LOCUS       NM_001081224            2224 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus proline rich 16 (Prr16), mRNA.
ACCESSION   NM_001081224 NM_027774 XM_484730
VERSION     NM_001081224.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2224)
  AUTHORS   Yamamoto,K., Gandin,V., Sasaki,M., McCracken,S., Li,W.,
            Silvester,J.L., Elia,A.J., Wang,F., Wakutani,Y., Alexandrova,R.,
            Oo,Y.D., Mullen,P.J., Inoue,S., Itsumi,M., Lapin,V., Haight,J.,
            Wakeham,A., Shahinian,A., Ikura,M., Topisirovic,I., Sonenberg,N.
            and Mak,T.W.
  TITLE     Largen: a molecular regulator of mammalian cell size control
  JOURNAL   Mol Cell 53 (6), 904-915 (2014)
   PUBMED   24656129
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC132481.1.
            
            On or before Jul 25, 2007 this sequence version replaced
            NM_027774.1, NM_001081224.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC132481.1, AK046456.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2224
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 27.97 cM"
     gene            1..2224
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="proline rich 16"
                     /db_xref="GeneID:71373"
                     /db_xref="MGI:MGI:1918623"
     exon            1..192
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..948
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="proline-rich protein 16"
                     /codon_start=1
                     /product="protein Largen"
                     /protein_id="NP_001074693.1"
                     /db_xref="CCDS:CCDS37818.1"
                     /db_xref="GeneID:71373"
                     /db_xref="MGI:MGI:1918623"
                     /translation="MSAKSKGNPSSSSAAEGPPAASKTKVKEQIKIIVEDLELVLGDL
                     KDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKEQANAP
                     LIKPPAHPSAILTVLRKPNPPPPPPRLTPVRCEEPQRVVPTANPVKTNGTLLRNGGLA
                     GRPNKIPNGDICCIPNSNLDKAPLQSLMHRPEKDRSPQAGPRERVRFNEKVQYHGYCP
                     DCESRYNIKNREVHLHSEPVHPPGKIPHQGPLLHPPPHLPNFPLENGGLGISHSNSFP
                     PPTPATVPPPAAPKPQKTILRKSTTTTV"
     exon            193..2224
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1525..1530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1549
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="major polyA site"
     regulatory      1556..1561
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="hexamer: AATAAA"
     regulatory      1560..1565
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="hexamer: AATAAT"
     polyA_site      1577
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="major polyA site"
     polyA_site      1581
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
     regulatory      1599..1604
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1619
                     /gene="Prr16"
                     /gene_synonym="5430406M13Rik"
ORIGIN      
        1 tgtcctgacc tggcttgctc gccccaccga agaatgtcag ccaagtccaa ggggaacccc
       61 tcctcgtcct ccgcagccga gggaccgccg gcagcctcca aaaccaaggt gaaggagcag
      121 atcaagatca tagtggagga tctggaatta gtcctgggcg acctgaagga cgtggccaaa
      181 gaacttaagg aggtggttga ccagattgac accctgacct ctgatctaca gctggaagat
      241 gagatgaccg acagctccaa aacagacact ctgaacagca gctccagtgg gacaacagcc
      301 tccagcatag agaagatcaa agaacaggcc aatgctcccc tcattaaacc tccagcacac
      361 ccgtctgcta tcctgactgt cctgagaaag ccaaaccctc caccgcctcc tccaaggttg
      421 acacccgtga ggtgtgaaga gcctcagaga gtggtgccga ctgccaaccc tgtaaagacc
      481 aatggcaccc ttctgcggaa tggaggctta gcggggaggc ccaacaaaat tccaaatgga
      541 gacatctgct gcatacccaa cagtaacttg gacaaggctc cgttgcagtc tctgatgcac
      601 agacctgaaa aggacaggag tcctcaggca gggcctcggg aacgagttcg gtttaatgaa
      661 aaagtacaat accatggcta ttgtcctgac tgtgagagcc ggtataacat aaagaatagg
      721 gaggtccatt tacacagtga accagtccat ccacctggaa agatcccaca ccaaggacct
      781 ctgctccatc ctccacctca tctccccaat ttcccattag aaaatggggg actgggaata
      841 agccacagta acagtttccc ccctcccaca cctgcaaccg tgcctcctcc cgctgcacca
      901 aaaccacaga agaccatcct gaggaaatcc accactacca cagtgtgata tctgccattt
      961 aagaaaacgt tctgtttgtt tttaattttc tatatgataa acgtaaaata ataagtaatg
     1021 agcactttct actcaagcaa taaaaagccc aaatatatta atctgcattc aacaaagtgg
     1081 cataaaaaat cacgtggtaa gtatgcagag tagcgcctct gtcctggacg tacattgttt
     1141 tctatgttcc atcatcagaa actgcggaaa attgagaaag tatgaatgaa ttttattttt
     1201 ttgtgattga cctaaaacaa actgtgacct tctgattcca agtattttgg tctattataa
     1261 gagctgggat gtcagatatt ttgatttgtt gataaagcca gggcaactca ttccattcat
     1321 gcctatctca tctatgcatt gatgatgtca tagttctccc tttgatctaa tgctttttaa
     1381 taagaatttt aataccgaag gactatttta ttatttttct aaagatgttt gtcaatagtt
     1441 ttgcatcatg aaatgctgag gacactacaa aaaagtttat tttctatact atacaatttg
     1501 aaacatatgt tcaactatat gtataataaa atattttgag ctttggaaat atgtcaataa
     1561 ataatagtaa ataatgagaa agcctaatgt tcctgaggat taaaatgaag tgaaaattac
     1621 ttttaactcc ctgttaacat tcactgaaat ggaaagccag tccccaagag tttgaataag
     1681 gtgatactga ttggatatca cattcgtaga gtaaatatca caacctattc ggtaagtata
     1741 ttcttacaac aatttcttat tatacacctc cattatggta ctcctagaat cagcgatgaa
     1801 agtctttgat gttgtcatgc cttctcacag gactcattgt agataattac actggaaggt
     1861 tggaattttt gccttcagtt taccagagca agctcaaatt ccctgaaaga acacagattt
     1921 ataggacgga agtttcaggt atctctagtc acagggtatg ttcaggaacg gcctttccct
     1981 ttttctcttc taagttgaag ggtgtcagga atttttgatg tcccatatga gaatctcttc
     2041 tctctacctt caaacccaag gctttctcct aagtaatgtt tgccaactta agaaacttag
     2101 ccaacagata gatcagtcag gtcctagatg cactgatttg gactgatgtg atttttttgc
     2161 cttggagata aaaattattt atctctcaag aattagtgtg aggtaaagtg cctgcaggga
     2221 gagg
//
