LOCUS       NM_177256               2889 bp    mRNA    linear   ROD 16-OCT-2021
DEFINITION  Mus musculus peroxiredoxin 6B (Prdx6b), mRNA.
ACCESSION   NM_177256 XM_001000674
VERSION     NM_177256.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2889)
  AUTHORS   Mo Y, Feinstein SI, Manevich Y, Zhang Q, Lu L, Ho YS and Fisher AB.
  TITLE     1-Cys peroxiredoxin knock-out mice express mRNA but not protein for
            a highly related intronless gene
  JOURNAL   FEBS Lett 555 (2), 192-198 (2003)
   PUBMED   14644414
REFERENCE   2  (bases 1 to 2889)
  AUTHORS   Lyu MS, Rhee SG, Chae HZ, Lee TH, Adamson MC, Kang SW, Jin DY,
            Jeang KT and Kozak CA.
  TITLE     Genetic mapping of six mouse peroxiredoxin genes and fourteen
            peroxiredoxin related sequences
  JOURNAL   Mamm Genome 10 (10), 1017-1019 (1999)
   PUBMED   10501973
REFERENCE   3  (bases 1 to 2889)
  AUTHORS   Phelan SA, Johnson KA, Beier DR and Paigen B.
  TITLE     Characterization of the murine gene encoding Aop2 (antioxidant
            protein 2) and identification of two highly related genes
  JOURNAL   Genomics 54 (1), 132-139 (1998)
   PUBMED   9806838
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928587.7 and AK161395.1.
            
            On Mar 25, 2011 this sequence version replaced NM_177256.4.
            
            Summary: This intronless gene is similar to the multi-exon
            peroxiredoxin 6 gene located on chromosome 1. It is transcribed and
            the ORF is intact compared to that of the peroxiredoxin 6 gene.
            This gene could be considered a transcribed pseudogene based on a
            failure to detect the protein in vivo in PMID:14644414. However,
            NCBI is representing the protein due to mass spectrometry data in
            PMID:18614015, which detected at least one peptide that is specific
            for this protein. [provided by RefSeq, Mar 2011].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK077012.1, BC087895.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AL928587.7         107024-107025
            3-1223              AK161395.1         1-1221
            1224-2889           AL928587.7         108247-109912
FEATURES             Location/Qualifiers
     source          1..2889
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 48.03 cM"
     gene            1..2889
                     /gene="Prdx6b"
                     /gene_synonym="1-cysPrx-P1; 4930414C22Rik; Aop2-rs1;
                     Prdx5-rs1; Prdx6-ps1; Prdx6-rs1; Prdx6-rs1-ps"
                     /note="peroxiredoxin 6B"
                     /db_xref="GeneID:320769"
                     /db_xref="MGI:MGI:1336888"
     exon            1..2889
                     /gene="Prdx6b"
                     /gene_synonym="1-cysPrx-P1; 4930414C22Rik; Aop2-rs1;
                     Prdx5-rs1; Prdx6-ps1; Prdx6-rs1; Prdx6-rs1-ps"
                     /inference="alignment:Splign:2.1.0"
     CDS             380..1054
                     /gene="Prdx6b"
                     /gene_synonym="1-cysPrx-P1; 4930414C22Rik; Aop2-rs1;
                     Prdx5-rs1; Prdx6-ps1; Prdx6-rs1; Prdx6-rs1-ps"
                     /note="anti-oxidant protein 2 related sequence 1;
                     peroxiredoxin 5 related sequence 1; peroxiredoxin 6,
                     pseudogene 1"
                     /codon_start=1
                     /product="peroxiredoxin 6, related sequence 1"
                     /protein_id="NP_796230.1"
                     /db_xref="CCDS:CCDS38158.1"
                     /db_xref="GeneID:320769"
                     /db_xref="MGI:MGI:1336888"
                     /translation="MPGGLLLGEEAPDFEANTTIGRIRFHDFLGNSWGMLFSHPKDFT
                     PVCTTELGRAAKLAPEFAKRNVKLIALSVDSVEDHLAWSKDINAYNGATPKEKLPFPI
                     IDDKDRDISILFCMLDPVEKDANSMPLTARGVFIFGPDKKLKMSLLYPNSTGRNFDEI
                     LRVIDSLQLTETKPVATPVDWKKGESVMVLPDLPEEEAKRCFPKGISTTKLPSGKNYL
                     RYTPQP"
ORIGIN      
        1 ggggtgcaag tttgcaacgt gctcaaatca agatggtaaa cactgagttg aattggtaac
       61 tacaaagctg aagtcgccac gatcagactc gacagtgatc aacagatact cctcaggaca
      121 cctgcatgtg aatgtacact cggcagggac tagtaaatgt aatgataatt ctaaatttat
      181 ttttcaatcc tgttctacag aagatattgc caagatatta agaagacaag ccaaaaatgg
      241 ataggaaaaa atgcaaaaga cgttgagaat agctatctaa aatctataaa taattcttaa
      301 aagtcaaaat aagaaaacga atactcggct cactgctgcg gctacgtgcc tccttgttct
      361 cagcgtcacc gctgccgcca tgcccggagg gttgcttctc ggggaagaag cccccgactt
      421 tgaggccaat accaccatcg gccgtatccg cttccacgat ttcctgggaa attcatgggg
      481 catgctcttt tcccacccaa aggactttac ccctgtgtgt accacagaac ttggtagagc
      541 tgcaaagctg gcgccagagt ttgccaagag gaatgttaag ttgattgcac tttcagtaga
      601 tagtgttgag gatcatcttg cctggagcaa ggacatcaat gcttacaatg gtgcaacacc
      661 caaagaaaag ttgccatttc ccatcattga tgataaggac agggacattt ccatcctttt
      721 ctgcatgttg gatccagtag agaaggatgc taacagcatg cctctgacgg cccggggggt
      781 gttcattttt ggccctgaca agaaactaaa gatgtctctc ctctacccta actccacggg
      841 caggaacttt gatgagattc tcagagtgat tgactctctc cagctgacag aaacaaagcc
      901 ggttgccacc ccagttgatt ggaagaaggg agagagcgtg atggtccttc ccgacctccc
      961 cgaagaggaa gccaaacgat gtttccctaa aggaatctcc accacaaagc tcccgtctgg
     1021 caaaaattac ctccgttata caccccagcc ttaagtcttt gcaggaattg gggctgcatc
     1081 tgcgcaccca gcactgggac ctgagggtgt cagccgacag cggtgggtcc ttgcagcagt
     1141 tacgtagaaa gtctgtgaca tgatcacagc cggtcttata gatcacttgc tatactcctg
     1201 ggtcattaaa tggaaatggc accaaaacct tctctgtgcc tctctttact ctgtgccttc
     1261 gccagcattt tgcccctccg cctatcacag cgtcatactg actggttttc tttgaaaaaa
     1321 ttgtatactg acaattcctt aggtctctgc aggtggtcag tgtgggctcc gtgctagaat
     1381 ggttaaacac cttttgtagc tttccgaact gaatcttctg ttacccattt tggagagcac
     1441 taacatgggg agaaactttc gattctgtat ttttagtaaa taaaatggga acagccagga
     1501 aaattgcttc ggggaatcca ttgtaagttt ctatcaaaat gggctcagaa agcctttcgc
     1561 ctcccagagt gcgcatgtac ctcctggagt ttccacattt gctctctggt gatgtctgcg
     1621 tgtgaacgca ccttataaaa gacgggcggt gacaatgttt taccactcaa tgccctagta
     1681 gtgggtggcc atttctgaat tctgcttttg ggggttcaac aaataaaatt ctgatcagaa
     1741 aaaaaaagaa agaaagaaag aaaagaaaac caatacaact ttagagaggt ccataatcac
     1801 taacagatat gtcaccaacg atgccgttca cgaggaacac aaacgtacaa aatattacag
     1861 atgctgtgct actgggtgtc agattttgtg gtaagcactt ttatccaccc aaccattctg
     1921 tttgcctgct gttgtcaaag gaaaaaaaca catcttaacg aacttaaaag caataattat
     1981 gtttttatgg caagaaagtg atcctctgcc tcctactaaa aattatcata caaaaaataa
     2041 tccttaggct cttgagctct gaagttaggc tcttgggaat ctattttatt gtttatatgt
     2101 ttgtgtataa aaaagtgaga aatctgaaag agcaaacaca ggtacatttg caaaatgata
     2161 cactagcatt tttatttaca atagcaaaga aaaactcaaa aaaaagcttc aaaagctgta
     2221 aaacactata gaacaactag ttaaactata taaattcatt tagtgaaata tatgtatgtg
     2281 tattatagaa ttattgggca cttataaaga ttaaaacatc tgggatgtgt tgtagtttta
     2341 aatggaaagc agaaagataa tctttcaata ttctcataga tgtgaaaaaa ctaaagaata
     2401 ggcagaaaaa tctaacagta atatatggag aagatggata taattttttt ttgtttttct
     2461 atcttttctt ttatcgctta ttctaatcat ggaaatgtag ctttttcagg cctaatattt
     2521 tcatagaatg attacacaac ttaccccatc acccaggcaa aagaaggaga cttcctggct
     2581 acttctttat ggtcccttaa aggctaacct taataattcc caactgattt catctcttaa
     2641 atacactcat gcaggagaat gtgggaacac aatgtgtttg gcatcgagac ttcttgtttg
     2701 caaggaatac agacatttgg caatggcaat caactagatg gggatcagga aaattggaca
     2761 tgcctgccag gtcttcacag tcattagaga ggaaatacca tccctagagt atataagaaa
     2821 agatcagaac ttttattcag caaaattaat cgacccagaa atgcaaataa aaccaattct
     2881 attcattta
//
