LOCUS       NM_001356546            1632 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus PRAME like 6 (Pramel6), transcript variant 4, mRNA.
ACCESSION   NM_001356546
VERSION     NM_001356546.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1632)
  AUTHORS   Madissoon E, Tohonen V, Vesterlund L, Katayama S, Unneberg P,
            Inzunza J, Hovatta O and Kere J.
  TITLE     Differences in gene expression between mouse and human for
            dynamically regulated genes in early embryo
  JOURNAL   PLoS One 9 (8), e102949 (2014)
   PUBMED   25089626
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1632)
  AUTHORS   Cinelli P, Casanova EA, Uhlig S, Lochmatter P, Matsuda T, Yokota T,
            Rulicke T, Ledermann B and Burki K.
  TITLE     Expression profiling in transgenic FVB/N embryonic stem cells
            overexpressing STAT3
  JOURNAL   BMC Dev Biol 8, 57 (2008)
   PUBMED   18500982
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1632)
  AUTHORS   Kaji K, Nichols J and Hendrich B.
  TITLE     Mbd3, a component of the NuRD co-repressor complex, is required for
            development of pluripotent cells
  JOURNAL   Development 134 (6), 1123-1132 (2007)
   PUBMED   17287250
REFERENCE   4  (bases 1 to 1632)
  AUTHORS   Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco
            G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T,
            Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T,
            Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ,
            Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A,
            Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso
            J, Hide W and Ko MS.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   5  (bases 1 to 1632)
  AUTHORS   Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R,
            Page DC and Jaenisch R.
  TITLE     Incomplete reactivation of Oct4-related genes in mouse embryos
            cloned from somatic nuclei
  JOURNAL   Development 130 (8), 1673-1680 (2003)
   PUBMED   12620990
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928797.6 and AF490342.1.
            
            Transcript Variant: This variant (4) differs in the 5' UTR compared
            to variant 1. All four variants encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: AF490342.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AL928797.6         133737-133801
            66-379              AL928797.6         135603-135916
            380-427             AL928797.6         136353-136400
            428-1632            AF490342.1         336-1540
FEATURES             Location/Qualifiers
     source          1..1632
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.86 cM"
     gene            1..1632
                     /gene="Pramel6"
                     /note="PRAME like 6"
                     /db_xref="GeneID:347711"
                     /db_xref="MGI:MGI:2156390"
     exon            1..65
                     /gene="Pramel6"
                     /inference="alignment:Splign:2.1.0"
     exon            66..379
                     /gene="Pramel6"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..1550
                     /gene="Pramel6"
                     /codon_start=1
                     /product="preferentially expressed antigen in melanoma
                     like 6"
                     /protein_id="NP_001343475.1"
                     /db_xref="CCDS:CCDS16294.1"
                     /db_xref="GeneID:347711"
                     /db_xref="MGI:MGI:2156390"
                     /translation="MSVDSLPTLFQWARDNLLKEEALAISALEELPIHLFPEMFKVAF
                     TDRHTKVLIAMVSAWPFPCLPVGTLIEDPHLETLKAVLDGLNVLVTGKVHSSRCKLRV
                     LDLRRNVHHDFWSIQTGSHEDNCPAQIVAQKQPVETCPNPRREIPFMVVTDFELTQES
                     FDEWTIYLMQWIQERKSSIHLCCRKLNSCASPVSNVIEIFKLVDLNCILELQLSQWWP
                     EVLEELDPYLEGMNNLHTLMLEGLKPFRFTACEEDQEDEWQSTLPSLLSNFGSLQNLY
                     LNDIYLLEDSLDKWLGCLKTPLKTLSITDCPRLLQSDFECLPNCPNICKLKHLNLNAL
                     FLSDVGYEIPGLILEKVTSTLQILELERCGMTDPHFKALMPALSKCSQLLKVSFCHND
                     ISLRVLKTLLCHTAKLSQLTQELYPAPQECYEDYKILKDRFKKLCPELLNILKAKRQP
                     KKVSFTTQTCLKCLHSCHYYYNLEATDCLCQCICQ"
     exon            380..967
                     /gene="Pramel6"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1632
                     /gene="Pramel6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagccactt ggagtcacca cttatcgatg ctgggatcta gagattttta ccgtgttcaa
       61 atcaggatca tttttcctga aaatcagtca caatgagtgt tgactcccta cccaccctct
      121 ttcagtgggc aagagacaat ctactgaagg aggaagcttt agccatttct gctctggagg
      181 aactgcccat tcatctattc ccagagatgt tcaaggtagc cttcactgat aggcatacaa
      241 aggtcctgat tgcaatggtg tctgcctggc ccttcccatg ccttcctgta ggaaccctaa
      301 tagaggaccc acatctggag actttgaaag cagtgcttga tgggttgaat gtcctggtaa
      361 cagggaaggt tcattccagt aggtgcaaac tcagagtcct tgatttgagg aggaatgtgc
      421 accatgactt ctggagcata cagactggat cccatgaaga taactgccca gcacagatcg
      481 tggcacagaa gcagccagtg gagacctgcc ctaaccctag aagggagata ccttttatgg
      541 tggtgaccga ctttgaactc acgcaggaga gtttcgatga atggaccata tacttgatgc
      601 agtggatcca ggagagaaaa tcttccattc atctatgctg taggaagctg aacagttgtg
      661 cctcaccagt ctctaatgtc atagagatct ttaaattggt ggatttaaac tgtatcctgg
      721 agctacagct gagtcagtgg tggcctgaag tcctggaaga acttgatcct tacctggagg
      781 gaatgaataa tcttcacaca ctcatgttag agggattgaa gcccttcaga tttactgctt
      841 gtgaagaaga ccaggaagac gagtggcaaa gcacgttgcc ttctctgctc tccaactttg
      901 gcagtctcca gaatctctat ttgaatgata tctaccttct agaagactcc cttgacaagt
      961 ggcttggctg cctgaagacc cctttgaaga ccttgtcaat tacggactgc cctaggctct
     1021 tacagtcaga cttcgagtgc ctgccaaatt gtccgaatat ttgtaagctc aagcatctga
     1081 acctgaatgc tctgtttcta tctgatgtag gctatgagat tccagggctc atccttgaga
     1141 aagtcacaag taccctgcaa attctggaac tggagaggtg tggaatgaca gaccctcatt
     1201 tcaaagccct catgcctgct ctgagcaaat gctcccagct ccttaaagtc agcttctgtc
     1261 ataatgatat ctccctgcgt gtcctgaaga cccttctttg tcacacagcc aaactgagcc
     1321 agctgaccca ggagctgtac cctgcccctc aggaatgcta tgaggattac aagatactta
     1381 aagacagatt taagaaactt tgtccagaac tgctgaacat acttaaggcc aaaaggcagc
     1441 ccaagaaagt ctcttttact acacaaacct gcttgaagtg tttacattcc tgtcattatt
     1501 attataacct ggaggctaca gattgccttt gtcagtgcat ttgtcagtaa gtagaataag
     1561 gttgcttctg gtaccaagaa ttgagcacta tgtatgtgga tgtccttatt tgcatgtaat
     1621 aaatattctg ag
//
