LOCUS       NM_011168               1277 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus prolactin family 7, subfamily a, member 2 (Prl7a2),
            mRNA.
ACCESSION   NM_011168
VERSION     NM_011168.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1277)
  AUTHORS   Roberts,G.A.G. and Tunster,S.J.
  TITLE     Characterising the dynamics of placental glycogen stores in the
            mouse
  JOURNAL   Placenta 99, 131-140 (2020)
   PUBMED   32798765
REFERENCE   2  (bases 1 to 1277)
  AUTHORS   Tunster,S.J., McNamara,G.I., Creeth,H.D.J. and John,R.M.
  TITLE     Increased dosage of the imprinted Ascl2 gene restrains two key
            endocrine lineages of the mouse Placenta
  JOURNAL   Dev Biol 418 (1), 55-65 (2016)
   PUBMED   27542691
REFERENCE   3  (bases 1 to 1277)
  AUTHORS   Tunster,S.J., Creeth,H.D.J. and John,R.M.
  TITLE     The imprinted Phlda2 gene modulates a major endocrine compartment
            of the placenta to regulate placental demands for maternal
            resources
  JOURNAL   Dev Biol 409 (1), 251-260 (2016)
   PUBMED   26476147
REFERENCE   4  (bases 1 to 1277)
  AUTHORS   Premzl,M.
  TITLE     Curated eutherian third party data gene data sets
  JOURNAL   Data Brief 6, 208-213 (2015)
   PUBMED   26862561
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1277)
  AUTHORS   Premzl,M.
  TITLE     Third party data gene data set of eutherian growth hormone genes
  JOURNAL   Genom Data 6, 166-169 (2015)
   PUBMED   26697363
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1277)
  AUTHORS   Simmons,D.G., Rawn,S., Davies,A., Hughes,M. and Cross,J.C.
  TITLE     Spatial and temporal expression of the 23 murine
            Prolactin/Placental Lactogen-related genes is not associated with
            their position in the locus
  JOURNAL   BMC Genomics 9, 352 (2008)
   PUBMED   18662396
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1277)
  AUTHORS   Soares,M.J., Alam,S.M., Duckworth,M.L., Horseman,N.D., Konno,T.,
            Linzer,D.I., Maltais,L.J., Nilsen-Hamilton,M., Shiota,K.,
            Smith,J.R. and Wallis,M.
  TITLE     A standardized nomenclature for the mouse and rat prolactin
            superfamilies
  JOURNAL   Mamm Genome 18 (3), 154-156 (2007)
   PUBMED   17476555
REFERENCE   8  (bases 1 to 1277)
  AUTHORS   Zhou,B., Lum,H.E., Lin,J. and Linzer,D.I.
  TITLE     Two placental hormones are agonists in stimulating megakaryocyte
            growth and differentiation
  JOURNAL   Endocrinology 143 (11), 4281-4286 (2002)
   PUBMED   12399423
  REMARK    GeneRIF: results show that PRL-like proteins E and F have the same
            stimulatory effects on megakaryocyte growth and differentiation
REFERENCE   9  (bases 1 to 1277)
  AUTHORS   Muller,H., Orwig,K.E. and Soares,M.J.
  TITLE     Identification of two new members of the mouse prolactin gene
            family
  JOURNAL   Biochim Biophys Acta 1396 (3), 251-258 (1998)
   PUBMED   9545574
REFERENCE   10 (bases 1 to 1277)
  AUTHORS   Lin,J., Poole,J. and Linzer,D.I.
  TITLE     Two novel members of the prolactin/growth hormone family are
            expressed in the mouse placenta
  JOURNAL   Endocrinology 138 (12), 5535-5540 (1997)
   PUBMED   9389541
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK131665.1.
            
            On Oct 21, 2009 this sequence version replaced NM_011168.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131665.1, AK028068.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-899               AK131665.1         2-900
            900-1277            AK131665.1         903-1280
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 12.58 cM"
     gene            1..1277
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /note="prolactin family 7, subfamily a, member 2"
                     /db_xref="GeneID:19114"
                     /db_xref="MGI:MGI:1206571"
     exon            1..73
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..804
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /note="prolactin-7A2; PRL-like protein F; placental
                     prolactin-like protein F; growth hormone d18"
                     /codon_start=1
                     /product="prolactin-7A2 precursor"
                     /protein_id="NP_035298.1"
                     /db_xref="CCDS:CCDS26404.1"
                     /db_xref="GeneID:19114"
                     /db_xref="MGI:MGI:1206571"
                     /translation="MSFSFSQPCPSGALLLVVVSSLLLWENVASVPLSSNETDGYPLS
                     INGLFHNAMRLTWNIKNLNMELRKTYTVNQVSEKLYENYMLDFIEDMEYLVKALTCCH
                     NYSIKTPENLDEAQQIPFNEFPKLILSRMWAWNETSKVLLTTLRSIPGMHDDVISLAK
                     NIETKLAELFEYTQSILNSIYGTTTTGNVEYTVFSGLEDLKSSDEEFSLFDLCKFSYC
                     LRVDIHMVELYLKLLECVVYVSSDVCLSKNIRDAS"
     exon            74..252
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /inference="alignment:Splign:2.1.0"
     exon            253..291
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /inference="alignment:Splign:2.1.0"
     exon            292..399
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /inference="alignment:Splign:2.1.0"
     exon            400..579
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /inference="alignment:Splign:2.1.0"
     exon            580..1277
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /inference="alignment:Splign:2.1.0"
     regulatory      883..888
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /note="hexamer: AATAAA"
     polyA_site      903
                     /gene="Prl7a2"
                     /gene_synonym="Ghd18; PLP-F; Prlpf"
                     /note="major polyA site"
ORIGIN      
        1 agactgcgtg aagcagacag gctgtgccag aactcttcag agatgtcatt ttctttctct
       61 caaccatgcc cctcaggggc acttctgctg gtggtggtgt caagcctcct tttatgggag
      121 aatgtggcct ctgtaccttt gagtagcaat gagactgatg gttatccatt atccatcaat
      181 gggctgtttc ataatgccat gagactaact tggaatatca aaaacctcaa catggaactg
      241 cgcaagacat atacagtcaa tcaagtctct gaaaaattat acgagaacta tatgcttgac
      301 tttattgagg acatggagta tctggtcaag gctctcacct gctgccacaa ttattccatc
      361 aaaactccag aaaacctgga cgaagctcaa cagattcctt ttaacgaatt tccaaagctg
      421 atcctcagta gaatgtgggc ttggaatgaa acttctaaag ttctactgac cacactcaga
      481 agtattccag gaatgcatga tgatgtcatt tcattagcca aaaacattga aacaaaactt
      541 gcagagcttt ttgagtacac ccagagtata ctcaactcga tttatggaac aacaacaaca
      601 ggaaatgtgg aatacaccgt cttttctggt cttgaagact taaaatcatc tgatgaagaa
      661 tttagtcttt ttgacctttg taaattttcc tattgcttac gtgtagatat acatatggtt
      721 gaactttatc tcaagctatt agagtgtgtg gtatatgtta gtagtgatgt ttgtttatcc
      781 aaaaatatta gagatgcttc atgatgctga atctttttaa ataatcttaa ttttataatt
      841 gtgaaagtat aattgagtat aacgagtgtc ttttaaaata aaaataaact atatatataa
      901 atatatatgt gtatatgtta aaagtttaca aagaaaattt gttactacct tttattcatt
      961 tagtattaaa tgtattaata gctttaagag gaatgacaga caaatggaga atcaaaaaca
     1021 tcagaatcac agtaaattaa tgttaatgtt ggtataatta taagtatcaa atacttaatc
     1081 cataattaaa tgtatttcca tattattaag tagatgggac tattgggata ctgcaagaaa
     1141 gtaattcagt ttgatggaaa ttgtcctatt accctatgct ataaccaccc atcaggtctt
     1201 cgagacaatt aacaccatgt tttgtggttc aatttgtaag actttcccct aatatacaag
     1261 tcacatgtat tcactgt
//
