LOCUS       NM_011101               8385 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus protein kinase C, alpha (Prkca), mRNA.
ACCESSION   NM_011101
VERSION     NM_011101.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8385)
  AUTHORS   Nord,C., Jones,I., Garcia-Maestre,M., Hagglund,A.C. and Carlsson,L.
  TITLE     Reduced mTORC1-signaling in progenitor cells leads to retinal
            lamination deficits
  JOURNAL   Dev Dyn 253 (10), 922-939 (2024)
   PUBMED   38546215
REFERENCE   2  (bases 1 to 8385)
  AUTHORS   Xu,Y., Cohen,E., Johnson,C.N., Parent,C.A. and Coulombe,P.A.
  TITLE     Repeated stress to the skin amplifies neutrophil infiltration in a
            keratin 17- and PKCalpha-dependent manner
  JOURNAL   PLoS Biol 22 (8), e3002779 (2024)
   PUBMED   39159283
  REMARK    GeneRIF: Repeated stress to the skin amplifies neutrophil
            infiltration in a keratin 17- and PKCalpha-dependent manner.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8385)
  AUTHORS   Zhu,L., Su,W., Xu,X., Shao,S., Qin,C., Gao,R., Wang,X., Ma,M.,
            Gao,J. and Zhang,Z.
  TITLE     Sphincter of Oddi Dysfunction Induces Gallstone by Inhibiting the
            Expression of ABCB11 via PKC-alpha
  JOURNAL   Appl Biochem Biotechnol 196 (8), 5373-5390 (2024)
   PUBMED   38158489
  REMARK    GeneRIF: Sphincter of Oddi Dysfunction Induces Gallstone by
            Inhibiting the Expression of ABCB11 via PKC-alpha.
REFERENCE   4  (bases 1 to 8385)
  AUTHORS   Pang,L., Cui,M., Wu,S. and Kong,J.
  TITLE     Cav-1 regulates the bile salt export pump on the canalicular
            membrane of hepatocytes by PKCalpha-associated signalling under
            cholesterol stimulation
  JOURNAL   J Cell Mol Med 28 (3), e18110 (2024)
   PUBMED   38164042
  REMARK    GeneRIF: Cav-1 regulates the bile salt export pump on the
            canalicular membrane of hepatocytes by PKCalpha-associated
            signalling under cholesterol stimulation.
REFERENCE   5  (bases 1 to 8385)
  AUTHORS   Li,Y., Xiao,D., Chen,H., Zheng,X.F.S. and Xiang,M.
  TITLE     Maf1 controls retinal neuron number by both RNA Pol III- and Pol
            II-dependent mechanisms
  JOURNAL   iScience 26 (12), 108544 (2023)
   PUBMED   38089586
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8385)
  AUTHORS   Stetler-Stevenson,W.G., Liotta,L.A. and Seldin,M.F.
  TITLE     Linkage analysis demonstrates that the Timp-2 locus is on mouse
            chromosome 11
  JOURNAL   Genomics 14 (3), 828-829 (1992)
   PUBMED   1427919
REFERENCE   7  (bases 1 to 8385)
  AUTHORS   Wilkie,T.M., Gilbert,D.J., Olsen,A.S., Chen,X.N., Amatruda,T.T.,
            Korenberg,J.R., Trask,B.J., de Jong,P., Reed,R.R., Simon,M.I. et
            al.
  TITLE     Evolution of the mammalian G protein alpha subunit multigene family
  JOURNAL   Nat Genet 1 (2), 85-91 (1992)
   PUBMED   1302014
  REMARK    Review article
REFERENCE   8  (bases 1 to 8385)
  AUTHORS   Wada,H., Ohno,S., Kubo,K., Taya,C., Tsuji,S., Yonehara,S. and
            Suzuki,K.
  TITLE     Cell type-specific expression of the genes for the protein kinase C
            family: down regulation of mRNAs for PKC alpha and nPKC epsilon
            upon in vitro differentiation of a mouse neuroblastoma cell line
            neuro 2a
  JOURNAL   Biochem Biophys Res Commun 165 (1), 533-538 (1989)
   PUBMED   2590242
REFERENCE   9  (bases 1 to 8385)
  AUTHORS   Buchberg,A.M., Brownell,E., Nagata,S., Jenkins,N.A. and
            Copeland,N.G.
  TITLE     A comprehensive genetic map of murine chromosome 11 reveals
            extensive linkage conservation between mouse and human
  JOURNAL   Genetics 122 (1), 153-161 (1989)
   PUBMED   2567264
REFERENCE   10 (bases 1 to 8385)
  AUTHORS   Rose-John,S., Dietrich,A. and Marks,F.
  TITLE     Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss
            3T3 fibroblasts
  JOURNAL   Gene 74 (2), 465-471 (1988)
   PUBMED   2469625
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147084.1, AL645535.16 and BF455952.1.
            
            On Jan 12, 2008 this sequence version replaced NM_011101.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147084.1, SRR14777535.887346.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2504              AK147084.1         2-2505
            2505-8110           AL645535.16        81380-86985         c
            8111-8385           BF455952.1         1-275               c
FEATURES             Location/Qualifiers
     source          1..8385
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 70.8 cM"
     gene            1..8385
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /note="protein kinase C, alpha"
                     /db_xref="GeneID:18750"
                     /db_xref="MGI:MGI:97595"
     exon            1..394
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..2240
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /EC_number="2.7.11.13"
                     /note="protein kinase c-alpha; PKC-A; PKC-alpha"
                     /codon_start=1
                     /product="protein kinase C alpha type"
                     /protein_id="NP_035231.2"
                     /db_xref="CCDS:CCDS25573.1"
                     /db_xref="GeneID:18750"
                     /db_xref="MGI:MGI:97595"
                     /translation="MADVYPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFF
                     KQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKH
                     KFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRG
                     RIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRST
                     LNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYK
                     LLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRV
                     KLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLA
                     LLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIG
                     LFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPE
                     IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAV
                     SICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAE
                     NFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV"
     exon            395..426
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            427..509
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            510..621
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            622..750
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            751..907
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1042
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1139
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..1277
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1451
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1543
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1606
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1745
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1826
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..1934
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            1935..2075
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     exon            2076..8369
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3486..3491
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /note="hexamer: AATAAA"
     polyA_site      3512
                     /gene="Prkca"
                     /gene_synonym="Pkca"
     regulatory      8346..8351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /note="hexamer: AATAAA"
     polyA_site      8369
                     /gene="Prkca"
                     /gene_synonym="Pkca"
                     /note="major polyA site"
ORIGIN      
        1 agtgagcgtg gggccagcca gcgagccaga gagccggaga gagccagaga gagcggctcg
       61 gctcccagct ccgagtagcg cagcgcccgc ccggctctcc cgggccaccg ccgccaccac
      121 cgcacctcat cagcaccgcc acctcggccg ccgcccccgc ccaccccggc cctccccggc
      181 tgctgctccc cggcggaggc aagaggtggt tggggggaac catggctgac gtttacccgg
      241 ccaacgactc cacggcgtct caggacgtgg ccaaccgctt cgcccgcaaa ggggcgctga
      301 ggcagaagaa cgtgcatgag gtgaaagacc acaaattcat cgcccgcttc ttcaagcaac
      361 ccaccttctg cagccactgc accgacttca tctgggggtt tgggaaacaa ggcttccagt
      421 gccaagtttg ctgttttgtg gttcataaga ggtgccatga gttcgttacg ttctcttgtc
      481 cgggtgcgga taagggacct gacactgacg accccaggag caagcacaag ttcaaaatcc
      541 acacatacgg aagccctacc ttctgtgatc actgtgggtc cctgctctat ggacttatcc
      601 accaagggat gaaatgtgac acctgcgaca tgaatgttca caagcagtgt gtgatcaatg
      661 tccctagcct ctgcggaatg gatcacacag agaagagggg gcggatttat ctgaaggctg
      721 aggtcactga tgaaaagctc cacgtcacgg tacgagatgc aaaaaatcta atccctatgg
      781 atccaaatgg gctttcggat ccttatgtga agctgaaact tatccctgac cccaagaatg
      841 agagcaaaca gaaaaccaaa accatccgct ccacactgaa tcctcagtgg aatgagtcct
      901 tcacgttcaa attaaaacct tcagacaaag accggcgact gtctgtagaa atctgggact
      961 gggatcggac gactcggaat gacttcatgg gatccctttc ctttggtgtc tcagagctaa
     1021 tgaagatgcc ggccagtgga tggtataaac tgctcaacca agaagagggc gaatactaca
     1081 atgtgcccat tccagaagga gatgaagaag gcaacatgga actcaggcag aagtttgaga
     1141 aagccaagct aggccctgct ggtaacaaag tcatcagccc ttcagaagac agaaagcaac
     1201 catccaacaa cctggacaga gtgaaactca cagacttcaa cttcctcatg gtgctgggga
     1261 aggggagttt tgggaaggtg atgcttgctg acaggaaggg aacggaggaa ctgtacgcca
     1321 tcaagatcct gaagaaggac gtggtgatcc aggacgacga cgtggagtgc accatggtgg
     1381 agaagcgcgt gctggccctg ctggacaagc cgccatttct gacacagctg cactcctgct
     1441 tccagacagt ggaccggctg tacttcgtca tggaatacgt caacggcggg gacctcatgt
     1501 accacattca gcaagtcggg aaatttaagg agccacaagc agtattctac gcagccgaga
     1561 tctccatcgg actgttcttc cttcataaaa gagggatcat ttacagggat ctgaagctgg
     1621 acaatgtcat gctggactca gaagggcaca tcaaaatcgc cgactttggg atgtgcaagg
     1681 aacacatgat ggatggagtc acgaccagga ccttctgtgg gactccggac tacattgccc
     1741 cagagataat cgcttaccag ccgtacggga agtctgtaga ttggtgggcg tacggtgtgc
     1801 tgctgtacga gatgctagcc gggcagcctc cgtttgatgg tgaagatgaa gatgaactgt
     1861 ttcagtctat aatggagcac aacgtgtcct accccaaatc cttgtccaag gaagccgtct
     1921 ctatctgcaa aggacttatg accaaacacc ctgccaagcg gctgggctgc gggcccgagg
     1981 gagagaggga tgtcagagag catgccttct tcaggagaat cgactgggag aaactggaga
     2041 acagggagat ccaaccacca ttcaagccca aagtgtgtgg caaaggagca gaaaactttg
     2101 acaagttctt cacgcgagga cagcctgtct taacaccacc agatcagctg gtcattgcta
     2161 acatagacca atctgatttt gaagggttct cgtatgtcaa cccccagttt gtgcacccaa
     2221 tcttgcaaag tgcagtatga aactcaaaaa tgaaagatca aatgcctccc cagcccccag
     2281 catccccagc agtgggaaat gatccttaac cataaaaatt taaggctatg gccttgtatt
     2341 ttgttccaca cagaggcctg gaaattctag ggacattagt caatacatga tcaacttttt
     2401 tcctcacccc ccaaccaaaa gcattatctt agtggatgat gacataaagt acagagtata
     2461 gtttaattat gtagaagtca tgtcagctac aagttgattc ttcctaaaaa aaatcaaagc
     2521 gacttggacc ctattttttt tgtacgattt gatatattct ccatactttc catttcttgg
     2581 attttcacta tcagaatcga ccagagatag taaagtgaac tcaccctaac tcaaggaaac
     2641 tcaaggaaac acttccaccc aagatgtctt tggaacaaaa gaacaggaag tccaaagaga
     2701 aagcaaagag aggttggggg ctcatatatt caagaccaca tagcttctat tctccttttc
     2761 aatggaaaca gtccctagac tcagagaggg caggatgaac ctgatcactg ttcccagtca
     2821 tcatagcaca accatagtgc acagtttaag aaggaaagaa aacttcagac aaatattcac
     2881 tgaatctacc atctgtaatc ccctgcttgg ttgataacaa tctctataac tcattctttt
     2941 taagaggcca aatcatctaa ggactttgct aaacaagcat gtgaaatcat ttcagatcaa
     3001 ggataaacca tgtgtacgtt cattctaatc tctgggagat gactcttcaa tccagggtgc
     3061 catcagtaat catgccactg ttcacgagtg ttgttagcca accccacaca cacaatattt
     3121 tgctaccttt gtaggtaccc ttcctaagaa gctgaaatgt atgaccccat ccccccccct
     3181 ttttttacta tttatttaat aagctgcagt gtcgtttatg gaagtacaat gtatagtaat
     3241 ttagtcaaag tattgactag cctcagtccc tctagattga ttttcctcct ttctctcgcc
     3301 ccacatccac ttagagatga aaaagagcat agtttgggtt cccattctca gttcctattg
     3361 aacggcacat gtggaactgt aggatcaaga tactttatgc tgatatcaac tcaaagatgt
     3421 tgtcttgcta gaaggatttt aatatgtttt gcgagtgcat catgcaatgg attttgcatg
     3481 tttataataa accttaataa cgagttaatc tatattattg atataattgt atcaactata
     3541 aagagtatta tgataatttt tataagacac aattgtgcta tatttgtgac gctcatgttt
     3601 ccagtctgct ttaagattaa gtgttagctt tattcattgc tgctgggctc tcacccgcta
     3661 ctccacacac tggcactcta tcagatatat taatttttta atgtagatgt aattttaaaa
     3721 atgaatggct actttacacg tttaactagg gttttactat atatgtgtac atatgtatat
     3781 atatatatat atatatttga ttctacctac aaaccccggt tttgtttgtg gggattattt
     3841 tttgagataa gactctgtta acttcttcat gttatcctct gttcaagttc ctttatcacc
     3901 ccttctcttg gggacagctg aatatattta attccagtat tcctgatatg ttcatatata
     3961 tgtggcattg ttacagcacc taggctgaat tgtgtgtgtg tgtgtgtctg tctgtctgtc
     4021 tgtctgtctg tctggtactt ttcagcctat gtctttgggg tctctaggga tgaaggggtg
     4081 agagaactcc tttctgtgtg tgcatatgga cacccaaaaa tatgtagtct gtctttctgc
     4141 cccagaataa ctcactgtgt acttcagaac acacagaatc cttgagacaa actttatctc
     4201 catgcctgtg tagagccatc tctgaagctg ttgccaacag actctcttca gaggcacata
     4261 ctgtcttaaa gcggttccta gaacattccg gtctttgaag agcatgcctt tgtccaaatg
     4321 cctcctaata caaggtgttt agaagaggca ggcttctgca gcataaagga taagtgaaaa
     4381 aggagttcct accagtcctt agagaaggca cctctatcga aatcatctca cagctaggct
     4441 ctcctctttg ttattctcca cctatctgct tgacagtcac ataccctgca acccaccaag
     4501 agtctttgag atacggagca taggctgttc tgaaaatccc taatcagaag gagatatgga
     4561 gtcgagagtg ggccaaacca gaaaagagca gtttcttctg caatctttca tgaattctgg
     4621 acttcagacc tcaaaaagtg gggaagggtg tcatatatgg atctcagaag tcaagttcac
     4681 catcttggta acctagcctt atcaaaaaca ctgtactcag tccaactgta aaggaactgg
     4741 cttatcaatg agccttggaa gtgaaagcat tgctcttccc aggtgggaca gcaacaggaa
     4801 gctgaacctc tcaaagtggg ggaaaccaca gagaaggagc acagggttcg tagacaatcc
     4861 accctgaggt gccaagctgc ctgactctca tgccagtagc aggcttgggt tcttccttaa
     4921 accgccagca tccagctccg agtgattcaa cttctctaga aaatgtgtgc ggttccttgg
     4981 atggcttgta cgcttagaga atacccacca acattctcac actggaggag ggaaataaca
     5041 gagccacaga ccagcaattg cctaaggaac agaacactgg agaacaaact taggagagat
     5101 gataaaaatt taaggacgtg ttcatgatgc tgcctattct atacactgct gagggttaaa
     5161 ttcagatgaa ggctagtact ttaaagatct ggacagcaga gacaactttt gctacaaaac
     5221 taactcacct ggataaccac tagcagctgt taggcaggat caattgatac tattctacat
     5281 ccttgtccca cttcacagac cttgtatgaa acagggctac agggaaacat ctgccatttg
     5341 aactgaagca accaagcagg aggccagaac caggagggtg ccttgaaggg tttaatcccc
     5401 aggggcaggg gtgggaacta tttagaatgt acctgctctc aggctgtgcc tgcattggca
     5461 gggtctgtgg aggagaacct agcacaatcc aagtctccac agggacccat caggccgtga
     5521 cccagaaaat ccattgaaat aattttgtat tatattcccc tggaaggtgg ccatttccca
     5581 ggagcagctc ttccctgttc caccacaggc cggtgggctg ctagctctgc cttcagtgtg
     5641 gcatctaaag ttacctggtg cttgggttga atggaaagag ctggagtatg ctgccaggtg
     5701 cagccccagg agttaatggg aggcttaccc caggcagcag ctaattcaga aggcagaaga
     5761 gaagccccag gagctaaact gattgccctt caccctccta cctctgtggc ctagtttgag
     5821 ctagtagcct tttctttaat ttagtctttt ttattagtaa tttgagaaac tcaggaggcc
     5881 cagagttttc cggaagcttg gtctgagatg gtcacgtgaa agattaccag aggccagtat
     5941 taaccctcaa atgttgctgc tcacaagctc cagttcttag caaataaatc atggtggctt
     6001 gccaacccca aaagagccac tcatcgatgt atcacaaaga ggaggaagca gaagtcaaca
     6061 ccattaaaga gcagggtttg agtgcaccca ggaagacatg gaaggtggtg gaaaggttgt
     6121 gttaatctgc atgggctttc cactgggggt cattgtgcaa atggaagtta ctgttcatca
     6181 gccttcaaag gtgtggcttt ttgccagata caaccttttg ttcgttctca gactctccca
     6241 actgtaacaa gtcctttgcc cagagccgag ccagccagca gaccctagaa gcacttagtt
     6301 ccatctttat ccctctgata attatggctg ctgagactag gtccagaagt cacgaaaaca
     6361 accaacaacg acctgccagc ttctgctcag cagagaaaaa taggaagggt ttgtgcaggg
     6421 ctttattttc tcaaacgcct ccacaaggca acaccacctg acagtcattt tctcaccttg
     6481 gtcttatgaa atcatctatt tcttgtgtgt acatgtcacg ctgtttcctg tttgtttaca
     6541 accctagaag ggtagggtta cctgtcccca tgccacggct gagcacatca gtcactctca
     6601 ggagatgcgt gctgagccag ggacctgaaa ggatgctgac catggggggt tggggggaca
     6661 atagcaagga aggagacagg tcctctggtt agcagtgggt ccacactaac atgacagagt
     6721 gttaggaaac tggttttaaa attgttttcc atgaactgct gttaacaaaa tgtgctggac
     6781 agtcaacacc cctgccacat ctcactgggc cagcgtagca aatctagaag aagcagatac
     6841 tttctgctgt cagaataatc cagaaaatca ggaaagggtg cttgaggcat gcacagacac
     6901 agtgttctag aaacggtgtc taatgctgtc ccagggatga tacagcaatg gttaaaaagt
     6961 gtggttggct cagcattcgt gtggtcaggt gtcagtcaat gaacagaaga cacaccaggt
     7021 tgttaaacag ccttactgtg accctcctca gaagcccaca agttccaaag acttttttta
     7081 acctaaaaca agaaattaac ttattaactc caagagagta cctgggtatc ctgggctatt
     7141 tgtacttttt tatagaggac tttaataact caattctttt caagtgagtt tttaaaataa
     7201 taaaaatttc ataaatttcc aattccatgc aacttatagg aggatttcac ccaggttgga
     7261 tagagcaccc acgatctgca ttcccacagc gggattttcc cgtgctagtg aggtctggag
     7321 tccacattgg attggctggc atttcctagc agacactaaa gatagctgtg caaggtttag
     7381 ctatcgctca actgtgggga tgacggcttt atagctcccc ttcctgatac agcccccgga
     7441 aaggattctt ggggatctac aggaccccac tcttcactgt aagagtcaga gcaggaaggg
     7501 ggtgcttctt caactctggc tcaagtcccc tctggtctct cagtctctcg catttgatta
     7561 aaatggagag atgccctcta aggattctgc ccactgggca attcaagcct cctaccccga
     7621 gaagagacag cgctgagtgt gcctgggcat ctgcgtccat gcccatggat gtgagtagac
     7681 agaaccctac ttttgagaaa acgcctatcc agcccacttt gtaagaaccc cctttttcta
     7741 aactatgaca aaaggcggct ttgcactttc tgatcaaaca acactgtctt ttgtctcctg
     7801 cttaactttt aagactattc tgtgaccgac gtttgtagat tttttttttt gttaatattt
     7861 tgcctggaaa aatgtgactc tctccttggg aggtttagta gactaataaa aattatacat
     7921 gaaggtggtt gctattttga ggctaaaggt ttttctaaga atcgccctcg tatcctgacc
     7981 gtgaaggctt ttcaggatac cttttataga cgatcagatg cattcgagct gtgtttccta
     8041 catgatttct gttttgtttt atgaaggaca cgccatgttt aaatctctca ttggaaaaaa
     8101 aaaaaaaaaa caccatgcaa aaccccaaat tggtttggag gaaggagtga aggtggaggc
     8161 tgttgcccga atgggccttt actgatgagc caggggctga tccactgctc gtttggttac
     8221 tgggcaggtg aggtagacat gtaaattact gcctagcttt cttggatttg tgtaacctct
     8281 actctccgtt tgcatgatcc gctctgttag atgcattcat tgtagttcgg aagcaagcgt
     8341 gtatgaataa agatactgat cactgctgaa aaaaaaaaaa aaaaa
//
