LOCUS       NM_001361097             868 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus prolactin family 3, subfamily d, member 3 (Prl3d3),
            transcript variant 2, mRNA.
ACCESSION   NM_001361097 XM_006516640
VERSION     NM_001361097.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Bao H, Liu D, Xu Y, Sun Y, Mu C, Yu Y, Wang C, Han Q, Liu S, Cai H,
            Liu F, Kong S, Deng W, Cao B, Wang H, Wang Q and Lu J.
  TITLE     Hyperactivated Wnt-beta-catenin signaling in the absence of sFRP1
            and sFRP5 disrupts trophoblast differentiation through repression
            of Ascl2
  JOURNAL   BMC Biol 18 (1), 151 (2020)
   PUBMED   33109217
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  AUTHORS   Premzl M.
  TITLE     Curated eutherian third party data gene data sets
  JOURNAL   Data Brief 6, 208-213 (2015)
   PUBMED   26862561
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 868)
  AUTHORS   Premzl M.
  TITLE     Third party data gene data set of eutherian growth hormone genes
  JOURNAL   Genom Data 6, 166-169 (2015)
   PUBMED   26697363
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 868)
  AUTHORS   Chen X, Hausman BS, Luo G, Zhou G, Murakami S, Rubin J and
            Greenfield EM.
  TITLE     Protein kinase inhibitor gamma reciprocally regulates osteoblast
            and adipocyte differentiation by downregulating leukemia inhibitory
            factor
  JOURNAL   Stem Cells 31 (12), 2789-2799 (2013)
   PUBMED   23963683
  REMARK    GeneRIF: Results show that endogenous levels of Pkig reciprocally
            regulate osteoblast and adipocyte differentiation and that this
            reciprocal regulation is mediated in part by LIF.
REFERENCE   5  (bases 1 to 868)
  AUTHORS   Hayakawa K, Nakanishi MO, Ohgane J, Tanaka S, Hirosawa M, Soares
            MJ, Yagi S and Shiota K.
  TITLE     Bridging sequence diversity and tissue-specific expression by DNA
            methylation in genes of the mouse prolactin superfamily
  JOURNAL   Mamm Genome 23 (5-6), 336-345 (2012)
   PUBMED   22193412
REFERENCE   6  (bases 1 to 868)
  AUTHORS   Bondareva AA, Capecchi MR, Iverson SV, Li Y, Lopez NI, Lucas O,
            Merrill GF, Prigge JR, Siders AM, Wakamiya M, Wallin SL and Schmidt
            EE.
  TITLE     Effects of thioredoxin reductase-1 deletion on embryogenesis and
            transcriptome
  JOURNAL   Free Radic Biol Med 43 (6), 911-923 (2007)
   PUBMED   17697936
REFERENCE   7  (bases 1 to 868)
  AUTHORS   Soares,M.J., Alam,S.M., Duckworth,M.L., Horseman,N.D., Konno,T.,
            Linzer,D.I., Maltais,L.J., Nilsen-Hamilton,M., Shiota,K.,
            Smith,J.R. and Wallis,M.
  TITLE     A standardized nomenclature for the mouse and rat prolactin
            superfamilies
  JOURNAL   Mamm Genome 18 (3), 154-156 (2007)
   PUBMED   17476555
REFERENCE   8  (bases 1 to 868)
  AUTHORS   Takeda K, Ho VC, Takeda H, Duan LJ, Nagy A and Fong GH.
  TITLE     Placental but not heart defects are associated with elevated
            hypoxia-inducible factor alpha levels in mice lacking prolyl
            hydroxylase domain protein 2
  JOURNAL   Mol Cell Biol 26 (22), 8336-8346 (2006)
   PUBMED   16966370
REFERENCE   9  (bases 1 to 868)
  AUTHORS   Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco
            G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T,
            Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T,
            Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ,
            Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A,
            Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso
            J, Hide W and Ko MS.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   10 (bases 1 to 868)
  AUTHORS   Wiemers DO, Shao LJ, Ain R, Dai G and Soares MJ.
  TITLE     The mouse prolactin gene family locus
  JOURNAL   Endocrinology 144 (1), 313-325 (2003)
   PUBMED   12488360
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN691496.1, LM644173.1 and BC068253.1.
            
            On Mar 1, 2018 this sequence version replaced XM_006516640.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: LM644173.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                CN691496.1         1-43
            44-718              LM644173.1         1-675
            719-868             BC068253.1         708-857
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 12.3 cM"
     gene            1..868
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /note="prolactin family 3, subfamily d, member 3"
                     /db_xref="GeneID:215029"
                     /db_xref="MGI:MGI:2660938"
     exon            1..74
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..718
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; PL-1 gamma; placental lactogen I gamma; growth
                     hormone d6"
                     /codon_start=1
                     /product="prolactin family 3, subfamily d, member 3
                     isoform 2 precursor"
                     /protein_id="NP_001348026.1"
                     /db_xref="CCDS:CCDS88430.1"
                     /db_xref="GeneID:215029"
                     /db_xref="MGI:MGI:2660938"
                     /translation="MQLTLTLSGSAGMQLLLLVSSLFLWENVSSKPTAMVPTEDLYTR
                     LAELSHSTFILAADVYREFDLDFFDKTWITDRTLPLCHTASIHTPENREEVHEIKTED
                     LLKAMINVSISWKEPLKHLVSALTALPGASESMGKKAADIKGRNLIILEGLQTIYNRT
                     QANIEENENFDYPAWSGLEELQSPNEDTHLFAVYNLCRCIKRDIHKIDSYIKVLRCRV
                     VFQNEC"
     exon            75..232
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /inference="alignment:Splign:2.1.0"
     exon            233..340
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /inference="alignment:Splign:2.1.0"
     exon            341..520
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /inference="alignment:Splign:2.1.0"
     exon            521..855
                     /gene="Prl3d3"
                     /gene_synonym="Ghd6; PL-Ig; Plig"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttcctcac ttggagccta cattgtggtg gatcttctca gaaatgcagc tgactttgac
       61 tctttcaggc tccgcaggaa tgcaattgtt gctgctggtg tcaagcctat tcctttggga
      121 gaatgtgtcc tccaaaccaa ctgccatggt gcccactgaa gacctgtata ctcgtttggc
      181 tgaactgtct catagtacat ttatcttggc cgcagatgtg tatagggaat ttgatttgga
      241 ttttttcgat aaaacttgga taacagacag aacacttccc ctgtgtcata ctgcttccat
      301 ccatactcca gagaatcgag aggaagtcca tgaaattaaa actgaagacc ttctgaaagc
      361 aatgatcaat gtttcaattt cctggaaaga acctctgaaa cacctggtgt ctgcactgac
      421 tgctcttcca ggagcttctg agagtatggg gaaaaaagct gctgacatta agggcagaaa
      481 ccttataatt ctggagggac ttcagacaat atacaacagg actcaggcta acattgaaga
      541 aaatgaaaat tttgactacc ctgcttggtc tggactcgaa gaactgcagt cacctaatga
      601 agacactcat ctttttgccg tttataacct atgccgctgc attaaaaggg acatccataa
      661 gatagacagc tatatcaaag tcttgaggtg ccgagttgtc tttcagaacg aatgttgagt
      721 gcccacccag caaagccctg cccacatggt ctttgttgat ccagacttgt aatgctttcc
      781 cctcctcagt tatgtagagc tataatggaa ttattgtaat aaaataaaat aaatttattt
      841 agattcaatg tgaaaaaaaa aaaaaaaa
//
