LOCUS       NM_001368845            6878 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus PR domain containing 10 (Prdm10), transcript variant
            1, mRNA.
ACCESSION   NM_001368845 XM_006510464
VERSION     NM_001368845.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6878)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6878)
  AUTHORS   Han,J., Ke,C., Jiang,B., Zhou,H., Xu,H. and Xie,X.
  TITLE     Down-regulation of PR/SET domain 10 underlies natural killer cell
            dysfunction in hepatocellular carcinoma
  JOURNAL   Clin Exp Immunol 206 (3), 366-377 (2021)
   PUBMED   34562314
  REMARK    GeneRIF: Down-regulation of PR/SET domain 10 underlies natural
            killer cell dysfunction in hepatocellular carcinoma.
REFERENCE   3  (bases 1 to 6878)
  AUTHORS   Woo,J., Jin,B.H., Lee,M., Lee,E.Y., Moon,H.S., Park,J.Y. and
            Cho,Y.E.
  TITLE     Investigation of PRDM10 and PRDM13 Expression in Developing Mouse
            Embryos by an Optimized PACT-Based Embryo Clearing Method
  JOURNAL   Int J Mol Sci 22 (6), 2892 (2021)
   PUBMED   33809237
  REMARK    GeneRIF: Investigation of PRDM10 and PRDM13 Expression in
            Developing Mouse Embryos by an Optimized PACT-Based Embryo Clearing
            Method.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6878)
  AUTHORS   Han,B.Y., Seah,M.K.Y., Brooks,I.R., Quek,D.H.P., Huxley,D.R.,
            Foo,C.S., Lee,L.T., Wollmann,H., Guo,H., Messerschmidt,D.M. and
            Guccione,E.
  TITLE     Global translation during early development depends on the
            essential transcription factor PRDM10
  JOURNAL   Nat Commun 11 (1), 3603 (2020)
   PUBMED   32681107
  REMARK    GeneRIF: Global translation during early development depends on the
            essential transcription factor PRDM10.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6878)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 6878)
  AUTHORS   Park,J.A. and Kim,K.C.
  TITLE     Expression patterns of PRDM10 during mouse embryonic development
  JOURNAL   BMB Rep 43 (1), 29-33 (2010)
   PUBMED   20132732
  REMARK    GeneRIF: PRDM10 might be a transcriptional regulator for normal
            tissue differentiation during mouse embryonic development.
REFERENCE   7  (bases 1 to 6878)
  AUTHORS   Kinameri,E., Inoue,T., Aruga,J., Imayoshi,I., Kageyama,R.,
            Shimogori,T. and Moore,A.W.
  TITLE     Prdm proto-oncogene transcription factor family expression and
            interaction with the Notch-Hes pathway in mouse neurogenesis
  JOURNAL   PLoS One 3 (12), e3859 (2008)
   PUBMED   19050759
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025678.6 and AC167244.2.
            
            On or before Aug 25, 2022 this sequence version replaced
            XM_006510464.4, NM_001368845.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               CT025678.6         19611-19724         c
            115-309             AC167244.2         42706-42900
            310-474             AC167244.2         45449-45613
            475-534             AC167244.2         47791-47850
            535-742             AC167244.2         54906-55113
            743-984             AC167244.2         56595-56836
            985-1188            AC167244.2         58941-59144
            1189-1261           AC167244.2         64596-64668
            1262-1379           AC167244.2         66584-66701
            1380-1509           AC167244.2         69609-69738
            1510-1752           AC167244.2         70521-70763
            1753-1764           AC167244.2         72534-72545
            1765-2112           AC167244.2         76072-76419
            2113-2268           AC167244.2         78391-78546
            2269-2448           AC167244.2         82566-82745
            2449-2559           AC167244.2         83754-83864
            2560-2760           AC167244.2         86421-86621
            2761-2904           AC167244.2         88287-88430
            2905-3075           AC167244.2         89028-89198
            3076-3216           AC167244.2         90100-90240
            3217-3385           AC167244.2         91610-91778
            3386-3489           AC167244.2         100103-100206
            3490-6878           AC167244.2         107619-111007
FEATURES             Location/Qualifiers
     source          1..6878
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 16.77 cM"
     gene            1..6878
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /note="PR domain containing 10"
                     /db_xref="GeneID:382066"
                     /db_xref="MGI:MGI:2682952"
     exon            1..114
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            115..309
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..3693
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /note="isoform 1 is encoded by transcript variant 1; PR
                     domain zinc finger protein 10; PR domain-containing
                     protein 10"
                     /codon_start=1
                     /product="PR domain zinc finger protein 10 isoform 1"
                     /protein_id="NP_001355774.1"
                     /db_xref="GeneID:382066"
                     /db_xref="MGI:MGI:2682952"
                     /translation="MDPKDESAHVWPTSADHEQSTAQVHFVPDAGTVAQIVYTDDQVR
                     PPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPAQVAYVQQDATAQQVLPS
                     IESVHGSDPLATLQNPIARLDAKEEEEEEEDEDEDTEEEEEEDAEDTDVDDWQPDPPR
                     PFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSK
                     RRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCN
                     WMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDI
                     SEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFTRTRGRGRGRGKRR
                     FGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQ
                     ASIPIPQLPQETPPSLEQEPETHTLHLQPQQEESLVPTQTTLTADDMRRAKRIRLELQ
                     NAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISS
                     ASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHVNDGCFTCPTCKKRFPDFIQ
                     VKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLR
                     EHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHL
                     SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSI
                     RKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEYAQ
                     LPNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGD
                     YQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQTYTQHA
                     IQVQHIQVTEPAPAAPSASQVAGQPLSPSAQQVQQGLSPSHIQGSSSTQGQALQQQQN
                     SSVQHTYLPNAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTSGQVKAVTPGHYVL
                     SESQPELEEKQASALSGAVQVQPSAHSDSLDSTGPSQQQTTQYIITTTTNGNGGSEVH
                     ITKP"
     exon            310..474
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            475..534
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            535..742
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            743..984
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1188
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1261
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1379
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1509
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1752
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1764
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..2112
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2268
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            2269..2448
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            2449..2559
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            2560..2760
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            2761..2904
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..3075
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            3076..3216
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            3217..3385
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            3386..3489
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     exon            3490..6878
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6859..6864
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /note="hexamer: AATAAA"
     polyA_site      6878
                     /gene="Prdm10"
                     /gene_synonym="Gm1112; tristanin"
                     /note="major polyA site"
ORIGIN      
        1 actctgcggc gggaagaacc acctggaggc ggcggggggg tttgatttcc atcaccccta
       61 gggagagagg atccgggacc cgctgatctt ccagctcccc tcacccaacg tcgtggtgct
      121 gcgagacctt cctgccctgg atgagcacac gtgtacaggg cgtagggcac agaggagtgc
      181 tctctgtcct gcgctgctgc tgtaggtggg ccagacctgg agctgtccaa caaggaggga
      241 atggatccca aagatgaaag cgctcatgtg tggccaacgt ctgcagacca tgaacagagc
      301 actgcacagg tgcactttgt tccggatgcc ggaactgtgg ctcagattgt atacactgac
      361 gaccaagtcc gtccacccca gcaggtggtg tatacagcag atggtgcctc ctacacgtca
      421 gtggacggtc cagagcacac actggtctac atccacccgg tggaagctgc acagactctg
      481 tttacagacc cagcccaggt agcttatgtc caacaggatg ccacagctca acaggtgctg
      541 ccttccattg agagtgtgca tggttccgac cctctggcga ctctgcagaa ccccattgcc
      601 agactagatg caaaagagga agaggaagaa gaagaagatg aggatgagga tacagaggaa
      661 gaggaggaag aggatgctga agacacagat gttgatgact ggcagcctga cccgccccgg
      721 ccttttgacc cccatgactt gtggtgtgag gagtgtaaca atgcacattc ttccgtgtgc
      781 ccgaagcatg gccccttgca tcccatccct aaccggcctg tgctcacccg ggcaagagcg
      841 agcctgcctc tggtcctcta catagatagg ttcctcggag gagtgttctc caaaagacgg
      901 attcccaagc gcacccagtt cggcccagtg gaggggccgc tggtcagggg atcggagctg
      961 aaagattgct atattcatct caaggtttct cttgataaag gagacagaaa agacagggat
     1021 ttgcatgaag acctgtggtt tgagttgtcc gatgagactc tttgtaactg gatgatgttt
     1081 gtgcgcccag cccagaacca cctagaacag aacctggtag cttaccaata tggccaccat
     1141 gtgtattaca caacaataaa gaacgtggag cccaagcagg aactgaaggt gtggtacgct
     1201 gcatcctacg ctgagttcgt gaatcagaaa atccatgaca tatctgaaga agagaggaaa
     1261 gttcttcgag agcaagagaa gaactggccg tgctatgagt gcaatcggcg gtttatcagc
     1321 tcagagcagc tgcagcagca tcttaattct cacgatgaga aactggacgt gtttaccagg
     1381 actagaggga gaggaagggg tcgagggaag aggagatttg gtcctggccg gcgacccggg
     1441 cgtcctccaa aatttatccg tttggaaatc accagtgaaa atggggaaaa gagtgacgac
     1501 ggaacacagg acttgctgca tttccctaca aaggaacagt ttgatgaggc agaaccagct
     1561 actctgaatg gactagatca gccagaacaa gcgtccatcc caattcctca gctgccacag
     1621 gaaaccccgc cttctctgga gcaggaacca gaaactcaca ccttgcacct gcagccacag
     1681 caagaggaga gcctcgtgcc tacccagacc actctgacag ccgatgacat gcgcagggcc
     1741 aaacgcatcc gactggagct gcagaatgca gctcttcagc atctgtttat ccggaagtcc
     1801 ttccggcctt ttaagtgtct gcagtgtggg aaggccttcc gggaaaagga caaactggac
     1861 caacacttgc gcttccatgg gcgggagggg aactgcccgt tgacctgtga tctctgtaac
     1921 aagggcttca tcagcagcgc ctccttggag agccacatga agctgcactc ggaccagaag
     1981 acttactctt gcattttttg cccagaatcc tttgaccgcc ttgatttgtt gaaagatcat
     2041 gtggccattc atgtcaatga tggctgcttc acctgcccaa cttgtaagaa acggttccca
     2101 gattttatcc aggtgaaaaa gcacgtgcga agtttccact ctgaaaagat ctaccagtgt
     2161 acagagtgtg acaaggcctt ctgtcgcccc gacaagctga gactgcacat gctccggcat
     2221 tccgaccgca aggacttcct gtgttccacc tgcgggaagc agtttaagcg aaaagacaaa
     2281 ctccgagagc acatgcaaag gatgcataac cccgagaggg aggccaagaa agctgaccgc
     2341 atcagccgtt ccaagacctt caaaccacgg atcacatcca cagactacga cagcttcacg
     2401 ttcaagtgcc gcctgtgcat gatgggcttc cggcggcgag gcatgctggt aaatcactta
     2461 tcaaagagac atccagacat gaagatagaa gaggtgcctg agttgaccct gcccatcata
     2521 aaacccaatc gagattactt ctgtcagtat tgtgataagg tttataagag cgccagcaag
     2581 cgcaaagccc acattctgaa gaaccaccca ggagctgagc tcccgccaag tattcggaaa
     2641 ctgcgtcctg ctggccctgg agagcctgac cctatgctga gcacccacac tcagctgacg
     2701 ggtaccattg ccacccctcc tgtctgctgc ccacactgct ccaagcagta tagcagcaag
     2761 accaagatgg tgcaacacat tcgaaagaaa cacccagagt atgcccagct tcccaacacc
     2821 atccacacac cactgacgac agctgtgatc agcgccaccc cagctgtctt aacgacagat
     2881 agtgccactg gagagactgt ggtgacaaca gacctgctaa ctcaggcgat gacagaactg
     2941 tcccagacct taacaacgga ttaccgaaca cctcaggggg actaccaaag gattcagtat
     3001 atccctgtgt ctcagtcagc atctggtctg cagcagcctc agcacataca gttgcaagtg
     3061 gtgcaggtgg ctccggccac ttccccacat cagtctcagc agtccacagt ggacgttggc
     3121 cagctgcacg accctcagac ttacacgcag cacgccatcc aggtgcaaca catccaggtc
     3181 acagagcccg cccctgcggc tccgtcagca tcccaggtag ctgggcagcc attgagcccc
     3241 tctgctcagc aggtacagca ggggctcagc ccctcccata tccaaggcag ttcttccaca
     3301 caagggcagg ctctccagca gcagcagaat tcctctgtac aacacacata cctccccaat
     3361 gcttggaact ccttccgtgg ttactcatct gaaattcaaa tgatgacact gcccccaggt
     3421 cagtttgtga tcacagacag tggtgtggca acccctgtta cttctgggca agtgaaagca
     3481 gtgactccgg gtcattatgt gttatcagaa agccagccag aattggagga aaagcaagcc
     3541 tctgctctct ctggagcagt ccaggttcag ccctctgcac acagtgactc cctggactcc
     3601 acaggcccca gccaacagca gactacacag tacatcatca caaccaccac caatggcaac
     3661 gggggcagcg aagtgcacat caccaagccg tagccttcat cccatagctg gagtccagag
     3721 ctcacaccac aattttggaa tctgaagctc caaacacctc gcgacctctt tttaaagatt
     3781 tattactctc tcaagcgttt ggaaactgca gttttgacaa cgtagaccaa gggtgatttt
     3841 tgccaaggtc accttgagtc aattgactct tcaaaccctt gggatttctg ccatggaatg
     3901 cagctctttc aggggaaagt taacttctag atggaggaac ttgcgccttt gctcttgagc
     3961 tggttgtttg ttttgttttt gtttttgaac acactgacaa gccttacttg cccttcgtgg
     4021 aaatgctcag tggctggtat tatgttcata ccaaaggtgg agacaggatg taccaagtcc
     4081 gtggccactg gacttctgat atccaagcta tggcatcaaa agagaaggaa catttatttt
     4141 atgggtgtga ttaggtcagg accgctatat ctcatgcatt gagttttcag taattttaac
     4201 aaaggcagct agcttattgg ggggaaaatt aaaataagat aaaggtttga tggtggtgct
     4261 ctgaacgaaa ctgccatcta catttttctt attgctgatc tctctctttc tctctctctc
     4321 tctttcctat atggggtctt actctgctgc ccagtatagc cctgagctta tgggctaatg
     4381 ggatcctcct gccttagctg cccacgtagc tgggaccaca gtcaggcact atcatggcag
     4441 ttgtttttaa actatcttgt ttcagaaaac ctgaaacctg ggcagcagca gtcctcccta
     4501 caaatgctgt ccccaggccg atctggcctc acggtccaca agcagactcc ctggaagaca
     4561 aaaggacgca tgatctgaac aggagttgag cccctttgtt aaagctctgc ctccaggctt
     4621 tgggtatata tagctgtgtt taagaaggag atatagttct acgaaaaata tataaattat
     4681 atatatatgt atagacatat atatacaaat acatacatac ttaaggagag agagagagag
     4741 agagaaagag agagagagag agagaatgaa tgagaactga agacttggcc tgccttgcgg
     4801 gatccacata cacatattgt ccacttataa aggatgggtt ccttactcta catacataaa
     4861 ctcaggtgtt tatgtataac acttttgtgt gtgatgctag aaatcagacc cagggcctct
     4921 tgcatgctag gcaggtttcc caccactgag ctacaactcc agcccccacc tcgcactctg
     4981 gttcccagca ttgggcgtat tttagtactt tcgatctttc gatgctgtct taaaaatgaa
     5041 gattctttaa ggttgggtag aaaggtggcc tttcttactt ctaagcattt taaactttaa
     5101 gcctgtcatt aactcaccca gaccttgata taagataacc aacttcccac tgagggcaaa
     5161 aatgaaaata aagggaccat tgtaataggc tgagataaag ggatgggtgt gaaggaatat
     5221 taatgcagtt agttctgaga ggagcagttg tttgtgtgat agtggtcttc tatgtgttcc
     5281 tgtttgggag tcgtatttgc tgtggatcta gtggggaggt gtcgcccttt tttttacgac
     5341 gcattccagt tgtacccata agacatcttc aaagcctgta ttttaacaac ttttgtgaca
     5401 tatttaaaaa taattattgt agagtgaatt tatcactcca gatcagggac acctaagtta
     5461 atttcaaatg aagttaacta atttatttta tttacatttc taaggaaaaa ctgggtctgt
     5521 ggtttaagat atagagtaac ttttgggtgg taaagacgcc ctcctgaaaa gtaatcattt
     5581 ggtttgaagt cactttattt attacgtaga tcctgtgctt ccctcttggg atctcattca
     5641 tagaccatgt ctgaagattt gggcatgaaa agaacctggg aaaattacct caaaaaatgt
     5701 gtggaaactg aaaatggact ctgtatcttt gccaacaaaa aggtaacagt aatttcaaca
     5761 tgaaatgttg actccagtca cgaaatgcaa gactctgttc ccccaagtcc tgtggtgtaa
     5821 tgactgtaac tgtctcgggt tttccaaaaa gcctgtagtg ttgtaactat cccagggtct
     5881 tatccagaga gacttaggag gtaaggagcg gtagaccatc tcaaaggtac agttggagtt
     5941 tttgtaattt atatttgccc tgctggagct gggcgtggga gtgcacacct ttaatcccgc
     6001 gcttggaagg ttgagacagg attctctttg agttggaggc cggccgctcc tacaaagagt
     6061 tcaaggactg ctagggctat acacagagaa cccctgactt gaaaaaacta cacaagtaaa
     6121 taaataaatt tgatctgttg gattctcttt aatgtgagcc agcaaggtat ctcccctctt
     6181 ctcaggaata acccagtgat taaaataaag ccaatcactg aaggaatgtt ggttttatgc
     6241 cagttatttt taacttttaa aatatacaga ggaaaatact cttgaaggac cttttcatct
     6301 ctttctcttt ttttggtcct tatatgaaat aagtagatct cagaacatac accatcacta
     6361 ttctaagatc aggtatttta tgaatttatc ccgaggtgac agaagagatg gcagagtata
     6421 atccctctga cagcccaatc tgggaaacat gtggccaagg tttctatggt gatctctccc
     6481 tcccagacac attgacactg tagactgcat tcattacagc gggaatattt tgaagtgggt
     6541 tggatgtata tttttttttt tacattttta ttgtttagtt tgtgcccaga aaaatggtta
     6601 tttcatcatg taacattcct atttttctgg aaagactttt ctgttttgat gttcttgaat
     6661 tattttctga cctggaatta tcctttcaaa aaaaattctt aaaagatgta gagctaaaaa
     6721 gtacctaatg agaagctgaa gctggcccat tggttgaaag tattgattct atcttgttat
     6781 ttaaatgtga acatttattg tatattcagt gagttatagt gttaatagtc ttgtgctaca
     6841 cagcaggtgt aaaaaattaa taaatatttt tttaataa
//
