LOCUS       NM_008864                875 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus prolactin family 3, subfamily d, member 1 (Prl3d1),
            transcript variant 2, mRNA.
ACCESSION   NM_008864
VERSION     NM_008864.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Zhu,Z., Zou,Q., Wang,C., Li,D., Yang,Y., Xiao,Y., Jin,Y., Yan,J.,
            Luo,L., Sun,Y. and Liang,X.
  TITLE     Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors
            and is Required for Placenta Morphogenesis and Vasculature
            Formation
  JOURNAL   Adv Sci (Weinh) 11 (32), e2400238 (2024)
   PUBMED   38923264
REFERENCE   2  (bases 1 to 875)
  AUTHORS   Yang,N., Sun,Y., Han,B., Deng,N., Li,G., Han,Q., Wang,Y., Cai,H.,
            Liu,F., Cao,B., Deng,W., Bao,H., Kong,S., Lu,J. and Wang,H.
  TITLE     Trophoblastic signals facilitate endometrial interferon response
            and lipid metabolism, ensuring normal decidualization
  JOURNAL   Cell Rep 43 (6), 114246 (2024)
   PUBMED   38762885
REFERENCE   3  (bases 1 to 875)
  AUTHORS   Lee,J.G., Yon,J.M., Kim,G., Lee,S.G., Kim,C.Y., Cheong,S.A.,
            Kim,H.Y., Yu,J., Kim,K., Sung,Y.H., Yoo,H.J., Woo,D.C., Rho,J.K.,
            Ha,C.H., Pack,C.G., Oh,S.H., Lim,J.S., Han,Y.M., Hong,E.J.,
            Seong,J.K., Lee,H.W., Lee,S.W., Lee,K.U., Kim,C.J., Nam,S.Y.,
            Cho,Y.S. and Baek,I.J.
  TITLE     PIBF1 regulates trophoblast syncytialization and promotes
            cardiovascular development
  JOURNAL   Nat Commun 15 (1), 1487 (2024)
   PUBMED   38374152
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 875)
  AUTHORS   Astrof,S., Arriagada,C., Saijoh,Y., Francou,A., Kelly,R.G. and
            Moon,A.
  TITLE     Aberrant differentiation of second heart field mesoderm prefigures
            cellular defects in the outflow tract in response to loss of FGF8
  JOURNAL   Dev Biol 499, 10-21 (2023)
   PUBMED   37060937
REFERENCE   5  (bases 1 to 875)
  AUTHORS   Singh,V.P., Hassan,H., Deng,F., Tsuchiya,D., McKinney,S., Ferro,K.
            and Gerton,J.L.
  TITLE     Myc promotes polyploidy in murine trophoblast cells and suppresses
            senescence
  JOURNAL   Development 150 (11) (2023)
   PUBMED   37278344
REFERENCE   6  (bases 1 to 875)
  AUTHORS   Yamaguchi,M., Ogren,L., Kurachi,H., Hirota,K., Imai,T. and
            Talamantes,F.
  TITLE     Opposite effects of transforming growth factor alpha and epidermal
            growth factor on mouse placental lactogen I secretion
  JOURNAL   Proc Natl Acad Sci U S A 92 (7), 2830-2834 (1995)
   PUBMED   7535931
REFERENCE   7  (bases 1 to 875)
  AUTHORS   Strauss,B.L., Pittman,R., Pixley,M.R., Nilson,J.H. and Boime,I.
  TITLE     Expression of the beta subunit of chorionic gonadotropin in
            transgenic mice
  JOURNAL   J Biol Chem 269 (7), 4968-4973 (1994)
   PUBMED   7508931
REFERENCE   8  (bases 1 to 875)
  AUTHORS   Faria,T.N., Ogren,L., Talamantes,F., Linzer,D.I. and Soares,M.J.
  TITLE     Localization of placental lactogen-I in trophoblast giant cells of
            the mouse placenta
  JOURNAL   Biol Reprod 44 (2), 327-331 (1991)
   PUBMED   2009333
REFERENCE   9  (bases 1 to 875)
  AUTHORS   Jackson-Grusby,L.L., Pravtcheva,D., Ruddle,F.H. and Linzer,D.I.
  TITLE     Chromosomal mapping of the prolactin/growth hormone gene family in
            the mouse
  JOURNAL   Endocrinology 122 (6), 2462-2466 (1988)
   PUBMED   2836164
REFERENCE   10 (bases 1 to 875)
  AUTHORS   Colosi,P., Talamantes,F. and Linzer,D.I.
  TITLE     Molecular cloning and expression of mouse placental lactogen I
            complementary deoxyribonucleic acid
  JOURNAL   Mol Endocrinol 1 (11), 767-776 (1987)
   PUBMED   3153461
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591843.14, AK082929.1 and CJ214787.1.
            
            On Apr 15, 2011 this sequence version replaced NM_008864.2.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 3' coding region, compared to variant 1. This
            results in a shorter protein (isoform 2), compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK082929.1, BC064736.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN02146468
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AL591843.14        88220-88220
            2-864               AK082929.1         1-863
            865-875             CJ214787.1         362-372
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 12.27 cM"
     gene            1..875
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /note="prolactin family 3, subfamily d, member 1"
                     /db_xref="GeneID:18775"
                     /db_xref="MGI:MGI:97606"
     exon            1..95
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..736
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; chorionic somatomammotropin hormone 1;
                     prolactin-3D1; placental lactogen-I alpha; placental
                     lactogen I; prolactin-like 2; placental lactogen 1; growth
                     hormone d4"
                     /codon_start=1
                     /product="prolactin-3D1 isoform 2 precursor"
                     /protein_id="NP_032890.2"
                     /db_xref="CCDS:CCDS88428.1"
                     /db_xref="GeneID:18775"
                     /db_xref="MGI:MGI:97606"
                     /translation="MQLTLNLSGSGMQLLLLVSSLLLWENVSSKPTAMVPTEDLYTRL
                     AELSHNTFILAADVYREFDLDFFDKTWITDRTLPLCHTASIHTPENREEVHETKTEDL
                     LKAMINVSISWKEPLKHLVSALTALPGASESMGKKAADIKGRNLVILEGLQTIYNRTQ
                     ANIEENENFDYPAWSGLEELQSPNEDTHLFAVYNLCRCIKRDIHKIDSYIKVLRCRVV
                     FQNEC"
     exon            96..250
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /inference="alignment:Splign:2.1.0"
     exon            251..358
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /inference="alignment:Splign:2.1.0"
     exon            359..538
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /inference="alignment:Splign:2.1.0"
     exon            539..875
                     /gene="Prl3d1"
                     /gene_synonym="Csh1; Ghd4; mPL-I; Pl-1; PL-I; PL-I-alpha;
                     PL-Ia; Pl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgaacactc aggtgaagca gatttcctca cttggagcct acattgtggt ggatcttctc
       61 agaaatgcag ctgactttga atctttcagg ctccggaatg caattgttgc tgctggtgtc
      121 aagcctactc ctttgggaga atgtgtcctc caaaccaact gccatggtgc ccactgaaga
      181 cctgtatact cgtttggctg aactgtctca taatacattt atcttggccg cagatgtgta
      241 tagggaattt gatttggatt ttttcgataa aacttggata acagacagaa cacttcccct
      301 gtgtcatact gcttccatcc atactccaga gaatcgagag gaagtccacg aaactaaaac
      361 tgaagacctt ctgaaagcaa tgatcaatgt ttcaatttcc tggaaagaac ctctgaaaca
      421 cctggtgtct gcactgacgg ctctcccagg agcttctgag agtatgggga aaaaagctgc
      481 tgacattaag ggcagaaacc ttgtaattct ggagggactt cagacaatat acaacaggac
      541 tcaggctaac attgaagaaa atgaaaattt tgactaccct gcttggtctg gactcgaaga
      601 actgcagtca cctaatgaag acactcatct ttttgccgtt tataatctat gccgctgcat
      661 taaaagggac atccataaga tagacagcta tatcaaagtc ttgaggtgcc gagttgtctt
      721 tcagaacgaa tgttgagtgc ccacccagcg aagccctgcc cacatggtct ttgttgaacc
      781 agacttgtaa tgctttcccc tcctcagtta tgtagagcta taatggaatt attgtcataa
      841 aataaaataa aattatttag attcaatgtg aaatt
//
