LOCUS       XM_036153084            5272 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus
            phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange
            factor 2 (Prex2), transcript variant X4, mRNA.
ACCESSION   XM_036153084
VERSION     XM_036153084.1
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000067.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5272
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="1"
     gene            1..5272
                     /gene="Prex2"
                     /gene_synonym="6230420N16Rik; C030045D06Rik; D430013K02;
                     Depdc2; P-Rex2"
                     /note="phosphatidylinositol-3,4,5-trisphosphate-dependent
                     Rac exchange factor 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 5 mRNAs, 3 ESTs, 75 long
                     SRA reads, 3 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 24 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:109294"
                     /db_xref="MGI:MGI:1923385"
     CDS             518..5272
                     /gene="Prex2"
                     /gene_synonym="6230420N16Rik; C030045D06Rik; D430013K02;
                     Depdc2; P-Rex2"
                     /codon_start=1
                     /product="phosphatidylinositol
                     3,4,5-trisphosphate-dependent Rac exchanger 2 protein
                     isoform X3"
                     /protein_id="XP_036008977.1"
                     /db_xref="GeneID:109294"
                     /db_xref="MGI:MGI:1923385"
                     /translation="MSDESAREVDKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHR
                     MNQCAAAKVDKNVTEETVKMLFSNIEEILIVHKEFLKVVEECLYPEPSAQQEVGACFL
                     HFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVT
                     PIQRICKYPLLLKELLKRTPRRHSDYTAVMEALQAMKAVCSNINEAKRQMEKLEVLEE
                     WQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKN
                     SKASTDGYRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCM
                     AKSPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRK
                     RKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQM
                     LYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVRDKDYHLRTYKSVVMANKL
                     IDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEEMEGSNM
                     KHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEV
                     GKKIFAINGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQ
                     IRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRP
                     MKQDSIQWVYDSLESAQEDIQKSHSKPPGDGAGDAFECKVEDVIDKFNTMAIIDGKKE
                     HVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSLTAKILEALAKSDEHFV
                     QNCTSLNSLNEVIATDLQSKFTSMCSERIEHVCHRISSYGRFSRVLKNRAWPTFKQAK
                     PKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSVEPG
                     KLSPMVYIQHTITTMAAPSGLSLGHKDGHGLQYLLKEEDLETQDIYHKLLGKLQTALK
                     EVEMSVCQIDDLLSSITYSPKLERKTTECVTPMDSDNEKGERNSKRVCFNVAGDEQED
                     SGHDTVSNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGDELPISVRISHDK
                     QDKIHTCLEQLFSQIDSIINLLKGQAVIRAFEQTKYLTPGRGLQEFQQEMEAKLSCPR
                     RLRLHLKQDPWNLPSSIQALAQSIRKHAEEVKCRILLALLEYSDSETQLRRDMVFCQS
                     LVATVCAFSEQLMAALNQMFDNSKENEMETCEASRRWLDQIANAGVLFHFQSLLSPNL
                     KDEQAMLEDTLVALFDLEKVSFFFKPSEEDPLVANVPLTYQVEGSRQALKVYFYMDSY
                     HFEQLPQRLKNGGGFKIHPVLFSQALESMEGYCYRDNISVEEFQAQINTASLEKVKQY
                     NQKLRAFYLDKSNSPPNTTSKAAYIDKLMKPLNALDELYRLITSFIRSKRIAACVNTP
                     CSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITLARSHGLPPRYIM
                     QAMDVMRKQGARVQNTAKNLGVRDRTPQSAPR"
ORIGIN      
        1 caagagcagc cctcacaagt gtccttctag gtttgggaac ctcggattag ttccatcctg
       61 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtttagtta gctggcagga tacacttccc
      121 cagggttgtg tttccttttt cctgagattt ggctaagggt aaagggtcgg agtcacatgg
      181 attgaaagca tttgattgat gtccaagtca ccgctgtggc tggagccgcc tcccctcggg
      241 ctggagccgc gtgaggccgg agcagcgggc cgggctgggt tcccgctctc cggggactgt
      301 cccgttctga gtccagcgcg tcccgcgcgt cccgcgctcg caccgcagcc cgagcacagt
      361 cctctgccca caccccggcc tccggccagc atgtgaagct acgcgttccg gctgggactc
      421 ggcagaggcg gcaactttgc tggcggcagt ggcggcagtg gcggcagcag gcgcggggca
      481 gcgcacttgc ccccagctcc gcgccccgcc ggccaccatg agcgacgaaa gcgccaggga
      541 agtagacaag cagcttcgcc tgcgcgtgtg cgtgctcagc gagctgcaga agaccgagcg
      601 cgactacgtg ggcacgctgg agttcctggt gtcggccttc ttgcatcgaa tgaaccaatg
      661 tgcagcagca aaggttgata aaaatgtgac ggaggaaaca gtgaagatgt tattctccaa
      721 tatcgaggag atcctcatcg ttcataagga gttcttgaaa gttgtagaag aatgcttata
      781 tccggaaccc agtgctcagc aggaagtggg agcctgcttc cttcacttta aggacaagtt
      841 tcgtatctat gatgaatatt gcagcaacca tgaaaaggca caaaaattgc ttcttgaact
      901 gaacaaaata agaacaatcc ggacatttct tctgaactgc atgctgcttg gaggtcggaa
      961 gaatacagac gttcccctgg aaggatattt agtgacacca attcagagga tatgcaagta
     1021 ccctcttctt ttgaaggaat tactgaagcg gactccacgg agacatagtg actacacagc
     1081 agtgatggaa gcactccaag ccatgaaagc cgtgtgttcc aacattaatg aggccaagag
     1141 acagatggag aaactggaag ttttagaaga gtggcaggca cacattgaag gctgggaggg
     1201 gtccaacatt actgacacct gtactgagat gctgatgtgt ggagtcctaa tgaaaatttc
     1261 ttccggaaat attcaagaac gagtgttttt tctttttgat aatcttttag tatactgcaa
     1321 aagaaaacac agacggctga agaatagtaa ggcatccaca gatgggtatc ggtatgtctt
     1381 tcgagggcgg atcaatactg aggtgatgga agtggaaaat gtggatgacg gcacagctga
     1441 ttttcacagc agtgggcata ttgttgtgaa tgggtggaag atacacaaca cagcaaaaaa
     1501 taaatggttt gtatgcatgg ctaaaagccc tgaagaaaag catgagtggt ttgaagctat
     1561 tttgaaagaa agagaacgtc ggaaagggtt aaaactagga atggaacaag acacctgggt
     1621 aatgatctct gagcagggtg agaaattgta taaaatgatg tgcaaacagg gaaatctgat
     1681 caaagacaga aaaagaaaac tgaccacatt tcctaagtgc ttcctgggaa gtgaatttgt
     1741 ctcatggcta ttggaaattg gagagattca caggcccgaa gaaggtgttc acttaggaca
     1801 agcgctgtta gagaatggga tcatccacca tgttaccgat aagcaccagt tcaaaccgga
     1861 gcaaatgcta taccgattcc gttatgacga tggtacattt taccccagga gtgagatgca
     1921 ggacgtgatt tctaagggtg taaggctcta ctgtcgtctt catagtctgt ttaccccagt
     1981 ggtcagagat aaagattacc atttaagaac ttacaaatct gttgtcatgg ccaacaaatt
     2041 gatagactgg ttaattgcac agggtgattg ccgtaccagg gaagaggcaa tgatatttgc
     2101 tgttgggctc tgtgacaatg gatttatgca tcacgtccta gaaaaaagtg aattcaaaga
     2161 tgagcctcta cttttccgct tttttgctga tgaggaaatg gaaggatcaa atatgaagca
     2221 taggcttatg aaacatgact tgaaggttgt ggagaatgtc atagctaagt cactgttgat
     2281 taaatccaac gaaggcagct atggctttgg cctagaagac aaaaacaaag ttccaataat
     2341 aaaattagtg gaaaaggggt cgaatgccga gatggctggc atggaagttg ggaagaagat
     2401 atttgccatt aatggtgacc ttgtttttct gagacctttt cctgaagtcg attgcttcct
     2461 gaaatcgtgc ttaaacagca gaaagccact gagagtcctc gtgagcacaa agccaagaga
     2521 gaccgttaag attccagatt ctgcagacgg gcttggtttc cagatcagag gctttggacc
     2581 ttcagttgtg catgcggtgg gaagaggtac tgtggctgca gcagctggcc ttcatccagg
     2641 acagtgtatt atcaaagtga atggaatcaa tgtcagcaaa gagacacatg ccagtgtcat
     2701 cgcacatgtc acagcctgcc ggaaatacaa acggccaatg aagcaagatt ccatacagtg
     2761 ggtctacgac agtcttgaaa gtgctcagga agacattcag aagtcccact caaagccccc
     2821 tggagacggg gctggagatg cttttgagtg caaagtagaa gatgtcattg acaagttcaa
     2881 caccatggct attattgatg gcaagaagga gcatgtgagt ctgacggtgg acaacgtcca
     2941 cctcgagtat ggggttgtat atgagtatga tagcacggcg ggcacaaagt gcaatgtggt
     3001 ggagaagatg gtggagccca aagggttctt cagcctaact gccaagattc tggaagccct
     3061 agcaaaaagt gacgaacatt ttgtccaaaa ctgcaccagc cttaattctc tgaatgaagt
     3121 gatcgccact gatcttcaga gtaaattcac cagcatgtgc agtgagagaa tcgaacatgt
     3181 gtgtcacaga atatccagct atgggaggtt ctctcgggtg ctgaagaaca gagcctggcc
     3241 cacctttaag caggccaaac ctaagatctc cccactgcac agcagtgatt tctgcccaac
     3301 caactgccac gtcaatgtga tggaagtttc ttatccgaaa acatcaactt ccctggggag
     3361 tgccttcggt gtgcagctag atagcagaaa acataattct cacgataaag aaaataaatc
     3421 tgtcgagcca gggaaactga gccccatggt gtatattcag cacacaatca caaccatggc
     3481 agcgccttcg ggcctgtcac tgggacacaa ggatgggcat ggcctccagt atttgctgaa
     3541 agaagaagac ttagaaactc aagatatcta tcacaaactt ctgggcaagc tgcagactgc
     3601 actgaaggag gtagagatga gcgtttgtca aattgatgac cttctgtctt caataacata
     3661 ttctcctaaa ttggaacgta agacaacaga gtgtgtgaca ccaatggaca gtgacaacga
     3721 gaagggagag agaaatagca aacgtgtctg ttttaatgta gcaggggatg agcaagagga
     3781 ttcaggccat gatacagtca gcaacagaga ctcttacagt gactgcaaca gcaacaggaa
     3841 ttccattgct tccttcacga gtatctgcag cagccagtgc agttcctact tccacagtga
     3901 tgagatggac tcaggtgatg agcttcctat cagtgtccgg atatctcatg ataaacaaga
     3961 caagatccac acttgcctgg aacagctctt cagccagatt gattcaataa tcaacctctt
     4021 gaaaggacaa gctgttataa gagcctttga gcagaccaag tatctcacac cgggtcgagg
     4081 attgcaagaa ttccaacagg aaatggaggc aaagctgagt tgccccagga ggttgcggct
     4141 ccatctcaag caggacccct ggaatcttcc cagcagcatc caggcgcttg cacagagcat
     4201 cagaaaacat gctgaagaag tgaagtgccg catactactg gctctccttg aatactcaga
     4261 cagtgaaacc caactccgga gagacatggt tttctgtcaa agtcttgtgg ccactgtctg
     4321 tgccttctct gagcagctca tggctgcctt aaaccagatg tttgacaaca gcaaggaaaa
     4381 tgaaatggag acttgtgaag ccagcaggag gtggctggac cagattgcaa atgctggtgt
     4441 gctttttcac ttccagtcac ttctgtcacc aaatttgaaa gatgaacaag ccatgcttga
     4501 ggatacactg gttgccctgt ttgatttgga aaaagtttcc ttcttcttca aaccatcaga
     4561 agaggatcca ctggttgcaa atgtccctct tacctaccaa gtggaaggaa gcaggcaggc
     4621 tctgaaagtt tacttctaca tggatagtta ccattttgag cagctgcccc aacggttgaa
     4681 gaatggagga gggtttaaaa ttcatcctgt tctcttttca caagcattgg agagtatgga
     4741 aggatattgc tatagagaca acatctctgt ggaagagttt caagcacaaa taaacacagc
     4801 ctccctggaa aaggtcaaac agtacaatca gaagctcagg gcattctact tggacaagtc
     4861 aaattcccca ccgaatacca catctaaagc tgcctacata gataagctca tgaagcctct
     4921 caatgcttta gatgaacttt accggctgat cacctcattt atcagatcca aacgcatcgc
     4981 tgcctgtgtg aacacacctt gcagcgcctc tggagtcgga ctgctgtcag tttcttcaga
     5041 gctgtgtgac aggctcggtg cctgtcacat catcatgtgc agcagtggtg tgcaccggtg
     5101 caccctgagt gtgacactag agcaaaccat cactttagca agaagccatg ggctccctcc
     5161 tcggtacatt atgcaggcca tggatgtgat gagaaagcag ggtgcaagag ttcagaacac
     5221 agctaaaaac ttgggcgtta gagaccggac tcctcagtca gctccaaggt aa
//
