LOCUS       NM_007677               2126 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus pregnancy specific beta-1-glycoprotein 17 (Psg17),
            mRNA.
ACCESSION   NM_007677 XM_985818
VERSION     NM_007677.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2126)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2126)
  AUTHORS   Lopez-Tello,J. and Sferruzzi-Perri,A.N.
  TITLE     Characterization of placental endocrine function and fetal brain
            development in a mouse model of small for gestational age
  JOURNAL   Front Endocrinol (Lausanne) 14, 1116770 (2023)
   PUBMED   36843585
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2126)
  AUTHORS   Tunster,S.J., Van de Pette,M., Creeth,H.D.J., Lefebvre,L. and
            John,R.M.
  TITLE     Fetal growth restriction in a genetic model of sporadic
            Beckwith-Wiedemann syndrome
  JOURNAL   Dis Model Mech 11 (11) (2018)
   PUBMED   30158284
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2126)
  AUTHORS   Shimizu,T., Sato,T., Tsukiyama,K., Fujita,H., Kato,S., Hoizumi,M.,
            Shirasawa,H., Narita,T., Terada,Y., Seino,Y. and Yamada,Y.
  TITLE     Food Intake Affects Sperm-Egg Fusion Through the GIP/PSG17 Axis in
            Mice
  JOURNAL   Endocrinology 158 (7), 2134-2144 (2017)
   PUBMED   28430907
  REMARK    GeneRIF: Microarray analysis revealed that pregnancy-specific
            glycoprotein 17 (Psg17), a potential CD9-binding partner, was
            significantly decreased in GIP receptor-knockout (Gipr-/-) testes.
REFERENCE   5  (bases 1 to 2126)
  AUTHORS   Tunster,S.J., McNamara,G.I., Creeth,H.D.J. and John,R.M.
  TITLE     Increased dosage of the imprinted Ascl2 gene restrains two key
            endocrine lineages of the mouse Placenta
  JOURNAL   Dev Biol 418 (1), 55-65 (2016)
   PUBMED   27542691
REFERENCE   6  (bases 1 to 2126)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
REFERENCE   7  (bases 1 to 2126)
  AUTHORS   Zechner,U., Reule,M., Orth,A., Bonhomme,F., Strack,B., Guenet,
            Hameister,H. and Fundele,R.
  TITLE     An X-chromosome linked locus contributes to abnormal placental
            development in mouse interspecific hybrid
  JOURNAL   Nat Genet 12 (4), 398-403 (1996)
   PUBMED   8630493
REFERENCE   8  (bases 1 to 2126)
  AUTHORS   Chen,D.S., Asanaka,M., Yokomori,K., Wang,F., Hwang,S.B., Li,H.P.
            and Lai,M.M.
  TITLE     A pregnancy-specific glycoprotein is expressed in the brain and
            serves as a receptor for mouse hepatitis virus
  JOURNAL   Proc Natl Acad Sci U S A 92 (26), 12095-12099 (1995)
   PUBMED   8618851
REFERENCE   9  (bases 1 to 2126)
  AUTHORS   Rettenberger,G., Zimmermann,W., Klett,C., Zechner,U. and
            Hameister,H.
  TITLE     Mapping of murine YACs containing the genes Cea2 and Cea4 after
            B1-PCR amplification and FISH-analysis
  JOURNAL   Chromosome Res 3 (8), 473-478 (1995)
   PUBMED   8581299
REFERENCE   10 (bases 1 to 2126)
  AUTHORS   Rudert,F., Saunders,A.M., Rebstock,S., Thompson,J.A. and
            Zimmermann,W.
  TITLE     Characterization of murine carcinoembryonic antigen gene family
            members
  JOURNAL   Mamm Genome 3 (5), 262-273 (1992)
   PUBMED   1638085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN703708.1 and BC100345.1.
            
            On Sep 19, 2006 this sequence version replaced NM_007677.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100345.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 CN703708.1         1-3
            4-2126              BC100345.1         1-2123
FEATURES             Location/Qualifiers
     source          1..2126
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.33 cM"
     gene            1..2126
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /note="pregnancy specific beta-1-glycoprotein 17"
                     /db_xref="GeneID:26437"
                     /db_xref="MGI:MGI:1347250"
     exon            1..240
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..1604
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /note="carcinoembryonic antigen 2"
                     /codon_start=1
                     /product="pregnancy specific glycoprotein 17 precursor"
                     /protein_id="NP_031703.1"
                     /db_xref="CCDS:CCDS20878.1"
                     /db_xref="GeneID:26437"
                     /db_xref="MGI:MGI:1347250"
                     /translation="MEVSSELLSNGCTPWQRVLLTASLLSCCLLPTTARVTVEFLPPQ
                     VVEGENVLLRVDNLPENLLGFVWYKGVASMKLGIALYSLQYNVSVTGLKHSGRETLHR
                     NGSLWIQNVTSEDTGYYTLRTVSQRGELVSDTSIFLQVYSSLFICERPTTLVPPTIEL
                     VPASVAEGGSVLFLVHNLPEYLISLTWYKGAVVFNKLEIARYRTAKNSSVLGPAHSGR
                     ETVFSNGSLLLQNVTWKDTGFYTLRTLNRYPRIELAHIYLQVDTSLSSCCHPLDSPQL
                     SIDPLPPHAAEGGRVLLQVHNLPEDVQTFSWYKGVYSTILFQIAKYSIATKSIIMGYA
                     RSRRETVYTNGSLLLQDVTEKDSGVYTLITTDSNMGVETAHVQVNVHKLATQPVIKAT
                     DSTVRVQGSVIFTCFSDNTGVSIRWLFNNQRLQLTERMTLSPSKCQLWIRTVRKEDAG
                     EYQCEAFNPVSSKTSLPVILAVMIE"
     exon            241..600
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /inference="alignment:Splign:2.1.0"
     exon            601..960
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1320
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..2084
                     /gene="Psg17"
                     /gene_synonym="Cea-2; Cea2; mmCGM5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagtgagtg agcagtgctg tggtcacaga ccccaccacc cacagcctat aggattctgt
       61 gaagtgttcc tgcctgagag aaaactcagc tcagaaggag gaaggacagc agaggccagg
      121 tgccttgcag gagctgaagg tctcctcaga gaaaggccag tacagtgaga agagatatgg
      181 aggtgtcctc tgagcttctc agcaatgggt gtaccccctg gcaaagggtt ctgctcacag
      241 cctccctctt atcctgctgc ctcctgccca ccactgccag agtcactgtg gaattcttac
      301 ctccccaagt ggttgaagga gaaaatgttc ttctacgcgt tgataatctg ccagagaatc
      361 ttctaggttt tgtgtggtac aaaggggtgg caagtatgaa gcttggaatt gcactgtatt
      421 cactgcaata taatgtaagt gtgacagggc ttaagcacag cggtagagag acactgcaca
      481 gaaatgggtc cctgtggatc caaaatgtca cctcggagga cacaggatat tacacccttc
      541 gaaccgtaag tcaacgtgga gaactggtat cagatacatc catattcctt caggtgtact
      601 cctctctttt catctgtgag cgtcctacta cccttgtacc tcccactatt gaattagtgc
      661 cggccagcgt tgctgaagga ggaagtgttc ttttccttgt tcacaatcta ccagagtatc
      721 ttatatcact tacctggtac aaaggagcag ttgtgtttaa caagcttgag attgcccgat
      781 acagaacagc caagaattca agtgtgcttg gccctgccca cagcggtaga gaaacggtgt
      841 tcagcaatgg atccctgctg ctccagaatg tcacctggaa agacaccgga ttctacaccc
      901 tacgaactct gaatagatat ccgagaatag aattagcaca catttacctt caggtggaca
      961 cctccctttc ctcgtgctgt caccctcttg actctcccca gctcagtatc gatccattgc
     1021 caccgcatgc tgctgaaggg ggaagggttc ttctccaggt ccataatctg ccagaagatg
     1081 tgcaaacctt ttcctggtac aaaggcgtgt atagcactat attatttcaa attgcaaaat
     1141 atagcatagc aacgaagtcc atcatcatgg gctatgcacg gagtagaaga gagacagtgt
     1201 ataccaatgg atccctgctg ctccaggatg tcactgagaa agactctggt gtgtacacac
     1261 taataacaac agacagcaat atgggagttg aaacagcgca tgtgcaagtc aacgtccaca
     1321 agcttgccac acagcctgtc ataaaagcca cagacagcac agtacgagta cagggctcag
     1381 tgatcttcac ttgcttctca gacaacactg gggtctccat ccgttggctc ttcaacaatc
     1441 agcgtctgca gctcacagag aggatgaccc tgtccccgtc aaagtgccaa ctctggatac
     1501 gtactgtgag gaaggaggat gctggagagt accaatgtga ggccttcaac ccagtcagct
     1561 caaagaccag tctcccagtc atcctggctg tgatgatcga gtgacccatc ctctcatgct
     1621 atagcagggc ggggcatttc tgtattgaga tgtccacacc tacccacccc tgccagttat
     1681 agatttccat tcattcgcat ggccatttgg ccatctctcc catccctccc cacacctgat
     1741 cctgaacccc tccattttct cccacatccc ctctcctacc cagttccatt cctccatctg
     1801 ccttttacta ctatttttcc ccttctacat gagattcaag catcctccct cgggcttcca
     1861 acttgtttaa cttttttgta tctgtgtagt gtagtgtgtg tatcttgtat tttatggcta
     1921 atatccagtt ataagtgagt atataccatg catgccattt tggaacctgg ttacctcact
     1981 caggatgata ctctcaagtt ctatccaaat taatgatgcc ttcaaattaa tgatgtcttt
     2041 gtatttaata gttgcataat acccatggag catatggcac cacaaaaaaa aaaaaaaaaa
     2101 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
