LOCUS       NM_146026               1406 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus proline rich 15-like (Prr15l), mRNA.
ACCESSION   NM_146026
VERSION     NM_146026.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1406)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 1406)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596384.17.
            
            On Jan 23, 2019 this sequence version replaced NM_146026.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022765.1, SRR5189685.12958.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AL596384.17        148038-148266
            230-272             AL596384.17        150268-150310
            273-1406            AL596384.17        153272-154405
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 60.16 cM"
     gene            1..1406
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /note="proline rich 15-like"
                     /db_xref="GeneID:217138"
                     /db_xref="MGI:MGI:2387599"
     exon            1..229
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            230..272
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            273..1406
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             304..606
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /note="ATPase family, AAA domain containing 4"
                     /codon_start=1
                     /product="proline-rich protein 15-like protein"
                     /protein_id="NP_666138.1"
                     /db_xref="CCDS:CCDS25307.1"
                     /db_xref="GeneID:217138"
                     /db_xref="MGI:MGI:2387599"
                     /translation="MTEVGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGGAEPPGPDAG
                     DPHSDFNSRLEKIVDKNTKGKHVKVSNSGRFKEKKKVRAMLAENPNLFDDRENKGQ"
     regulatory      1387..1392
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1406
                     /gene="Prr15l"
                     /gene_synonym="Atad4; E230006A12Rik"
                     /note="major polyA site"
ORIGIN      
        1 accttgactc ctggagctgc agctcacgca gcaggcaggt acctgcttct gcacctgtct
       61 cttacacctg ccctgcagct gctcctaccc acctctccag gctgagtctg gccagcgcga
      121 caccctggag acaccctctc ctcctccagt ctcacctgcc tgggcagctc ctactgtcaa
      181 ctcctctagg gaaagtcgcg cctccagccc agagcagtcc ggattacagg ccagttcctt
      241 gtgacctgtg gctccttcta cttcaaggag agcagaaagc tctgcctggg tttagggacc
      301 gccatgactg aagttggttg gtggaagctg accttcctcc ggaaaaaaaa atccactccc
      361 aaagtgctct acgaaatccc ggacacctac gcccaaacag agggaggtgc agagccccca
      421 ggacctgacg caggagaccc tcacagcgac tttaacagcc gtctggaaaa gattgtggat
      481 aagaacacta aaggcaagca tgtcaaggtc tccaactcag gccgcttcaa agagaagaaa
      541 aaagttcggg ccatgttggc agagaacccc aacctctttg atgacagaga gaacaaagga
      601 caatgaaagc ggccgaagag aaccatagcg ctgccctgct ccctgccact ggtggggtcc
      661 gaggcaggag cttgccacgc tggcctcttt ggtcacagcc acttggcggt tgatccctgc
      721 tggcaggaac acccggttct taggtttgta tttatgtgcc ccagctttac gaagagcctc
      781 ctcctcctat gatcacatac tctggtccag cgtgaaaact gtgacctaga agtgctgctg
      841 tccttgacac agtggcttgc ctcacaggga ggtggcacag cagagaatag acagagagca
      901 ggacggactc caccctctcc ccaggcaaca gggagaaggg tgaatttgat tcgctgcatc
      961 ctctactttc tctaccgtgt gactgttgcc tgggccaatc cagggagagc aatgtttccg
     1021 gaagtcacgt gaccgtggtt tccttggtgc cagaggcgga gttcttaagc ttgagatcgc
     1081 ctcttaattc aaggagtaaa cttcctggaa ctttgctccc aggagtggag gggcaaggga
     1141 cacgcgtact ccccggggtg ctactgaagg ctagcccaga aatactcctg accttgacca
     1201 ccacttgtgt gggtgctgaa ttacataacc ccaaagagag gcctccctga ccggcccaag
     1261 ggtccaaact ggaggagtgg atgcgggttt ctcccgactc cttccctgat agtatttaag
     1321 acagatgagc accaggagtg aatcctggag ccttggattt tgttggaaaa gtaggtttta
     1381 cttaggaata aacaaggctg cagaaa
//
