LOCUS       NM_001290337            1392 bp    mRNA    linear   ROD 07-AUG-2023
DEFINITION  Mus musculus prickle planar cell polarity protein 4 (Prickle4),
            mRNA.
ACCESSION   NM_001290337 XM_006525238
VERSION     NM_001290337.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1392)
  AUTHORS   Ru J, Guo D, Fan J, Zhang J, Ju R, Ouyang H, Wei L, Liu Y and Liu
            C.
  TITLE     Malformation of Tear Ducts Underlies the Epiphora and Precocious
            Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for
            Tear Duct Genesis
  JOURNAL   Invest Ophthalmol Vis Sci 61 (13), 6 (2020)
   PUBMED   33141892
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139214.12, BX525727.1 and BQ042537.1.
            
            On Mar 12, 2014 this sequence version replaced XM_006525238.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The exon combination of this
            RefSeq is inferred based on partial mouse and orthologous
            transcript alignments.
            
            CCDS Note: The exon combination of this CCDS representation is
            inferred due to a lack of full-length transcript support for this
            gene. It is supported by partial mouse and orthologous human
            transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849381
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AC139214.12        284887-285112       c
            227-371             AC139214.12        282711-282855       c
            372-432             AC139214.12        281780-281840       c
            433-821             BX525727.1         2-390
            822-1026            AC139214.12        279658-279862       c
            1027-1392           BQ042537.1         38-403
FEATURES             Location/Qualifiers
     source          1..1392
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 23.87 cM"
     gene            1..1392
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /note="prickle planar cell polarity protein 4"
                     /db_xref="GeneID:381104"
                     /db_xref="MGI:MGI:2685785"
     exon            1..226
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
     exon            227..371
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
     CDS             240..1349
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /note="translocase of outer mitochondrial membrane 6
                     homolog; prickle homolog 4"
                     /codon_start=1
                     /product="prickle-like protein 4"
                     /protein_id="NP_001277266.1"
                     /db_xref="CCDS:CCDS70823.1"
                     /db_xref="GeneID:381104"
                     /db_xref="MGI:MGI:2685785"
                     /translation="MSVQNSDWSLQQDNPIFREPDPPVYTDSDSGRRPVEDYEDTSAQ
                     AATCSSLGPPCLDINQVSNWPGFRTLLQQLPPQDSDERYCLALGEEELAQLRLFCAQR
                     KQKSLGQGVARLLPPKLEGYTCKKCKKLLDPGEYGVFAARAGEQSCWHRPCFACQACG
                     QGLINLIYFYHEGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGQRWHENHFCCQD
                     CAGPLDGGRYALPGGSPCCPSCFSKRYRSAGSSSVGVAEGQASFEEEGPDPSVGWNRA
                     SSDDKITSRAALLSAVPTLTLETLNGASKRQDRDGPQTPGSPIEDSPCPTCSSSSESE
                     PEGFFFGQRLPEPWKTPENLQADDRDISRKHCTIC"
     exon            372..479
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
     exon            480..617
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
     exon            618..821
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
     exon            822..1026
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1392
                     /gene="Prickle4"
                     /gene_synonym="Gm939"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgtgcatcg cgtagccaag tccaccggtg cctgtgccct tcttgccctg agacccacaa
       61 gcgctttcct cggtctgaag cacccgcctt gtcagggcca cttgggggcg cggccgacgg
      121 cagatctctc ctgtgctgcg ctggtgctta gccacgcaga gaccctttcg gattcttgat
      181 tcccactcct aaaccagcag ctagacaggg accccaagcg aactcggtga ctatcaccaa
      241 tgtcagttca gaattctgac tggtccctcc aacaggacaa tcctatcttc agggagccag
      301 atccaccagt ctacacagac agtgactcag gccgccggcc agtggaggac tatgaggata
      361 cctctgctca ggctgctaca tgctcgagct tgggcccacc ttgcctggat atcaaccaag
      421 tttcaaactg gcctggcttt cggactctcc tgcagcagct tcctccacag gacagtgatg
      481 aacgctactg tctggcccta ggggaggagg aactggccca acttcgactc ttctgtgccc
      541 agcggaagca gaaatccctg ggacaggggg tggcccgtct actgcctcct aagcttgaag
      601 gatacacctg taagaagtgc aagaagctac tggatccagg ggagtatgga gtgttcgcgg
      661 ccagggctgg tgagcagagc tgctggcaca gaccctgctt tgcttgccag gcctgtggcc
      721 agggcctcat aaacctcatc tacttctacc acgaggggca cctgtactgt ggccgtcatc
      781 atgcggagct cttacgacct cgatgtccag cttgtgacca gctgatcttc tcccagcgct
      841 gcactgaagc agagggacag cgctggcacg agaaccactt ctgctgccag gactgcgcag
      901 ggcccctgga tgggggacgt tatgccctgc cggggggtag cccatgctgc cccagctgct
      961 tctcaaaacg ctacagaagt gcgggctcta gctcagtagg agtagcggaa ggacaagcgt
     1021 cttttgagga agaaggaccc gatccaagcg tcggctggaa ccgtgcctcc tcggatgaca
     1081 agatcacctc ccgagctgcg cttctctctg cagttcccac tctcaccctg gaaaccctga
     1141 atggggcatc caaacggcag gatagagacg gcccacagac acccgggagt cccatagagg
     1201 acagcccctg ccccacctgc tcctcttcct ctgagtcgga acccgaaggc tttttctttg
     1261 gccagcgcct tccagagccc tggaagaccc ccgaaaacct gcaagcagat gacagagaca
     1321 tctccaggaa gcactgcacc atttgttagt ggcgcggcct ggagatcagg gtggtgggat
     1381 tggggtgggg tg
//
