHORS   Lopez-Tello,J. and Sferruzzi-Perri,A.N.
  TITLE     Characterization of placental endocrine function and fetal brain
            development in a mouse model of small for gestational age
  JOURNAL   Front Endocrinol (Lausanne) 14, 1116770 (2023)
   PUBMED   36843585
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2547)
  AUTHORS   Nakano,T., Aochi,H., Hirasaki,M., Takenaka,Y., Fujita,K.,
            Tamura,M., Soma,H., Kamezawa,H., Koizumi,T., Shibuya,H.,
            Inomata,R., Okuda,A., Murakoshi,T., Shimada,A. and Inoue,I.
  TITLE     Effects of Ppargamma1 deletion on late-stage murine embryogenesis
            and cells that undergo endocycle
  JOURNAL   Dev Biol 478, 222-235 (2021)
   PUBMED   34246625
REFERENCE   4  (bases 1 to 2547)
  AUTHORS   Tunster,S.J., Van de Pette,M., Creeth,H.D.J., Lefebvre,L. and
            John,R.M.
  TITLE     Fetal growth restriction in a genetic model of sporadic
            Beckwith-Wiedemann syndrome
  JOURNAL   Dis Model Mech 11 (11) (2018)
   PUBMED   30158284
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2547)
  AUTHORS   Tunster,S.J., McNamara,G.I., Creeth,H.D.J. and John,R.M.
  TITLE     Increased dosage of the imprinted Ascl2 gene restrains two key
            endocrine lineages of the mouse Placenta
  JOURNAL   Dev Biol 418 (1), 55-65 (2016)
   PUBMED   27542691
REFERENCE   6  (bases 1 to 2547)
  AUTHORS   Asanoma,K., Kato,H., Yamaguchi,S., Shin,C.H., Liu,Z.P., Kato,K.,
            Inoue,T., Miyanari,Y., Yoshikawa,K., Sonoda,K., Fukushima,K. and
            Wake,N.
  TITLE     HOP/NECC1, a novel regulator of mouse trophoblast differentiation
  JOURNAL   J Biol Chem 282 (33), 24065-24074 (2007)
   PUBMED   17576768
REFERENCE   7  (bases 1 to 2547)
  AUTHORS   Wynne,F., Ball,M., McLellan,A.S., Dockery,P., Zimmermann,W. and
            Moore,T.
  TITLE     Mouse pregnancy-specific glycoproteins: tissue-specific expression
            and evidence of association with maternal vasculature
  JOURNAL   Reproduction 131 (4), 721-732 (2006)
   PUBMED   16595723
  REMARK    Erratum:[Reproduction. 2011 Dec;142(6):915]
REFERENCE   8  (bases 1 to 2547)
  AUTHORS   Kromer,B., Finkenzeller,D., Wessels,J., Dveksler,G., Thompson,J.
            and Zimmermann,W.
  TITLE     Coordinate expression of splice variants of the murine
            pregnancy-specific glycoprotein (PSG) gene family during placental
            development
  JOURNAL   Eur J Biochem 242 (2), 280-287 (1996)
   PUBMED   8973644
REFERENCE   9  (bases 1 to 2547)
  AUTHORS   Rettenberger,G., Zimmermann,W., Klett,C., Zechner,U. and
            Hameister,H.
  TITLE     Mapping of murine YACs containing the genes Cea2 and Cea4 after
            B1-PCR amplification and FISH-analysis
  JOURNAL   Chromosome Res 3 (8), 473-478 (1995)
   PUBMED   8581299
REFERENCE   10 (bases 1 to 2547)
  AUTHORS   Rudert,F., Saunders,A.M., Rebstock,S., Thompson,J.A. and
            Zimmermann,W.
  TITLE     Characterization of murine carcinoembryonic antigen gene family
            members
  JOURNAL   Mamm Genome 3 (5), 262-273 (1992)
   PUBMED   1638085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK145915.1, BC099467.1, AA408180.1 and AV034276.2.
            
            On Jun 30, 2009 this sequence version replaced NM_011964.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X98111.1, BC099467.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                AK145915.1         3-26
            25-1877             BC099467.1         1-1853
            1878-2020           AA408180.1         229-371
            2021-2547           AV034276.2         102-628
FEATURES             Location/Qualifiers
     source          1..2547
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.31 cM"
     gene            1..2547
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /note="pregnancy specific beta-1-glycoprotein 19"
                     /db_xref="GeneID:26439"
                     /db_xref="MGI:MGI:1347252"
     exon            1..257
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /inference="alignment:Splign:2.1.0"
     CDS             194..1621
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /note="carcinoembryonic antigen 4"
                     /codon_start=1
                     /product="pregnancy specific glycoprotein 19 precursor"
                     /protein_id="NP_036094.2"
                     /db_xref="CCDS:CCDS20877.1"
                     /db_xref="GeneID:26439"
                     /db_xref="MGI:MGI:1347252"
                     /translation="MEVSSELLSNGWTSWQRVLLTASLLTCWFLPITARVTIESVPPK
                     LVEGENVLLRVDNLPENLRVFAWYRGVIKFKLGIALYSLDYNTSVTGPEHSGRETLHS
                     NGSLWIQSATREDTGYYTFQTISKNGKVVSNTSMFLQVYSSLFICGRPSPPALLTIES
                     VPASVAEGGSVLLRVHNLPEHLQSLFWYKGLTMFNKVEIARHRTAKNSIEMGPAHSGR
                     EIVYSNGSLLLQNVTWKDIGFYTLRTLNRYSRIELAHIYLQVDTSLSSCCDAFNSVQL
                     RIDPVPPHAVEGESVLLQVHNLPEDVQTFLWYKGVYSTQDFKIAEYSIVTESIISGRA
                     HSGREIGYTNGSLLLQDVTEKDSGFYTLVTIDSNAKVETAHVQVNVNKLVTQPAMRVT
                     DSTVRVQSSVVFTCFSDNTGVSIRWLFNNQRLQLTERMTLSPSKCQLRIHTVRKEDAG
                     EYQCEAFNPVSSKTSLPVSLAVMNE"
     exon            258..617
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /inference="alignment:Splign:2.1.0"
     exon            618..977
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1337
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..2547
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1853..1858
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /note="hexamer: ATTAAA"
     polyA_site      1879
                     /gene="Psg19"
                     /gene_synonym="Cea-4; Cea4; CGM7"
                     /note="major polyA site"
ORIGIN      
        1 gggcaacact gagagtggaa gtgactgagc agtgctgtgg acacagaccc caccactcac
       61 agcccatagg attctgggaa gtgctcctgc ctgagagaac actcagctca gaaggaggaa
      121 ggacagcaga ggccaggtgc cttgcaggag ctgaaggttt cctcagagaa aggccagtac
      181 agtgagaaga gatatggagg tgtcctctga gcttctcagc aatgggtgga cctcctggca
      241 gagggttctg ctcacagcct ccctcttaac ctgctggttc ctgcccatca ctgcccgagt
      301 caccatcgaa tccgtaccac ccaaattggt cgaaggagaa aatgttcttc tacgagtgga
      361 caatctgcca gagaatcttc gagtctttgc ctggtacaga ggggtaataa aatttaagct
      421 tggaattgca ctgtattcac tggactataa cacaagtgtg acaggacctg agcacagtgg
      481 tagagagaca ttgcacagca acgggtccct gtggatccaa agtgccaccc gggaagacac
      541 aggatattac acgtttcaaa ccataagtaa aaatggaaaa gtggtatcaa atacatccat
      601 gttccttcag gtgtactcct ctcttttcat ctgtgggcgc ccttctccac ctgcactcct
      661 cactattgaa tcagtgccag ccagcgttgc tgaaggggga agcgttcttc tccgtgttca
      721 caatcttcca gagcatcttc aatcgctttt ttggtacaaa gggttgacta tgtttaacaa
      781 ggttgagatt gcccggcaca gaaccgccaa gaattcaatt gaaatgggcc ctgcccacag
      841 cggtagagag atagtgtaca gcaatggatc cctgctgctc cagaatgtca cctggaagga
      901 catcggattc tacaccctac gaactctgaa tagatattcg agaatagaat tagcacacat
      961 ttaccttcag gtggacacct ccctttcctc gtgctgtgac gctttcaact ctgtccaact
     1021 gaggatcgat ccagtgccac cacatgctgt cgaaggggaa agtgttcttc tccaggtcca
     1081 taatctgcca gaagatgtgc aaaccttttt gtggtacaaa ggcgtctata gcactcagga
     1141 ctttaaaatt gcagaataca gcatagtgac agagtctatc atcagtggcc gtgcacacag
     1201 tggaagagag atagggtaca ccaatggatc cctgctcctc caggatgtca ctgagaaaga
     1261 ctctggcttc tacacactag taacaatcga cagcaatgcg aaagttgaaa cagcgcatgt
     1321 gcaagtcaat gtgaacaagc ttgtgacaca gcctgccatg agagtcacag atagcacagt
     1381 tcgagtacag agctcagtgg tcttcacttg cttctcagac aacactgggg tctccatccg
     1441 ttggctcttc aacaatcagc gtctgcagct cacagagagg atgacactgt ccccatcaaa
     1501 atgccaactc aggatacata ctgtgaggaa ggaggatgct ggagagtatc aatgtgaggc
     1561 cttcaaccca gtcagctcaa agaccagtct cccagtcagc ctggctgtga tgaatgagtg
     1621 acccctcctc tcatgctata tcagggtggg ggcatttctg tattgagatg tccacaccta
     1681 cccacccctg ccagttacag atttccattc attcatatgg acagttgtcg atctctccca
     1741 tccctcccca cacctgattc tgatgccctc cattttctcc cacatcccct ctcctaccta
     1801 gttccctccc tccatctgct tcctacgact atttttctcc cttttatgtg agattaaagc
     1861 atgctccctt ggccttccat cttgtttagc atctttggat ctgtgtagtg tagtgtagtg
     1921 tagtgtagtg tagtgtagtg tagtgtagtg tagtgtagtg tgtgtatctt gtattttatg
     1981 gcttatgtcc acttatcagt gagtatatac cctgcatgcc attttgggac tgtgttacct
     2041 cacttaggat gatattctca aattccatcc atttgccttc aaattaatga tgtctttgtc
     2101 tttaatagtt gcaatgtaat ttatggagca cttggtacca cattgtgtct attctttcaa
     2161 gctgcttgtg cccttcacac actgctctgc ttactattgg tagacaatgc agcccaaggg
     2221 gaaaatgttc catttgttct tctttttttt ctttttacat ccaaaacatt tcaataataa
     2281 ggaaaaaatc ataaatctca ataatgcatt tctaatgatc aaaatctcaa gttaaaaaac
     2341 ttcgaccttc aatatccatt gcaagtaaaa gtaacaaaac gtatctgaat acaataaaaa
     2401 ttctgatgat atatagtcat tttatattga ggccacaaat atagtaacat aaacccaagt
     2461 tatctgtgta attaatttta aagtctgaaa tccttggtaa agtttggatc tcttggaagt
     2521 aataaagtta actcttgttt tagtctc
//
