LOCUS       NM_199471               1995 bp    mRNA    linear   ROD 02-FEB-2024
DEFINITION  Mus musculus serine protease 43 (Prss43), mRNA.
ACCESSION   NM_199471 XM_195763
VERSION     NM_199471.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Yoneda,R., Takahashi,T., Matsui,H., Takano,N., Hasebe,Y.,
            Ogiwara,K. and Kimura,A.P.
  TITLE     Three testis-specific paralogous serine proteases play different
            roles in murine spermatogenesis and are involved in germ cell
            survival during meiosis
  JOURNAL   Biol Reprod 88 (5), 118 (2013)
   PUBMED   23536369
  REMARK    GeneRIF: These results strongly suggest that the three paralogous
            Prss/Tessp proteases play different roles in spermatogenesis and
            that Prss42/Tessp-2 and Prss43/Tessp-3 are required for germ cell
            survival during meiosis.
            Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB100999.1.
            
            On Jan 23, 2004 this sequence version replaced XM_195763.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB100999.1, SRR5189685.163067.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1995
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 60.79 cM"
     gene            1..1995
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /note="serine protease 43"
                     /db_xref="GeneID:272643"
                     /db_xref="MGI:MGI:2684822"
     exon            1..436
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..1506
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /note="testis serine protease 3; putative inactive serine
                     protease 43; protease, serine 43"
                     /codon_start=1
                     /product="serine protease 43 precursor"
                     /protein_id="NP_955765.1"
                     /db_xref="CCDS:CCDS23574.1"
                     /db_xref="GeneID:272643"
                     /db_xref="MGI:MGI:2684822"
                     /translation="MGGFCGADRGGFLALLVWLQLLQPLFSGTYKPREDSGVMHRPQR
                     PRRPRSDPEAPAQQSRLKSLSISHPSGVPVSVDRTEIPGSGSPSGTTTKITLENRRSS
                     LGGPFFTDTCGHRITEVDPGSLSAGRKWPWQVSLQSQNEHVCGGSLISHRWVLTAAHC
                     IYEQEEYMVMLGDDMLHSESESVTLVPVQDIIFPSNFDIQTMRNDIALALLYFPVNYS
                     SLIQPVCLPEEPFRVKNGTVCWVTGWGQQNEIDAGFASILLQEVQQRILLQKHCNTLF
                     QRQLGTSKNLVIKGMICGLQDSGQSLCWGDSGNPLVCESDNTWTQVGIMSWGINCNGV
                     PVLSVYTDIAEYNEWVSYVLSQASRMDPMGVLVLYLSLVFPLALLVAL"
     exon            437..685
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /inference="alignment:Splign:2.1.0"
     exon            686..845
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1108
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1269
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1995
                     /gene="Prss43"
                     /gene_synonym="Gm661; Tessp3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgcaggtca gaagagagat gggattcccc cgaactggag ttatgagtgg ctctgagcca
       61 ccagtgtaat aaggaacatg tgggtgctgg gaactgaatc caggtctgaa tctgcaagcg
      121 aggcaagtgc tcccgccccc tttacattta atattgataa gatctagtat accttcaaag
      181 tctctaagac agtgctaccc agttagcttt tgagtggatg actgaggcat ccaacatctt
      241 cgggcttaac tcaggaccac agccgtcctg cccacaggaa ggcacctgca cgagacacta
      301 ctgcggggtg ggggcggggg actaccagaa aaaggattgc ctgaatccaa ggctgggatg
      361 ggtggcttct gtggcgcgga caggggcggc ttcctagccc tcctggtctg gcttcagctt
      421 cttcagcctt tgttcagtgg tacttacaaa cccagggaag attccggagt gatgcaccgg
      481 ccccagaggc cccggagacc ccggagtgac ccagaggccc cggcacagca gagtcgcttg
      541 aaatccctga gtatttcgca cccttcagga gttccggtgt ctgtagacag gactgagatt
      601 ccaggatcag ggtctccttc agggaccaca accaaaatta ccttggaaaa caggaggagc
      661 tctctaggag gaccgttttt tacagacact tgcggccata gaattacaga ggtagatcct
      721 ggaagtttat ctgcagggag gaagtggcct tggcaggtga gtctgcagag tcaaaatgag
      781 catgtttgtg gaggctccct catcagccac cgatgggtgt tgactgcggc ccactgcata
      841 tatgagcagg aggagtacat ggtgatgttg ggtgacgaca tgctgcattc tgaatctgaa
      901 agtgtgaccc tggtcccagt ccaggacatc attttccctt ccaactttga cattcaaacc
      961 atgaggaatg acattgccct tgctctgctg tacttccccg tgaattactc ctcgctcatc
     1021 cagcccgtgt gccttcccga agagcccttc cgagtgaaaa acgggacagt gtgctgggtg
     1081 actggctggg gccaacagaa cgaaattgat gcagggtttg catccattct cctccaggag
     1141 gttcagcaac gcattctcct ccagaagcac tgtaacacgc tgttccagag acagctgggg
     1201 acatcgaaaa acctagtgat taaagggatg atctgcggtc tgcaagactc aggacagagt
     1261 ctttgttggg gagattctgg gaaccccctt gtctgcgaat ctgacaacac gtggacccag
     1321 gtggggatca tgagctgggg catcaactgc aatggagtcc ctgtcctctc agtttacaca
     1381 gacatcgctg agtacaatga gtgggtcagc tatgtcttaa gtcaggcttc ccgtatggat
     1441 cccatgggag tcttggtcct atacctgtct ctggtgtttc ccttggccct cctggtagct
     1501 ctgtgacctc cttaggccct gtcttcctga gagttttgag tctcccactg tgccttttct
     1561 ccattttccc tttctgtctt tctgcccttt cttcaaattc cagttagcag ctattgccac
     1621 agtagactgt ggcagggaga ttgggggctg caaagtgctc tgactggtgt tctggttact
     1681 tgcctcatga tacacccaca cttggtggac taacctggac tagagggcca gcttgcctgc
     1741 taggtggaga accatgactc catgatcttg gggacatctg ccaagaagag ataatatcac
     1801 ctggctctgt ttacatcaca cagcttagtg accactgaaa gagagggaga acaaccgggt
     1861 gtggtggcac acacctgtaa tcccagctct cgggaggcag aggcaggcgg atttctgagt
     1921 ttgaggccag tctaaaaatc taaaaagtga gctccaggac agccagggct acacagagaa
     1981 accctatctc aaaaa
//
