LOCUS       NM_001030296            1360 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus proline rich 7 (synaptic) (Prr7), mRNA.
ACCESSION   NM_001030296
VERSION     NM_001030296.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Lee,S.H., Shin,S.M., Zhong,P., Kim,H.T., Kim,D.I., Kim,J.M.,
            Heo,W.D., Kim,D.W., Yeo,C.Y., Kim,C.H. and Liu,Q.S.
  TITLE     Reciprocal control of excitatory synapse numbers by Wnt and Wnt
            inhibitor PRR7 secreted on exosomes
  JOURNAL   Nat Commun 9 (1), 3434 (2018)
   PUBMED   30143647
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  AUTHORS   Hrdinka,M., Sudan,K., Just,S., Drobek,A., Stepanek,O., Schluter,D.,
            Reinhold,D., Jordan,B.A., Gintschel,P., Schraven,B. and Kreutz,M.R.
  TITLE     Normal Development and Function of T Cells in Proline Rich 7 (Prr7)
            Deficient Mice
  JOURNAL   PLoS One 11 (9), e0162863 (2016)
   PUBMED   27657535
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1360)
  AUTHORS   Murata,Y., Doi,T., Taniguchi,H. and Fujiyoshi,Y.
  TITLE     Proteomic analysis revealed a novel synaptic proline-rich membrane
            protein (PRR7) associated with PSD-95 and NMDA receptor
  JOURNAL   Biochem Biophys Res Commun 327 (1), 183-191 (2005)
   PUBMED   15629447
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX241234.1, AK133129.1 and CT009762.8.
            
            On Dec 15, 2009 this sequence version replaced NM_001030296.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133129.1, ERR2680377.399530.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                CX241234.1         1-41
            42-1338             AK133129.1         2-1298
            1339-1357           AK133129.1         1300-1318
            1358-1360           CT009762.8         59635-59637         c
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 30.06 cM"
     gene            1..1360
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /note="proline rich 7 (synaptic)"
                     /db_xref="GeneID:432763"
                     /db_xref="MGI:MGI:3487246"
     exon            1..148
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /inference="alignment:Splign:2.1.0"
     exon            149..797
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /inference="alignment:Splign:2.1.0"
     CDS             386..1195
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /note="synaptic proline-rich membrane protein"
                     /codon_start=1
                     /product="proline-rich protein 7"
                     /protein_id="NP_001025467.1"
                     /db_xref="CCDS:CCDS26546.1"
                     /db_xref="GeneID:432763"
                     /db_xref="MGI:MGI:3487246"
                     /translation="MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEE
                     RLREQNLRALELEPLELEGSLAGSPPGLAPPPPPHRSRLEAPVHAHSHVHVHPLLHHG
                     PAPPHAHPHPHHHALPHPPPPHLAVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPP
                     YSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPA
                     APCPALCLQAERSRRVFPSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV"
     exon            798..1360
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1333..1338
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /note="hexamer: AATAAA"
     polyA_site      1359
                     /gene="Prr7"
                     /gene_synonym="XM_484263"
                     /note="major polyA site"
ORIGIN      
        1 cgccccgcgc ctccagccca acgctccgag cggctttcgt tgccactgtc tgctccccgg
       61 agccgctgcc ggctccaagc ttgggttctg tccgttgggc cgcttgcccc gaggcaggaa
      121 gacgagttcg aagaggatgc ctgggcccgt cgctcgcggc cccgggtgaa gcaggcccgc
      181 gccggccggc gccatgggaa ggagcgggaa ccacagttgc ccctcgccgg catgtgcgcc
      241 tattgagccc cgccgcaggc agcccccggc cgcaggtccc cgagtgacac tggcggcacc
      301 tgggagcgtg gcgcggcccc ggggccacgc cgaggagccc agcgtccagt agagccgccg
      361 aggacctgcc gcttgtgccg cagccatggt gatgtcccag ggcacctaca cgttcctcac
      421 ttgcttcgcc ggcttctggc tcatctgggg tctcatcgtc ctgctctgct gcttctgcag
      481 cttcctgcgc cgccgcctca aacggcgcca ggaggagcga ctaagggagc agaacttgcg
      541 tgccctggag ctggagcccc tcgagcttga gggcagcctg gctggaagtc ctcccggcct
      601 ggcgccgccg ccgccaccgc accgcagccg tctggaggcg cctgtgcacg cgcactcgca
      661 cgtgcacgtg cacccgctgc tgcaccacgg gccggcgccg ccgcacgcgc acccgcaccc
      721 acaccatcac gcactgccgc acccaccgcc gccgcacctc gccgtgccgc cccggccctg
      781 gagctatccg cgccaagcgg aatcggacat gtctaagccg ccgtgctacg aggaggcggt
      841 gctgatggcc gagccgccgc ctccctacag cgaggtgctc acggacactc gcggcctcta
      901 ccgcaagatc gtcacgccct ttctgagccg ccgcgacagc gcggagaagc aggagcagcc
      961 gcctccgagt tacaagcctc tcttcctgga ccggggctat acttcggcgc tgcatcttcc
     1021 cagcgccccg cggcccgccg caccctgccc tgccctctgt ctgcaggcgg aacgcagccg
     1081 ccgggttttc cccagctgga ccgactcaga gctcagcagc cgagagcccc tggagcacgg
     1141 agcttggcgt ctgccggtct ccatcccctt gttcgggagg actacagccg tatagagggg
     1201 cgcccggcgt cccgagcccc acgggcgaac tcctagcctg actgcgaggc tttttaaatg
     1261 cttcccttgg actgcaggga ggggtggggg ggagggaggg atttcttacc ctgtttgtta
     1321 cattttgagg ataataaagg tgtgtgatct gctttggtac
//
