LOCUS       NM_011118                868 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus prolactin family 2, subfamily c, member 3 (Prl2c3),
            mRNA.
ACCESSION   NM_011118 XM_001005339 XM_976552
VERSION     NM_011118.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Premzl,M.
  TITLE     Curated eutherian third party data gene data sets
  JOURNAL   Data Brief 6, 208-213 (2015)
   PUBMED   26862561
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  AUTHORS   Premzl,M.
  TITLE     Third party data gene data set of eutherian growth hormone genes
  JOURNAL   Genom Data 6, 166-169 (2015)
   PUBMED   26697363
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 868)
  AUTHORS   Hayakawa,K., Nakanishi,M.O., Ohgane,J., Tanaka,S., Hirosawa,M.,
            Soares,M.J., Yagi,S. and Shiota,K.
  TITLE     Bridging sequence diversity and tissue-specific expression by DNA
            methylation in genes of the mouse prolactin superfamily
  JOURNAL   Mamm Genome 23 (5-6), 336-345 (2012)
   PUBMED   22193412
REFERENCE   4  (bases 1 to 868)
  AUTHORS   Simmons,D.G., Rawn,S., Davies,A., Hughes,M. and Cross,J.C.
  TITLE     Spatial and temporal expression of the 23 murine
            Prolactin/Placental Lactogen-related genes is not associated with
            their position in the locus
  JOURNAL   BMC Genomics 9, 352 (2008)
   PUBMED   18662396
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 868)
  AUTHORS   Soares,M.J., Alam,S.M., Duckworth,M.L., Horseman,N.D., Konno,T.,
            Linzer,D.I., Maltais,L.J., Nilsen-Hamilton,M., Shiota,K.,
            Smith,J.R. and Wallis,M.
  TITLE     A standardized nomenclature for the mouse and rat prolactin
            superfamilies
  JOURNAL   Mamm Genome 18 (3), 154-156 (2007)
   PUBMED   17476555
REFERENCE   6  (bases 1 to 868)
  AUTHORS   Choong,M.L., Tan,A.C., Luo,B. and Lodish,H.F.
  TITLE     A novel role for proliferin-2 in the ex vivo expansion of
            hematopoietic stem cells
  JOURNAL   FEBS Lett 550 (1-3), 155-162 (2003)
   PUBMED   12935903
REFERENCE   7  (bases 1 to 868)
  AUTHORS   Wiemers,D.O., Shao,L.J., Ain,R., Dai,G. and Soares,M.J.
  TITLE     The mouse prolactin gene family locus
  JOURNAL   Endocrinology 144 (1), 313-325 (2003)
   PUBMED   12488360
REFERENCE   8  (bases 1 to 868)
  AUTHORS   Ko,M.S., Wang,X., Horton,J.H., Hagen,M.D., Takahashi,N., Maezaki,Y.
            and Nadeau,J.H.
  TITLE     Genetic mapping of 40 cDNA clones on the mouse genome by PCR
  JOURNAL   Mamm Genome 5 (6), 349-355 (1994)
   PUBMED   8043949
REFERENCE   9  (bases 1 to 868)
  AUTHORS   Connor,A.M., Waterhouse,P., Khokha,R. and Denhardt,D.T.
  TITLE     Characterization of a mouse mitogen-regulated protein/proliferin
            gene and its promoter: a member of the growth hormone/prolactin
            gene superfamily
  JOURNAL   Biochim Biophys Acta 1009 (1), 75-82 (1989)
   PUBMED   2790033
REFERENCE   10 (bases 1 to 868)
  AUTHORS   Linzer,D.I., Lee,S.J., Ogren,L., Talamantes,F. and Nathans,D.
  TITLE     Identification of proliferin mRNA and protein in mouse placenta
  JOURNAL   Proc Natl Acad Sci U S A 82 (13), 4356-4359 (1985)
   PUBMED   3859868
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK164068.1 and BU755317.1.
            
            On Jul 14, 2009 this sequence version replaced NM_011118.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145995.1, CF617868.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-825               AK164068.1         2-826
            826-868             BU755317.1         1-43                c
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13"
     gene            1..868
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /note="prolactin family 2, subfamily c, member 3"
                     /db_xref="GeneID:18812"
                     /db_xref="MGI:MGI:1341833"
     exon            1..98
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..742
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /note="prolactin-2C3; prolactin-2C4; proliferin-2;
                     proliferin-3; mitogen-regulated protein 2;
                     mitogen-regulated protein 3; growth hormone d1"
                     /codon_start=1
                     /product="prolactin-2C3 precursor"
                     /protein_id="NP_035248.2"
                     /db_xref="CCDS:CCDS36595.1"
                     /db_xref="GeneID:18812"
                     /db_xref="MGI:MGI:1341833"
                     /translation="MLPSSIQPCSWILLLLLVNSSLLWKNVASFPMCAMRNGRCFMSF
                     EDTFELAGSLSHNISIEVSELFNEFEKHYSNVSGLRDKSPMRCNTSFLPTPENKEQAR
                     LTHYAALLKSGAMILDAWESPLDDLVSELSTIKNVPDIIISKATDIKKKINAVRNGVN
                     ALMSTMLQNGDEEKKNPAWFLQSDNEDARIHSLYGMISCLDNDFKKVDIYLNVLKCYM
                     LKIDNC"
     exon            99..274
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            275..382
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            383..565
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /inference="alignment:Splign:2.1.0"
     exon            566..852
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      829..834
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /note="hexamer: AATAAA"
     polyA_site      852
                     /gene="Prl2c3"
                     /gene_synonym="Ghd1; MRP-2; MRP-3; mrp/plf3; Mrpplf3;
                     PLF-2; PLF-3; Plf2; Prl2c4"
                     /note="major polyA site"
ORIGIN      
        1 aggcttccaa ctccagtaaa gcatcttccc ggaatccaca gctaagcctg ggtaggactc
       61 tgcagagatg ctcccttctt cgattcaacc atgctcctgg atactgctcc tactactggt
      121 gaacagctcg ttattgtgga agaatgttgc ctcatttccc atgtgtgcaa tgaggaatgg
      181 tcgttgcttt atgtcctttg aagacacatt tgaattagcc ggcagtttgt ctcataatat
      241 cagtatagaa gtttcagaac tgttcaatga atttgaaaaa cattattcta acgtgtctgg
      301 gctcagagac aaaagcccca tgagatgcaa tacttctttc cttccaactc cagaaaacaa
      361 ggaacaagcc aggctcacac actatgcagc tcttctgaaa tcaggagcca tgattttgga
      421 tgcctgggaa agccctctgg acgatctagt gagtgaatta tctaccataa aaaatgtccc
      481 tgatataatc atctccaaag ccacagacat aaagaaaaag atcaacgcag tccggaacgg
      541 ggttaatgcc ctcatgagca ccatgcttca gaatggagat gaagaaaaga agaaccctgc
      601 ctggttcttg caatctgaca atgaagatgc tcgcattcat tctttatatg gcatgatcag
      661 ctgcctagac aatgacttta agaaggttga tatttatctc aacgtcctga agtgttacat
      721 gttaaaaata gataactgct gatatttctt tcatgtgctc tgcttctgaa atatcatgta
      781 atatcctttc aatttgtatc ttttgaattt gttgttgact catttaaaaa taaaaagtag
      841 ctctcagaaa taaaaaaaaa aaaaaaaa
//
