LOCUS       NM_001081240            2781 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus protein arginine methyltransferase 9 (Prmt9),
            transcript variant 1, mRNA.
ACCESSION   NM_001081240 XM_486137
VERSION     NM_001081240.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2781)
  AUTHORS   Bai X, Sui C, Liu F, Chen T, Zhang L, Zheng Y, Liu B and Gao C.
  TITLE     The protein arginine methyltransferase PRMT9 attenuates MAVS
            activation through arginine methylation
  JOURNAL   Nat Commun 13 (1), 5016 (2022)
   PUBMED   36028484
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2781)
  AUTHORS   Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E and
            Torres-Padilla ME.
  TITLE     Single-cell profiling of epigenetic modifiers identifies PRDM14 as
            an inducer of cell fate in the mammalian embryo
  JOURNAL   Cell Rep 5 (3), 687-701 (2013)
   PUBMED   24183668
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY336855.1, CJ075954.1, AK045315.1 and AC113049.22.
            
            [WARNING] On Dec 20, 2023 this sequence was replaced by
            NM_001081240.4.
            
            On Mar 20, 2007 this sequence version replaced NM_001081240.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045315.1, AK154546.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                BY336855.1         2-67
            67-333              CJ075954.1         60-326
            334-2180            AK045315.1         324-2170
            2181-2181           AC113049.22        73481-73481
            2182-2403           AK045315.1         2172-2393
            2404-2781           AK045315.1         2395-2772
FEATURES             Location/Qualifiers
     source          1..2781
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 36.61 cM"
     gene            1..2781
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /note="protein arginine methyltransferase 9"
                     /db_xref="GeneID:102182"
                     /db_xref="MGI:MGI:2142651"
     exon            1..340
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..2692
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /EC_number="2.1.1.320"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative protein arginine N-methyltransferase 10; putative
                     protein arginine N-methyltransferase 9; protein arginine
                     methyltransferase 10 (putative)"
                     /codon_start=1
                     /product="protein arginine N-methyltransferase 9 isoform
                     1"
                     /protein_id="NP_001074709.1"
                     /db_xref="CCDS:CCDS40394.1"
                     /db_xref="GeneID:102182"
                     /db_xref="MGI:MGI:2142651"
                     /translation="MPNSRPRPRRGAGGGAGAAGRDRLVARSLQSAEHCLGDQDFGTA
                     YAHYLLVLSLAPELKDDVKETFQYTLFKWAEELHALSRIQDLLGCYEQALELFPDDEV
                     ICNSMGEHLFRMGFRDEAAGYFHKAVKLNPDFNDAKENFYRVANWLVERWHFIMLNDT
                     RRNMVYNAAIQKAVCLGSRTVLDIGTGTGILSMFAKKAGAQSVYACELSKTMYELACD
                     VVAANKMENGIKLLHMKSLDIEIPKHIPERVSLVVTETVDAGVFGEGIVESLIHAWEH
                     LLLQPKTKEENGNCGKYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGIHLPTNVK
                     FQSPAYTSVDTEETVEPYTTEKMSGIPGGYLPLTECFQIMKVDFNNLQELKSLATKKP
                     HSLNVPAIKEGVLDAIMVWFVLQLDDEYSLSTSPSEETCWEQAVYPVQALEDYCIQPG
                     DRVTMEASCHDCYLRIQGISILHLEHEMEVMKGFTKSKDLLSLGNEAELCSALANLQT
                     SRPEALEQTCMLEPTEIALLNNIPYHEGFKTAMRKVLSSLAPELLWQPMDTHCQYMEM
                     NSGSGQSDAAPSTADPFYVLDVSEGFSLLPILAGTLGHVKPYSSVEKDQHCIALDLIA
                     EANHFPKETLEFWLRHIEDEAAVLQRPKSDKLWSIIILDVIEPSGLIQQELMEKAAIS
                     RCLLQSGGKIFPQYVLMFGMLVESQTLVEESAVQGTEHTLGLNIAPFINQFQVPIRVC
                     LDLSSLPCVPLSQPVELLRLDLMTPYLNTSNKEVKVRVCRSGRVTAVPFWFHLCLDDE
                     VRLDTSGEASHWKQAAVVLDNPIQVQAGEELVLSVEHHKSNVSIAVKP"
     exon            341..489
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            490..726
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            727..894
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            895..997
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1104
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1297
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1481
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..2199
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            2200..2353
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..2476
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     exon            2477..2781
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2759..2764
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /note="putative"
     polyA_site      2781
                     /gene="Prmt9"
                     /gene_synonym="Prmt10"
                     /note="putative"
ORIGIN      
        1 gtccgccgct gggaaggcgg ggcttcctgc tgtgtgcacc cagtgcctct gtgcgtccag
       61 ttgctgcgac cggcccaggg aagcgcgccg tggagactct tttcccggac gaggccatcc
      121 tccttcgtgg gcttccgagc gagacttatc catgccgaac tcgaggccca ggccccgccg
      181 gggcgccggg ggtggcgcag gtgcggccgg ccgggaccgg ctggtggcac ggtccttgca
      241 gagtgctgag cactgtctag gtgaccagga cttcggcact gcttatgccc attaccttct
      301 ggtgctcagc ctggcgccag agctaaaaga cgacgtgaag gaaacttttc agtatacact
      361 tttcaagtgg gctgaagagc ttcatgcact gagccgaata caagacttac ttggttgcta
      421 tgagcaggcc ttggagctgt ttcctgatga tgaagtgatt tgcaacagta tgggagagca
      481 cctcttcaga atgggctttc gagatgaggc agctggctat tttcacaaag cagtgaagct
      541 aaaccctgat ttcaatgatg caaaggagaa cttttaccgc gtagcaaact ggctggtgga
      601 gcgctggcac ttcatcatgc ttaatgacac caggagaaac atggtttata atgcagcaat
      661 ccagaaggca gtgtgcctgg gctccagaac cgttctggat atcggcacgg ggactggaat
      721 actgagcatg tttgctaaaa aagctggcgc acaatcagta tatgcctgtg aattatccaa
      781 gaccatgtat gaactcgcct gtgatgtagt ggctgcaaac aagatggaaa atgggataaa
      841 gcttctacat atgaagtcac ttgatataga aattccgaag cacattcctg aaagagtgtc
      901 cctagttgta acagaaactg tcgatgcagg tgtatttgga gaaggaattg tggagagttt
      961 aattcatgca tgggaacatt tacttctgca accaaagacc aaagaagaaa atggaaattg
     1021 cgggaagtat gggaaagtga taccagccgg tgctgttata tttgggatgg cagtcgagtg
     1081 tgcagagata cgaaggcatc atagggttgg tgctaaggac attgctggta tacatttacc
     1141 aacaaatgtg aaatttcaga gcccagccta tacttctgtt gatacagaag aaacagttga
     1201 accctacaca actgaaaaga tgagtggcat ccccggagga tacctgcctt tgacggagtg
     1261 ctttcagatt atgaaagttg atttcaataa tcttcaggaa ttaaaaagtc ttgcaactaa
     1321 gaagccacac tctcttaatg ttcctgctat taaagaaggc gtgctagatg ctattatggt
     1381 ttggtttgtt ctccagcttg atgatgaata cagcttgtcc acaagtccta gtgaggaaac
     1441 ctgttgggaa caggctgttt atccagtaca ggcccttgaa gactactgca tacagcctgg
     1501 tgaccgagtg acaatggagg catcttgtca cgattgttac ctaagaatcc aggggatcag
     1561 tatcttgcat ttggaacatg aaatggaagt tatgaaaggt tttaccaaga gtaaagactt
     1621 gctttctcta ggaaatgaag ctgaactctg tagtgctctg gctaaccttc agaccagtag
     1681 accagaagcc ctggagcaga cttgtatgtt agagcccaca gagattgctt tgcttaataa
     1741 cattccgtat catgaaggct ttaagacagc gatgaggaag gtgttgtctt cactggcccc
     1801 agagctgctg tggcagccca tggatactca ctgtcagtac atggagatga actctgggag
     1861 tggacagagt gatgctgcac caagcaccgc tgaccctttc tatgtgctcg atgtgtctga
     1921 aggcttctct cttttgccta tacttgccgg aacacttggt catgttaaac cctacagttc
     1981 agtggagaaa gaccagcatt gtatcgcttt ggacctcata gctgaagcca accacttccc
     2041 taaggaaaca cttgagtttt ggctgcgaca tatagaggat gaagctgctg tgttgcaaag
     2101 gcccaaatca gacaaattgt ggagcataat tatactagat gtcattgagc catctgggct
     2161 tatccagcag gagctgatgg aaaaggctgc aatatccaga tgtttattgc agtctggagg
     2221 caagatcttc ccacagtatg tgctgatgtt tgggatgctt gtggagtccc agacgctggt
     2281 agaagagagt gcggttcaag ggacagaaca tactcttggg ctaaacatag caccttttat
     2341 taaccagttt caggtgccta tccgggtatg tctggattta tcttctttgc catgtgtccc
     2401 tttaagccaa ccagtggagc tgttgaggtt ggatctgatg actccatatt tgaacacttc
     2461 caataaagaa gtaaaggtcc gtgtgtgcag gtctggtcga gtgaccgctg ttccattttg
     2521 gtttcatctg tgcctggatg acgaggtgag gctggacacc tcaggtgaag cctcccactg
     2581 gaaacaagct gcagttgttc tggataatcc catccaagta caagcgggag aggagcttgt
     2641 gctcagcgtt gagcatcaca aaagcaacgt cagcatcgca gtgaagccgt gagattgtca
     2701 tcgaacaatg aatgtgtgaa aatccctgga gtcatcaaaa atgtttaagg gttgcaataa
     2761 taaagcccat gttaaaagtc t
//
