LOCUS       NM_029459               2253 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus PRAME like, X-linked 1 (Pramex1), mRNA.
ACCESSION   NM_029459 XM_136073 XM_905931 XM_906050
VERSION     NM_029459.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2253)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2253)
  AUTHORS   Yang,M., Diaz,F., Krause,A.R.T., Lei,Y. and Liu,W.S.
  TITLE     Synergistic enhancement of the mouse Pramex1 and Pramel1 in
            repressing retinoic acid (RA) signaling during gametogenesis
  JOURNAL   Cell Biosci 14 (1), 28 (2024)
   PUBMED   38395975
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2253)
  AUTHORS   Lu,C., Yang,M., Rossi,R.M., Wang,A., Feitosa,W.B., Diaz,F.J. and
            Liu,W.S.
  TITLE     Deletion of the mouse X-linked Prame gene causes germ cell
            reduction in spermatogenesis
  JOURNAL   Mol Reprod Dev 87 (6), 666-679 (2020)
   PUBMED   32017313
  REMARK    GeneRIF: Deletion of the mouse X-linked Prame gene causes germ cell
            reduction in spermatogenesis.
REFERENCE   4  (bases 1 to 2253)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2253)
  AUTHORS   Zhou,J., McCarrey,J.R. and Wang,P.J.
  TITLE     A 1.1-Mb segmental deletion on the X chromosome causes meiotic
            failure in male mice
  JOURNAL   Biol Reprod 88 (6), 159 (2013)
   PUBMED   23677977
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671911.12.
            
            On May 11, 2022 this sequence version replaced NM_029459.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK015971.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               AL671911.12        97063-97224         c
            163-282             AL671911.12        96772-96891         c
            283-391             AL671911.12        96055-96163         c
            392-490             AL671911.12        93642-93740         c
            491-514             AL671911.12        90385-90408         c
            515-588             AL671911.12        89053-89126         c
            589-709             AL671911.12        87578-87698         c
            710-1009            AL671911.12        85046-85345         c
            1010-1594           AL671911.12        83982-84566         c
            1595-2253           AL671911.12        82535-83193         c
FEATURES             Location/Qualifiers
     source          1..2253
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 57.26 cM"
     gene            1..2253
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /note="PRAME like, X-linked 1"
                     /db_xref="GeneID:75829"
                     /db_xref="MGI:MGI:1923079"
     exon            1..162
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            163..282
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            283..391
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            392..490
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            491..514
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            515..588
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            589..709
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            710..1009
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     CDS             720..2108
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /codon_start=1
                     /product="preferentially expressed antigen in melanoma"
                     /protein_id="NP_083735.3"
                     /db_xref="CCDS:CCDS53190.1"
                     /db_xref="GeneID:75829"
                     /db_xref="MGI:MGI:1923079"
                     /translation="MDERDPSSLLDLAIQSLLSNELVAIHSLGEIPRELFVPLFSAAF
                     TGGYRKILTSMVKIWPFTCLHIGTLSVQEPQRELLKAMVESLQFLPAQDCSSGGPKLR
                     ILDVRQGVDCKTTCPDFGARSPTCFHGCTHSVHSILKLESQYSIVDLKPESQSAIQPM
                     ELLVDLSLDGTLREREFFALLLNKVQQSSGSLHLCCRDLQIDRFSYAKNALKFLDLTC
                     IQNLTVDQASLSEVTTLLARMIYLDSLSLSKITYRSLHGKVFRVFLNYLGRMNCLKEL
                     NLSSFSLTDHLDSLLRALPPNLDFLYLPFCEISYRDLKFLSQSAQATHLKLLNLSNNP
                     MYWDDCGPFQTLLQKLSDTLQHLAINHCHLTDAILSAILPALSKCSHLRVISFVSNPI
                     SMPMLLKILHYLTPLMELKYVIYPIPIHCYEQWQFHGRLDRQKLTDVQAQLKAMLQAA
                     KRSDMNWITYSQ"
     exon            1010..1594
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..2253
                     /gene="Pramex1"
                     /gene_synonym="4930534P07Rik; Prame"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcttccacc aaagactatg gcacgcccac cacctcgaac tcctctccag aaatgaacga
       61 ctaacactgc tgagggagtg gaaaagttaa aaaaaataag aagaaaggaa aaaaaagaaa
      121 gaaaagaaaa aaaacgaaaa gaaaatctcc aagtccgccc acttcttcat tacatccttt
      181 cactccctct tccaagattt atattcctga accattcgtg gtggcaattc ctgggctgtg
      241 agaggaattt cgaggtctgc gtcaactggg ataacgaaag tggacattat ttcaaatatt
      301 tcattgaatt tgatcagcgt ttttccatag tctcatccag agagatagat cttcactgga
      361 ttcacaactc agacacattt gaagattctt gtagagcatc tgtgagagga aggaggctgc
      421 tgcaacctaa ggcctttgtg ggtctggaac tcaggaatct cagtttctgc aatcttgacc
      481 cttactgaag tgcaccggtt ccaggaaccc atcaaatttg agtgatattt gaaagccctt
      541 tgctacggtg agattaatga agagctgtcc tgtattcttc aagaagctgg taatatttat
      601 ttcagtcagc aagttattct aaacaagaac agtgtctgag tggcaagtta ttctatccaa
      661 ggacggtgtc tgagtgtgta ccggctaata gtaaagttcc ctaaactagg tttatgatga
      721 tggatgaaag agacccatcc tcgcttttgg atctggctat acagagtcta ctaagtaatg
      781 agcttgtagc aattcattct ctgggggaga tcccaaggga gctttttgtt ccattgttct
      841 ctgctgcctt cacgggagga tataggaaga tactgacttc aatggtgaag atttggcctt
      901 ttacctgtct ccacattgga acattaagtg tacaggaacc ccagcgtgaa ctcctgaaag
      961 ccatggttga gagtcttcag tttcttcctg cccaggactg ttcttctggg ggccctaagt
     1021 tgaggatcct agatgtaagg cagggtgttg actgcaagac aacatgccct gattttggtg
     1081 ccagatctcc aacttgtttt catggttgta ctcactctgt acactctatt ctgaagttag
     1141 aaagccagta cagcattgta gatctaaagc ccgagagtca gtctgcaatc cagcctatgg
     1201 aactactagt agacctttcc cttgatggta ccttgagaga aagggaattt tttgctttgc
     1261 ttctgaataa agtacagcag agctcagggt ctttgcacct ctgctgccga gatctacaaa
     1321 ttgatagatt ttcttatgcc aaaaacgctc tgaagttcct cgatctaact tgcattcaga
     1381 acctgacagt tgatcaggct tcactgagtg aagtcaccac tcttctggct cgcatgatct
     1441 atctggacag cctgagtctc tctaaaatca cttatagatc tttgcatggg aaagtcttcc
     1501 gagtgttcct caactatctt gggcggatga actgcctgaa agagctcaac ctgtcttcct
     1561 ttagcctcac agaccatctg gatagcctcc tcagagcctt accacctaat ttggatttct
     1621 tgtatctgcc gttctgtgaa atttcttaca gagatctcaa atttctatcc cagagtgctc
     1681 aggccaccca cttaaagctg ttgaatctta gtaacaaccc aatgtattgg gatgattgtg
     1741 ggccttttca gactcttttg cagaagctct cagatacctt gcagcatctg gccataaacc
     1801 attgccattt aacagatgcc atactctctg ctattctgcc agcactatct aagtgttccc
     1861 atctccgtgt gattagcttt gtctctaacc ccatttcaat gcctatgctc ctgaaaattc
     1921 ttcattactt aacacctttg atggagctga aatacgtgat ttaccctatc cctatacatt
     1981 gctatgaaca atggcaattt catggcagat tagaccggca gaagctcacc gatgtccaag
     2041 cacaactgaa ggcaatgcta caagcagcaa aaaggagtga catgaactgg atcacttatt
     2101 ctcagtaaac ttccaagttt aactccatct caagctccaa atttgacctg ttatctgttc
     2161 aatgttcttt tctcgagctt caagaatctg atgtaagaat tcgtacgtta tagacgatta
     2221 aagttagaaa ctgatcaaaa acattaactc taa
//
