LOCUS       NM_001290624            2410 bp    mRNA    linear   ROD 24-DEC-2022
DEFINITION  Mus musculus prickle planar cell polarity protein 3 (Prickle3),
            mRNA.
ACCESSION   NM_001290624 XM_006527651
VERSION     NM_001290624.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2410)
  AUTHORS   Ru J, Guo D, Fan J, Zhang J, Ju R, Ouyang H, Wei L, Liu Y and Liu
            C.
  TITLE     Malformation of Tear Ducts Underlies the Epiphora and Precocious
            Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for
            Tear Duct Genesis
  JOURNAL   Invest Ophthalmol Vis Sci 61 (13), 6 (2020)
   PUBMED   33141892
REFERENCE   2  (bases 1 to 2410)
  AUTHORS   Yu J, Liang X, Ji Y, Ai C, Liu J, Zhu L, Nie Z, Jin X, Wang C,
            Zhang J, Zhao F, Mei S, Zhao X, Zhou X, Zhang M, Wang M, Huang T,
            Jiang P and Guan MX.
  TITLE     PRICKLE3 linked to ATPase biogenesis manifested Leber's hereditary
            optic neuropathy
  JOURNAL   J Clin Invest 130 (9), 4935-4946 (2020)
   PUBMED   32516135
  REMARK    GeneRIF: PRICKLE3 linked to ATPase biogenesis manifested Leber's
            hereditary optic neuropathy.
REFERENCE   3  (bases 1 to 2410)
  AUTHORS   Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu
            HS, Brennan J, Armstrong J, Little MH, McMahon AP and
            Southard-Smith EM.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2410)
  AUTHORS   Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q,
            Qiu M, Rowitch DH, Taylor CM and Stiles CD.
  TITLE     A genome-wide screen for spatially restricted expression patterns
            identifies transcription factors that regulate glial development
  JOURNAL   J Neurosci 29 (36), 11399-11408 (2009)
   PUBMED   19741146
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672231.7, AK037217.1 and AK083704.1.
            
            [WARNING] On Dec 6, 2023 this sequence was replaced by
            NM_001290624.2.
            
            On Mar 15, 2014 this sequence version replaced XM_006527651.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049258.1, AK037217.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                AL672231.7         74135-74172
            39-370              AK037217.1         2-333
            371-1741            AK083704.1         338-1708
            1742-2410           AK083704.1         1709-2377
FEATURES             Location/Qualifiers
     source          1..2410
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 3.45 cM"
     gene            1..2410
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /note="prickle planar cell polarity protein 3"
                     /db_xref="GeneID:54630"
                     /db_xref="MGI:MGI:1859635"
     exon            1..122
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1955
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /note="prickle-like protein 3; LIM domain only protein 6;
                     triple LIM domain protein 6; prickle homolog 3"
                     /codon_start=1
                     /product="prickle planar cell polarity protein 3"
                     /protein_id="NP_001277553.1"
                     /db_xref="CCDS:CCDS72329.1"
                     /db_xref="GeneID:54630"
                     /db_xref="MGI:MGI:1859635"
                     /translation="MFARGSRRRRSGRAPPEAEDPARGQPCNSCREQCPGFLLHGWRK
                     ICQHCKCPREEHAVRTVPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKP
                     EQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAF
                     SQQRKRENLGRATVRIFPVTITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVC
                     TTCQELLVDLIYFYHAGKVYCGRHHAECLRPRCQACDEIIFSPECTEAEGRHWHMGHF
                     CCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHA
                     SDRCFCCSRCSRPLLGRPFLPRRGLIFCSRACSLGSETTAPGPGRRSWSAGTVTTPLT
                     TSTASFSATEGTSETASKGTCTKAEPAAGPEEPSHFLRGAPHRHSMPELGLRSAPEPP
                     TESPGHPAPHPDDNAFGRQSTPRVSFRDPLVSEGGPRRTLSAPPAQRRRPRSPPPRTP
                     SCHHHHHHRRRRQRHRRRGSHHHHHHPGRHGHHRCDLGSGSDSGSCSSSPSSPSSESS
                     EDDGFFLGERIPLPPHLCRPRTTQDTSTETFNSPAQPLVQESHPVMPRQTRDKNCIVA
                     "
     exon            123..208
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            209..392
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            393..506
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            507..644
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            645..848
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            849..1035
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1335
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..2410
                     /gene="Prickle3"
                     /gene_synonym="Lmo6; Pk3; Sfc16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagctgcca ggcccgacgc gccgtggcag ccgactccat tcgtcggaac cagccgtgct
       61 tgaatctgtc tgggcgcgcc atgttcgcgc gtgggtcccg gaggcgccgc tctgggcgtg
      121 cgcctccaga ggcagaggac cctgcccgcg gccagccttg caattcctgc agggaacagt
      181 gcccaggctt cctgctgcat ggctggagaa agatctgcca gcactgcaaa tgcccgcggg
      241 aggagcatgc tgtacgcact gtacctgtgg acctagaacg catcatgtgc cggctcatct
      301 cagacttcca gcgccactcc atttccgatg acgactcagg ctgtgcctca gaggagtatg
      361 cctgggtacc ccctggcctt aagccggagc aggtttacca gtttttcagt tgccttccag
      421 aggacaaggt cccctatgtc aacagtcctg gggagaaata cagaataaag cagctactgc
      481 accagctacc cccacacgac agtgaggcac agtactgcac ggccctggaa gaggaggaga
      541 agaaagagtt gcgagccttc agccagcaga ggaagcggga gaatctggga cgagccaccg
      601 ttcgaatctt cccagtgacc attactgggg ccatctgcga ggagtgtggc aagcagatcg
      661 gcggtgggga cattgcagtc tttgccagcc gcgcaggcct tggtgcctgt tggcaccctc
      721 agtgctttgt gtgtaccacg tgccaggagc tgctggttga cctcatctac ttctatcatg
      781 ctggcaaggt ctactgtggg cgccaccatg ctgagtgtct gcgtcctcgc tgccaagcgt
      841 gtgatgagat catcttctcc cctgaatgta cggaggcgga ggggcgacac tggcacatgg
      901 gtcacttctg ctgtttcgag tgtgaagctt cgttaggagg gcagcgctat gtcatgcgtc
      961 agagccgccc ccactgctgt gcctgctatg aggcccgcca tgcggaatac tgtgatggct
     1021 gtggggaaca catcggcctg gaccagggcc agatggctta tgagggccaa cactggcacg
     1081 cttcagatcg ctgcttctgc tgtagccgtt gcagtcgacc tcttctgggc cgccctttcc
     1141 tgccacgccg aggcctgatc ttctgctcac gagcctgcag ccttgggtct gagaccactg
     1201 ctccagggcc cggccgacgc agctggagcg ccggcaccgt caccacaccg ctcacaactt
     1261 ctacagcttc tttctcagct acggagggga catcagagac agccagcaaa ggcacctgta
     1321 ccaaggcaga gcctgctgca ggccctgaag agccctccca ctttctgaga ggggcccccc
     1381 accgccattc tatgcctgaa ctgggactcc gcagtgctcc tgagccaccc acagaatccc
     1441 ctggccatcc tgccccgcat ccagatgata atgcctttgg tcgccaaagt acacctcgtg
     1501 tcagcttccg agaccctctg gtgtctgaag gaggtccacg aaggaccctt agtgcacctc
     1561 cagcccagcg ccgtagacca cgaagtcccc cacccaggac ccccagctgc caccaccacc
     1621 accatcatcg ccgccggcgc cagcggcacc gccgccgagg gagccaccat caccaccacc
     1681 atcctggcag acatggccac catcgctgtg acttgggatc aggttcagat tcaggatctt
     1741 gctccagctc accctccagc cccagttcag agtcttctga ggatgatggc ttcttcctgg
     1801 gggaacgtat cccactgccc cctcacctgt gcaggcccag gaccactcag gacacctcaa
     1861 ccgaaacctt taactcccca gcccagccac ttgtccagga gtctcacccc gtgatgcctc
     1921 gccagacccg ggacaagaac tgcatcgtgg cttaaaggaa ggcaacttta gaaggaattc
     1981 tacctttcta aagtcagtgt aaatgatgat tgtcctaaac taagtcatgg tccccttctg
     2041 cactccatct tgtttgtatt agcgaagcaa tgtaatagtt gttaaagaaa caggcctggc
     2101 ttcttggatc caatggtttt gcctcaattt ccgatgctaa catcaaaaaa agttaactta
     2161 ttcattatag acttaaacat tatttttatt gtttatttag cccttcacag ctcaccccac
     2221 acagagaaaa aggttatttg tagtgggtca ctcattttgt agcttatgtg gggatatggt
     2281 tcaagcagaa ctgatgtcgg ctgctggtac tgcagagcaa aggggaatct aggcacaccc
     2341 ataaaggtgg ccacacccag atgggttgat tggcaggctg gaagacaaaa ctcccaataa
     2401 aggcactttt
//
