LOCUS       XM_006539171            9135 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus PR domain containing 16 (Prdm16),
            transcript variant X1, mRNA.
ACCESSION   XM_006539171
VERSION     XM_006539171.5
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000070.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006539171.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9135
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="4"
     gene            1..9135
                     /gene="Prdm16"
                     /gene_synonym="5730557K01Rik; csp1; mel1"
                     /note="PR domain containing 16; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     mRNAs, 15 ESTs, 373 long SRA reads, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 13 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:70673"
                     /db_xref="MGI:MGI:1917923"
     CDS             636..4469
                     /gene="Prdm16"
                     /gene_synonym="5730557K01Rik; csp1; mel1"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase PRDM16
                     isoform X1"
                     /protein_id="XP_006539234.1"
                     /db_xref="GeneID:70673"
                     /db_xref="MGI:MGI:1917923"
                     /translation="MRSKARARKLAKSDGDVVNNMYEPDPDLLAGQSAEEETEDGILS
                     PIPMGPPSPFPTSEDFTPKEGSPYEAPVYIPEDIPIPPDFELRESSIPGAGLGIWAKR
                     KMEIGERFGPYVVTPRAALKEADFGWEQMLTDTEVSSQESCIKKQISEDLGSEKFCVD
                     ANQAGSGSWLKYIRVACSCDDQNLAMCQINEQIYYKVIKDIEPGEELLVHVKEGAYSL
                     GVMAPSLDEDPTFRCDECDELFQCRLDLRRHKKYACSSAGAQLYEGLGEELKPEGLGV
                     GSDGQAHECKDCERMFPNKYSLEQHMIVHTEEREYKCDQCPKAFNWKSNLIRHQMSHD
                     SGKRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHST
                     VKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGK
                     NHYTPGSIFTPGLPLTPSPMMDKTKPSPTLNHGGLGFSEYFPSRPHPGSLPFSAAPPA
                     FPALTPGFPGIFPPSLYPRPPLLPPTPLLKSPLNHAQDAKLPSPLGNPALPLVSAVSN
                     SSQGATAATGSEEKFDGRLEDAYAEKVKNRSPDMSDGSDFEDINTTTGTDLDTTTGTG
                     SDLDSDLDSDRDKGKDKGKPVESKPEFGGASVPPGAMNSVAEVPAFYSQHSFFPPPEE
                     QLLTASGAAGDSIKAIASIAEKYFGPGFMSMQEKKLGSLPYHSVFPFQFLPNFPHSLY
                     PFTDRALAHNLLVKAEPKSPRDALKVGGPSAECPFDLTTKPKEAKPALLAPKVPLIPS
                     SGEEQPLDLSIGSRARASQNGGGREPRKNHVYGERKPGVSEGLPKVCPAQLPQQPSLH
                     YAKPSPFFMDPIYSRVEKRKVADPVGVLKEKYLRPSPLLFHPQMSAIETMTEKLESFA
                     AMKADSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHL
                     RTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLK
                     KHEHEGAPVSQHSGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFIANSEMN
                     QASTRMDKRPEIQDLDSNPPCPGSASAKPEDVEEEEEEELEEEDDDSLAGKSQEDTVS
                     PTPEPQGVYEDEEDEEPPSLTMGFDHTRRCVEERGGGLLALEPTPTFGKGLDLRRAAE
                     EAFEVKDVLNSTLDSEVLKQTLYRQAKNQAYAMMLSLSEDTPLHAPSQSSLDAWLNIT
                     GPSSESGAFNPINHL"
ORIGIN      
        1 cggggaccga ggggagttcg ggaggagagc gctctggggc gacggcgaac gaaagctttt
       61 taattagtaa taaaacgcaa taaaacgcag caaaagcagc ctggacccgt gtcccaacta
      121 tcagcgcgtt tgcggggaga tccaaggaag tcgcgcagaa acccgctgcg ggccagtctt
      181 ctctacggcc cggcttgggc aggagccaca gcgctgcgca gcgcagggcc agggcgggga
      241 gacggtcacc tcgcctccag ggctacctgg gtccttttaa agtgtccagg gtgcgggccc
      301 cgggcgggag cgacgagcaa ggaatgtttt cttaaagggc cagttccgag ctgcgctgaa
      361 aagggggggg gaggggggag agagagaagt gaggtgaaga ccgagaaggc ctcggagagc
      421 cccccaatcc cgcgccgagg cggcggcggc ggcggcgcga cgaagaggat gatgaacaca
      481 ttgcaaagtt tttttggccc cggcgagggg tgtcagattg agtgctctgt gcgcatgtgc
      541 gaaggtgtcc aaactgacaa tgctagggag atgaagatag tgtgtagctg cttctgggct
      601 caaggaggag gagagagatt ccgcgagccg acaccatgcg atccaaggcg agggcgagga
      661 agctagccaa aagtgacggt gacgttgtaa ataatatgta tgaacctgac ccggacctgc
      721 tggccggcca gagtgccgag gaggagaccg aagacggcat cctgtccccc atccccatgg
      781 ggccaccgtc ccccttcccc accagcgagg acttcactcc caaggagggc tcgccctatg
      841 aggctcctgt ctacattcct gaagacattc caatcccacc agacttcgag ctacgagagt
      901 cctccatacc aggagctggc ctggggatct gggccaagcg gaagatggaa atcggggaga
      961 ggtttggccc ctacgtggtg acgccccggg ccgcactgaa ggaggccgac tttggatggg
     1021 agcagatgct gacggataca gaggtgtcat cccaggagag ctgcatcaaa aagcagatct
     1081 ctgaagactt gggtagcgag aagttctgcg tggatgccaa tcaggcgggg tctggcagct
     1141 ggctcaagta catccgtgta gcgtgttcct gtgatgacca aaacctcgcc atgtgtcaga
     1201 tcaacgaaca gatttactat aaagtcatta aggacatcga gcctggagag gaactgttgg
     1261 tgcatgtgaa agaaggtgcc tactccttgg gtgtcatggc ccccagcttg gatgaggacc
     1321 ccacattccg ctgtgatgag tgtgatgagc tcttccagtg caggctggac ctgaggcgcc
     1381 acaagaagta cgcgtgcagc tctgcaggag cccagctcta cgagggccta ggggaggaac
     1441 tcaagcccga gggccttggc gtgggcagcg acgggcaagc gcatgagtgc aaggattgcg
     1501 agcggatgtt ccccaacaag tacagcttgg agcaacacat gatcgtccac acggaagagc
     1561 gtgagtacaa atgtgaccag tgtcccaagg ccttcaactg gaagtccaac ctcatccgcc
     1621 accagatgtc tcacgacagt ggcaagcgct tcgaatgtga aaactgtgtc aaggtgttca
     1681 cggaccccag caacctccag cgtcacatcc gctcacagca tgtcggtgcc cgggcccatg
     1741 cctgccctga ctgtggcaag accttcgcca catcctctgg cctcaaacag cacaagcata
     1801 tccacagcac ggtgaagcca ttcatatgcg aggtctgcca caagtcctac acgcagttct
     1861 ccaacctgtg ccggcacaag cggatgcacg ccgactgcag gacgcagatc aagtgcaagg
     1921 actgtgggca gatgttcagc actacctcct ccctcaacaa gcatcggaga ttctgcgagg
     1981 gcaagaacca ttacacgcct ggcagcatct tcaccccagg cctgcccttg acccccagcc
     2041 ccatgatgga caagacaaaa ccctccccga ccctcaacca cgggggccta ggcttcagcg
     2101 agtacttccc ctccagacct catcctggga gcctgccctt ctcggctgct cctccggcct
     2161 tccccgcact cactccgggc ttcccgggca tctttcctcc atccctgtac ccacgaccac
     2221 ctctgctacc tcccacgccg ctgctcaaga gccccctgaa ccacgcgcag gacgccaagc
     2281 tacccagccc gctgggaaac ccagccctgc cccttgtctc cgcggtcagc aatagcagcc
     2341 agggtgccac agcggccacc gggtcagagg agaaatttga tggccgcttg gaagacgcat
     2401 atgcggagaa ggtcaaaaat aggagccctg acatgtcgga tggcagtgac tttgaggata
     2461 tcaacaccac gaccgggaca gacttggaca ctaccacggg cacggggtca gacctggaca
     2521 gcgacctgga cagtgacaga gacaaaggca aggacaaggg gaagccagtg gagagcaaac
     2581 ctgagtttgg gggtgcatct gtgccccctg gggccatgaa cagtgtggcc gaggtaccgg
     2641 ccttctactc acagcattcc ttcttcccgc cacccgagga acagctgctg acggcctcgg
     2701 gagctgccgg cgactccatc aaggccatcg cgtccatcgc ggagaaatac ttcggtcctg
     2761 gcttcatgag catgcaggag aagaagctgg gctcactacc ctaccactcc gtgttcccct
     2821 tccagttcct gcctaacttt ccccactccc tctacccctt tacggaccga gccctcgccc
     2881 acaacttgct ggtcaaggct gagccaaagt caccccggga tgccctcaag gtgggcggcc
     2941 ccagtgcgga gtgccccttc gacctcacca ccaaaccaaa agaggccaaa cccgccctgc
     3001 tcgcacccaa ggtccccctc atcccctcat ctggcgagga acagccactg gacctgagca
     3061 tcggcagcag ggccagggca agccagaacg gaggtggccg tgagccgcgg aagaaccacg
     3121 tctacggtga acggaagccg ggggtcagcg aggggctgcc taaggtgtgc ccagcacagc
     3181 tgccccagca gccctccttg cattatgcta agccttcacc gttcttcatg gatcccatct
     3241 acagcagggt agaaaagcgg aaggtggcag accctgtggg agtcctgaaa gagaagtacc
     3301 tgcggccgtc cccacttctg ttccaccccc agatgtcagc catagaaacc atgacggaga
     3361 agctggagag ctttgcagcc atgaaggccg actcaggcag ctccctgcag cccctgcctc
     3421 accacccgtt caacttccgc tccccacccc caacgctctc ggatcccatc ctcaggaagg
     3481 ggaaggagag atacacgtgc aggtactgtg gcaagatctt ccccagatct gcaaatctca
     3541 caagacatct gaggacacac acaggggagc agccatacag gtgcaagtac tgtgaccggt
     3601 cattcagcat ctcctccaac ctccagcggc acgtgaggaa catccacaac aaagagaagc
     3661 cgttcaagtg ccatctgtgc aaccgctgct tcgggcagca gaccaaccta gaccggcacc
     3721 tgaagaagca cgaacacgag ggcgcaccag tgagccagca ctccggggtg ctcacgaacc
     3781 acctgggcac cagcgcctcc tcccccacct ccgagtcgga caaccatgca cttttagatg
     3841 agaaggaaga ttcttacttc tccgagatcc gaaacttcat cgccaacagc gagatgaacc
     3901 aggcatccac tcgaatggac aaacggcctg agatccaaga cctggacagc aacccaccgt
     3961 gtccaggctc agccagtgca aagccagagg acgtagagga ggaggaagag gaggagctgg
     4021 aggaagagga tgatgacagc ttagccggga agtcacagga ggacacggtg tcccccacac
     4081 ctgagcccca aggagtctat gaagatgaag aggatgagga accacccagc ctgaccatgg
     4141 gctttgacca tacccggagg tgtgttgagg agcgaggagg cggcctgtta gctttggagc
     4201 cgacgccgac ctttgggaag gggctggatc tccgcagagc agctgaggaa gcatttgaag
     4261 ttaaagatgt gcttaattcc accttagatt ctgaggtttt aaaacaaacc ctgtacaggc
     4321 aggctaagaa ccaggcatat gcaatgatgc tgtccctctc tgaagacact cctctccacg
     4381 ccccctccca gagctcactg gatgcttggt tgaacatcac aggaccctcg tcagagtccg
     4441 gagcctttaa ccccatcaac cacctctgag gtcctggagg ccccagggcc agagtccaaa
     4501 gccagggtac cagctgcagg agatggagaa ggggccaggg agcagccccc caccctcaac
     4561 acctccactt tgcaaagtcc agcttctcca ttgaaactca gaacccgaag gtcccttgag
     4621 tagccgctgg ccttcatcac ctctcagaac tggcctcaag gacacgatct gcagtgggtg
     4681 cggtgcacgg gccacccagg agctgctcac aggagccatg gatcagaaaa ctcgtgggca
     4741 agggtggggt ctctatccca gcaggagcca gttggccaca tccaggcaac tgcatggtat
     4801 gaaagaggaa atcggaaaga cgtgggcaag tgctatggag agagacctca tcaatgattt
     4861 ttataatgag aatcacatga ttaagccttt tggtaatctt attgactata gagtctattt
     4921 aagcatgtgg gttttaaaaa aaatagacgg tattttttaa aaatcaaaaa aaaaaaaaaa
     4981 agacttgcaa aatgtttttt taaaagtaat tttgcatcgc tttggaattt cagcttattg
     5041 gcaaacccac acctgccagg acatcgagta cggctcgggt gtgcccttta taatgtaaat
     5101 aatggagaat tttttttcta tctctgacct gtttgtataa gccaaggtga ttccagtgtg
     5161 cccgacacag gataaggggc atggagccac tctgctaagt cagatgctga ctacacaaga
     5221 attcatggac gtggtgcctg gctgcaggtt tgcagaggga ggccaggaga aagaggtcgc
     5281 cttgccctgt gtgctctgca gaggaatcca cgggtcccac ccaagaccct ccccaattgt
     5341 atggggaagt cgggagccag tggctcaggt cttccatgct ggacacctaa ggatcttccc
     5401 cttcagcagc agcactggcc ttgactgctg ctcttctgaa ggcagggctc tgggccatgt
     5461 ggaggcctcc agccttctac cctccccaac cctggcaggc tgatgccctc cccatggcca
     5521 ctgagtgtgg gacgcctgcc cacctgctac tccactccag gacaccaagc actacctgtg
     5581 cctaagactc cagatcaatc acacagtcgc cacttctgct ctttgtgtgg gttcctggtg
     5641 agaataggac ggggacagga ggaagatcca ggggacctgc cacagcaaag aacagagaca
     5701 gtacagaccc caagaccgga tgcctcactc atttgggacg gtcagaacgt gtctacttct
     5761 ctgcttggat gggctttaaa ttatcccata ggggccaatt tcaaataatt tcttttcctg
     5821 atggaattta ccttaatctg tatataactt gtaatttttt tttctaattc atttctttcc
     5881 ttattttatt tcttccttaa cagtattttt ggcattggac aacttattct gaagaaatga
     5941 tgttaatata agtatgtagt gaaggaccaa accgtgtgat aaggttgtgt gctgtgtgat
     6001 cggtacccag ggagcggggc ggtgttaatg tgccaaatac ccctgtgtcc ctccctccag
     6061 gagttccacg gtcaccactg cccacttacc agacaatcat atgattttgt taaatttgag
     6121 tttcagttac attttaagac aagtgttcta tttattttat tgtttggaag gaggggggca
     6181 tatcccaaca agataagaag gaacagagac cgcctgggtt gtcatttaaa actacaagag
     6241 attgtgattg tgtgagcgtc agcaaactcg gagcacgcgt gtcatgccgt gggcctgtca
     6301 gcggttccct ctgggagcaa cttaaacatc caagcacaga tcttttatat ttgctaaggc
     6361 cgttctggga caaagaccgt catctttgct gatgctcagt ggtccaggct acgctgggat
     6421 ccgtgatggg gatatcccag aagacaccat tcccctgcag gttgcggtga atctcagtga
     6481 catagcatgg aacagtcagt cctgtgccgt gctcagaagc acactctcga gtgcacactg
     6541 gacggcctga ggcagcaggg acactctgca gaggaacttg ccatggtcca gtggtaagga
     6601 ttcgtaggtc taactgctca tgcttctcat gggttcgtga catcatctcc atggcgggcc
     6661 aggcctcggc ttgagaatcc cagtttcctc taggtgggag ctagtcctgt gtaagttcaa
     6721 cctcagatat acatgcccca cttttgtaaa ccccaaatta tatgctttct tctcagaaag
     6781 agcaaggtgt gtgctttttt tttcccccgc ggtatgactt tctctctccg gtacggggag
     6841 tctatctgga tggggatctt ctgtggacct ttttgacagc agcagagcag ctaaaggctc
     6901 ccttctcatc ctctggcacg cacaacccct gtccatctct aacccaagag tcccatctgt
     6961 gctgagttaa atgctttgcc cccacaaagt gatgattcca aactcaggtt atcctgaaca
     7021 gtcatcccct tgggcccagc acttggaatt tgaaggactc cgtccttgct tgccaccccc
     7081 gacaaagaca gcacttgatt ttctgcactg agttccagat attctgcctc tactctgcat
     7141 tgccctcaac cagtgagctc tgcccacctg gcgtctctgc agtcttaata gtgcccagct
     7201 ggctcaagca agcatcagat caggtacagg agaccctctc agagtcagga agctggacca
     7261 ggtgtgagtt caaaggtctt ggccactgga gaaccagacc attaacttgg ctctcttgcc
     7321 tgttgctgtg caggatagag gggcagggca gaggttcagc cacgattgtt tcccaatgat
     7381 actttccatt gtttgcactt gcctcctcaa atagaaattc attcatcggg aggccaccta
     7441 gcttgcattc cctctagccc cgggcaaggc cacacttagg ccctgtcatt gctgccacac
     7501 ctaggatgat caggtaggaa acgcagggct tcactgtcct gcaggaaggt agatcctgca
     7561 tgagtaagac cccgtacatc cctgtgcaaa cccagggtgt aaacctcagt aatgggagag
     7621 catgacatgg ccaagcctgt ggggccctac tctccaaggc cggggagagc aggtaatcta
     7681 cccagaccca gactgacctg acccctctgc ctcccagggt ccagacccag agctcttggc
     7741 ttcctctccc tcatctgcct ccacagtgag tgtctgcgaa gcacttgctt aaatacatat
     7801 cacgtgtttt agactcgaag ctcaaagcac tggattgtgg tccctgtccc tgcccaagtg
     7861 gctgagacct actgagctgt tcactgtgcc gttcgaggta gggaagaaaa ggcctccgag
     7921 ctgttgctgg gacaggaggg tggagaggcc tgggacagac agcgctccct cctgccagta
     7981 gacactggga catccctgtc cacggagatc agccgggtat cgaaagccat gaagactgtc
     8041 cctagccctg agcgatactg tgacaagaca ttcttgaatt ctccccagac aaggtcactt
     8101 cccccaccat tccagccatt gtctgtctgt caccaattca catcctcact tctaggaggg
     8161 ggaaaggttg agtctttaga tgtgcgattg atccccttgc aactggggga agctgggggt
     8221 ttcctcagtg tctcccacag cgcagctact ctcttcagtg tggggaaagg ggggccctgg
     8281 tgtcagaata cgtaacttaa agcctgtgcg tgtggtggtg cgtggtgtgt gtgtgtgtgc
     8341 atgtgtgctg tatgtgtgta ctttgaacca atagtatata aatataaata taaatatata
     8401 tatatatccc tgacacccgc gagaatctcc accctgtatg agagttgcca ttgttacatt
     8461 cagatcggat tcagttcgtt tctgtttctg tttttgttgt tgttgggttt tttttttttt
     8521 ccttttagaa ctatatagtg ttgagaaagg aatcaaatgt aaatgtctgg tttccatata
     8581 acgttaaaaa agaaaattaa aaaaccatta aggagggggc tggtgtctgc cctgccccct
     8641 tccctgtaaa ttgctgttgt gttgataaag ctgtgcatgg ctcgtgttta gcggtcatta
     8701 ttgtgtctgt ttgtggaatt cttatgatga ggaaaatccc gtagatgcac ttattgaata
     8761 tgtgattagg tctaagtcag ggccaggagt cccaaaacgc ccacaagaaa aagataaaaa
     8821 gaaaaaaaaa tggaccacag ttcctggtga ctatggaaat cgccgtgaga gaatcgtgaa
     8881 tcgagaagac gcggcttgag aatagtcaaa tgtgattttt tttttttttt tttttttttg
     8941 cagatctcat tctgaggctt atggcaaaga caaatgtact tgtgtagagg tttctgtgag
     9001 gtaaaagcca ggagggcctg gctttgaggt caatgctgta gaataggact gactggatac
     9061 caaatgtaat ctttccgatg ctacaatgaa tttatacacg agattgatat gcaataaatc
     9121 tgtgtgtttt tctaa
//
