LOCUS       NM_011963               1657 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus pregnancy specific beta-1-glycoprotein 18 (Psg18),
            transcript variant 1, mRNA.
ACCESSION   NM_011963
VERSION     NM_011963.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1657)
  AUTHORS   Fan,W., Li,Z., He,X., Wang,X., Sun,M. and Yang,Z.
  TITLE     SLC25A1 regulates placental development to ensure embryonic heart
            morphogenesis
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39591637
REFERENCE   2  (bases 1 to 1657)
  AUTHORS   Lopez-Tello,J. and Sferruzzi-Perri,A.N.
  TITLE     Characterization of placental endocrine function and fetal brain
            development in a mouse model of small for gestational age
  JOURNAL   Front Endocrinol (Lausanne) 14, 1116770 (2023)
   PUBMED   36843585
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1657)
  AUTHORS   Tunster,S.J., Van de Pette,M., Creeth,H.D.J., Lefebvre,L. and
            John,R.M.
  TITLE     Fetal growth restriction in a genetic model of sporadic
            Beckwith-Wiedemann syndrome
  JOURNAL   Dis Model Mech 11 (11) (2018)
   PUBMED   30158284
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1657)
  AUTHORS   Tunster,S.J., McNamara,G.I., Creeth,H.D.J. and John,R.M.
  TITLE     Increased dosage of the imprinted Ascl2 gene restrains two key
            endocrine lineages of the mouse Placenta
  JOURNAL   Dev Biol 418 (1), 55-65 (2016)
   PUBMED   27542691
REFERENCE   5  (bases 1 to 1657)
  AUTHORS   Sharma,N., Kubaczka,C., Kaiser,S., Nettersheim,D., Mughal,S.S.,
            Riesenberg,S., Holzel,M., Winterhager,E. and Schorle,H.
  TITLE     Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of
            Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest
  JOURNAL   Development 143 (5), 787-798 (2016)
   PUBMED   26811378
REFERENCE   6  (bases 1 to 1657)
  AUTHORS   Kromer,B., Finkenzeller,D., Wessels,J., Dveksler,G., Thompson,J.
            and Zimmermann,W.
  TITLE     Coordinate expression of splice variants of the murine
            pregnancy-specific glycoprotein (PSG) gene family during placental
            development
  JOURNAL   Eur J Biochem 242 (2), 280-287 (1996)
   PUBMED   8973644
REFERENCE   7  (bases 1 to 1657)
  AUTHORS   Ding,Y.P., Remmers,E.F., Du,Y., Longman,R.E., Goldmuntz,E.A.,
            Zha,H., Kotake,S., Cannon,G.W., Griffiths,M.M. and Wilder,R.L.
  TITLE     Genetic maps of polymorphic DNA loci on rat chromosome 1
  JOURNAL   Genomics 36 (2), 320-327 (1996)
   PUBMED   8812459
REFERENCE   8  (bases 1 to 1657)
  AUTHORS   Ishikawa,T.O., Tamai,Y., Rochelle,J.M., Hirata,M., Namba,T.,
            Sugimoto,Y., Ichikawa,A., Narumiya,S., Taketo,M.M. and Seldin,M.F.
  TITLE     Mapping of the genes encoding mouse prostaglandin D, E, and F and
            prostacyclin receptors
  JOURNAL   Genomics 32 (2), 285-288 (1996)
   PUBMED   8833158
REFERENCE   9  (bases 1 to 1657)
  AUTHORS   Bosl,M.R., Seldin,M.F., Nishimura,S. and Taketo,M.
  TITLE     Cloning, structural analysis and mapping of the mouse
            selenocysteine tRNA([Ser]Sec) gene (Trsp)
  JOURNAL   Mol Gen Genet 248 (3), 247-252 (1995)
   PUBMED   7565585
REFERENCE   10 (bases 1 to 1657)
  AUTHORS   Rudert,F., Saunders,A.M., Rebstock,S., Thompson,J.A. and
            Zimmermann,W.
  TITLE     Characterization of murine carcinoembryonic antigen gene family
            members
  JOURNAL   Mamm Genome 3 (5), 262-273 (1992)
   PUBMED   1638085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY713630.1 and BC138857.1.
            
            On Jun 30, 2009 this sequence version replaced NM_011963.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138857.1, AF128236.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                BY713630.1         3-68
            67-1657             BC138857.1         1-1591
FEATURES             Location/Qualifiers
     source          1..1657
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.15 cM"
     gene            1..1657
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /note="pregnancy specific beta-1-glycoprotein 18"
                     /db_xref="GeneID:26438"
                     /db_xref="MGI:MGI:1347251"
     exon            1..254
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..1621
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; carcinoembryonic antigen 3; pregnancy specific
                     glycoprotein 18; carcinoembryonic antigen 3"
                     /codon_start=1
                     /product="pregnancy specific glycoprotein 18 isoform 1
                     precursor"
                     /protein_id="NP_036093.2"
                     /db_xref="CCDS:CCDS20869.1"
                     /db_xref="GeneID:26438"
                     /db_xref="MGI:MGI:1347251"
                     /translation="MELSSELFSNGCTSWQRVLLTASLLTCWLLPTTARVTIESLPPQ
                     VYEGENVLLRVDNMPENLLVFGWYRGMTNLWQAIAQHWLYYYSVMVKGLNHSGREILY
                     INGSLWIQNVTQEDTGYYTFQTISKRGEIVSNTSLYLHVYSSLFICVRPTTLISPTIE
                     LVPASVAAGGSILLLVHNIPKYLQSLFWYKGLIAFNKVEIARYRTAKNSGEPGPAHSG
                     RETVYSNGSLLLQNVTWKDTGFYTLRTLTRYQKMEFAHIYLQVDTSHSLCCDTLDSAQ
                     LSIDPVPRHAAEGGSVLLQVHNLPEDVQTFSWYKGVLSTQDFKIAEYSIATKSIIRGR
                     AHSRREIGYTNGSLLLQDVTEKDSGLYTLITIDSNVRVVTAHVQVNIHQLVTQPAMRV
                     TDSTVRVQSSVVFTCFSDNTGVSIRWLFNNQRLQLTERMTLSPSKCQLRIHTVRKEDA
                     GEYQCEAFNPVSSKTSLPVSLTVMNE"
     exon            255..617
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /inference="alignment:Splign:2.1.0"
     exon            618..977
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1337
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1657
                     /gene="Psg18"
                     /gene_synonym="Cea-3; Cea3; mmCGM6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cactgagagt ggaagtgact gagcacttct atggacacag accccaccgc acacagccca
       61 taggattctg ggaagtgctc ctgcctgaga gaacactcat ctcagaagga ggaaggacag
      121 tagaggccag gtgccttgca ggagctgaag gtgttctcct cagagaaagg ccaatatagt
      181 gagaagagat atggagttgt catctgaact tttcagcaac gggtgtacct cctggcagag
      241 ggttctcctc acagcctccc tcttaacctg ctggctcctg cccaccactg ccagagtcac
      301 cattgaatct ttaccacccc aagtgtatga aggagaaaat gttcttctac gtgttgacaa
      361 tatgccagag aatcttctag tgtttggctg gtacagagga atgacaaatt tgtggcaagc
      421 aattgcacag cattggctgt actactatag tgtaatggtg aaggggctga atcacagcgg
      481 cagagagata ttatacatca acgggtccct gtggatccaa aatgtcacac aagaggacac
      541 aggatattac acttttcaaa ccataagtaa acgaggagaa atagtatcaa atacatccct
      601 gtacttgcac gtgtactcct ctcttttcat ctgtgtgcgt cctactaccc ttatatctcc
      661 gactattgaa ttagtgccag ccagcgttgc tgcaggggga agcattcttc tccttgttca
      721 caatattcca aagtatcttc aatcgctttt ctggtacaaa gggctgattg catttaacaa
      781 ggttgagatt gctcgataca gaacagccaa gaattcaggg gaacctggtc cggcccacag
      841 cggtagagag acagtgtata gcaatggatc actgctgctc cagaatgtca cctggaaaga
      901 cacaggattc tacaccctac gaactctgac tcgatatcag aaaatggaat tcgcacacat
      961 ttaccttcag gtggacacct cccattcctt gtgctgtgac actctcgact ctgcccaact
     1021 cagcattgat ccagtgccac ggcacgctgc tgagggagga agtgttcttc tccaggtcca
     1081 taatctgcca gaagatgtgc aaaccttttc ctggtacaaa ggtgtgctta gtactcagga
     1141 ctttaaaatt gcagaatata gcatagcaac gaagtccatc atcagaggcc gtgcacacag
     1201 cagaagagag atagggtaca ccaacggatc cctgctgctc caggatgtca ctgagaaaga
     1261 ctctggctta tacacactaa taacaataga cagcaatgtg agagttgtaa cagcacatgt
     1321 ccaagtcaac atccatcagc ttgtgacaca gcctgccatg agagtcacag atagcacagt
     1381 tcgagtacag agctcagttg tcttcacttg cttctcagac aacactgggg tctccatccg
     1441 ttggctcttc aacaatcagc gtcttcagct cacagagagg atgaccctgt ccccatcaaa
     1501 atgccaactc aggatacata ctgtgaggaa ggaggatgct ggagagtatc agtgtgaggc
     1561 cttcaaccca gtcagctcaa agaccagtct cccagtcagc ctgactgtga tgaatgagtg
     1621 acccctcctc ttatgctata ggagggtggg ggcattt
//
