LOCUS       NM_001164058             977 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus prolactin family 7, subfamily a, member 1 (Prl7a1),
            transcript variant 1, mRNA.
ACCESSION   NM_001164058
VERSION     NM_001164058.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 977)
  AUTHORS   Zietek,M.M., Jaszczyk,A., Stankiewicz,A.M. and Sampino,S.
  TITLE     Prenatal gene-environment interactions mediate the impact of
            advanced maternal age on mouse offspring behavior
  JOURNAL   Sci Rep 14 (1), 31733 (2024)
   PUBMED   39738558
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 977)
  AUTHORS   Zhu,Z., Zou,Q., Wang,C., Li,D., Yang,Y., Xiao,Y., Jin,Y., Yan,J.,
            Luo,L., Sun,Y. and Liang,X.
  TITLE     Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors
            and is Required for Placenta Morphogenesis and Vasculature
            Formation
  JOURNAL   Adv Sci (Weinh) 11 (32), e2400238 (2024)
   PUBMED   38923264
REFERENCE   3  (bases 1 to 977)
  AUTHORS   Roberts,G.A.G. and Tunster,S.J.
  TITLE     Characterising the dynamics of placental glycogen stores in the
            mouse
  JOURNAL   Placenta 99, 131-140 (2020)
   PUBMED   32798765
REFERENCE   4  (bases 1 to 977)
  AUTHORS   Paikari,A., D Belair,C., Saw,D. and Blelloch,R.
  TITLE     The eutheria-specific miR-290 cluster modulates placental growth
            and maternal-fetal transport
  JOURNAL   Development 144 (20), 3731-3743 (2017)
   PUBMED   28935707
REFERENCE   5  (bases 1 to 977)
  AUTHORS   Tunster,S.J., Creeth,H.D.J. and John,R.M.
  TITLE     The imprinted Phlda2 gene modulates a major endocrine compartment
            of the placenta to regulate placental demands for maternal
            resources
  JOURNAL   Dev Biol 409 (1), 251-260 (2016)
   PUBMED   26476147
REFERENCE   6  (bases 1 to 977)
  AUTHORS   Zhou,B., Kong,X. and Linzer,D.I.
  TITLE     Enhanced recovery from thrombocytopenia and neutropenia in mice
            constitutively expressing a placental hematopoietic cytokine
  JOURNAL   Endocrinology 146 (1), 64-70 (2005)
   PUBMED   15375031
REFERENCE   7  (bases 1 to 977)
  AUTHORS   Zhou,B., Lum,H.E., Lin,J. and Linzer,D.I.
  TITLE     Two placental hormones are agonists in stimulating megakaryocyte
            growth and differentiation
  JOURNAL   Endocrinology 143 (11), 4281-4286 (2002)
   PUBMED   12399423
  REMARK    GeneRIF: results show that PRL-like proteins E and F have the same
            stimulatory effects on megakaryocyte growth and differentiation
REFERENCE   8  (bases 1 to 977)
  AUTHORS   Bhattacharyya,S., Lin,J. and Linzer,D.I.
  TITLE     Reactivation of a hematopoietic endocrine program of pregnancy
            contributes to recovery from thrombocytopenia
  JOURNAL   Mol Endocrinol 16 (6), 1386-1393 (2002)
   PUBMED   12040023
  REMARK    GeneRIF: injection of PLP-E into thrombocytopenic mice restores
            normal platelet levels with no effect on granulocytes,
            erythrocytes, and total white blood cell counts
REFERENCE   9  (bases 1 to 977)
  AUTHORS   Muller,H., Orwig,K.E. and Soares,M.J.
  TITLE     Identification of two new members of the mouse prolactin gene
            family
  JOURNAL   Biochim Biophys Acta 1396 (3), 251-258 (1998)
   PUBMED   9545574
REFERENCE   10 (bases 1 to 977)
  AUTHORS   Lin,J., Poole,J. and Linzer,D.I.
  TITLE     Two novel members of the prolactin/growth hormone family are
            expressed in the mouse placenta
  JOURNAL   Endocrinology 138 (12), 5535-5540 (1997)
   PUBMED   9389541
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK146050.1, AF011381.1 and BC051671.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146050.1, AF020525.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-409               AK146050.1         2-410
            410-944             AF011381.1         399-933
            945-977             BC051671.1         927-959
FEATURES             Location/Qualifiers
     source          1..977
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 12.56 cM"
     gene            1..977
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /note="prolactin family 7, subfamily a, member 1"
                     /db_xref="GeneID:19113"
                     /db_xref="MGI:MGI:1206572"
     exon            1..74
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..844
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; prolactin-7A1; PRL-like protein E; PRL-like
                     protein G; placental prolactin-like protein E; placental
                     prolactin-like protein G"
                     /codon_start=1
                     /product="prolactin-7A1 isoform 1 precursor"
                     /protein_id="NP_001157530.1"
                     /db_xref="CCDS:CCDS49224.1"
                     /db_xref="GeneID:19113"
                     /db_xref="MGI:MGI:1206572"
                     /translation="MPLSFTQPCSSGALLLLVVSNLLLWENVACLPLSSNDTDDDPLS
                     IKGLLDHAMILSKNITDLNMELRRIFTISEMSAKLIDKFLSSSSSSDSYDQFMLEFLG
                     QQELLTKNLTYCHKYSIKVPEDIEEAQNVISLEDFPILILSRMQAWNETLKNRINLSE
                     GTPGIDDDILPIYKNIETKIAELLEDSKSILSQAYGATENVADYTLWSGLEDLQSSDE
                     ETRFLALCKLSYCLHVDIHTANFYLQFLRCVALVNSDSCLSSKTGNDS"
     exon            75..253
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
     exon            254..292
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
     exon            293..331
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
     exon            332..442
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
     exon            443..622
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
     exon            623..959
                     /gene="Prl7a1"
                     /gene_synonym="PLP-E; PLP-G; Prlpe; Prlpg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggactgcg agaaaaagac aagtgtgcaa ggacacctca gagatgccgc tgtctttcac
       61 tcaaccatgc tcctcagggg cacttctgct gctggtggtg tcaaacctcc ttttatggga
      121 gaatgtggcc tgtctacctt taagcagcaa tgatactgat gatgatccac tatccatcaa
      181 gggactgttg gatcatgcca tgatactttc taagaatatc actgacctca acatggagtt
      241 gcgcaggata tttaccatca gtgagatgtc agctaaactt attgataaat ttctaagttc
      301 atcatcatca tcagactcct atgatcaatt tatgcttgaa tttcttgggc agcaggagtt
      361 actgactaag aacctcacct actgccacaa atactccatc aaagttcccg aagacataga
      421 agaagcccaa aatgtcatct ctcttgaaga ctttccaatc ttgatactca gtagaatgca
      481 ggcttggaat gaaactctga aaaaccgaat caacctatct gaaggtacac caggaataga
      541 cgatgatatc ctccctatat ataaaaatat tgagacaaaa attgcagaac ttcttgagga
      601 cagcaagagt atactcagcc aggcttatgg agcaacagaa aatgtggctg attacaccct
      661 ctggtctggt cttgaagacc ttcaatcatc tgatgaagaa actcgatttt tggctctttg
      721 taaattatcc tattgtttgc atgttgatat ccacacagct aacttttatc tccagttctt
      781 gaggtgtgtg gctcttgtta atagtgacag ctgcttatct tccaaaactg gaaatgattc
      841 atgatgctgt attattttaa aatagtctga ttttatgcat ttcaaagatg agcatgagta
      901 aaatgggcat cttttaaaag aaaaataaac attgtgtgtt taacaaagtt ttaaaaatta
      961 aaaaaaaaaa aaaaaaa
//
