LOCUS       NM_013921               1469 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus serine protease 30 (Prss30), mRNA.
ACCESSION   NM_013921
VERSION     NM_013921.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1469)
  AUTHORS   Wong,G.W., Yasuda,S., Morokawa,N., Li,L. and Stevens,R.L.
  TITLE     Mouse chromosome 17A3.3 contains 13 genes that encode functional
            tryptic-like serine proteases with distinct tissue and cell
            expression patterns
  JOURNAL   J Biol Chem 279 (4), 2438-2452 (2004)
   PUBMED   14583634
REFERENCE   2  (bases 1 to 1469)
  AUTHORS   Shaw-Smith,C.J., Coffey,A.J., Leversha,M., Freeman,T.C.,
            Bentley,D.R. and Walters,J.R.
  TITLE     Characterisation of a novel murine intestinal serine protease, DISP
  JOURNAL   Biochim Biophys Acta 1490 (1-2), 131-136 (2000)
   PUBMED   10786627
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110262.12.
            
            On Aug 14, 2009 this sequence version replaced NM_013921.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC040348.1, AJ243866.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               AC110262.12        190238-190339       c
            103-129             AC110262.12        189329-189355       c
            130-295             AC110262.12        189050-189215       c
            296-567             AC110262.12        188686-188957       c
            568-728             AC110262.12        188147-188307       c
            729-1469            AC110262.12        187236-187976       c
FEATURES             Location/Qualifiers
     source          1..1469
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.17 cM"
     gene            1..1469
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /note="serine protease 30"
                     /db_xref="GeneID:30943"
                     /db_xref="MGI:MGI:1353645"
     exon            1..102
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..983
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /note="distal intestinal serine protease; transmembrane
                     protease, serine 8 (intestinal); transmembrane serine
                     protease 8; protease, serine 30"
                     /codon_start=1
                     /product="serine protease 30 precursor"
                     /protein_id="NP_038949.2"
                     /db_xref="CCDS:CCDS28470.1"
                     /db_xref="GeneID:30943"
                     /db_xref="MGI:MGI:1353645"
                     /translation="MESRARCIFLLLLQILTRARGDILPSVCGHSRDAGKIVGGQDAL
                     EGQWPWQVSLWITEDGHICGGSLIHEVWVLTAAHCFRRSLNPSFYHVKVGGLTLSLLE
                     PHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTPLRPSQFTPVCLPAAQTPLTPGTV
                     CWVTGWGATQERDMASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAGYV
                     EGQKDSCQGDSGGPLVCSINSSWTQVGITSWGIGCARPYRPGVYTRVPTYVDWIQRIL
                     AENHSDAYGYHSSASAAYQMLLPVLLAVALPGSL"
     exon            103..129
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /inference="alignment:Splign:2.1.0"
     exon            130..295
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /inference="alignment:Splign:2.1.0"
     exon            296..567
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /inference="alignment:Splign:2.1.0"
     exon            568..728
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /inference="alignment:Splign:2.1.0"
     exon            729..1469
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1451..1456
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /note="hexamer: AATAAA"
     polyA_site      1469
                     /gene="Prss30"
                     /gene_synonym="2010015P21Rik; Disp; Disp1; Tmprss8"
                     /note="major polyA site"
ORIGIN      
        1 agatatttca aggactctaa ccccactgcg ttgtggaccg gagaggagcc atggagtccc
       61 gggcaaggtg catctttctt cttttgctgc agatcctgac aagggcacgt ggagatatat
      121 tgccctcagt atgtggccac tcccgagatg ctggaaagat cgtgggtggt caagatgctt
      181 tggaaggaca atggccttgg caagtcagcc tgtggataac cgaggatggc cacatatgcg
      241 ggggctccct catccacgag gtgtgggtgc tcacggctgc ccactgcttc cgcaggtctc
      301 tgaaccctag cttctaccat gtgaaggttg gagggctgac actttccctt ctggaacccc
      361 actcaacttt agtggccgtg aggaacatct tcgtgcatcc cacctacctc tgggcagatg
      421 cgtctagcgg agacattgcc ctggtgcagc tggatactcc tctgcggccc tctcagttca
      481 ctcctgtctg cctcccagca gcccagactc ctctcacccc tgggactgtc tgctgggtga
      541 caggctgggg agccacccag gaaagagaca tggcaagtgt cctccaggag ttagctgtgc
      601 ctctcttgga ctcagaggac tgtgaaaaga tgtaccacac ccaggggagc agcctgtcag
      661 gggagcgaat catccagtcg gacatgctct gtgcaggcta cgtagaaggc cagaaggact
      721 cctgccaggg tgactctgga ggaccgctcg tttgttccat caacagttct tggacccagg
      781 tcgggatcac cagctggggt attggctgcg ctcggccata caggcctggt gtctacactc
      841 gggtgcccac ctatgtggac tggattcaaa ggatcctggc agagaaccac tctgatgcct
      901 atgggtacca ctccagtgcc tctgcagcat accaaatgct gctgccagtg ttgctggccg
      961 ttgccttgcc agggtcccta tgaactgtga gctctagagt tctagatcct cttctgctgg
     1021 gctcggagac tcagaagctc aacatagaca cggagaaaat gaatctccaa tggtggtttt
     1081 gtgtgggacc gtgaaaggta gcttggtccc cagctgagct aaggcttgaa gccctagtac
     1141 ttctgaagga acagtaggtg cttcacctgt actggggtac caggccccgg tcactagctg
     1201 cagaccccca tagatttgta gccatcagtc acataaggac aacgtcccaa gcccctccac
     1261 atgtagagga tatgacccgt ggtcatgtag gctcaagaca gatctccatt ttaatgaggt
     1321 acctaaagga ctggagggct tagccaataa gctttccttc ccagacactc cttccagaaa
     1381 aaaatattta acctcaggcc tgccctgaga aagtggggta cagttttact catccacttt
     1441 ctgccatgac aataaattcc ttaaaacca
//
