LOCUS       NM_001361930            1621 bp    mRNA    linear   ROD 23-AUG-2023
DEFINITION  Mus musculus serine protease 59 (Prss59), transcript variant 2,
            mRNA.
ACCESSION   NM_001361930 XM_006506690
VERSION     NM_001361930.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Zhang H, Li Y, Cui K, Chen X, Shang C, Min W, Jin P, Jiang Z, Shi
            D, Liu Q and Wang F.
  TITLE     Male fertility in Mus musculus requires the activity of TRYX5 in
            sperm migration into the oviduct
  JOURNAL   J Cell Physiol 235 (9), 6058-6072 (2020)
   PUBMED   32020604
  REMARK    GeneRIF: Male fertility in Mus musculus requires the activity of
            TRYX5 in sperm migration into the oviduct.
REFERENCE   2  (bases 1 to 1621)
  AUTHORS   Choi E, Lee J, Oh J, Park I, Han C, Yi C, Kim DH, Cho BN, Eddy EM
            and Cho C.
  TITLE     Integrative characterization of germ cell-specific genes from mouse
            spermatocyte UniGene library
  JOURNAL   BMC Genomics 8, 256 (2007)
   PUBMED   17662146
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1621)
  AUTHORS   Puente XS and Lopez-Otin C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161768.25 and BC061035.1.
            
            On Mar 30, 2018 this sequence version replaced XM_006506690.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061035.1, AK006951.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                AC161768.25        96827-96847         c
            22-1621             BC061035.1         1-1600
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 18.97 cM"
     gene            1..1621
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /note="serine protease 59"
                     /db_xref="GeneID:73481"
                     /db_xref="MGI:MGI:1920731"
     exon            1..205
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /inference="alignment:Splign:2.1.0"
     exon            206..331
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1047
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /note="protease, serine 59"
                     /codon_start=1
                     /product="trypsin X5 precursor"
                     /protein_id="NP_001348859.1"
                     /db_xref="CCDS:CCDS20041.1"
                     /db_xref="GeneID:73481"
                     /db_xref="MGI:MGI:1920731"
                     /translation="MKTFFIFTLLSLAVANTPKAVLKEYNNSEEYLPENFNVPYMVYL
                     QSSPEPCVGTLIDPQWVLTAAHCSLPTKIRLGVYRPNIKNEKEQICNYSFTVVHPNFD
                     AKLLKNDLMLIKLSYPATINMYVGTIAIAMEPMAFNESCFIPTWTWNNYKNLSDPDIL
                     TWINEYSLSPSDCLDTLHQQKQETRINIMCIGHSLNAMSATKEVSAAPAICSGRVHGI
                     LSWGKASVANGSKGFFTEIHPYARWILKMIRSH"
     exon            332..500
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /inference="alignment:Splign:2.1.0"
     exon            501..751
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /inference="alignment:Splign:2.1.0"
     exon            752..897
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1602
                     /gene="Prss59"
                     /gene_synonym="1700074P13Rik; Tryx5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctccgtttc ctagagactt cactgagact ctgggcactg aacaggaaat ccaggtcctt
       61 aaactcagcg taaccaaaat cgttcaaaat gtctggactg ctgtgttcac ggttcacgtg
      121 gcaaggccat ggcactgata tctaaccatc taaagaatcc cttaatggag tcttctctca
      181 catcagaggg catgctgttc gccagctgtt ctgggcaagg atccaggcgt caagattgcg
      241 acagttgaca gtgtgaccac ctagtttgct ctactgagat tatagcgcga tatgaagact
      301 tttttcatct tcactctctt aagtctcgca gtagctaata ctcccaaagc cgttctgaaa
      361 gaatataaca attcagaaga atacttacca gagaatttta atgttcctta tatggtctat
      421 ctgcagtcca gcccagagcc ttgtgttggg actctcattg accctcagtg ggtgctcacc
      481 gctgctcatt gttctttacc aactaaaatc cgactgggag tttaccgacc caacatcaaa
      541 aatgagaaag aacagatatg taattactca ttcactgtag tccatcctaa ttttgatgca
      601 aaattactga aaaatgactt gatgctgata aaactctcat atcctgctac tatcaacatg
      661 tatgtgggaa ctatagccat agctatggaa ccaatggcat ttaatgaatc ctgcttcata
      721 ccaacatgga cctggaataa ctacaaaaac cttagtgatc ctgacatctt gacatggata
      781 aatgagtatt ctctttcccc aagtgactgt ttggacactc ttcatcaaca gaaacaagaa
      841 acaagaataa acattatgtg cataggacat tcacttaatg ctatgtctgc aactaaggaa
      901 gtatcagctg ctccagccat ctgcagtggg agggtgcatg gaatattgtc ctgggggaaa
      961 gcaagtgtag ccaatggaag caaaggcttc ttcactgaaa ttcatcccta tgcaagatgg
     1021 atcttaaaaa tgatacgatc acactgagaa gtgacaccac tcagtataaa atcatgccgt
     1081 ctgtacaatg gatcaacaat tcatcatctg tcttattgaa aagaacccag ggaaaacacc
     1141 caataaaata tcaccagaaa tctatgactc ctatctttat cataatgtaa actttgagaa
     1201 caatgagaaa tttagtaaca aacttgttta ttcagacaca cacaaaaaat gatcgatcac
     1261 cagacactta gtagattctg attgtgctaa gagaaatgtg tgtgactatg aagtatcctt
     1321 tgtcataatt cagacaattc tgtaatcttg taatgattac tctaatgcag atgatcaata
     1381 gtctacagtg gaacataact ctaactattc tgcacagtgg gagaataacc aaggaagtag
     1441 ataaactaaa tataattgat taaaaaacca aagaagtata tacctgttat gcatcctcaa
     1501 atttatgtgt atataacaac acttgaggga gaaaactggc tttaggggaa ggagaaataa
     1561 tataataaaa taatataata aaataatttt atgtgcccca caaaaaaaaa aaaaaaaaaa
     1621 a
//
