LOCUS       NM_025373               3117 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus protein only RNase P catalytic subunit (Prorp), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_025373 XM_885948 XM_993784
VERSION     NM_025373.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3117)
  AUTHORS   Kuznetsova,I., Siira,S.J., Shearwood,A.J., Ermer,J.A.,
            Filipovska,A. and Rackham,O.
  TITLE     Simultaneous processing and degradation of mitochondrial RNAs
            revealed by circularized RNA sequencing
  JOURNAL   Nucleic Acids Res 45 (9), 5487-5500 (2017)
   PUBMED   28201688
REFERENCE   2  (bases 1 to 3117)
  AUTHORS   Rackham,O., Busch,J.D., Matic,S., Siira,S.J., Kuznetsova,I.,
            Atanassov,I., Ermer,J.A., Shearwood,A.M., Richman,T.R.,
            Stewart,J.B., Mourier,A., Milenkovic,D., Larsson,N.G. and
            Filipovska,A.
  TITLE     Hierarchical RNA Processing Is Required for Mitochondrial Ribosome
            Assembly
  JOURNAL   Cell Rep 16 (7), 1874-1890 (2016)
   PUBMED   27498866
REFERENCE   3  (bases 1 to 3117)
  AUTHORS   Bogenhagen,D.F., Martin,D.W. and Koller,A.
  TITLE     Initial steps in RNA processing and ribosome assembly occur at
            mitochondrial DNA nucleoids
  JOURNAL   Cell Metab 19 (4), 618-629 (2014)
   PUBMED   24703694
REFERENCE   4  (bases 1 to 3117)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK151976.1, AK031144.1 and AV233350.1.
            
            On or before Apr 29, 2009 this sequence version replaced
            XM_993784.1, XM_885948.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK152028.1, AK151976.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1256              AK151976.1         1-1256
            1257-2558           AK031144.1         635-1936
            2559-3114           AK151976.1         2559-3114
            3115-3117           AV233350.1         242-244
FEATURES             Location/Qualifiers
     source          1..3117
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 23.91 cM"
     gene            1..3117
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /note="protein only RNase P catalytic subunit"
                     /db_xref="GeneID:66132"
                     /db_xref="MGI:MGI:1913382"
     exon            1..2248
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
     CDS             1272..3026
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /EC_number="3.1.26.5"
                     /note="mitochondrial ribonuclease P protein 3;
                     mitochondrial RNase P protein 3; mitochondrial
                     ribonuclease P catalytic subunit"
                     /codon_start=1
                     /product="mitochondrial ribonuclease P catalytic subunit
                     precursor"
                     /protein_id="NP_079649.1"
                     /db_xref="CCDS:CCDS49068.1"
                     /db_xref="GeneID:66132"
                     /db_xref="MGI:MGI:1913382"
                     /translation="MTFYLSGFRSIPKLWKSNPYFELGPATSSTPFFLCAIGNQQRWF
                     SVKPTTPPNSKALNLLDTKARTHRKGNDNNGQVSSDPHYFAAGAAKKRSHIGANPQNQ
                     GHALPVRSSVQLPTKPLNSAEWDKLKEDFKGKASFEDFIISQMARNCCSVDVAKSLLA
                     WVAAKNNGIVGYNLLVKYLYLCVFHKQTSEVIDVYEIMKAKYKSLESGGYTLLIRGLI
                     HSDRWRESLLLLEDIKKVMVPSKKNYGDCIQGALLHQDVNTAWNLYQELIGHNLIPPL
                     ETLKAFFDYGKDINDDHYSDKLLDILLYLRNNQLYPGESFAHSIKTWFESIPGRQWKG
                     QFTTIQKSGQCSGCGRTIEPIHLSPEEYEFLKEKIMRDVIDGGDQYKKTTPQELKRFE
                     SFVNSCPPFDIVIDGLNVAKMFPKGRESQNLLGVVSQLAQQNLQLLVLGRKHMLRPSS
                     QWRKEEMEQVRKQAHCFFADNISEDDPFLLYATLNSGNHCKFITKDLLRDHKACLPDA
                     RTQRLFFKWQQGHQLAIMKGFQKSKLTFQHILSYDTVVQRTGDSWHIPYDEDLVQRSS
                     CEVPTKWLCLQRKTPDPC"
     exon            2249..2296
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2297..2429
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2430..2537
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2686
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2687..2882
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
     exon            2883..3117
                     /gene="Prorp"
                     /gene_synonym="1110008L16Rik; mKIAA0391; Mrpp3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctttccag tccatggttg actcccgctc agaggaccct acatttgcag tttgttaaga
       61 gctccaccca ctgccagccg cgacgtcaga cttcgccaag acaggtggaa gttaattagg
      121 acgcctggac gccatcttgg gcacgggcgg aagccttggc tacaaaggaa aaaaagaaaa
      181 aaggaaagga aagatgctgt agctattccg gatacggcga tcacgctagc atggacgaaa
      241 atcagacatg aagtagatga aaaaattatc cttcttacgg aggtgtcgca gctcaccaag
      301 ccggatttct aaaggccaga agaagcctgc gtgacttctt cgcttgggca tttagcgcgt
      361 gcgcgccaca ggttacggga ctccattgcc atttccgaat tgagaaaagc attttcgtca
      421 cattttgttc tttctctgga aaccttaacc gttcctacga tgtaatagac gcagcggtat
      481 ccagccctct cggatactaa aagtttcaaa attatcctgg tttgtttatc ttctcagtac
      541 tcaacagaac cctggaattc aagcgctcca ggccccagca ccacgttcag cgcggtgcgt
      601 tgtgggtatt gtagttttca ccgcgtttat ggttccttta agcatgagtg gcgtggtgag
      661 ttgtttaatg aagtgaactt cgtttgtcga ccctccgtac agttaagtct gagctctttc
      721 tggacctcac ttccttccct atgatgttta tgctgcattt ccatggcccc tcttctccga
      781 agagttttgc ggcccggaga gagttgtgaa gagcaaggga ccctagactg gcttttcttg
      841 ctactgctgg ggctgcgatt ggtggttcct gttcgttgtt atttatttcc ctgttctagc
      901 tcctttggta tcccgcccct cttcgggacc atcataatcc acacgagtca aactgggagt
      961 ccatgtgctt tttcctcaga ttcgaaaatt ggaaggtaac aggcacttca ggattcccgt
     1021 tccgccttct ggtttaggga ttgctactgg tgttggacgt ctttggatcc ttatttaata
     1081 aatagaacac gtgtgctttc cttaccatta catcgctcca aacacatagt cttgatttgt
     1141 ttgtaacgga gaaacaaaaa aagtctcact ttcaagaact gcgcttccat atcctcgggc
     1201 ccccaatacc ttaattttac gtagtggagt gaaactgttt tatttttaag tttcattcaa
     1261 ctcactgcag catgaccttc tatttgtctg gttttcggag catcccgaaa ctttggaaga
     1321 gcaaccctta ctttgagcta ggccctgcga cctcttctac ccccttcttt ctctgtgcca
     1381 tcgggaacca acaaagatgg ttttctgtta aacctactac ccctccaaat agcaaagcac
     1441 tcaatctact ggataccaaa gctaggacac acaggaaagg gaatgacaac aatgggcagg
     1501 tttcttctga tcctcattac ttcgctgctg gagcagctaa gaagaggtcc cacataggtg
     1561 ctaaccctca gaatcaaggt catgccttgc ccgtgagaag ctctgtccaa cttccaacta
     1621 aacctttgaa ttccgcagag tgggataaac ttaaagaaga tttcaaagga aaggccagtt
     1681 ttgaagactt catcatttca cagatggcac gcaactgttg ttcagtagat gtggccaagt
     1741 ctctcctggc ttgggtagca gcaaagaaca atggcatcgt gggctataat ctactcgtca
     1801 agtatttata tctctgtgtc tttcataagc agacgtcaga agttattgat gtctatgaaa
     1861 tcatgaaagc caagtacaag agtttagaat ctgggggtta tacccttctc atccggggat
     1921 tgatccactc agacagatgg agagagtcct tgttgctgtt agaagacatt aaaaaagtca
     1981 tggtcccttc caaaaagaac tatggtgact gtatacaagg agccctcctt catcaagatg
     2041 tgaacacagc ttggaatttg tatcaggaat tgataggtca taatctcatc cctccgttgg
     2101 aaactctaaa agccttcttt gattatggca aagacataaa tgatgatcac tattcagaca
     2161 aactcctgga catacttttg tatctaagga ataatcagct gtatcctgga gagtcatttg
     2221 cacacagtat aaaaacgtgg tttgaaagta tccctggaag acaatggaaa ggacagttca
     2281 ccacaattca gaaaagtggc cagtgctcag gctgtggcag aactatagag cctattcatc
     2341 tgagtccaga agagtatgag tttctgaagg aaaaaatcat gagggatgtg atagatggcg
     2401 gcgaccagta taagaagacg acacctcagg aactgaagag attcgagagc tttgtgaact
     2461 cctgtcctcc ttttgatatc gttattgatg gcctcaatgt tgcaaaaatg tttcctaagg
     2521 gtcgtgaatc tcaaaatctc ctgggtgtgg tttctcagct agcccagcag aatctacagt
     2581 tgctggtcct aggccggaag cacatgctga gacccagttc ccagtggaga aaggaagaga
     2641 tggagcaggt gcgaaagcaa gcccactgtt tctttgctga taacatctca gaggatgatc
     2701 ctttccttct gtacgccaca ctgaactcag gcaatcactg caagtttatc accaaagacc
     2761 tgttgcggga ccacaaggcc tgcctgccgg atgcccggac tcagcgcctg ttctttaagt
     2821 ggcagcaggg acatcagctg gcaatcatga aagggtttca aaaatcaaaa ctaactttcc
     2881 agcatatcct cagctatgac acagtggtac aaaggactgg agactcctgg cacattcctt
     2941 atgatgaaga cctggtgcag agatcctcct gtgaagtgcc aaccaaatgg ctgtgcctcc
     3001 agagaaagac acccgacccc tgctgagtcg catggcctcc tggctggttc acagctctta
     3061 tatccatgct gatgtctgcc atgacctctg tcctggaaat aaaaagattt tagtaac
//
