LOCUS       NM_025596               1103 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus PRELI domain containing 1 (Prelid1), mRNA; nuclear
            gene for mitochondrial product.
ACCESSION   NM_025596
VERSION     NM_025596.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1103)
  AUTHORS   Watanabe,T., Cheng,E.C., Zhong,M. and Lin,H.
  TITLE     Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the
            piRNA pathway in the germline
  JOURNAL   Genome Res 25 (3), 368-380 (2015)
   PUBMED   25480952
REFERENCE   3  (bases 1 to 1103)
  AUTHORS   Ma,W., McKeller,M.R., Rangel,R., Ortiz-Quintero,B., Blackburn,M.R.
            and Martinez-Valdez,H.
  TITLE     Spare PRELI gene loci: failsafe chromosome insurance?
  JOURNAL   PLoS One 7 (5), e37949 (2012)
   PUBMED   22666421
  REMARK    GeneRIF: PRELI is a vital LEA B cell protein with failsafe genetics
REFERENCE   4  (bases 1 to 1103)
  AUTHORS   McKeller,M.R., Herrera-Rodriguez,S., Ma,W., Ortiz-Quintero,B.,
            Rangel,R., Cande,C., Sims-Mourtada,J.C., Melnikova,V., Kashi,C.,
            Phan,L.M., Chen,Z., Huang,P., Dunner,K. Jr., Kroemer,G., Singh,K.K.
            and Martinez-Valdez,H.
  TITLE     Vital function of PRELI and essential requirement of its LEA motif
  JOURNAL   Cell Death Dis 1 (2), e21 (2010)
   PUBMED   21364629
  REMARK    GeneRIF: PRELI interacts with OPA1 to maintain mitochondria
            structures intact, sustain balanced ion(-)/proton(+) gradients,
            promote oxidative phosphorylation reactions, regulate pro- and
            antiapoptotic protein traffic and enable cell responses to induced
            death.
REFERENCE   5  (bases 1 to 1103)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   6  (bases 1 to 1103)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1103)
  AUTHORS   Fox,E.J., Stubbs,S.A., Kyaw Tun,J., Leek,J.P., Markham,A.F. and
            Wright,S.C.
  TITLE     PRELI (protein of relevant evolutionary and lymphoid interest) is
            located within an evolutionarily conserved gene cluster on
            chromosome 5q34-q35 and encodes a novel mitochondrial protein
  JOURNAL   Biochem J 378 (Pt 3), 817-825 (2004)
   PUBMED   14640972
  REMARK    GeneRIF: Identification of PRELI (protein of relevant evolutionary
            and lymphoid interest) which encodes a mitochondrial protein and is
            located on a conserved gene cluster on chromosome 5.
REFERENCE   8  (bases 1 to 1103)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 1103)
  AUTHORS   Diaz,M., Verkoczy,L.K., Flajnik,M.F. and Klinman,N.R.
  TITLE     Decreased frequency of somatic hypermutation and impaired affinity
            maturation but intact germinal center formation in mice expressing
            antisense RNA to DNA polymerase zeta
  JOURNAL   J Immunol 167 (1), 327-335 (2001)
   PUBMED   11418667
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC025859.1.
            
            On Jul 24, 2004 this sequence version replaced NM_025596.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025859.1, BC098241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 29.8 cM"
     gene            1..1103
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /note="PRELI domain containing 1"
                     /db_xref="GeneID:66494"
                     /db_xref="MGI:MGI:1913744"
     exon            1..227
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..789
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /note="protein of relevant evolutionary and lymphoid
                     interest; PX19 homolog; PRELI domain-containing protein 1,
                     mitochondrial; px19-like protein"
                     /codon_start=1
                     /product="PRELI domain-containing protein 1, mitochondrial
                     precursor"
                     /protein_id="NP_079872.4"
                     /db_xref="CCDS:CCDS26542.1"
                     /db_xref="GeneID:66494"
                     /db_xref="MGI:MGI:1913744"
                     /translation="MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREV
                     TPDQKLLSRRLLTKTNRMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINH
                     ARLMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFGVSRAVQEFGLARFKSNVTKTMK
                     GFEYILAKLQGEAPSKTLVETAKEAKEKAKETALAATEKAKDLANKAATKQQQRQLV"
     exon            228..453
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /inference="alignment:Splign:2.1.0"
     exon            454..567
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /inference="alignment:Splign:2.1.0"
     exon            568..646
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /inference="alignment:Splign:2.1.0"
     exon            647..1089
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1063..1068
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /note="hexamer: AATAAA"
     polyA_site      1089
                     /gene="Prelid1"
                     /gene_synonym="2610524G07Rik; Preli"
                     /note="major polyA site"
ORIGIN      
        1 gcggtaggga cctgggcgcg gtcctgcgga gattgagctg cgagcctggc gggcgtgcgc
       61 ctagccacgt cccccccacc cccgggctct tcaccctgat gctgcacggg tgctgagccc
      121 gtccgggtcg ggacgatggt gaagtatttc ctgggccaga gcgtgctccg aagttcctgg
      181 gaccaagtgt tcgccgcctt ctggcaacgg tacccgaatc cctatagcaa acatgtctta
      241 accgaagaca tagtgcaccg ggaggtgacc cccgaccaga agctactgtc ccggagactc
      301 ctgaccaaga ccaacaggat gccacgttgg gcagagcgac tgtttcctgc caacgttgct
      361 cactccgtgt acatcctgga ggactctatt gtggaccccc agaatcagac catgaccacc
      421 ttcacctgga acatcaacca tgcccggctg atggtggtgg aggaacgatg tgtttactgt
      481 gtgaactctg acaatagcgg ctggaccgaa atccgtcggg aagcctgggt ctcctctagc
      541 ttatttggcg tctccagagc tgtccaggaa tttggtcttg cccggttcaa aagcaatgtg
      601 accaagacaa tgaagggctt tgaatacatc ctggccaagc tacaaggtga ggccccttcc
      661 aaaacccttg ttgagacagc caaagaggcc aaagagaaag caaaggagac cgcactggca
      721 gctacagaga aggccaagga cctggccaac aaggccgcca ccaagcagca gcagcggcag
      781 ctcgtataac tcgcttcctc tccctctccc cagtgtacgt gattattaaa gagcaacctg
      841 cagccctctc tgctgtctgg ggtggtgggt cagggccctg tcctggtcag catctgcacc
      901 acacccagct ctgtctgccg ggcagagggg tgcagtgact tgcccaaggt cacagcagtg
      961 cgcaggtgat agactgtacg ctccaagagg gcagggctcc ttgttttatt ctctgctgtg
     1021 tcccaagtac cctgaacaat atttagcaca taacaggcac tcaataaaca catgatttga
     1081 ttagccccaa aaaaaaaaaa aaa
//
