LOCUS       XM_006539172            9132 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus PR domain containing 16 (Prdm16),
            transcript variant X2, mRNA.
ACCESSION   XM_006539172
VERSION     XM_006539172.5
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006539172.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9132
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..9132
                     /gene="Prdm16"
                     /gene_synonym="5730557K01Rik; csp1; mel1"
                     /note="PR domain containing 16; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     mRNAs, 15 ESTs, 367 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 12 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:70673"
                     /db_xref="MGI:MGI:1917923"
     CDS             636..4466
                     /gene="Prdm16"
                     /gene_synonym="5730557K01Rik; csp1; mel1"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase PRDM16
                     isoform X2"
                     /protein_id="XP_006539235.1"
                     /db_xref="GeneID:70673"
                     /db_xref="MGI:MGI:1917923"
                     /translation="MRSKARARKLAKSDGDVVNNMYEPDPDLLAGQSAEEETEDGILS
                     PIPMGPPSPFPTSEDFTPKEGSPYEAPVYIPEDIPIPPDFELRESSIPGAGLGIWAKR
                     KMEIGERFGPYVVTPRAALKEADFGWEQMLTDTEVSSQESCIKKISEDLGSEKFCVDA
                     NQAGSGSWLKYIRVACSCDDQNLAMCQINEQIYYKVIKDIEPGEELLVHVKEGAYSLG
                     VMAPSLDEDPTFRCDECDELFQCRLDLRRHKKYACSSAGAQLYEGLGEELKPEGLGVG
                     SDGQAHECKDCERMFPNKYSLEQHMIVHTEEREYKCDQCPKAFNWKSNLIRHQMSHDS
                     GKRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTV
                     KPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKN
                     HYTPGSIFTPGLPLTPSPMMDKTKPSPTLNHGGLGFSEYFPSRPHPGSLPFSAAPPAF
                     PALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLNHAQDAKLPSPLGNPALPLVSAVSNS
                     SQGATAATGSEEKFDGRLEDAYAEKVKNRSPDMSDGSDFEDINTTTGTDLDTTTGTGS
                     DLDSDLDSDRDKGKDKGKPVESKPEFGGASVPPGAMNSVAEVPAFYSQHSFFPPPEEQ
                     LLTASGAAGDSIKAIASIAEKYFGPGFMSMQEKKLGSLPYHSVFPFQFLPNFPHSLYP
                     FTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPKEAKPALLAPKVPLIPSS
                     GEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKPGVSEGLPKVCPAQLPQQPSLHY
                     AKPSPFFMDPIYSRVEKRKVADPVGVLKEKYLRPSPLLFHPQMSAIETMTEKLESFAA
                     MKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLR
                     THTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKK
                     HEHEGAPVSQHSGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFIANSEMNQ
                     ASTRMDKRPEIQDLDSNPPCPGSASAKPEDVEEEEEEELEEEDDDSLAGKSQEDTVSP
                     TPEPQGVYEDEEDEEPPSLTMGFDHTRRCVEERGGGLLALEPTPTFGKGLDLRRAAEE
                     AFEVKDVLNSTLDSEVLKQTLYRQAKNQAYAMMLSLSEDTPLHAPSQSSLDAWLNITG
                     PSSESGAFNPINHL"
ORIGIN      
        1 cggggaccga ggggagttcg ggaggagagc gctctggggc gacggcgaac gaaagctttt
       61 taattagtaa taaaacgcaa taaaacgcag caaaagcagc ctggacccgt gtcccaacta
      121 tcagcgcgtt tgcggggaga tccaaggaag tcgcgcagaa acccgctgcg ggccagtctt
      181 ctctacggcc cggcttgggc aggagccaca gcgctgcgca gcgcagggcc agggcgggga
      241 gacggtcacc tcgcctccag ggctacctgg gtccttttaa agtgtccagg gtgcgggccc
      301 cgggcgggag cgacgagcaa ggaatgtttt cttaaagggc cagttccgag ctgcgctgaa
      361 aagggggggg gaggggggag agagagaagt gaggtgaaga ccgagaaggc ctcggagagc
      421 cccccaatcc cgcgccgagg cggcggcggc ggcggcgcga cgaagaggat gatgaacaca
      481 ttgcaaagtt tttttggccc cggcgagggg tgtcagattg agtgctctgt gcgcatgtgc
      541 gaaggtgtcc aaactgacaa tgctagggag atgaagatag tgtgtagctg cttctgggct
      601 caaggaggag gagagagatt ccgcgagccg acaccatgcg atccaaggcg agggcgagga
      661 agctagccaa aagtgacggt gacgttgtaa ataatatgta tgaacctgac ccggacctgc
      721 tggccggcca gagtgccgag gaggagaccg aagacggcat cctgtccccc atccccatgg
      781 ggccaccgtc ccccttcccc accagcgagg acttcactcc caaggagggc tcgccctatg
      841 aggctcctgt ctacattcct gaagacattc caatcccacc agacttcgag ctacgagagt
      901 cctccatacc aggagctggc ctggggatct gggccaagcg gaagatggaa atcggggaga
      961 ggtttggccc ctacgtggtg acgccccggg ccgcactgaa ggaggccgac tttggatggg
     1021 agcagatgct gacggataca gaggtgtcat cccaggagag ctgcatcaaa aagatctctg
     1081 aagacttggg tagcgagaag ttctgcgtgg atgccaatca ggcggggtct ggcagctggc
     1141 tcaagtacat ccgtgtagcg tgttcctgtg atgaccaaaa cctcgccatg tgtcagatca
     1201 acgaacagat ttactataaa gtcattaagg acatcgagcc tggagaggaa ctgttggtgc
     1261 atgtgaaaga aggtgcctac tccttgggtg tcatggcccc cagcttggat gaggacccca
     1321 cattccgctg tgatgagtgt gatgagctct tccagtgcag gctggacctg aggcgccaca
     1381 agaagtacgc gtgcagctct gcaggagccc agctctacga gggcctaggg gaggaactca
     1441 agcccgaggg ccttggcgtg ggcagcgacg ggcaagcgca tgagtgcaag gattgcgagc
     1501 ggatgttccc caacaagtac agcttggagc aacacatgat cgtccacacg gaagagcgtg
     1561 agtacaaatg tgaccagtgt cccaaggcct tcaactggaa gtccaacctc atccgccacc
     1621 agatgtctca cgacagtggc aagcgcttcg aatgtgaaaa ctgtgtcaag gtgttcacgg
     1681 accccagcaa cctccagcgt cacatccgct cacagcatgt cggtgcccgg gcccatgcct
     1741 gccctgactg tggcaagacc ttcgccacat cctctggcct caaacagcac aagcatatcc
     1801 acagcacggt gaagccattc atatgcgagg tctgccacaa gtcctacacg cagttctcca
     1861 acctgtgccg gcacaagcgg atgcacgccg actgcaggac gcagatcaag tgcaaggact
     1921 gtgggcagat gttcagcact acctcctccc tcaacaagca tcggagattc tgcgagggca
     1981 agaaccatta cacgcctggc agcatcttca ccccaggcct gcccttgacc cccagcccca
     2041 tgatggacaa gacaaaaccc tccccgaccc tcaaccacgg gggcctaggc ttcagcgagt
     2101 acttcccctc cagacctcat cctgggagcc tgcccttctc ggctgctcct ccggccttcc
     2161 ccgcactcac tccgggcttc ccgggcatct ttcctccatc cctgtaccca cgaccacctc
     2221 tgctacctcc cacgccgctg ctcaagagcc ccctgaacca cgcgcaggac gccaagctac
     2281 ccagcccgct gggaaaccca gccctgcccc ttgtctccgc ggtcagcaat agcagccagg
     2341 gtgccacagc ggccaccggg tcagaggaga aatttgatgg ccgcttggaa gacgcatatg
     2401 cggagaaggt caaaaatagg agccctgaca tgtcggatgg cagtgacttt gaggatatca
     2461 acaccacgac cgggacagac ttggacacta ccacgggcac ggggtcagac ctggacagcg
     2521 acctggacag tgacagagac aaaggcaagg acaaggggaa gccagtggag agcaaacctg
     2581 agtttggggg tgcatctgtg ccccctgggg ccatgaacag tgtggccgag gtaccggcct
     2641 tctactcaca gcattccttc ttcccgccac ccgaggaaca gctgctgacg gcctcgggag
     2701 ctgccggcga ctccatcaag gccatcgcgt ccatcgcgga gaaatacttc ggtcctggct
     2761 tcatgagcat gcaggagaag aagctgggct cactacccta ccactccgtg ttccccttcc
     2821 agttcctgcc taactttccc cactccctct acccctttac ggaccgagcc ctcgcccaca
     2881 acttgctggt caaggctgag ccaaagtcac cccgggatgc cctcaaggtg ggcggcccca
     2941 gtgcggagtg ccccttcgac ctcaccacca aaccaaaaga ggccaaaccc gccctgctcg
     3001 cacccaaggt ccccctcatc ccctcatctg gcgaggaaca gccactggac ctgagcatcg
     3061 gcagcagggc cagggcaagc cagaacggag gtggccgtga gccgcggaag aaccacgtct
     3121 acggtgaacg gaagccgggg gtcagcgagg ggctgcctaa ggtgtgccca gcacagctgc
     3181 cccagcagcc ctccttgcat tatgctaagc cttcaccgtt cttcatggat cccatctaca
     3241 gcagggtaga aaagcggaag gtggcagacc ctgtgggagt cctgaaagag aagtacctgc
     3301 ggccgtcccc acttctgttc cacccccaga tgtcagccat agaaaccatg acggagaagc
     3361 tggagagctt tgcagccatg aaggccgact caggcagctc cctgcagccc ctgcctcacc
     3421 acccgttcaa cttccgctcc ccacccccaa cgctctcgga tcccatcctc aggaagggga
     3481 aggagagata cacgtgcagg tactgtggca agatcttccc cagatctgca aatctcacaa
     3541 gacatctgag gacacacaca ggggagcagc catacaggtg caagtactgt gaccggtcat
     3601 tcagcatctc ctccaacctc cagcggcacg tgaggaacat ccacaacaaa gagaagccgt
     3661 tcaagtgcca tctgtgcaac cgctgcttcg ggcagcagac caacctagac cggcacctga
     3721 agaagcacga acacgagggc gcaccagtga gccagcactc cggggtgctc acgaaccacc
     3781 tgggcaccag cgcctcctcc cccacctccg agtcggacaa ccatgcactt ttagatgaga
     3841 aggaagattc ttacttctcc gagatccgaa acttcatcgc caacagcgag atgaaccagg
     3901 catccactcg aatggacaaa cggcctgaga tccaagacct ggacagcaac ccaccgtgtc
     3961 caggctcagc cagtgcaaag ccagaggacg tagaggagga ggaagaggag gagctggagg
     4021 aagaggatga tgacagctta gccgggaagt cacaggagga cacggtgtcc cccacacctg
     4081 agccccaagg agtctatgaa gatgaagagg atgaggaacc acccagcctg accatgggct
     4141 ttgaccatac ccggaggtgt gttgaggagc gaggaggcgg cctgttagct ttggagccga
     4201 cgccgacctt tgggaagggg ctggatctcc gcagagcagc tgaggaagca tttgaagtta
     4261 aagatgtgct taattccacc ttagattctg aggttttaaa acaaaccctg tacaggcagg
     4321 ctaagaacca ggcatatgca atgatgctgt ccctctctga agacactcct ctccacgccc
     4381 cctcccagag ctcactggat gcttggttga acatcacagg accctcgtca gagtccggag
     4441 cctttaaccc catcaaccac ctctgaggtc ctggaggccc cagggccaga gtccaaagcc
     4501 agggtaccag ctgcaggaga tggagaaggg gccagggagc agccccccac cctcaacacc
     4561 tccactttgc aaagtccagc ttctccattg aaactcagaa cccgaaggtc ccttgagtag
     4621 ccgctggcct tcatcacctc tcagaactgg cctcaaggac acgatctgca gtgggtgcgg
     4681 tgcacgggcc acccaggagc tgctcacagg agccatggat cagaaaactc gtgggcaagg
     4741 gtggggtctc tatcccagca ggagccagtt ggccacatcc aggcaactgc atggtatgaa
     4801 agaggaaatc ggaaagacgt gggcaagtgc tatggagaga gacctcatca atgattttta
     4861 taatgagaat cacatgatta agccttttgg taatcttatt gactatagag tctatttaag
     4921 catgtgggtt ttaaaaaaaa tagacggtat tttttaaaaa tcaaaaaaaa aaaaaaaaga
     4981 cttgcaaaat gtttttttaa aagtaatttt gcatcgcttt ggaatttcag cttattggca
     5041 aacccacacc tgccaggaca tcgagtacgg ctcgggtgtg ccctttataa tgtaaataat
     5101 ggagaatttt ttttctatct ctgacctgtt tgtataagcc aaggtgattc cagtgtgccc
     5161 gacacaggat aaggggcatg gagccactct gctaagtcag atgctgacta cacaagaatt
     5221 catggacgtg gtgcctggct gcaggtttgc agagggaggc caggagaaag aggtcgcctt
     5281 gccctgtgtg ctctgcagag gaatccacgg gtcccaccca agaccctccc caattgtatg
     5341 gggaagtcgg gagccagtgg ctcaggtctt ccatgctgga cacctaagga tcttcccctt
     5401 cagcagcagc actggccttg actgctgctc ttctgaaggc agggctctgg gccatgtgga
     5461 ggcctccagc cttctaccct ccccaaccct ggcaggctga tgccctcccc atggccactg
     5521 agtgtgggac gcctgcccac ctgctactcc actccaggac accaagcact acctgtgcct
     5581 aagactccag atcaatcaca cagtcgccac ttctgctctt tgtgtgggtt cctggtgaga
     5641 ataggacggg gacaggagga agatccaggg gacctgccac agcaaagaac agagacagta
     5701 cagaccccaa gaccggatgc ctcactcatt tgggacggtc agaacgtgtc tacttctctg
     5761 cttggatggg ctttaaatta tcccataggg gccaatttca aataatttct tttcctgatg
     5821 gaatttacct taatctgtat ataacttgta attttttttt ctaattcatt tctttcctta
     5881 ttttatttct tccttaacag tatttttggc attggacaac ttattctgaa gaaatgatgt
     5941 taatataagt atgtagtgaa ggaccaaacc gtgtgataag gttgtgtgct gtgtgatcgg
     6001 tacccaggga gcggggcggt gttaatgtgc caaatacccc tgtgtccctc cctccaggag
     6061 ttccacggtc accactgccc acttaccaga caatcatatg attttgttaa atttgagttt
     6121 cagttacatt ttaagacaag tgttctattt attttattgt ttggaaggag gggggcatat
     6181 cccaacaaga taagaaggaa cagagaccgc ctgggttgtc atttaaaact acaagagatt
     6241 gtgattgtgt gagcgtcagc aaactcggag cacgcgtgtc atgccgtggg cctgtcagcg
     6301 gttccctctg ggagcaactt aaacatccaa gcacagatct tttatatttg ctaaggccgt
     6361 tctgggacaa agaccgtcat ctttgctgat gctcagtggt ccaggctacg ctgggatccg
     6421 tgatggggat atcccagaag acaccattcc cctgcaggtt gcggtgaatc tcagtgacat
     6481 agcatggaac agtcagtcct gtgccgtgct cagaagcaca ctctcgagtg cacactggac
     6541 ggcctgaggc agcagggaca ctctgcagag gaacttgcca tggtccagtg gtaaggattc
     6601 gtaggtctaa ctgctcatgc ttctcatggg ttcgtgacat catctccatg gcgggccagg
     6661 cctcggcttg agaatcccag tttcctctag gtgggagcta gtcctgtgta agttcaacct
     6721 cagatataca tgccccactt ttgtaaaccc caaattatat gctttcttct cagaaagagc
     6781 aaggtgtgtg cttttttttt cccccgcggt atgactttct ctctccggta cggggagtct
     6841 atctggatgg ggatcttctg tggacctttt tgacagcagc agagcagcta aaggctccct
     6901 tctcatcctc tggcacgcac aacccctgtc catctctaac ccaagagtcc catctgtgct
     6961 gagttaaatg ctttgccccc acaaagtgat gattccaaac tcaggttatc ctgaacagtc
     7021 atccccttgg gcccagcact tggaatttga aggactccgt ccttgcttgc cacccccgac
     7081 aaagacagca cttgattttc tgcactgagt tccagatatt ctgcctctac tctgcattgc
     7141 cctcaaccag tgagctctgc ccacctggcg tctctgcagt cttaatagtg cccagctggc
     7201 tcaagcaagc atcagatcag gtacaggaga ccctctcaga gtcaggaagc tggaccaggt
     7261 gtgagttcaa aggtcttggc cactggagaa ccagaccatt aacttggctc tcttgcctgt
     7321 tgctgtgcag gatagagggg cagggcagag gttcagccac gattgtttcc caatgatact
     7381 ttccattgtt tgcacttgcc tcctcaaata gaaattcatt catcgggagg ccacctagct
     7441 tgcattccct ctagccccgg gcaaggccac acttaggccc tgtcattgct gccacaccta
     7501 ggatgatcag gtaggaaacg cagggcttca ctgtcctgca ggaaggtaga tcctgcatga
     7561 gtaagacccc gtacatccct gtgcaaaccc agggtgtaaa cctcagtaat gggagagcat
     7621 gacatggcca agcctgtggg gccctactct ccaaggccgg ggagagcagg taatctaccc
     7681 agacccagac tgacctgacc cctctgcctc ccagggtcca gacccagagc tcttggcttc
     7741 ctctccctca tctgcctcca cagtgagtgt ctgcgaagca cttgcttaaa tacatatcac
     7801 gtgttttaga ctcgaagctc aaagcactgg attgtggtcc ctgtccctgc ccaagtggct
     7861 gagacctact gagctgttca ctgtgccgtt cgaggtaggg aagaaaaggc ctccgagctg
     7921 ttgctgggac aggagggtgg agaggcctgg gacagacagc gctccctcct gccagtagac
     7981 actgggacat ccctgtccac ggagatcagc cgggtatcga aagccatgaa gactgtccct
     8041 agccctgagc gatactgtga caagacattc ttgaattctc cccagacaag gtcacttccc
     8101 ccaccattcc agccattgtc tgtctgtcac caattcacat cctcacttct aggaggggga
     8161 aaggttgagt ctttagatgt gcgattgatc cccttgcaac tgggggaagc tgggggtttc
     8221 ctcagtgtct cccacagcgc agctactctc ttcagtgtgg ggaaaggggg gccctggtgt
     8281 cagaatacgt aacttaaagc ctgtgcgtgt ggtggtgcgt ggtgtgtgtg tgtgtgcatg
     8341 tgtgctgtat gtgtgtactt tgaaccaata gtatataaat ataaatataa atatatatat
     8401 atatccctga cacccgcgag aatctccacc ctgtatgaga gttgccattg ttacattcag
     8461 atcggattca gttcgtttct gtttctgttt ttgttgttgt tgggtttttt tttttttcct
     8521 tttagaacta tatagtgttg agaaaggaat caaatgtaaa tgtctggttt ccatataacg
     8581 ttaaaaaaga aaattaaaaa accattaagg agggggctgg tgtctgccct gcccccttcc
     8641 ctgtaaattg ctgttgtgtt gataaagctg tgcatggctc gtgtttagcg gtcattattg
     8701 tgtctgtttg tggaattctt atgatgagga aaatcccgta gatgcactta ttgaatatgt
     8761 gattaggtct aagtcagggc caggagtccc aaaacgccca caagaaaaag ataaaaagaa
     8821 aaaaaaatgg accacagttc ctggtgacta tggaaatcgc cgtgagagaa tcgtgaatcg
     8881 agaagacgcg gcttgagaat agtcaaatgt gatttttttt tttttttttt ttttttgcag
     8941 atctcattct gaggcttatg gcaaagacaa atgtacttgt gtagaggttt ctgtgaggta
     9001 aaagccagga gggcctggct ttgaggtcaa tgctgtagaa taggactgac tggataccaa
     9061 atgtaatctt tccgatgcta caatgaattt atacacgaga ttgatatgca ataaatctgt
     9121 gtgtttttct aa
//
