LOCUS       NM_001101443            3429 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus proline-rich transmembrane protein 4 (Prrt4), mRNA.
ACCESSION   NM_001101443 XM_149840 XM_913212
VERSION     NM_001101443.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3429)
  AUTHORS   Katayama,S., Tomaru,Y., Kasukawa,T., Waki,K., Nakanishi,M.,
            Nakamura,M., Nishida,H., Yap,C.C., Suzuki,M., Kawai,J., Suzuki,H.,
            Carninci,P., Hayashizaki,Y., Wells,C., Frith,M., Ravasi,T.,
            Pang,K.C., Hallinan,J., Mattick,J., Hume,D.A., Lipovich,L.,
            Batalov,S., Engstrom,P.G., Mizuno,Y., Faghihi,M.A., Sandelin,A.,
            Chalk,A.M., Mottagui-Tabar,S., Liang,Z., Lenhard,B. and
            Wahlestedt,C.
  CONSRTM   RIKEN Genome Exploration Research Group; Genome Science Group
            (Genome Network Project Core Group); FANTOM Consortium
  TITLE     Antisense transcription in the mammalian transcriptome
  JOURNAL   Science 309 (5740), 1564-1566 (2005)
   PUBMED   16141073
REFERENCE   2  (bases 1 to 3429)
  AUTHORS   Carninci,P., Kasukawa,T., Katayama,S., Gough,J., Frith,M.C.,
            Maeda,N., Oyama,R., Ravasi,T., Lenhard,B., Wells,C., Kodzius,R.,
            Shimokawa,K., Bajic,V.B., Brenner,S.E., Batalov,S., Forrest,A.R.,
            Zavolan,M., Davis,M.J., Wilming,L.G., Aidinis,V., Allen,J.E.,
            Ambesi-Impiombato,A., Apweiler,R., Aturaliya,R.N., Bailey,T.L.,
            Bansal,M., Baxter,L., Beisel,K.W., Bersano,T., Bono,H., Chalk,A.M.,
            Chiu,K.P., Choudhary,V., Christoffels,A., Clutterbuck,D.R.,
            Crowe,M.L., Dalla,E., Dalrymple,B.P., de Bono,B., Della Gatta,G.,
            di Bernardo,D., Down,T., Engstrom,P., Fagiolini,M., Faulkner,G.,
            Fletcher,C.F., Fukushima,T., Furuno,M., Futaki,S., Gariboldi,M.,
            Georgii-Hemming,P., Gingeras,T.R., Gojobori,T., Green,R.E.,
            Gustincich,S., Harbers,M., Hayashi,Y., Hensch,T.K., Hirokawa,N.,
            Hill,D., Huminiecki,L., Iacono,M., Ikeo,K., Iwama,A., Ishikawa,T.,
            Jakt,M., Kanapin,A., Katoh,M., Kawasawa,Y., Kelso,J., Kitamura,H.,
            Kitano,H., Kollias,G., Krishnan,S.P., Kruger,A., Kummerfeld,S.K.,
            Kurochkin,I.V., Lareau,L.F., Lazarevic,D., Lipovich,L., Liu,J.,
            Liuni,S., McWilliam,S., Madan Babu,M., Madera,M., Marchionni,L.,
            Matsuda,H., Matsuzawa,S., Miki,H., Mignone,F., Miyake,S.,
            Morris,K., Mottagui-Tabar,S., Mulder,N., Nakano,N., Nakauchi,H.,
            Ng,P., Nilsson,R., Nishiguchi,S., Nishikawa,S., Nori,F., Ohara,O.,
            Okazaki,Y., Orlando,V., Pang,K.C., Pavan,W.J., Pavesi,G.,
            Pesole,G., Petrovsky,N., Piazza,S., Reed,J., Reid,J.F., Ring,B.Z.,
            Ringwald,M., Rost,B., Ruan,Y., Salzberg,S.L., Sandelin,A.,
            Schneider,C., Schonbach,C., Sekiguchi,K., Semple,C.A., Seno,S.,
            Sessa,L., Sheng,Y., Shibata,Y., Shimada,H., Shimada,K., Silva,D.,
            Sinclair,B., Sperling,S., Stupka,E., Sugiura,K., Sultana,R.,
            Takenaka,Y., Taki,K., Tammoja,K., Tan,S.L., Tang,S., Taylor,M.S.,
            Tegner,J., Teichmann,S.A., Ueda,H.R., van Nimwegen,E., Verardo,R.,
            Wei,C.L., Yagi,K., Yamanishi,H., Zabarovsky,E., Zhu,S., Zimmer,A.,
            Hide,W., Bult,C., Grimmond,S.M., Teasdale,R.D., Liu,E.T.,
            Brusic,V., Quackenbush,J., Wahlestedt,C., Mattick,J.S., Hume,D.A.,
            Kai,C., Sasaki,D., Tomaru,Y., Fukuda,S., Kanamori-Katayama,M.,
            Suzuki,M., Aoki,J., Arakawa,T., Iida,J., Imamura,K., Itoh,M.,
            Kato,T., Kawaji,H., Kawagashira,N., Kawashima,T., Kojima,M.,
            Kondo,S., Konno,H., Nakano,K., Ninomiya,N., Nishio,T., Okada,M.,
            Plessy,C., Shibata,K., Shiraki,T., Suzuki,S., Tagami,M., Waki,K.,
            Watahiki,A., Okamura-Oho,Y., Suzuki,H., Kawai,J. and Hayashizaki,Y.
  CONSRTM   FANTOM Consortium; RIKEN Genome Exploration Research Group and
            Genome Science Group (Genome Network Project Core Group)
  TITLE     The transcriptional landscape of the mammalian genome
  JOURNAL   Science 309 (5740), 1559-1563 (2005)
   PUBMED   16141072
  REMARK    Erratum:[Science. 2006 Mar 24;311(5768):1713]
REFERENCE   3  (bases 1 to 3429)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   4  (bases 1 to 3429)
  AUTHORS   Okazaki,Y., Furuno,M., Kasukawa,T., Adachi,J., Bono,H., Kondo,S.,
            Nikaido,I., Osato,N., Saito,R., Suzuki,H., Yamanaka,I.,
            Kiyosawa,H., Yagi,K., Tomaru,Y., Hasegawa,Y., Nogami,A.,
            Schonbach,C., Gojobori,T., Baldarelli,R., Hill,D.P., Bult,C.,
            Hume,D.A., Quackenbush,J., Schriml,L.M., Kanapin,A., Matsuda,H.,
            Batalov,S., Beisel,K.W., Blake,J.A., Bradt,D., Brusic,V.,
            Chothia,C., Corbani,L.E., Cousins,S., Dalla,E., Dragani,T.A.,
            Fletcher,C.F., Forrest,A., Frazer,K.S., Gaasterland,T.,
            Gariboldi,M., Gissi,C., Godzik,A., Gough,J., Grimmond,S.,
            Gustincich,S., Hirokawa,N., Jackson,I.J., Jarvis,E.D., Kanai,A.,
            Kawaji,H., Kawasawa,Y., Kedzierski,R.M., King,B.L., Konagaya,A.,
            Kurochkin,I.V., Lee,Y., Lenhard,B., Lyons,P.A., Maglott,D.R.,
            Maltais,L., Marchionni,L., McKenzie,L., Miki,H., Nagashima,T.,
            Numata,K., Okido,T., Pavan,W.J., Pertea,G., Pesole,G.,
            Petrovsky,N., Pillai,R., Pontius,J.U., Qi,D., Ramachandran,S.,
            Ravasi,T., Reed,J.C., Reed,D.J., Reid,J., Ring,B.Z., Ringwald,M.,
            Sandelin,A., Schneider,C., Semple,C.A., Setou,M., Shimada,K.,
            Sultana,R., Takenaka,Y., Taylor,M.S., Teasdale,R.D., Tomita,M.,
            Verardo,R., Wagner,L., Wahlestedt,C., Wang,Y., Watanabe,Y.,
            Wells,C., Wilming,L.G., Wynshaw-Boris,A., Yanagisawa,M., Yang,I.,
            Yang,L., Yuan,Z., Zavolan,M., Zhu,Y., Zimmer,A., Carninci,P.,
            Hayatsu,N., Hirozane-Kishikawa,T., Konno,H., Nakamura,M.,
            Sakazume,N., Sato,K., Shiraki,T., Waki,K., Kawai,J., Aizawa,K.,
            Arakawa,T., Fukuda,S., Hara,A., Hashizume,W., Imotani,K., Ishii,Y.,
            Itoh,M., Kagawa,I., Miyazaki,A., Sakai,K., Sasaki,D., Shibata,K.,
            Shinagawa,A., Yasunishi,A., Yoshino,M., Waterston,R., Lander,E.S.,
            Rogers,J., Birney,E. and Hayashizaki,Y.
  CONSRTM   FANTOM Consortium; RIKEN Genome Exploration Research Group Phase I
            & II Team
  TITLE     Analysis of the mouse transcriptome based on functional annotation
            of 60,770 full-length cDNAs
  JOURNAL   Nature 420 (6915), 563-573 (2002)
   PUBMED   12466851
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052319.1 and AW455481.1.
            
            On or before Feb 22, 2008 this sequence version replaced
            XM_913212.2, XM_149840.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052319.1, BC140954.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1202              AK052319.1         3-1204
            1203-2281           AK052319.1         1206-2284
            2282-3411           AK052319.1         2286-3415
            3412-3429           AW455481.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..3429
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.35 cM"
     gene            1..3429
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /note="proline-rich transmembrane protein 4"
                     /db_xref="GeneID:101359"
                     /db_xref="MGI:MGI:2141677"
     exon            1..128
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            129..843
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..2900
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /codon_start=1
                     /product="proline-rich transmembrane protein 4 precursor"
                     /protein_id="NP_001094913.1"
                     /db_xref="CCDS:CCDS51734.1"
                     /db_xref="GeneID:101359"
                     /db_xref="MGI:MGI:2141677"
                     /translation="MAGRSCLELGLFCWVLLAVPVGPQPASSVPGAPLTTLTPPPQSE
                     ASMLSLNLGLNFKFHLRGPAAVWGNPVTETHPLSPGLGQESEEEEEGDLRTDPLWELL
                     VGSPGNYLPEWGSAEGSFTPWASSLPPESTSRLSGPTKRPTAHSQPRMGTVTWATALT
                     ATAPPTSAPRPHQSELELKFDVALRAGAAPTLGHRSLPLLPSLRASLAEIAGRLGPFG
                     FFGTTVSPLRNFSRQSYPGTTAHPSFAFEVSDSPGLFGTTGSRPPPLLERKFSSPSLL
                     DSVASPSSASVKTTPVQQDPTVSTSGPDELSPASFGNPSTQPGCEPGSCSEPELLDDL
                     GQPPASPLPLFFLTLEADWAEARARWGLAWEAHVYGAGALFGLVALLALLALALLPWR
                     CPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLPTLVWLLLQDLPLPCLAAGLG
                     LACLLLARPRTPRCPAGLAALLLLGLGLAAAAALGSAVHRPLRPLRLASRGLHAFLAA
                     FLSGLLLALSCWGGRRRRAGAPLGGAGFKGATPVPQVRSPFAPRESWRRAARTAPVAG
                     TFGLLSGALQGYEVLHALGYGSQAGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPA
                     LCSPRVPRRCWAKLFRLSPGHAAPLLPGGWVPGIPDKEPLGSAIARGDAELLQLCALA
                     GPGPDLLLQGGGCRGFEGAGANPTQSTASSPSSDCTVDFRPPSPINLRRSIEEALCSE
                     ALLAPGLFQGPAFGEALPGLGLYRTISLGNKIGAGPSEKSENVPGSPAPPELPSPGAW
                     PPGSSASSGSLCGLSRDSSSMLLCSSPDRPPRCPLVCVLSPPRPSESSPSLPASGSYQ
                     ALSPPSRDSPEHASELQAEEALLQEQFLDACRQIDELSMGSDTIDL"
     exon            844..948
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1074
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..3413
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3393..3398
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3413
                     /gene="Prrt4"
                     /gene_synonym="D330027H18Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggctgagaa cgaggcaccg actctcccgc agctgattgg cagcgctggg tgaatgagtg
       61 cgcgtggggc cggagcagcg aggtggccgt ggctccgcgc tgatgtgcgc gcccgcctgc
      121 cggcccggga cccctgagct gctgaagaag tgagctccct gcccacccgc gttgctgagc
      181 caggtggggc catggcaggc cgcagctgcc tggagctggg gctgttctgc tgggtcctgc
      241 ttgccgtacc tgtgggtcca cagcctgctt cctctgtacc aggtgcccct cttactactc
      301 tgaccccacc acctcagagt gaggcctcta tgctctctct caacctgggg ctaaacttca
      361 aattccatct ccggggacct gctgctgtct ggggaaatcc tgtcaccgag acccatcctc
      421 tctctcctgg actaggccag gagtctgagg aagaggagga aggcgatctg aggactgatc
      481 ccctttggga actgctggtg gggtcccctg ggaactacct cccagagtgg ggctctgctg
      541 aaggcagctt tacaccctgg gcttcctccc tgcctcccga atccacatcc cgcctctcag
      601 ggcccaccaa gcggcccact gctcactctc aacctaggat gggcaccgtg acctgggcca
      661 ctgctctgac agcgacagca cctccaacca gtgctcccag gcctcatcag agtgagcttg
      721 agctgaagtt tgatgtagct ttaagagcag gtgcagcccc cactcttggt catcggtcgt
      781 tacctctgct gcccagcctg cgggccagcc tggcagagat tgctgggcgc ctgggacctt
      841 ttgggttctt tggtaccact gtgtccccac tccggaactt ctcaaggcag agttacccag
      901 gcacaacagc acatccaagt tttgcttttg aagtgtcaga ttctcctggg ctctttggca
      961 ccacggggtc gcgtcctcca cccctcctgg aaaggaagtt ctcaagccca agcctgttgg
     1021 attcagtggc ttccccgagc tctgcctcag tcaagacaac accagtgcaa caagacccca
     1081 ctgtctccac ttctggccca gatgaactct ctcctgccag cttcgggaat ccttcaacac
     1141 agcctggatg tgagccaggc tcttgtagtg agccagagtt gctggatgac ttgggacagc
     1201 cgcctgcctc cccgctgcct ctcttcttct tgaccctgga ggccgactgg gcagaggcta
     1261 gggctcgctg gggtctggcc tgggaggccc atgtatatgg agcaggagct ctcttcggct
     1321 tggtggctct gctggctctg ttagctctgg ccctcttgcc ctggcgctgt ccgccaggcg
     1381 ccccctgcct ggcgttgctg gatctgctgc tgctctccgc ggggaccact cgggccttcc
     1441 cgctcttcta cgacgcctac gggcatcgcg atcggctgcc gactctcgtc tggctactgc
     1501 tgcaggacct tccgctgccc tgcctagctg caggtctggg gctggcttgc ctgctcctgg
     1561 cccgaccgcg cactccgagg tgccccgccg gcttagcggc gctgctgctg ctggggctgg
     1621 ggttggcggc ggcggccgcc ctggggagcg ccgtgcaccg cccgctgcgg ccgctgcggc
     1681 tcgcctcccg cggtctgcac gcctttctcg ctgccttcct gtcggggctc ctgctggcac
     1741 tctcttgttg gggcggccgg cggcggaggg ccggagcacc cttgggaggg gctggcttta
     1801 agggtgctac ccctgtcccg caagtgcgca gtcccttcgc cccgcgggag tcctggaggc
     1861 gagcggcgcg cacagccccg gtggccggga cctttgggct gctgagcgga gccctgcagg
     1921 gctacgaggt gcttcacgcc ctgggctacg gaagccaagc aggcttggag gggccctggc
     1981 cctggtgggc tttccagcta ggtctgcgtc tgggcgaggt gggcgtcgcg ctcccgttag
     2041 cgctgcttgg tctctaccca gcgctctgca gcccacgtgt gccgcggcgc tgctgggcca
     2101 agctcttccg attgtctccg ggacacgctg ctccgctgct gccaggaggc tgggtccccg
     2161 gaatcccgga caaggagccc ctgggtagcg cgatcgcgcg tggggacgca gagctgctgc
     2221 agctatgcgc tctagcaggc ccaggtcccg atctccttct ccaaggtggc ggctgccggg
     2281 gctttgaagg tgccggggcc aacccaacgc agtcaacagc ctcctcccct agcagcgatt
     2341 gcaccgtgga cttccgcccg ccctcaccta tcaacctgcg gcgcagcatc gaggaagccc
     2401 tctgcagcga ggcacttctg gctcctggtc tctttcaggg ccctgccttt ggggaagccc
     2461 tgcctgggct cggtctctac cgcaccatct cattggggaa caagataggg gcaggaccca
     2521 gtgagaagtc cgagaatgtc cctggatccc cagcacctcc tgagcttccc tctcccgggg
     2581 cctggcctcc cggcagcagc gcctcatctg gctctctgtg tggactctca cgggacagct
     2641 cgtccatgct tctgtgttcc agccccgaca ggccccctcg ctgtccctta gtctgtgtcc
     2701 tcagtccccc gcggccctca gaaagcagcc ccagcctccc agcctcagga tcctaccagg
     2761 ccctatcccc accctcccgc gactccccag aacatgcttc tgaactgcag gctgaggagg
     2821 cattgctgca agagcaattc ctggatgctt gtcgacagat tgatgagctg agcatgggca
     2881 gcgacaccat agacctgtga aaaggcagct atctcacagc caagtctttg cccccccccc
     2941 cctctccact ttctggcatc tgatctgctc aagacctcct cactgtaaca attctccaat
     3001 tctgcctggt tcagataact ctgattcttt cccatccagg ggcccctggg tgggtgggtc
     3061 agcaaccagg ctctatgcat tgggaatcag tgccaagttc tctggagcca tggggtgcta
     3121 atgcccctag ctgcaacttt agggtggcag ggttctactt tccttggctg tcaccagcaa
     3181 taaagctcca aggtgctcca ctcctgacca ccatgtccct taccctggtg ctgagtgaaa
     3241 cagctatctt caaaaggctt atagtgccct gtctgggctt catacccacc tctgccatct
     3301 cttcatggaa ctgttcccta acgatggagc tgtggcccaa cagactttat cgcaactgat
     3361 tgggaaatga gcgttttcag agtcaatgta tcaataaaat atttttcaga ggaaaaaaaa
     3421 aaaaaaaaa
//
