LOCUS       NM_001042710            2693 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus serine protease 57 (Prss57), mRNA.
ACCESSION   NM_001042710
VERSION     NM_001042710.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2693)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2693)
  AUTHORS   AhYoung,A.P., Eckard,S.C., Gogineni,A., Xi,H., Lin,S.J.,
            Gerhardy,S., Cox,C., Phung,Q.T., Hackney,J.A., Katakam,A.K.,
            Reichelt,M., Caplazi,P., Manzanillo,P., Zhang,J., Roose-Girma,M.,
            Tam,L.W., Newman,R.J., Murthy,A., Weimer,R.M., Lill,J.R., Lee,W.P.,
            Grimbaldeston,M., Kirchhofer,D. and van Lookeren Campagne,M.
  TITLE     Neutrophil serine protease 4 is required for mast cell-dependent
            vascular leakage
  JOURNAL   Commun Biol 3 (1), 687 (2020)
   PUBMED   33214666
  REMARK    GeneRIF: Neutrophil serine protease 4 is required for mast
            cell-dependent vascular leakage.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2693)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158376.1 and AC151828.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158376.1, AK153740.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-465               AK158376.1         1-465
            466-2386            AK158376.1         467-2387
            2387-2693           AC151828.3         189848-190154       c
FEATURES             Location/Qualifiers
     source          1..2693
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..2693
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /note="serine protease 57"
                     /db_xref="GeneID:73106"
                     /db_xref="MGI:MGI:1920356"
     exon            1..143
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /inference="alignment:Splign:2.1.0"
     exon            144..297
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /inference="alignment:Splign:2.1.0"
     exon            298..442
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /inference="alignment:Splign:2.1.0"
     exon            443..706
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /inference="alignment:Splign:2.1.0"
     exon            707..2693
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1003..1008
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /note="hexamer: AATGAA"
     polyA_site      1032
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /note="major polyA site"
     polyA_site      1250
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
     regulatory      2647..2652
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /note="hexamer: AATAAA"
     polyA_site      2692
                     /gene="Prss57"
                     /gene_synonym="2900092M14Rik; GLGL782; NSP4; Prssl1;
                     UNQ782"
                     /note="major polyA site"
ORIGIN      
        1 gaaccgttgg gtgcctcctg cacctgcaga cctcaccaga aagatgccat cctctacagc
       61 tatggtgcct gggacaagag gaggctggca ctgtctggtg ctgactacag cagctgccct
      121 gacccagctc atgtggctcc ctggttgctg tgggtcctac attgttggag gccatgaggt
      181 aacgccacat tcccggccct atatggcctc tgtgagcttc gagggccatc actactgtgg
      241 aggcttcctg attcataccc attgggtggt gtcagctgcc cattgcttca gtgacaggga
      301 cccctccatg gggctggtgg tgctgggggc ccacgcactg ctcgccccag agcccacaca
      361 gcagacattt agcattgcag ctgctgtcag ccatcctgat ttccagcctg ccacacaggc
      421 caacgatatc tgcctgctaa ggttgaacgg ctctgctgtc ctgggccccg ctgtgaggct
      481 attacgattg cctcggagaa atgctaagcc acctgctgcg ggcacgcgtt gccatgtatc
      541 cggctggggc ttcgtgtctg actttgagga gcctccgcct ggactgatgg aagtcgaggt
      601 gcgcatactg gatctgagtg tctgcaacag ctcctggcag ggccagctga atcctgccat
      661 gctctgcact cacagtgggg accgccggcg gcgtggtttc tgctcggcag attctggggg
      721 acccttggtc tgtggaagac gggcccatgg tcttgtatct ttctcaggcc tctggtgtgg
      781 tgaccccaag actccggatg tctacactca agtgtcagcg tttgtgacct ggatctggga
      841 tgtggttcgg gcaagttcat cccctggttc tactggacgc tctgtgaggg ctgtttgaat
      901 ttcagccctc tactggggca gacatgaata gcaacctgtg cccactggct cacatctgga
      961 atattccatg gcttgagact tgggctacag gcattcatcc taaatgaaca attgtactga
     1021 gggttgacta cctagataca tggtttatgg tttgatatat ggtcaactcc agccgccgcc
     1081 cttaatccac agtcaccctt gtaaccaaga cccactatgc tgccccctcc tgaactcgtc
     1141 gcttcggggt ggcacctgct ccatccccta tggatcgtga caaactccat taacacagac
     1201 agggactgat atatgtagtg aggacaaaaa tccaaacagt tataactcca ctcttgccat
     1261 cctagcctca gtataacagt tgtcttatcg tctatcattc ctcctggttt gagttgaacc
     1321 cttcactcgg gagccccaga caaggtgcca tttaaggccc tctcgcccct gtacctctgg
     1381 gaccccagag ggtgcacttc ctttccctcc cacccactca gctccaagct tcccagggat
     1441 tcttgaacac gtgccacgtg tctctgaaag ctttcgtgga tcattccacg ctccattcta
     1501 gtcccaggtt caaaggaagg aggcagaaaa tacacggtgg tttctattgt cttttatttc
     1561 cttggtgagg cagaactcca gggtagggga ggctaccata gctcccctgc taaggacact
     1621 tttggggata ttacaagaaa ggcacagctg agaactggag ggtggtgaga aagaccctgg
     1681 gaactccttg cccccaaact ggagggttgg gcaccttccc atagtcttct gttgtggtct
     1741 gacacctttt aagttttttt tttttctttt ttcaaagata agatcttata tagcccaggc
     1801 tggccttgaa ctcataatgt ggccaaggat gaacttaaac tcctgatgcc cttgcctcta
     1861 ctttctaagt actgggatga ggggcctgag ccaacatgtc tgtttatgcg gtgctgggga
     1921 tggagcccgg gctcggtgaa cactagaaaa gcactctcta cctaaatgca ttgcagctcc
     1981 cccttttggc ttccttgaag gcacttgtgg gtgtgggcaa gttgcagcag cagctgtcag
     2041 agtgaaggca gtaattcagt ctggccccaa acagcatctg gctggtgtca ccacctgcag
     2101 ctgggcttgg ggacgagtgg ggctggtggg gaactgcgta aaaactaatg tgggtgtgca
     2161 gggtacaggg cagtgggtgc tagagtgact ctgggtgctc tgggcacagt gaatcctagt
     2221 gtccactggc tgtcctgggc ctgtgagtca gccagggtcc aatgtttcta ccaggtttca
     2281 ccctgagtgg accaaacagg aatgagccca gtgtttctct gacctgatgt tgcccgctct
     2341 ggtctgaggc cagccatatg caaacaccaa ctcatcggct gtgccctgcg acagctccag
     2401 cctagaaagc aggtggggag atcatagcag ggggatctcc atgcagctgc catccctggg
     2461 cagcaggggt cttgggttct aactttgatc ccagtacctg ggtgatggca cataccaact
     2521 attataaaaa tctcccttca gtccttgtga tacgtgctca ggatcccagg gggatcccca
     2581 agtggttcca ggccaggttt gggaaatgtc catgtgacat aaattagaat attttctata
     2641 acaataaata aaatcgggat ggcgtcaaat gccaggccca gtggctgcag ctc
//
