LOCUS       NM_001271378            1125 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus prolactin family 8, subfamily a, member 6 (Prl8a6),
            transcript variant 1, mRNA.
ACCESSION   NM_001271378
VERSION     NM_001271378.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1125)
  AUTHORS   Roberts,G.A.G. and Tunster,S.J.
  TITLE     Characterising the dynamics of placental glycogen stores in the
            mouse
  JOURNAL   Placenta 99, 131-140 (2020)
   PUBMED   32798765
REFERENCE   2  (bases 1 to 1125)
  AUTHORS   Tunster,S.J., McNamara,G.I., Creeth,H.D.J. and John,R.M.
  TITLE     Increased dosage of the imprinted Ascl2 gene restrains two key
            endocrine lineages of the mouse Placenta
  JOURNAL   Dev Biol 418 (1), 55-65 (2016)
   PUBMED   27542691
REFERENCE   3  (bases 1 to 1125)
  AUTHORS   Tunster,S.J., Creeth,H.D.J. and John,R.M.
  TITLE     The imprinted Phlda2 gene modulates a major endocrine compartment
            of the placenta to regulate placental demands for maternal
            resources
  JOURNAL   Dev Biol 409 (1), 251-260 (2016)
   PUBMED   26476147
REFERENCE   4  (bases 1 to 1125)
  AUTHORS   Premzl,M.
  TITLE     Curated eutherian third party data gene data sets
  JOURNAL   Data Brief 6, 208-213 (2015)
   PUBMED   26862561
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1125)
  AUTHORS   Premzl,M.
  TITLE     Third party data gene data set of eutherian growth hormone genes
  JOURNAL   Genom Data 6, 166-169 (2015)
   PUBMED   26697363
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1125)
  AUTHORS   Knox,K. and Baker,J.C.
  TITLE     Genomic evolution of the placenta using co-option and duplication
            and divergence
  JOURNAL   Genome Res 18 (5), 695-705 (2008)
   PUBMED   18340042
REFERENCE   7  (bases 1 to 1125)
  AUTHORS   Soares,M.J., Alam,S.M., Duckworth,M.L., Horseman,N.D., Konno,T.,
            Linzer,D.I., Maltais,L.J., Nilsen-Hamilton,M., Shiota,K.,
            Smith,J.R. and Wallis,M.
  TITLE     A standardized nomenclature for the mouse and rat prolactin
            superfamilies
  JOURNAL   Mamm Genome 18 (3), 154-156 (2007)
   PUBMED   17476555
REFERENCE   8  (bases 1 to 1125)
  AUTHORS   Li,Y. and Zhang,Y.P.
  TITLE     Molecular evolution of prolactin gene family in rodents
  JOURNAL   Yi Chuan Xue Bao 33 (7), 590-597 (2006)
   PUBMED   16875316
REFERENCE   9  (bases 1 to 1125)
  AUTHORS   Wiemers,D.O., Shao,L.J., Ain,R., Dai,G. and Soares,M.J.
  TITLE     The mouse prolactin gene family locus
  JOURNAL   Endocrinology 144 (1), 313-325 (2003)
   PUBMED   12488360
REFERENCE   10 (bases 1 to 1125)
  AUTHORS   Dai,G., Chapman,B.M., Liu,B., Orwig,K.E., Wang,D., White,R.A.,
            Preuett,B. and Soares,M.J.
  TITLE     A new member of the mouse prolactin (PRL)-like protein-C subfamily,
            PRL-like protein-C alpha: structure and expression
  JOURNAL   Endocrinology 139 (12), 5157-5163 (1998)
   PUBMED   9832456
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005478.1 and AK005435.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005435.1, CF617913.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AK005478.1         2-41
            41-537              AK005435.1         2-498
            538-1125            AK005478.1         434-1021
FEATURES             Location/Qualifiers
     source          1..1125
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 12.45 cM"
     gene            1..1125
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /note="prolactin family 8, subfamily a, member 6"
                     /db_xref="GeneID:19112"
                     /db_xref="MGI:MGI:1332225"
     exon            1..131
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..823
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; prolactin-like protein C 1; prolactin-8A6;
                     PRL-like protein C1; growth hormone d13; prolactin-like
                     protein C-alpha; placental prolactin-like protein C1"
                     /codon_start=1
                     /product="prolactin-8A6 isoform a precursor"
                     /protein_id="NP_001258307.1"
                     /db_xref="CCDS:CCDS70442.1"
                     /db_xref="GeneID:19112"
                     /db_xref="MGI:MGI:1332225"
                     /translation="MALLLSQPHFSGPLLLLVVSNLLLWEKAASNLPCVAEEGGCWNP
                     LLETFNSATQKAETLHNLADQLYVELYYNQFSSGQFWDFSSQIIRQDKTVVRAGSYCH
                     SSLTNPPNTGVHINIEIASYLKTLINFVGSWISPLFHLVIELSATKDVPETILSKAKE
                     IEENNRQILSDLRWILTKVSPAAEMTEEFPHWEYLSFLKSSDKNNKFLAMFNLSYCID
                     HDSKYILLQLRLLKCLITGKDC"
     exon            132..310
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            311..349
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            350..454
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            455..634
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /inference="alignment:Splign:2.1.0"
     exon            635..1125
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      949..954
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /note="hexamer: AATAAA"
     polyA_site      979
                     /gene="Prl8a6"
                     /gene_synonym="Ghd13; PLP-C1; PLP-Ca; PLP-calpha; Prlpc;
                     Prlpc1"
                     /note="major polyA site"
ORIGIN      
        1 atctgctcga ttatatagga acaggaaagt aactgaatat aaaactcctg tgaagcagat
       61 ctgcagacat aggactcatc ctgcttagga actcctaacg atggcactgc tattgagtca
      121 acctcacttc tcaggtccac tcctgctgct ggtggtgtca aatttgctgt tgtgggaaaa
      181 agctgcatca aatcttccat gtgttgcaga agagggtggt tgctggaacc cacttttgga
      241 aacatttaac agtgccaccc agaaagctga aaccctccat aatcttgctg accaattata
      301 tgtagaactt tattacaacc aattctcatc tggacaattt tgggatttta gttctcaaat
      361 aattagacag gataagactg ttgtcagagc tggaagttac tgccattcaa gtctcacgaa
      421 ccccccaaat acaggtgtac acataaatat tgaaatcgca tcatatttaa aaactttgat
      481 caattttgtg ggttcctgga tcagccctct attccatcta gtgattgaac taagtgcaac
      541 aaaagatgtc cctgaaacta tcctctcaaa agccaaggag atcgaagaga acaacagaca
      601 aatcctgagt gaccttaggt ggatactcac caaggtctct cctgcggcag agatgacaga
      661 agaatttccc cactgggaat atctttcatt cttaaaatca agtgacaaaa ataataagtt
      721 tttggcaatg tttaaccttt cctactgcat agatcatgat tcaaagtaca ttttgcttca
      781 gctcagatta ttgaagtgtc tcataactgg gaaagattgc taagtgcaca tacatttacc
      841 atgtctgctt tgaagatgct ccacaaaagt tcattgctga gcagttgtgt ttaattgtat
      901 acatttgaaa tgcttgtgtg gatataatga gtctctttaa aaaaataaaa taaaaacatt
      961 ctctttagaa atatccacat ctaaaatgtc tagccatctt ttgttcattg aatagaatat
     1021 aaatcaataa actcagtttg cctcaatcaa atatatcacc aacaatacat gttaatctag
     1081 caaataatgc taaagtttat ttaaataaaa tcacatttat ttcac
//
