LOCUS       XM_006520037            9746 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus prolactin receptor (Prlr), transcript
            variant X4, mRNA.
ACCESSION   XM_006520037
VERSION     XM_006520037.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000081.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006520037.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9746
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="15"
     gene            1..9746
                     /gene="Prlr"
                     /gene_synonym="Pr-1; Pr-3; Prlr-rs1"
                     /note="prolactin receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 10
                     mRNAs, 17 ESTs, 239 long SRA reads, 16 Proteins, and 98%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:19116"
                     /db_xref="MGI:MGI:97763"
     CDS             175..2001
                     /gene="Prlr"
                     /gene_synonym="Pr-1; Pr-3; Prlr-rs1"
                     /codon_start=1
                     /product="prolactin receptor isoform X1"
                     /protein_id="XP_006520100.1"
                     /db_xref="GeneID:19116"
                     /db_xref="MGI:MGI:97763"
                     /translation="MSSALAYMLLVLSISLLNGQSPPGKPEIHKCRSPDKETFTCWWN
                     PGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATN
                     EMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWLPPTITDVKTGWFT
                     MEYEIRLKSEEADEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWGQEKS
                     IEIPNDFTLKDTTVWIIVAVLSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDT
                     HLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDNEDERLMPSHSKEYPGQGVK
                     PTHLDPDSDSGHGSYDSHSLLSEKCEEPQAYPPAFHIPEITEKPENPEANIPPTPNPQ
                     NNTPNCHTDTSKSTTWPLPPGQHTRRSPYHSIADVCKLAGSPGDTLDSFLDKAEENVL
                     KLSEDAGEEEVAVQEGAKSFPSDKQNTSWPPLQEKGPIVYAKPPDYVEIHKVNKDGVL
                     SLLPKQRENHQTENPGVPETSKEYAKVSGVTDNNILVLVPDSRAQNTALLEESAKKVP
                     PSLEQNQSEKDLASFTATSSNCRLQLGRLDYLDPTCFMHSFH"
ORIGIN      
        1 ttcatcttct atttcctgaa acaagcaccc aagtgttaac tggcttgtga aataccttgg
       61 ctaaagaacg cttctctgtg gaggtgagca tcgcagatgt tttgcacatg aaccctgaag
      121 ggagcctctg atctattgcc tgtagcaaga agaagggcca gcctgaagca aaacatgtca
      181 tctgcacttg cttacatgct gcttgtcctc agcatcagcc tcctgaatgg acagtcacca
      241 cctggaaaac ctgaaatcca caaatgtcgt tcccctgaca aggaaacatt cacctgctgg
      301 tggaatcctg ggtcagatgg aggactcccc accaattatt cattgacata cagcaaagaa
      361 ggagagaaaa acacctatga atgtccagac tacaaaacca gtggccccaa ttcctgtttc
      421 tttagcaagc agtacacttc catatggaaa atatacatca tcacagtaaa tgccacgaac
      481 gaaatgggaa gcagtacctc ggatccactt tatgtggatg tgacttacat tgttgaacca
      541 gagcctcctc ggaacctgac tttagaagtg aaacaactaa aagacaaaaa aacatatctg
      601 tgggtaaaat ggttgccacc taccataact gatgtaaaaa ctggttggtt tacaatggaa
      661 tatgaaattc gattaaagtc tgaagaagca gatgagtggg agatccactt cacaggtcat
      721 caaacacaat ttaaggtttt tgacttatat ccaggacaaa agtatcttgt ccagactcgc
      781 tgcaagccag accatggata ctggagtaga tggggccagg agaaatctat tgaaatacca
      841 aatgacttca ccttgaaaga cacaactgtg tggatcattg tggccgttct ctctgctgtc
      901 atctgtttga ttatggtctg ggcagtggct ttgaagggtt atagcatgat gacctgcatc
      961 tttccaccag ttccggggcc aaaaataaaa ggatttgata ctcatctgct agagaagggc
     1021 aagtctgaag aactgctgag tgccttgggg tgccaagact ttccccccac ttctgactgt
     1081 gaggacttgc tggtggagtt cttggaagtg gatgacaatg aggacgagcg gctaatgcca
     1141 tcccattcca aagagtatcc gggtcaaggt gttaaaccca cacacctaga tcctgacagt
     1201 gactctggtc atggaagcta tgacagccat tctcttttgt ctgaaaagtg tgaggagccc
     1261 caggcctacc cccctgcctt ccacatccct gagatcactg agaagccaga gaatcctgag
     1321 gcaaatattc ctcccacccc aaatccccaa aataacaccc ccaattgtca tacagataca
     1381 tccaaatcta caacatggcc tttaccacct ggccaacaca cgcgcagatc tccttaccac
     1441 agcattgccg atgtgtgcaa gctagctgga agtcctggag atacactgga ctctttcttg
     1501 gacaaagcag aggaaaatgt tctaaagttg tctgaagatg ctggagagga agaagtggct
     1561 gtgcaagaag gggccaaaag cttcccttct gacaaacaaa acacatcttg gccaccactc
     1621 caggagaaag gccccattgt ctatgctaaa cccccagatt acgtggagat tcacaaagtc
     1681 aacaaagacg gagtgctatc attactcccc aagcagagag aaaaccacca gacagaaaac
     1741 cctggggttc ctgaaaccag taaggagtat gccaaggtat ctggggtcac ggataacaac
     1801 atcctggtgt tagtgccaga ctcacgagcc cagaacacag ctttgcttga ggaatcagcc
     1861 aagaaggttc caccatcgct tgaacagaac caatctgaga aagatctggc cagctttact
     1921 gcaacctcaa gcaactgcag actccaactg ggcaggctgg attacctgga tcctacgtgc
     1981 ttcatgcact cctttcactg agagctagac ttatggacag attgactaaa atgtgatttc
     2041 tcttcaggtt aacactacag agtcatgaag taatgtggtc tgctaacaga tgttacagga
     2101 tgtgggtata aaaaaaaaaa acaaaaagaa aaaaaaaaca aaaagaaaaa cactacttca
     2161 ctcctccaca cgcttgtgtt cagcatttgc ctctttccaa cagctgattt ccagaacaaa
     2221 tcaacttgtt tcctgtgatt tgtacatttg ctctttgcta ccatatatat gtgtgtgcat
     2281 atatatgcat atatacatgc gcatatatat atattcaatg aaataaaagc acatcgctta
     2341 ctattcttga gggatggtgc caacaggtac agcctctgca atagatttgt catcagacag
     2401 aaggcatgaa atagtcaaaa tggcctagca caagaagatg acggacaggc tggaaatgcc
     2461 atgaaaatgg ctcttaagaa ctgatggcta agcctttaca ctcctctttc attttcatga
     2521 tgatggtccc aatattgcac attttggaaa gaatacattc caggacacca gccaaattgt
     2581 ttacatccgt ccctgtacct taatgaccca ttgcctgtat gcaaatggta tcatgccccc
     2641 agtgttttct taaggtgatt tgaatatgtt aagcctgggt tattctgctg aaactttatt
     2701 ttattctaag gcttcttaag tgtgtagttt gaggaagtaa aattttcata caaaataagg
     2761 ccaatgaatt ccacgcagtg aaccttttca aacgtgttcc ttgcttcatt tgagcaagag
     2821 atggtttgtt ataaacccta gtgttttctt agtagaaaaa agcgattccc ccaagactaa
     2881 cgatctaaaa ggtaatcatt gcaggatgct aatagaagtg ttgccttact gtacatacga
     2941 ttctacttta atacaaaccc gtaagtttag caatgtattt ttgaagacta tttttctatc
     3001 gcttaagtaa agactatttt ctaacttccc agtactgctg tttacgtagt caagtgagta
     3061 gagtgatttc tgctgcaacg ttacagtgag tattcaaagt ttatcagtat atgcagtccc
     3121 tgttagactg aagtgccagg caacccattg cccactgagg aatgcaaagt agatgaaaac
     3181 ctcaattgag tacaatagag taaggtttat ctgattattt ttatccctag gatacgttaa
     3241 acagcaacca tcactgactt tgggttttag ggctttctat agacccataa cacatttctc
     3301 ccatgagttt agggcatctg cccacctatg gaagagtctc ccaaaccacc atgaacaagg
     3361 gcagtgattt ctatggaggg tttccaagac agagatctga ctttgttttg tttcctttta
     3421 tctgagcaat cctgaacaca aaaggatttt aagtataacg aacgtcagca tctccttgga
     3481 attcatgcat ttgcaagatc ttggcacagg ctgtgctcac gtcacagatg tccagataaa
     3541 agttttagga aagcaagcat ctgcccagtg ataacagttt taaaggtcag gggatggtag
     3601 aatctgcaag ccaactccaa gggcaggctt cctgggaaag ttcaaagcaa agccttgggt
     3661 ctccattgga ccatagcatc tatgactcac tctccctctg ctttgcaaat cagttctctc
     3721 tttcaccaac tggatataga gactctgaaa tcacctcttg tgagttcagc attccaccca
     3781 acatgcacat gccctcagag attctccgac gaaggaaaag aaacaaagga aacgcttcca
     3841 gaactacaaa tgcaagcagc caaagcttat attcctaata tataagacat cttgtgaaca
     3901 acagaagtat ttgggaaagt tgtccaagct catgcaatac cctgaatcct ccatacagaa
     3961 tgtctgagaa acaactgcat cttcaaagac acagagaatt ggagtctgaa tcgtactgca
     4021 ttcactaagc tcccaggcat gcgcaagctg aagaagaagc agttttctct atgaccattt
     4081 tcataaaaag ttatttttct ctccctctct tggaaagtat ggagaaaagt ttattatctt
     4141 gaaatgagca acaatgtatg taaatagaaa acaagatcaa aactcttagt gatttaaagt
     4201 tcacgtagca atgttgctta tataaagtca cacaagacca tgacatgcaa aatacacaca
     4261 acctccaaga gggtcagtga atctaattca cctggaaagc taccaacaaa aaaataaata
     4321 aataaacacc aaagccaatg caagctaaac cttctttgcc aagacattct atccttctcc
     4381 aggagacaaa taaatgcatt tatttacaaa tcaccactat aaaattgatg ctgcatatat
     4441 ggctcatagt atgaaatttc taaaaattgg ctttagatat gtaattttga aaatgtggaa
     4501 aatatggcta tctaaagtca agttacattc cacaaaaata agttagcatt catgagataa
     4561 aaacaaatct atacagttct atacatttat taaattcttg tggtcaaata ttttctattg
     4621 aaagacagct gcttgaataa aagaaggcac actaggagtt gagacacctg ggttctagtt
     4681 ctgttttgcc ttggaaagaa gaattaccta ttctagtttt ctttgtattg gacccaataa
     4741 tctctacagc cttttggaat tcagtcttct tgattctgtg gcttgatgaa taatcaaaac
     4801 caatcccttg catctcagtg aggttttcag gcaattataa aaatgcagag ccacccacat
     4861 tcctgtgctc atcctgtttc actctttaaa gtctcagcac ccatttgtct ctacatactg
     4921 aacatgtatt tcatattata tggacaccat gtaagtcaga ctctaggatc atatggtgat
     4981 atgggtgctg aggtaagata tagcgctaag aaagacacag gagatgagac acaagtcttt
     5041 agccatgctc attcctacat ggagccaaca gcctcaaact tctgttcttg tatttggttg
     5101 ttgcctgttt tctcatcatc ctgtttaatg aataaccatt gcccatatag attaaagaat
     5161 cttttgcgct gaatcatttc aaaatgtata gttttctaag caactctctg aaaaatttca
     5221 agttatgaag tacatggaaa ctaaatatat tcatttggat ggctgatgga actttaggac
     5281 acaaatggca gaatgttctc tgataagttt taacaagtac atagaaggaa cttcatatga
     5341 gcacaactta ccatcagcaa tgccactgac ttttaataga tgatacattc tcctaagtgc
     5401 ctgagactaa tcatggtggt cagttatagg tcaatgattc actgtaaacc agtttggtgg
     5461 aaaacagtca agcccatgtt gcatgtgtaa aattaaagcc gggggactct ttacttgatc
     5521 caaggtgaat cctcagtcaa tgaacaacca aaggacctga actccaggtt aaagtttgtc
     5581 ctgatggaaa actagctcct ccattttcat tctgctttag ctgctcatca tttgtaaaat
     5641 gacccagcct gcccttagca acttcaattt agcatagaca agggagaaag agatctgtat
     5701 atgttttaca aagtgccttt ctttgcttct aaaaggtttc attttggaag aaaagtgcat
     5761 taattggaaa gcaaatttta tcttaaatgg atttctttta aataaatgga gagatgacca
     5821 aaaaaaggag gggagatgac aaaatgttct aaagactaac gaacaaaatg tgcagggatt
     5881 tttgtgtata gtttaactga atcatcagag aactgaagtg aatagtatca atcattttgc
     5941 ctgagtctgg gcgtgattgg agatgaaccc aggagcctgt aattcaagac tttccattct
     6001 gaaaacaatg ttgattcatt cttgaatgac actgaattgt atgcctggcc ccgaagaggc
     6061 caatgtgtgc actttgaagc tcttcaccca gatggaaaag tagtaatgac cttgaatatc
     6121 tatcctgtga cttgttatgg atgaaagctt tatatataca tcatcaaaca aggtttcttt
     6181 tgtgactttt tttggctcaa gcacaatact gattctggta ggagagtctc tgagccctca
     6241 gtgtccagct ctgggcatgt tactgctact aaataggctg caagaccttg attttttttt
     6301 ttaattctga ccacttgttt cccctcttgt aggttaaccc tccaaaaaaa aaaaaaaaaa
     6361 aaaagcttct acaatttctt ctaggtctgt ctttaatcct catgagttaa gtaaaatcta
     6421 agattgtagt tgaaaggccc aggggccatg gccaacacgc ccctaactta gacagtaaat
     6481 gcctgaaact gtgtaaagac atgcttaaca gaaacctgag atccagatct ccaaatcagt
     6541 tagaccagaa ctcttgtatt ctgcctcctt accatttcta cattcttaga gccttttcag
     6601 cccctctttc cagggcctgc tattctccct aaagattaat tatgcagaat agtaaagttg
     6661 gggtctgcgg gaaagaaatt acctacaaac aatgatttga ctctgcataa gatgaaccaa
     6721 ttgttaactc tccacacaga cacaaaccta aattatggtc ataaataatg cttcgttttg
     6781 atatgtatgt gtttaaagat tcaagccagc aacttatttt ctaataagtc tgggatgtct
     6841 tgatgagtag atgttgactg ccttaaaaag aaactttaaa aaagtatact gttttcttca
     6901 gagtttatga ttcaacaaaa gaatctactt ataattacag tcctttccta tgagtattag
     6961 gtgttatctg tgaatcacat gcagattttc ctcttggagt tttttttccc aaaaagataa
     7021 ctttaggttt gagctctgcc ggtatcaatt tccagtggag gggaaaggta aaaaacagaa
     7081 tgttccaaaa tgtagggcat atcagaactc caccaaatgg ggtattcatt cactcaaatc
     7141 ttaccagaaa tggtaaatct acatgtaatt gtgagtgaat tgcagagagg taaacataac
     7201 ttctaagacc ataggctaac agcagttctg ttcacgccaa ttccttctat ctcgagttat
     7261 aaagcattga gacacataga gtagaaaggc aaccatctat acagtctggt caatgagtaa
     7321 agggactcac agataatctt agcatgttga ttagtattta cctactgttg tttaaaaaga
     7381 gaagaagaaa ttctaaaaaa aaaaatttgt aacagaaaca ggactatcaa acataaacct
     7441 tatcagttat ggtcaaatta tgcccccctg gatacacttc aaaatacagg cttggttttt
     7501 ctgtgcacat tttgcaaatg gggggttgtc ttttatcaca tcctctaaaa tacaaacaat
     7561 aaaaaagaaa ttttaagaga aaaacacctc tgaaaatcat ttgttttact aaattctgag
     7621 aaacagattt tgaattttta aaactacctc ccttccacat cctaatggcc ttccttcaaa
     7681 gctgcttata gttagaaatg aaagatacca catttttatg tttggactgg tgttgatgga
     7741 atatttgata tacttttcat gtgacactcc taactctaaa gtatgttatt ttactgtaaa
     7801 gaatgttatt ttacactatt ttgctttttt gtgattcaaa acccttatat gccatattga
     7861 agtatataat cctcttattg taaaatttat catgtaatac aagtgataat cattatttaa
     7921 tgacttatga tctaatcata tctaatttca atataattat gtcaatgtct gtaaagcaaa
     7981 gctaaatcta tataatcatg tatgtaatca tatttctgtt gaaactgtga atgttgtgac
     8041 tttcccttta atctttgtct acaagtgata gtgtatgtca ttgtataact gacttgggat
     8101 gctagtgtgt ttacagtaca attcaccagt ggttgaaatg tcaacccttt ggcttggctt
     8161 cttgtgatcc ccgagtgttc tctgcacctt gagacttgct tttgtgcttt gtgctctgtc
     8221 attaatttta aacaatgtaa gagtctcttg tataaaccaa agtaatcagc ccactgagtg
     8281 atcatgcctt ctgtaaagcc atattgaagt aaagactccg ctgtagcata aggtcccctg
     8341 tctccagagc tgccactacc tcgctcctgc tctttcccta caaaatgcca aacaaagttt
     8401 aacccttaag tggaatatta gatgtgcttg ctattattgt catttttaac ctgataataa
     8461 accttctaat tcattacttt gcagatgtat gctaggtttt atgaataacc attttcacat
     8521 tttgatattt tgtagacatt gcctgatgag caaagttcaa aaagagtaca cactcagtca
     8581 tcagatttaa aaaaataatc acagagtgca ggtgtttttc ctgtcagtga gtcacctcaa
     8641 gttgggtggc caaagcaact ataaccttgg tcactatagc tgaaataccc aactcagtgc
     8701 ctggctcaaa gatgtttatc cccttggtct cccttggttc tcattttttt ttaattaggt
     8761 atttatttca tttacatttc caatgctatc ccaaagtccc acacatggtc ctccacctac
     8821 tccctcaacc acccactctc acttcttggc cctggagttc ccctgtactg aggcatataa
     8881 agtttgcaca atcaatgggc ctctctttcc actgatggca gactaggcca tcttctgata
     8941 catatgcagc tagagacaaa agctccgggg gtatttagtt catattgttg ttccacctat
     9001 agggttgcag atctccccag ctccttgggt attttctcta gctcctccat tgggggccct
     9061 gtgatccgtc caatagttga cttctgtgtt tgctaggccc cagcatagtc tcacaagaga
     9121 cagctatatc ttggtccttt tttgttgctg ttgtttgaaa tgcaaatgaa cagaatcact
     9181 tggatgtgga tgaagtgagt tttctaattt ttggctgtca gatctgtaat cataaatttg
     9241 caatttcatt tccccaaact cccaaaaaat aaatatcctc tttacttgat tttaatcatc
     9301 aaatatctag tggtattgaa agagtcagcc atttatcaga aacaatcttg ttttgaactt
     9361 aaagactcat ttctatgtct cactactgtg atatcgactt tttctttagt attaaagggt
     9421 gatatgatgc taaactctta tgatttatcc tcctacattt tttactctgc aaatcttggg
     9481 ttattgcaca ttgtacttcc tagtttttat gaatttattc acttgtctcc atccactttg
     9541 tagggacaac atggacagtt aaatctttgt cagttatatg aacataatgc taatttctct
     9601 catattttta ttgcatgcta aaaataatgc ttgccaaatg gaatcttaga catcccagaa
     9661 taatatggtc actatatttc tatttctgtc attattgaaa atacccagct cagtgcctgg
     9721 ctcaataaat gtttgttttc ctggct
//
