LOCUS       NM_001081399            1384 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus serine protease 33 (Prss33), mRNA.
ACCESSION   NM_001081399 XM_978060
VERSION     NM_001081399.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1384)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1384)
  AUTHORS   Martin-Ibanez,R., Pardo,M., Giralt,A., Miguez,A., Guardia,I.,
            Marion-Poll,L., Herranz,C., Esgleas,M., Garcia-Diaz Barriga,G.,
            Edel,M.J., Vicario-Abejon,C., Alberch,J., Girault,J.A., Chan,S.,
            Kastner,P. and Canals,J.M.
  TITLE     Helios expression coordinates the development of a subset of
            striatopallidal medium spiny neurons
  JOURNAL   Development 144 (8), 1566-1577 (2017)
   PUBMED   28289129
REFERENCE   3  (bases 1 to 1384)
  AUTHORS   Wong,G.W., Yasuda,S., Morokawa,N., Li,L. and Stevens,R.L.
  TITLE     Mouse chromosome 17A3.3 contains 13 genes that encode functional
            tryptic-like serine proteases with distinct tissue and cell
            expression patterns
  JOURNAL   J Biol Chem 279 (4), 2438-2452 (2004)
   PUBMED   14583634
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ893522.1, BC103542.1 and AC122821.4.
            
            On Jun 2, 2009 this sequence version replaced NM_001081399.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY262280.1, BC101950.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                BQ893522.1         23-46
            25-942              BC103542.1         1-918
            943-1384            AC122821.4         29711-30152
FEATURES             Location/Qualifiers
     source          1..1384
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.08 cM"
     gene            1..1384
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /note="serine protease 33"
                     /db_xref="GeneID:353130"
                     /db_xref="MGI:MGI:2661234"
     exon            1..91
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..879
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /note="serine protease EOS; tryptase 6; protease, serine
                     33"
                     /codon_start=1
                     /product="serine protease 33 precursor"
                     /protein_id="NP_001074868.2"
                     /db_xref="CCDS:CCDS37476.2"
                     /db_xref="GeneID:353130"
                     /db_xref="MGI:MGI:2661234"
                     /translation="MRGASHLQILLLLVLGTRMQECAACGQPRMSSRIVGGRDAQDGE
                     WPWQTSIQHRGAHVCGGSLIAPQWVLTAGHCFPRRVWPSEYSVLLGALSLDVRSSHEL
                     LVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSTRIQPVCLPAPGSHPPPGSPCWVT
                     GWGSLSPGVPLPKGRPLQGVRVPLLDSRACDRLYHVGANVPQGERIVLPGNLCAGYRR
                     GHKDACQGDSGGPLTCMESGHWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQARLS
                     L"
     exon            92..115
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /inference="alignment:Splign:2.1.0"
     exon            116..278
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /inference="alignment:Splign:2.1.0"
     exon            279..550
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /inference="alignment:Splign:2.1.0"
     exon            551..720
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /inference="alignment:Splign:2.1.0"
     exon            721..1384
                     /gene="Prss33"
                     /gene_synonym="Eos; mT6; tryptase-6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgagagacc aagctacctg cacccaggcc agttctgaag atacaatgag gggtgcttcc
       61 cacctccaga tcctgctcct gttggtgtta ggaaccagga tgcaggagtg tgcagcttgt
      121 gggcagcccc gcatgtccag ccggatcgtt gggggccggg atgctcagga tggagagtgg
      181 ccgtggcaaa caagcattca gcaccgtgga gcccatgtgt gcggagggtc actcattgca
      241 ccccagtggg tgttgacggc aggtcactgt ttccctagac gggtatggcc gtcagagtac
      301 agtgtgctcc tgggagcact gagtctggac gtcaggtcat cccacgagct cttggttcct
      361 gtgctgcggg tgctgctgcc tcctgactac tctgaggacg aggcccgtgg tgacctggca
      421 ctgctgcagc tgcgtcaccc agtgtccctg agcacccgca tccagcctgt ctgcctgcct
      481 gcaccagggt cccatccacc accagggtct ccatgctggg tcactggctg gggtagcctc
      541 agcccaggag taccactccc aaaggggaga cccttgcaag gagtgagggt gccgctgctg
      601 gactcccgag cctgtgaccg cctctaccac gtgggtgcca acgtgcccca gggtgaacgc
      661 atagtgctac cagggaactt gtgtgctggc taccgcagag gccacaagga tgcctgccag
      721 ggtgactctg gaggacccct gacctgtatg gagtctggcc actgggtcct ggtgggtgtg
      781 gtgagctggg gcaagggctg tgccctgccc aaccgtccag gtgtctatac caatgtggcc
      841 aagtatagtc cctggatcca ggctcgcctg agcctctgat gctggtgggt ctgaaaatgt
      901 gaatctggag cttcctggtc catcccacat tcccctcttt ctcacatgaa gctgagatgc
      961 taagagtcca tctgcctacc cccttccctc ctctcctcct tcaggcccat cttctatcac
     1021 tcagggatct tctgtgagtc ccctgcactt acactctgct ctctcctttt ggctcatctg
     1081 gcctgtatgc cctttgcatc ctggaggaag tcagacagat ttaaagtata agaggaactc
     1141 tacaccaagg agaatctcct ttgctgactt tgaaggttga ggggccagac actgaggaac
     1201 cacaaggcac tgacagccag cagggggaga gaagtctgtg gccaccagga acctccaaca
     1261 ccctggagtc tggatacaat tcccccatct tctaatccct tagcttcatg ctggtaaagc
     1321 cctcaacaga ggacgcaact gagctgcctg agcttttgat ccacagattt ttcgatttaa
     1381 taaa
//
