LOCUS       NM_001405929            5211 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus PR domain containing 1, with ZNF domain (Prdm1),
            transcript variant 1, mRNA.
ACCESSION   NM_001405929 XM_006512505
VERSION     NM_001405929.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5211)
  AUTHORS   Rakhymzhan,A., Fiedler,A.F., Gunther,R., Domingue,S.R.,
            Wooldridge,L., Leben,R., Cao,Y., Bias,A., Roodselaar,J., Kohler,R.,
            Ulbricht,C., Heidelin,J., Andresen,V., Beckers,I., Haibel,A.,
            Duda,G., Hauser,A.E. and Niesner,R.A.
  TITLE     Optimized intravital three-photon imaging of intact mouse tibia
            links plasma cell motility to functional states
  JOURNAL   iScience 27 (10), 110985 (2024)
   PUBMED   39391739
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5211)
  AUTHORS   Makhlouf,A., Wang,A., Sato,N., Rosa,V.S. and Shahbazi,M.N.
  TITLE     Integrin signaling in pluripotent cells acts as a gatekeeper of
            mouse germline entry
  JOURNAL   Sci Adv 10 (36), eadk2252 (2024)
   PUBMED   39231227
REFERENCE   3  (bases 1 to 5211)
  AUTHORS   Zhao,S.J., Hu,X.H., Lin,X.X., Zhang,Y.J., Wang,J., Wang,H.,
            Gong,G.S., Mor,G. and Liao,A.H.
  TITLE     IL-27/Blimp-1 axis regulates the differentiation and function of
            Tim-3+ Tregs during early pregnancy
  JOURNAL   JCI Insight 9 (16), e179233 (2024)
   PUBMED   39171524
  REMARK    GeneRIF: IL-27/Blimp-1 axis regulates the differentiation and
            function of Tim-3+ Tregs during early pregnancy.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5211)
  AUTHORS   He,J., Gao,L., Wang,P., Chan,W.K., Zheng,Y., Zhang,Y., Sun,J.,
            Li,X., Wang,J., Li,X.H., Chen,H., Yang,Z. and Wang,Y.
  TITLE     Prdm1 positively regulates liver Group 1 ILCs cancer immune
            surveillance and preserves functional heterogeneity
  JOURNAL   Elife 13, 92948 (2024)
   PUBMED   39133873
  REMARK    GeneRIF: Prdm1 positively regulates liver Group 1 ILCs cancer
            immune surveillance and preserves functional heterogeneity.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5211)
  AUTHORS   Morgan,M.A., Mould,A.W., Li,L., Robertson,E.J. and Bikoff,E.K.
  TITLE     Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities
            and corepressor interactions
  JOURNAL   Mol Cell Biol 32 (17), 3403-3413 (2012)
   PUBMED   22733990
  REMARK    GeneRIF: Alternative splicing regulates Blimp-1 recruitment of
            corepressors and DNA binding activity.
REFERENCE   6  (bases 1 to 5211)
  AUTHORS   Tunyaplin,C., Shapiro,M.A. and Calame,K.L.
  TITLE     Characterization of the B lymphocyte-induced maturation protein-1
            (Blimp-1) gene, mRNA isoforms and basal promoter
  JOURNAL   Nucleic Acids Res 28 (24), 4846-4855 (2000)
   PUBMED   11121475
REFERENCE   7  (bases 1 to 5211)
  AUTHORS   de Souza,F.S., Gawantka,V., Gomez,A.P., Delius,H., Ang,S.L. and
            Niehrs,C.
  TITLE     The zinc finger gene Xblimp1 controls anterior endomesodermal cell
            fate in Spemann's organizer
  JOURNAL   EMBO J 18 (21), 6062-6072 (1999)
   PUBMED   10545117
REFERENCE   8  (bases 1 to 5211)
  AUTHORS   Mock,B.A., Liu,L., LePaslier,D. and Huang,S.
  TITLE     The B-lymphocyte maturation promoting transcription factor
            BLIMP1/PRDI-BF1 maps to D6S447 on human chromosome 6q21-q22.1 and
            the syntenic region of mouse chromosome 10
  JOURNAL   Genomics 37 (1), 24-28 (1996)
   PUBMED   8921366
REFERENCE   9  (bases 1 to 5211)
  AUTHORS   Huang,S.
  TITLE     Blimp-1 is the murine homolog of the human transcriptional
            repressor PRDI-BF1
  JOURNAL   Cell 78 (1), 9 (1994)
   PUBMED   8033216
REFERENCE   10 (bases 1 to 5211)
  AUTHORS   Turner,C.A. Jr., Mack,D.H. and Davis,M.M.
  TITLE     Blimp-1, a novel zinc finger-containing protein that can drive the
            maturation of B lymphocytes into immunoglobulin-secreting cells
  JOURNAL   Cell 77 (2), 297-306 (1994)
   PUBMED   8168136
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC027700.11.
            
            On May 6, 2022 this sequence version replaced XM_006512505.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U08185.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               AC027700.11        140063-140271
            210-288             AC027700.11        141679-141757
            289-534             AC027700.11        141868-142113
            535-654             AC027700.11        148500-148619
            655-907             AC027700.11        151694-151946
            908-2013            AC027700.11        156574-157679
            2014-2142           AC027700.11        157951-158079
            2143-5211           AC027700.11        158496-161564
FEATURES             Location/Qualifiers
     source          1..5211
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 23.24 cM"
     gene            1..5211
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /note="PR domain containing 1, with ZNF domain"
                     /db_xref="GeneID:12142"
                     /db_xref="MGI:MGI:99655"
     exon            1..209
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            210..288
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            289..534
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            535..654
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            655..907
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            908..2013
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2142
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     exon            2143..5211
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5186..5191
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /note="hexamer: ATTAAA"
     polyA_site      5211
                     /gene="Prdm1"
                     /gene_synonym="b2b1765Clo; Blimp-1; Blimp1; PRDI-BF1;
                     ZNFPR1A1"
                     /note="major polyA site"
ORIGIN      
        1 agtgtcgcgg agacgcaaga gcagcgcgca gcacctgtcc gcccggagcg agcccggccc
       61 gcggccgtag aaaaggaggg accgccgagg tgcgcgtcag tactgctcag cccggcaggg
      121 acgcgggagg atgtggactg ggtggacatg agagaggctt atctcagatg ttggatcttc
      181 tcttggaaaa acgtgtgggt acgaccttgc caaaggctgc attttaaaac cgtgcttctt
      241 caaggcagtc tactttacac ggctttggac tcttactcaa ctgtacaagc tgcccccaag
      301 tctagctccg gctccgtgaa gtttcaagga ctggcagaga ctgggatcat gaaaatggac
      361 atggaggacg ctgatatgac tttgtggaca gaggccgagt ttgaagagaa gtgtacatac
      421 atagtgaacg accacccctg ggattccggc gctgacgggg gtacttctgt tcaagccgag
      481 gcatccttac caaggaacct gcttttcaag tatgctgcca acaacagcaa agaggttatt
      541 ggcgtggtaa gtaaggagta cataccgaag ggaacacgct ttggacccct catcggtgaa
      601 gtctacacta atgacacagt tcccaagaat gccaacagga agtatttttg gcggatctat
      661 tccagagagg agttccacca cttcattgat ggctttaatg aggagaaaag caactggatg
      721 cgctacgtga atccagctca ctctgcccgg gagcaaaacc tggctgcctg tcagaacggg
      781 atgaacatct acttctacac tattaagcct atccctgcca accaggaact tcttgtgtgg
      841 tattgtcggg actttgcgga gaggctccac tacccttatc ctggagagct cacagtgata
      901 aatctcacac aaacggaaag caacccaaag caatacagta gtgagaaaaa tgaactctac
      961 ccaaagagtg tccccaagag agagtacagc gtgaaagaaa ttctaaaact ggactccaat
     1021 ccctccaaaa ggaaggacat ctaccgttcc aacatttcac ccttcacttt agaaaaggac
     1081 atggatggct ttcggaaaaa tgggagcccc gacatgccct tctaccctcg ggtggtttat
     1141 cctatccggg cacctctgcc agaagacttt ttgaaagcgt ccctggccta tgggatggag
     1201 agacccacct acataactca cagtcccctt ccgtcttcca caactccaag tccccctgcg
     1261 agcagcagcc cggagcagag ccttaagagc tccagccccc acagcagccc gggaaacacg
     1321 gtgtcacccc tggcgccagg cctcccagaa caccgggact cctactccta cttgaatgtt
     1381 tcctatggtt ccgagggcct gggctcctac cctggctatg cacctgcccc ccacctccca
     1441 ccagctttca ttccttctta caatgctcac taccccaagt tcctgttgcc accgtacggc
     1501 attagttcca atggcttgag caccatgaac aacatcaatg gtatcaacaa cttcagcctc
     1561 ttccctaggt tgtatcccgt ctacagtaac ctccttagtg gcagcagcct gcctcatccc
     1621 atgctcaatc cagcttccct accgagttcc ctgcctaccg atggagcccg gaggctgctt
     1681 ccaccggagc accccaaaga ggtgcttatc ccagcacccc acagtgcctt ctcccttacc
     1741 ggggctgcag ccagcatgaa ggacgagagt agtcccccca gcggatctcc aacggcggga
     1801 actgcagcca cgtcagaaca cgtggtacaa cccaaagcta cctcatcagt gatggcggcc
     1861 cccagcactg acggagccat gaatctcatt aaaaacaaac gaaacatgac tggttacaag
     1921 actcttcctt accctctgaa gaaacagaat ggcaagatca agtatgagtg caatgtctgt
     1981 gccaagacgt tcggtcagct ctccaacctg aaggtccacc tgagagtgca cagtggagaa
     2041 cggcctttca agtgccagac ctgcaacaag ggttttactc agctcgccca cctgcagaaa
     2101 cactacttgg tacacacagg agagaagcca catgagtgcc aggtctgcca caagagattt
     2161 agcagcacaa gcaatctcaa gacccacctt cgattgcatt ctggagaaaa accttaccaa
     2221 tgtaaggtgt gccctgccaa gtttacgcaa tttgtgcacc tgaagctgca caagcgactg
     2281 catacccggg agcggcctca caagtgtgcc cagtgtcaca agagctacat ccatctctgc
     2341 agcctcaagg tccacctgaa gggcaactgc cctgcgggcc cagctgctgg gctgcctttg
     2401 gaggatctga cccgaatcaa tgaagaaatt gagaggttcg acatcagcga caatgcagac
     2461 cgtcttgagg acatggagga cagtgtcgat gtgacctcca tggtggagaa ggagattcta
     2521 gctgtggtca gaaaagagaa agaagaaacc agtctgaaag tgtctttgca aagaaacatg
     2581 gggaacggcc tcctctcctc agggtgcagc ctctatgagt catcggacct gtccctcatg
     2641 aagttgcctc acagcaaccc actacctctg gtgcctgtaa aggtcaaaca agaaacagtt
     2701 gaaccgatgg atccttaaga ttttcagaaa ataagtgttt cgtgttgctt cttagggtat
     2761 ggcttggtga atcagggtgc ctttagcaaa ttgcttgtac atgactccag atctgcaaag
     2821 ctccgctggc accgggtgct tccctgcacc tctctggaat taaagaagga ctccaatgtt
     2881 accaaaatct cagggcataa atgaggcaaa gactcactat atatacatat atacatatat
     2941 acatattata aatatatata tacttattta cagccatgtc tatatatttg aacctgtgta
     3001 ttttgaatat ttgtgtggat atgtttgcat agcgccttcc tattactaaa actattgcct
     3061 agccataatt attttttcaa tgataattct tcataattta ttatacagtt tatctttcaa
     3121 aaagcaataa ttaaagaagt ttacaatgac tggaaagatt ctttgtaatt tgagtataaa
     3181 tgttgtatct ttgtcctgtg gccattcttt gtagataatt tctgcacatc tgtttaaatg
     3241 cctgagactt agaagatagc tctgtgattt caggcaacct ttctctatga taatgcttta
     3301 aaatgaggtt ttgatattgc caaagtcatg tggttggtgt gttaactcag aagatcacac
     3361 aatctgagtg acattctcta agttggggat acatgtgcag aattgctcag caataatttg
     3421 aggggaagga agaagaaaaa tattttatgt ttcagaatga tggtttggtt ttcctcctcc
     3481 tagtcacaat tttaccaaac agtgacagga aggctttgcc aacctgtctc ccaatgtcac
     3541 atgaccattc tgagtggcca tatgactttg gcatccctgg gtgttatctg aaaatgtgaa
     3601 gaagataaaa aagccgtgtt cagaagatct gtcgtaaagc acagatgttg tgtgtgtgtg
     3661 tgtgtgggtt ggggggtttg agtctggctg tcattttgct gttggcttgt ttttgttttt
     3721 ttaatatcaa aattgcacaa agctggtgcc ctaccaagaa ggatttgata tagaaaggct
     3781 caggccacac ttaaaataca agcaagcaaa gagaacagaa aaaaataaaa gtaaaaacgg
     3841 gtattcttat catcttaggt taagcgggta atgaacattc ctgtccccaa cgcatcaact
     3901 gtattgtatc tgtaaaactc agcttttctc agtatttgtg tttttgcatt gtataattaa
     3961 cttaattaaa gatgaaaggg cattgcaaaa gtgttcaaca attacctcat tgagtgtatc
     4021 cagtaggagt gcaggaatta atgtcgtatc tcatgagttg ctacccagct gagcgtgtgt
     4081 gcttccaaat ggtaggctgg gtggttcggt cctgtattct cctaagccca aaggttacct
     4141 gttggtgttc aaggtgtaat aaagaatgct gtatatttat gaacctattt ataccagtat
     4201 accatgtgta tatatgatat atttataacc acttaaattg tgagccaagc catgtaaaag
     4261 aacctatttt tcctaagagc aaaaagaatc tctctgaagt tttgcttaaa actccatgac
     4321 ctcgctatga ctttggtgct tgggcaccac cctgcctact accagagagc agagcacctc
     4381 agtgcagagg tgagggtgtg tagcatcttg ggatggatag aaacaccaca ccatccagtc
     4441 gcatttgatg gccttgctac atgtgtgtca gttgggtcac agaataaaaa tcatttttct
     4501 atttctgctc tcctcttcct cttcctcttc ttcttcctct ttctctccct cctctagaac
     4561 cctgactcat gctcactgct cagtctgatg cttaccttag agttttgtat atatagatca
     4621 acttacaaag agggaaaact tcagatcctc tgggggaaac ccaagagcct tactgacctg
     4681 ttgctgtgac tagctagatg ggtttctctt taccttccaa ggatcaaaac cagagattcc
     4741 acacatgcta gcaagcaagc aagctgtcac tgggctgcag ccccaacaag actgacattt
     4801 ctggatgcat ctgtatttga gaaaaatact cacttaattg taggttaacc aaagcatgac
     4861 ctgacattga caccaaatac aaatacgatt tctttgcagt gaacttgggt tgttttcctc
     4921 ctgtgctttt cttgtgttgg gaggattttt acaaggacaa ttgcttttct tgccatctgt
     4981 cttcctctta ggcctcttac atgagagtgt tgagcccaca atgaacagtg gttggttggt
     5041 tggttggttg gtttgtttgt ttgttttttc ctcagagtta aaactgacca aagttattgg
     5101 ctttttactt tgctagaaca acaaactatc ttatgtttac gtactggttt acattgttat
     5161 ttatgtgcaa attgtcaaaa tgtaaattaa aatataaatg ttcatgcttt a
//
