LOCUS       NM_001159657            3606 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus proline and serine rich 2 (Proser2), transcript
            variant 1, mRNA.
ACCESSION   NM_001159657
VERSION     NM_001159657.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3606)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3606)
  AUTHORS   Ye,Q., Bhojwani,A. and Hu,J.K.
  TITLE     Understanding the development of oral epithelial organs through
            single cell transcriptomic analysis
  JOURNAL   Development 149 (16) (2022)
   PUBMED   35831953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928735.9.
            
            On Jan 27, 2022 this sequence version replaced NM_001159657.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025867.1, SRR7345562.3234625.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-264               AL928735.9         125837-126100       c
            265-485             AL928735.9         109834-110054       c
            486-738             AL928735.9         98754-99006         c
            739-3606            AL928735.9         94434-97301         c
FEATURES             Location/Qualifiers
     source          1..3606
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 3.62 cM"
     gene            1..3606
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /note="proline and serine rich 2"
                     /db_xref="GeneID:227545"
                     /db_xref="MGI:MGI:2442238"
     exon            1..264
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            265..485
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             348..1763
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /codon_start=1
                     /product="proline and serine-rich protein 2"
                     /protein_id="NP_001153129.1"
                     /db_xref="CCDS:CCDS15671.1"
                     /db_xref="GeneID:227545"
                     /db_xref="MGI:MGI:2442238"
                     /translation="MPGNQQKPESLETDSDTSPSCGLSDLSRGGSLESRCSSSRSRSF
                     TMDDESLKHLTHEEKDVILFFEETLDSLEYDFDEPALCDSGIHCHSPQSLEESPSSHS
                     EPEDVIDLVQPAPASGEAESLPDMPQVTGAPSDTKHGTPFLEGGKQAAENSLPPPDSR
                     GPEVFPLPPSLPVPAPSAPRKELMSPSPPAEHPKLLRSVPTPLVIAQKISEKLAGNEA
                     LSPTSPSKEGRPGEWRTPTSPASRNGDHVGVWHRHTTQSAPKVHRFPSNISVTNSAGK
                     DFNKTISKAAVNVQERKAQVLANINGMSFIAAGDTSSEERWQKAEEQRSGSADGARTL
                     GRAGMAGEPGAPCAGVPARAQQSRAVQTEQPPALANGFQSVHEALRSEPSSFVPTSKT
                     ITFRPDPAVTGKLARQNASRSLYEPRPDGSQDARKRTGSLPRAVGFRPQGITVQFSGR
                     GSTEEARREALRKLGLLKENL"
     exon            486..738
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            739..3606
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3576..3581
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3606
                     /gene="Proser2"
                     /gene_synonym="5430407P10Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggcagcccg ggacgatcgg cgtgcgtgcg tgcacgactt gctggccgga ggacggcgtg
       61 agccccgagg gtctcagtcg gcgtggacac ctgcgacccg cggaggggac ttggctcggt
      121 gagttccgcc ctactgagcg aggccaggcc aagcgcggga caccgggagc ggcagcagct
      181 gtcgggatca tccagggctc ccggtccggg tcttggtaac tggggaagcc ctttgcgcgc
      241 agctggggct ctgtcgtcgc cgagaagacc tccttccctg cctcagaatg gaaccctggc
      301 tcctaccctg ttttctgtga gctagctagt gacagctttg tgtggggatg cctgggaacc
      361 agcagaaacc agagtctctg gagacggact ctgacacgtc gcccagctgc gggctcagcg
      421 acttgagcag aggtggcagt ctggagagcc ggtgcagcag ttcgcggtcc agaagtttca
      481 ctatggatga cgagagcctg aagcacctca cacatgagga aaaggacgtt atcctgttct
      541 ttgaagagac tcttgattcc ctggaatatg actttgacga gccagccctg tgtgacagtg
      601 gcattcactg ccactctcca cagtctctgg aagagagccc ttccagccac tctgagcccg
      661 aagatgtcat cgatttagtg cagcccgcac ctgcgtctgg ggaagctgag agccttccag
      721 atatgcctca agtaacaggg gccccatctg atacaaaaca tggcactcca tttcttgaag
      781 gtgggaaaca agccgctgag aattccctgc caccaccaga ctccaggggc cctgaggtgt
      841 ttcctttgcc gccctccctg cctgtccccg ctccctctgc cccgcgaaag gagctgatgt
      901 ccccctctcc tccagcagag catcccaaac tgctgcgttc tgtgcccact cctctggtga
      961 ttgctcagaa aatatctgag aagttggcgg gcaatgaagc cctgtctccc acatcccctt
     1021 caaaggaagg caggcctggg gaatggagga caccgacttc tccagcttct agaaacggag
     1081 accatgtcgg cgtgtggcat cgacacacga cccagtcagc acccaaggtc catcgcttcc
     1141 ccagcaacat aagcgtgacc aacagcgcag gcaaggactt caacaagacc atctccaagg
     1201 cggctgtcaa tgtgcaggag cgcaaggccc aggtcctggc caacatcaac ggcatgtcct
     1261 tcatcgctgc gggcgacaca tcatcagaag agcggtggca gaaggcggaa gagcagagga
     1321 gtggctctgc ggatggagca cgcaccctgg gcagagcggg catggccggc gagcccgggg
     1381 caccttgtgc aggagtcccg gccagggcgc agcagtcccg ggctgtgcag acagagcagc
     1441 caccggcgct ggcgaacggc ttccagagcg tacacgaggc cctgcgcagc gagcccagct
     1501 ccttcgtccc caccagcaag accatcacct tccggcctga ccccgctgtg accggcaagc
     1561 tggcgcgcca gaatgccagc cgcagcctat acgaaccgcg cccggacggc agccaagatg
     1621 cccgcaagcg cacgggctcg ctcccccggg cggtgggttt ccggccgcag ggcatcacag
     1681 tgcagttctc tggccgcggc tccactgagg aagctcggcg cgaggctctg cgcaaactcg
     1741 ggctactgaa ggagaacttg tgagggccat gggtgagact gctggaatgg cctgggtgga
     1801 acttgtatgt ccacactggg gggtccagtt ctggagctgg gtggcacgaa gtgctgcttg
     1861 tcgggagaga agcttctgcc ccaatcccag tgcagcgcgg agtcaagaga cctgcagggc
     1921 aaggacagcg cccccccacc ccgtgccccc cagctgtcct tttccttttc cggggtcttg
     1981 gaattaggac ctctgggcct ccatgactgc gacttggtcc agactctgat actcaggatt
     2041 ccctctcctc ttcgaaaata aaaaaaaaaa aaaaaaaaga aatgcttgtt aaatttttat
     2101 agtgtcatta tacactttga ggtctagctg ttgtgtgttt gtttttgaag gatggaagtt
     2161 ggcaccttac ggatcggggt tttcttaaca taattttctt tgccccattt tcttaactaa
     2221 aactctaaat gaacccattg gggaagattt actgtaattt ttaatcgtga aagttaaaaa
     2281 tgaggtcgag tttggaaaag ataattttta gaaagcaagt ctcatttgac tctctaaaat
     2341 ctgctcccgg gatgtgtccc tatgagtctg acttgacagg tagctatgct aatgaacatg
     2401 tgagtatcgt gagtcttcgt atactcattc attattaatt acttaagtac ctgcttctga
     2461 agacaccatt atctagaaac tgcacgatat gagcgcttcc ttttctctaa cagatacctt
     2521 ggcattgtga tgagacacta cgaattcttc cttttatgga agtcggctaa ggatacatga
     2581 acttccagta cagtatgctc tgttcccaat taaagcaaca tttcctgatt tcaaataagc
     2641 aagatagttc ctgtttttac ttaacatttt ccagaattta aaggaaagtt tgaatctttg
     2701 tcacctcact agctctgtgt tacaaggtag ctagaaaaca aaaggaaatg atctgctagg
     2761 ctatgctctc agagcagtgt gatttgaagt gatttgaagg agctcacgga actcagttgt
     2821 gcagcatgaa gttttcttcc agattctgtc tgacagagtt gtggccacag tgttattatc
     2881 caagccattt aaggctggag tctccaactt ctaaaaatag ctagggaagg gctggcccaa
     2941 gagccacacc cttctgcctg ctgggccttc cagcacgcac tgtagcagag cccattggtt
     3001 ttcccgtgag tcttactgag actccgactt ctaatgagct gttgaaggac acattcctgg
     3061 tgccccgctt agcctgtagg ttacatacag ggaatgagtg ggttttattt ctttggagca
     3121 aagtctatca actggctcag ctctctctcg ttctcctgaa gccatctcaa acattttaaa
     3181 atttaaggag gggctttaaa ctttttcaag tgctttcaac tttgctgtta attggcatgg
     3241 gtttgctgag gggccaggag gtccctttga caaagtaaga tgccatacac agtgtttgct
     3301 taataactga aggtctcaat acagctgtta ctgaaccttt atagacaatt ccttttctta
     3361 ttataagtag aatgagtgac tgtatattaa tatattctca taattatatc ttgaaaaaca
     3421 aaattttgtc ttacctataa gctactgtat tatgttatgc acgacatttc ctcttaaagg
     3481 gttatctttt ttctattatt tattcatatt tttctctatt taatctatga tgacactgac
     3541 tgttacttta gctgttactt atttccaaag ccctaattaa agtctccttc ttgtgattca
     3601 tgagga
//
