LOCUS       NM_001311125            1003 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus prolactin family 8, subfamily a, member 81 (Prl8a8),
            transcript variant 1, mRNA.
ACCESSION   NM_001311125 XM_006516796
VERSION     NM_001311125.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Roberts,G.A.G. and Tunster,S.J.
  TITLE     Characterising the dynamics of placental glycogen stores in the
            mouse
  JOURNAL   Placenta 99, 131-140 (2020)
   PUBMED   32798765
REFERENCE   2  (bases 1 to 1003)
  AUTHORS   Vrooman,L.A., Rhon-Calderon,E.A., Chao,O.Y., Nguyen,D.K.,
            Narapareddy,L., Dahiya,A.K., Putt,M.E., Schultz,R.M. and
            Bartolomei,M.S.
  TITLE     Assisted reproductive technologies induce temporally specific
            placental defects and the preeclampsia risk marker sFLT1 in mouse
  JOURNAL   Development 147 (11) (2020)
   PUBMED   32471820
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1003)
  AUTHORS   Inagaki,M., Nishimura,T., Nakanishi,T., Shimada,H., Noguchi,S.,
            Akanuma,S.I., Tachikawa,M., Hosoya,K.I., Tamai,I., Nakashima,E. and
            Tomi,M.
  TITLE     Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to
            Placenta-to-Maternal Hormone Signaling and Labor Induction
  JOURNAL   iScience 23 (5), 101098 (2020)
   PUBMED   32408168
REFERENCE   4  (bases 1 to 1003)
  AUTHORS   Eaton,M., Davies,A.H., Devine,J., Zhao,X., Simmons,D.G.,
            Mariusdottir,E., Natale,D.R.C., Matyas,J.R., Bering,E.A.,
            Workentine,M.L., Hallgrimsson,B. and Cross,J.C.
  TITLE     Complex patterns of cell growth in the placenta in normal pregnancy
            and as adaptations to maternal diet restriction
  JOURNAL   PLoS One 15 (1), e0226735 (2020)
   PUBMED   31917811
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1003)
  AUTHORS   Koppes,E., Shaffer,B., Sadovsky,E., Himes,K., Barak,Y., Sadovsky,Y.
            and Chaillet,J.R.
  TITLE     Klf14 is an imprinted transcription factor that regulates placental
            growth
  JOURNAL   Placenta 88, 61-67 (2019)
   PUBMED   31675530
REFERENCE   6  (bases 1 to 1003)
  AUTHORS   Hayakawa,K., Nakanishi,M.O., Ohgane,J., Tanaka,S., Hirosawa,M.,
            Soares,M.J., Yagi,S. and Shiota,K.
  TITLE     Bridging sequence diversity and tissue-specific expression by DNA
            methylation in genes of the mouse prolactin superfamily
  JOURNAL   Mamm Genome 23 (5-6), 336-345 (2012)
   PUBMED   22193412
REFERENCE   7  (bases 1 to 1003)
  AUTHORS   Tunster,S.J., Tycko,B. and John,R.M.
  TITLE     The imprinted Phlda2 gene regulates extraembryonic energy stores
  JOURNAL   Mol Cell Biol 30 (1), 295-306 (2010)
   PUBMED   19884348
REFERENCE   8  (bases 1 to 1003)
  AUTHORS   Simmons,D.G., Rawn,S., Davies,A., Hughes,M. and Cross,J.C.
  TITLE     Spatial and temporal expression of the 23 murine
            Prolactin/Placental Lactogen-related genes is not associated with
            their position in the locus
  JOURNAL   BMC Genomics 9, 352 (2008)
   PUBMED   18662396
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 1003)
  AUTHORS   Soares,M.J., Alam,S.M., Duckworth,M.L., Horseman,N.D., Konno,T.,
            Linzer,D.I., Maltais,L.J., Nilsen-Hamilton,M., Shiota,K.,
            Smith,J.R. and Wallis,M.
  TITLE     A standardized nomenclature for the mouse and rat prolactin
            superfamilies
  JOURNAL   Mamm Genome 18 (3), 154-156 (2007)
   PUBMED   17476555
REFERENCE   10 (bases 1 to 1003)
  AUTHORS   Wiemers,D.O., Shao,L.J., Ain,R., Dai,G. and Soares,M.J.
  TITLE     The mouse prolactin gene family locus
  JOURNAL   Endocrinology 144 (1), 313-325 (2003)
   PUBMED   12488360
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY035367.1 and AK005568.1.
            
            On Jul 24, 2015 this sequence version replaced XM_006516796.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005568.1, AK167369.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 BY035367.1         2-3
            3-1003              AK005568.1         2-1002
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 12.49 cM"
     gene            1..1003
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /note="prolactin family 8, subfamily a, member 81"
                     /db_xref="GeneID:74188"
                     /db_xref="MGI:MGI:1921438"
     exon            1..94
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..789
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; prolactin-8A8; PLP-C gamma2; PRL-like protein
                     C3; prolactin-like protein C-gamma; placental
                     prolactin-like protein C3; growth hormone d14"
                     /codon_start=1
                     /product="prolactin-8A8 isoform 1 precursor"
                     /protein_id="NP_001298054.1"
                     /db_xref="CCDS:CCDS79173.1"
                     /db_xref="GeneID:74188"
                     /db_xref="MGI:MGI:1921438"
                     /translation="MELQFRQPHFSDALLLLLLSNLLLWEKASSIPACMAEKSGCWNP
                     RMETFDSAIRKAETLRTVSKQFYVELYHNQFSSGKFATLTSKLVRRDEIVFRAASHCH
                     STLTNPPNKGIQYITIEIPEYLKTLINYVGAWISPLFHLVIELSAMKDVPETILSKAK
                     EIEENNRQILRDLRWIITEVYPTSKKKEIFPSWELLSFLKSSSRNSKFLAMFNLSHCL
                     EYDTQFFLFHLRILKCRITGKDC"
     exon            95..273
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /inference="alignment:Splign:2.1.0"
     exon            274..312
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /inference="alignment:Splign:2.1.0"
     exon            313..420
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /inference="alignment:Splign:2.1.0"
     exon            421..600
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /inference="alignment:Splign:2.1.0"
     exon            601..1003
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      908..913
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /note="hexamer: AATAAA"
     polyA_site      939
                     /gene="Prl8a8"
                     /gene_synonym="1600032B14Rik; Ghd14; PLP-C3; PLP-Cgamma;
                     Prlpc3"
                     /note="major polyA site"
ORIGIN      
        1 atataactcc gatgaagcag atctccagag acagaactca tcttgcttag aaactcctca
       61 gtgatggaac tgcaattcag acaacctcac ttctcagatg cactcctgct gctactgttg
      121 tcaaacttgc tgctgtggga gaaagcttca tcaattcctg catgtatggc agaaaagagc
      181 ggctgctgga acccacggat ggaaacattt gacagtgcca tccggaaagc tgaaaccctt
      241 cgtacagttt ctaaacaatt ctatgtagag ctttaccaca accaattctc atctggaaaa
      301 tttgcaactc ttacttccaa actggttcgg cgggatgaga ttgttttcag agctgcatct
      361 cactgccatt ctactctaac aaatccccca aataagggaa ttcaatacat aactattgaa
      421 attccagagt atttaaaaac tttgataaat tatgtgggtg cctggattag ccctctattc
      481 catctagtga ttgaactgag tgccatgaaa gatgtccctg aaactatcct ctcaaaagcc
      541 aaggagattg aagagaacaa cagacaaatt ctgcgtgacc ttaggtggat aatcactgag
      601 gtctatccta cctcaaagaa gaaggaaatt tttcccagct gggaacttct ttcattctta
      661 aaatcaagta gcagaaattc taagtttttg gcaatgttta acctttccca ctgtctagag
      721 tatgatacac agttctttct atttcatcta agaatattga agtgtcgtat aactggaaaa
      781 gattgctaag tgcacattta ccatatctgc tttggagacg ctccacaaaa gttcattgca
      841 gagctgttgc ttttaattgt aaacatttga aaagcatgtg tgggtataat gggtctcttt
      901 aaaaaaaaat aaaaagactc tctttagaaa tgtccaaaat tttaaagctt attcatcttt
      961 tgttcattga atagaacata tattaataaa gttagattta ctc
//
